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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFPEVLDGRVKTLHPRVHAGLLADL
RKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRA
GGFTLAERKRLASLAFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPGLA
QAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRKAHECDPLSAYGGVIAANTEVSVE
MAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPA
DPATLTDLVFAWRACRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLETLAAAG
VTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH

The query sequence (length=517) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3zzm:A 520 517 1.0000 0.9942 1.0000 0.0 4a1o:A, 4a1o:B
2 2b1g:A 590 481 0.3211 0.2814 0.3451 1.52e-67 2b1g:D, 2b1i:A, 2b1i:B, 1g8m:A, 2iu0:B, 2iu3:B, 1m9n:A, 1m9n:B, 1oz0:A, 1oz0:B, 1thz:A, 1thz:B
3 2b1g:A 590 56 0.0503 0.0441 0.4643 6.64e-07 2b1g:D, 2b1i:A, 2b1i:B, 1g8m:A, 2iu0:B, 2iu3:B, 1m9n:A, 1m9n:B, 1oz0:A, 1oz0:B, 1thz:A, 1thz:B
4 1p4r:A 589 481 0.3153 0.2767 0.3389 1.16e-64 1p4r:B, 1pkx:A, 1pkx:C, 1pl0:A, 1pl0:B, 1pl0:C, 1pl0:D, 5uy8:A, 5uy8:B, 5uy8:C, 5uy8:D, 5uz0:A, 5uz0:B, 5uz0:C, 5uz0:D
5 1p4r:A 589 64 0.0464 0.0407 0.3750 2.03e-05 1p4r:B, 1pkx:A, 1pkx:C, 1pl0:A, 1pl0:B, 1pl0:C, 1pl0:D, 5uy8:A, 5uy8:B, 5uy8:C, 5uy8:D, 5uz0:A, 5uz0:B, 5uz0:C, 5uz0:D
6 7mgq:A 602 473 0.3037 0.2608 0.3319 2.54e-60 7mgq:B, 7mgq:C, 7mgq:D
7 7mgq:A 602 141 0.0832 0.0714 0.3050 1.26e-07 7mgq:B, 7mgq:C, 7mgq:D
8 1ker:B 347 117 0.0600 0.0893 0.2650 3.5 1kep:A, 1kep:B, 1ker:A, 1ket:A, 1ket:B, 1oc2:A, 1oc2:B
9 7lvb:F 108 57 0.0348 0.1667 0.3158 6.2 2chb:D, 2chb:E, 2chb:F, 2chb:G, 2chb:H, 3chb:D, 3chb:E, 3chb:F, 3chb:G, 3chb:H, 1ct1:F, 1ct1:G, 1ct1:H, 1eei:D, 1eei:E, 1eei:F, 1eei:G, 1eei:H, 3efx:D, 3efx:E, 3efx:F, 3efx:G, 3efx:H, 3efx:I, 3efx:J, 3efx:K, 3efx:L, 3efx:M, 5elb:A, 5elb:B, 5elb:C, 5elb:D, 5elb:E, 5elb:F, 5elb:G, 5elb:H, 5elb:I, 5elb:J, 5elc:A, 5elc:B, 5elc:C, 5elc:D, 5elc:E, 5elc:G, 5elc:H, 5elc:I, 5elc:J, 5elc:F, 5eld:A, 5eld:C, 5eld:D, 5eld:E, 5ele:D, 5ele:G, 5ele:J, 5ele:A, 5ele:F, 5ele:H, 5ele:I, 5elf:A, 5elf:D, 5elf:E, 5elf:F, 5elf:G, 5elf:I, 5elf:J, 5elf:B, 5elf:H, 1g8z:D, 1g8z:F, 1g8z:G, 1g8z:H, 6hjd:A, 6hjd:B, 6hjd:C, 6hjd:D, 6hjd:E, 6hjd:G, 6hjd:H, 6hjd:I, 6hjd:F, 6hmw:A, 6hmw:B, 6hmw:C, 6hmw:D, 6hmw:E, 6hmw:F, 6hmw:G, 6hmw:H, 6hmw:I, 6hmw:J, 6hmy:A, 6hmy:B, 6hmy:C, 6hmy:D, 6hmy:E, 6hmy:F, 6hmy:G, 6hmy:H, 6hmy:I, 6hmy:J, 1jr0:D, 1jr0:E, 1jr0:F, 1jr0:G, 1jr0:H, 1llr:D, 1llr:E, 1llr:F, 1llr:G, 1llr:H, 7lvb:D, 7lvb:E, 7lvb:G, 7lvb:H, 7lvb:A, 7lvb:B, 7lvb:C, 7lvb:I, 7lvb:J, 5lzg:A, 5lzg:B, 5lzg:C, 5lzg:D, 5lzg:E, 5lzh:A, 5lzh:B, 5lzh:C, 5lzh:D, 5lzh:E, 5lzj:C, 5lzj:D, 1md2:D, 1md2:E, 1md2:F, 8oxs:D, 8oxs:E, 8oxs:F, 8oxs:G, 8oxs:H, 8oxs:C, 8oxs:I, 8oxs:K, 8oxs:L, 1pzj:D, 1pzj:E, 1pzj:F, 1pzj:G, 1pzj:H, 1pzk:D, 1pzk:E, 1pzk:F, 1pzk:G, 1pzk:H, 8qre:D, 8qre:E, 8qre:F, 8qre:G, 8qre:H, 8qre:C, 8qre:I, 8qre:J, 8qre:K, 8qre:L, 1rcv:D, 1rcv:E, 1rcv:F, 1rcv:G, 1rcv:H, 1rd9:D, 1rd9:E, 1rd9:F, 1rd9:G, 1rd9:H, 1rdp:D, 1rdp:E, 1rdp:F, 1rdp:G, 1rdp:H, 1rf2:D, 1rf2:E, 1rf2:F, 1rf2:G, 1rf2:H, 1s5d:D, 1s5d:E, 1s5d:F, 1s5d:G, 1s5d:H, 1s5e:D, 1s5e:J, 1s5f:D, 1s5f:E, 1s5f:F, 1s5f:G, 1s5f:H
10 1fv5:A 36 21 0.0232 0.3333 0.5714 6.4 2l6z:B, 1y0j:B
11 5hwe:A 370 35 0.0271 0.0378 0.4000 8.8 5hxu:A, 5hxu:B, 5hxz:A, 5hxz:D, 5hy1:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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