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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RPNIILFMVDDMGWQDTSLPFWTQKTHYNEVYETPNMERLAKQGVMFTQAYASSICSPTRCSLITGTNAARHRVTNWTYP
KGQQTDRPSDVFNVADWNVNGVCQVPNIDHTFQATSLAEILKDNGYHTIHCGKAHFGAVNTPGESPYHMGFEVNIAGHAG
GGLASYLGENNYGNRTDGKPNPWFAVPGLDKYWGTDTFVSEALTLEAIKALNHAKEYNQPFFLYMAHYAIHVPIDKDKRF
YQKYIDKGLTPKEAAYAALIEGMDKSLGDLMDWLDKNGEADNTIVIFMSDNGGLSSEPGWRDGKLHTQNSPLNSGKGSAY
EGGVREPMIVRWPGVVKPDTKCDKYLIIEDFYPSILEMAQVKHYKTVQPIDGISFIPLLKQTGDPSKGRSLYWNFPNHWG
NDGPGIGPTCTVRKGDWKLIYYYENGKKELFNIPQDIGEKNNLAAQHPDIVKHLSKDLGNYLRKVGGQRPSFKATGKPCP
WPDEI

The query sequence (length=485) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6uss:A 485 485 1.0000 1.0000 1.0000 0.0 6uss:B
2 7oza:CCC 488 485 0.7876 0.7828 0.7876 0.0 7oza:AAA
3 7oz9:BBB 483 507 0.4247 0.4265 0.4063 4.08e-110 7oz9:AAA
4 6ust:C 464 505 0.3505 0.3664 0.3366 6.98e-78 6ust:A, 6ust:B, 6ust:D
5 7stt:A 445 499 0.3278 0.3573 0.3186 3.65e-61 7stu:A, 7stv:A
6 6psm:C 448 463 0.2804 0.3036 0.2937 1.31e-51 6prm:A, 6prm:B, 6prm:C, 6prm:D, 6psm:A, 6psm:B, 6psm:D, 6psm:E, 6psm:F, 6pso:B, 6pso:A
7 7ana:AAA 475 494 0.3010 0.3074 0.2955 4.07e-43 7ana:BBB, 7anb:AAA, 7anb:BBB
8 6b0j:A 452 468 0.2680 0.2876 0.2778 3.28e-42 6b0j:B, 6b0j:C, 6b0k:A, 6b0k:B, 6b0k:C, 6b1v:A, 6b1v:B, 6b1v:C, 6bia:A, 6bia:B, 6bia:C
9 7an1:AAA 483 495 0.2990 0.3002 0.2929 2.20e-40 7oqd:AAA
10 7all:AAA 498 514 0.2907 0.2831 0.2743 1.22e-38
11 7oze:AAA 487 528 0.2990 0.2977 0.2746 4.92e-34 7oze:EEE, 7oze:FFF, 7oze:GGG
12 4fdi:A 494 495 0.2763 0.2713 0.2707 1.04e-30 4fdi:B, 4fdj:A, 4fdj:B
13 4cys:A 534 567 0.2804 0.2547 0.2399 1.42e-30 5aj9:A, 5aj9:B, 4cxk:A, 4cxk:B, 4cxs:A, 4cxs:B, 4cxu:A, 4cxu:B, 4cyr:A, 4cyr:B, 4cys:B, 1hdh:A, 1hdh:B
14 6s20:C 480 526 0.3010 0.3042 0.2776 1.71e-29
15 7p26:AAA 484 506 0.2784 0.2789 0.2668 2.21e-28
16 1fsu:A 475 524 0.2619 0.2674 0.2424 8.15e-28
17 1n2l:A 483 489 0.2536 0.2547 0.2515 7.93e-27 1auk:A, 1e1z:P, 1e2s:P, 1e33:P, 1e3c:P, 1n2k:A
18 7aj0:A 501 384 0.1938 0.1876 0.2448 9.14e-24 7aj0:B, 7aj0:C, 7aj0:D, 7aj0:E, 7aj0:F
19 7ozc:AAA 485 524 0.2577 0.2577 0.2385 5.20e-21
20 6hr5:A 376 472 0.2474 0.3191 0.2542 9.84e-21
21 7oz8:AAA 474 513 0.2371 0.2426 0.2242 7.56e-19
22 8di0:B 426 393 0.2000 0.2277 0.2468 1.86e-17
23 6j66:B 476 400 0.2041 0.2080 0.2475 7.61e-17 6j66:A
24 8eg3:A 554 195 0.1134 0.0993 0.2821 3.55e-16 1p49:A
25 8eg3:A 554 138 0.0969 0.0848 0.3406 1.35e-09 1p49:A
26 5g2v:A 494 200 0.1175 0.1154 0.2850 5.94e-16
27 5g2v:A 494 88 0.0598 0.0587 0.3295 2.78e-05
28 7p24:AAA 494 192 0.1113 0.1093 0.2812 3.43e-14
29 7p24:AAA 494 231 0.1175 0.1154 0.2468 1.60e-09
30 2vqr:A 512 527 0.2371 0.2246 0.2182 1.32e-13
31 4uph:A 504 442 0.2165 0.2083 0.2376 4.39e-12 4uph:B, 4uph:C, 4uph:D
32 6s21:A 486 517 0.2309 0.2305 0.2166 1.30e-11 6s21:B, 6s21:C
33 6hhm:A 459 468 0.2186 0.2309 0.2265 1.81e-11
34 7ebp:A 526 190 0.1010 0.0932 0.2579 6.23e-11 7ebp:B, 7ebq:A
35 7ebp:A 526 233 0.1216 0.1122 0.2532 4.83e-05 7ebp:B, 7ebq:A
36 2w8s:B 513 466 0.2268 0.2144 0.2361 6.72e-11 2w8s:A, 2w8s:C, 2w8s:D
37 7pth:A 517 505 0.2268 0.2128 0.2178 1.92e-10 6fny:A, 6fny:B, 6fny:C, 6fny:D, 6fny:E, 6fny:F, 6fny:G, 6fny:H, 6g5z:A, 6g5z:B, 6g5z:C, 6g5z:D, 6g60:A, 6g60:B, 6g60:C, 6g60:D, 7pth:B, 7pth:C, 7pth:D, 7ptj:A, 7ptj:B, 7ptj:C, 7ptj:D
38 9fvt:A 519 158 0.0948 0.0886 0.2911 1.17e-09 9fvt:B, 9fvt:C, 9fvt:D
39 9fvt:A 519 147 0.0845 0.0790 0.2789 8.21e-07 9fvt:B, 9fvt:C, 9fvt:D
40 5fql:A 507 530 0.2474 0.2367 0.2264 4.36e-09 6ioz:A
41 7sno:A 506 254 0.1320 0.1265 0.2520 2.07e-08
42 7sno:A 506 256 0.1216 0.1166 0.2305 1.02e-04
43 7lj2:A 507 268 0.1381 0.1321 0.2500 5.37e-08 7lha:A, 7lha:B, 7lj2:B
44 7lj2:A 507 227 0.1134 0.1085 0.2423 2.02e-06 7lha:A, 7lha:B, 7lj2:B
45 6pt4:B 473 491 0.2165 0.2220 0.2138 3.18e-07 6pt4:A, 6pt6:B, 6pt6:A, 6pt9:A, 6pt9:B, 6ptk:A, 6ptk:B, 6ptk:C, 6ptk:D
46 4upl:A 555 236 0.1052 0.0919 0.2161 6.01e-07 4upl:C
47 4upl:A 555 71 0.0536 0.0468 0.3662 0.002 4upl:C
48 3b5q:B 467 232 0.1113 0.1156 0.2328 2.70e-05 3b5q:A, 5g2t:A, 5g2t:B, 5g2t:C, 5g2t:D, 5g2u:A
49 4upi:A 548 79 0.0557 0.0493 0.3418 0.001
50 4upi:A 548 128 0.0619 0.0547 0.2344 0.055
51 4miv:A 484 135 0.0742 0.0744 0.2667 0.002 4mhx:A, 4mhx:B, 4miv:B, 4miv:C, 4miv:D, 4miv:E, 4miv:F, 4miv:G, 4miv:H
52 4uop:B 409 168 0.0763 0.0905 0.2202 0.010 4uop:A
53 4uor:A 418 123 0.0577 0.0670 0.2276 0.28 4uoo:A, 4uoo:B, 4uoo:C, 4uoo:D, 4uoo:E, 4uor:B, 4uor:C, 4uor:D, 4uor:E, 4uor:F, 4uor:G, 4uor:H, 4uor:I, 4uor:J, 4uor:K
54 8g40:C 128 16 0.0186 0.0703 0.5625 4.0
55 4ib2:A 247 68 0.0495 0.0972 0.3529 6.2 4ib2:B
56 6v8q:A 569 80 0.0392 0.0334 0.2375 7.5 6v8q:B, 6vat:A, 6vat:B, 6vat:C, 6vc7:A, 6vc7:B, 6vc7:C, 6vc7:D, 6vc7:E, 6vc7:F, 6vdf:A, 6vdf:C, 6vdf:D
57 5zbh:A 461 63 0.0330 0.0347 0.2540 8.7
58 4a2e:A 496 85 0.0474 0.0464 0.2706 8.7 4a2d:A, 4a2f:A, 4a2g:A, 4a2h:A, 5a7e:A, 5anh:A, 5anh:B, 5anh:C, 6h5y:A, 6h5y:B, 2hrg:A, 2hrh:A, 4jhu:A, 4jhv:A
59 7zqy:B 177 36 0.0330 0.0904 0.4444 9.4 7zqy:A, 7zqy:C, 7zqy:D
60 2w5q:A 424 88 0.0412 0.0472 0.2273 9.4 2w5r:A, 2w5s:A, 2w5t:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218