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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
REALQNAVMFDKETMDKLMKEVPKYKVITPSIISDRLKISVALAGKGLQHLCRQGLIRLVSCSSKFRVYTRAA

The query sequence (length=73) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4v8m:AU 85 73 1.0000 0.8588 1.0000 4.63e-50 8ova:AU, 8ove:AU
2 7ase:a 70 69 0.8356 0.8714 0.8841 2.21e-41 5opt:a
3 8rxh:Sa 105 71 0.7808 0.5429 0.8028 2.44e-37 8a3w:Sa, 8a98:Sa, 6az1:a, 8ovj:Sa, 8rxx:Sa
4 7qiy:P 75 72 0.5342 0.5200 0.5417 9.60e-24 8auv:I, 8b2l:I1, 7qiz:ZA
5 8ip8:ta 77 73 0.5068 0.4805 0.5068 9.48e-23 8ip9:ta, 8ipa:ta, 8ipb:ta, 8jiw:BZ, 8r57:Z
6 6zj3:Sa 78 72 0.5479 0.5128 0.5556 2.24e-21
7 4v3p:SV 100 71 0.5068 0.3700 0.5211 5.57e-21 4v7e:BZ
8 5aj0:BZ 86 71 0.5342 0.4535 0.5493 9.12e-21 7a01:M3, 7a09:P, 5a2q:Z, 9bdl:AS25, 9bdn:AS25, 9bdp:AS25, 8bhf:a3, 9bkd:e, 9bln:e, 8btk:Ay, 7cpu:SZ, 7cpv:SZ, 4d5l:Z, 4d61:Z, 6d90:aa, 6d9j:aa, 9f1b:Ay, 9f1c:Ay, 9f1d:Ay, 6fec:W, 5flx:Z, 6g18:Z, 6g4s:Z, 6g4w:Z, 6g51:Z, 6g53:Z, 6g5h:Z, 6g5i:Z, 8g5y:SZ, 8g5z:SZ, 8g60:SZ, 8g61:SZ, 8g6j:SZ, 8glp:SZ, 6gz3:BZ, 6gz4:BZ, 6gz5:BZ, 6hcf:a1, 6hcm:a1, 8ifd:3O, 8ife:3O, 6ip5:3O, 6ip6:3O, 6ip8:3O, 3j7p:SZ, 3j7r:SZ, 3jag:ZZ, 3jah:ZZ, 3jai:ZZ, 3jaj:SZ, 3jan:SZ, 8jdj:AL, 8jdk:AL, 8jdl:AL, 8jdm:AL, 7jqb:a, 7jqc:a, 5k0y:W, 8k2c:SZ, 7k5i:Z, 4kzx:Z, 4kzy:Z, 4kzz:Z, 5lks:SZ, 7ls1:R3, 7ls2:R3, 5lzs:ZZ, 5lzt:ZZ, 5lzu:ZZ, 5lzv:ZZ, 5lzw:ZZ, 5lzx:ZZ, 5lzy:ZZ, 5lzz:ZZ, 7mdz:ZZ, 6mtb:ZZ, 6mtc:ZZ, 6mtd:ZZ, 6mte:ZZ, 7nwg:a2, 7nwh:ZZ, 7nwi:ZZ, 7o7y:Ay, 7o7z:Ay, 7o80:Ay, 7o81:Ay, 5oa3:Z, 6ole:SZ, 6olf:SZ, 6olg:BZ, 6oli:SZ, 6olz:BZ, 6om0:SZ, 6om7:SZ, 7oya:Z2, 7oyb:Z2, 7oyc:Z2, 7oyd:ZZ, 8oz0:m, 8p03:n, 8p09:n, 8p2k:Ay, 6p4g:a, 6p4h:a, 6p5i:a, 6p5j:a, 6p5k:a, 6p5n:a, 8pj1:e, 8pj2:e, 8pj3:e, 8pj4:e, 8pj5:e, 8pj6:e, 8ppk:Z, 8ppl:AZ, 8q7z:Ay, 8q87:Ay, 7qgg:SZ, 8qoi:SZ, 7qp6:e, 7qp7:e, 7qvp:SZ, 7qvp:RZ, 6qzp:SZ, 7r4x:Z, 6r5q:OO, 6r6g:OO, 6r6p:OO, 6r7q:OO, 8scb:ZZ, 6sgc:a1, 7syg:a, 7syh:a, 7syi:a, 7syj:a, 7syk:a, 7syl:a, 7sym:a, 7syn:a, 7syo:a, 7syp:a, 7syq:a, 7syr:a, 7sys:a, 7syt:a, 7syu:a, 7syv:a, 7syw:a, 7syx:a, 5t2c:AR, 8t4s:Z, 7toq:AS25, 7tor:AS25, 7tql:a, 7ucj:ZZ, 7uck:ZZ, 4ug0:SZ, 4ujc:CZ, 4ujd:CZ, 4uje:BZ, 4v6x:AZ, 5vyc:Z1, 5vyc:Z2, 5vyc:Z5, 5vyc:Z3, 5vyc:Z4, 5vyc:Z6, 6w2s:a, 6w2t:i, 7wtt:Z, 7wtu:Z, 7wtv:Z, 7wtw:Z, 7wtx:Z, 7wtz:Z, 7wu0:Z, 6xa1:SZ, 7xnx:SZ, 7xny:SZ, 8xsx:SZ, 8xsy:SZ, 8xsz:SZ, 8xxl:SZ, 8xxm:SZ, 8xxn:SZ, 6y0g:SZ, 8y0w:SZ, 8y0x:SZ, 6y2l:SZ, 6y57:SZ, 6yal:n, 6yam:n, 6yan:h, 6ybs:e, 8yoo:SZ, 8yop:SZ, 6z6l:SZ, 6z6m:SZ, 6z6n:SZ, 7zjw:Sk, 7zjx:Sk, 6zlw:a, 6zm7:SZ, 6zme:SZ, 6zmi:SZ, 6zmo:SZ, 6zmt:a, 6zmw:e, 6zn5:a, 6zoj:Z, 6zol:Z, 6zon:P, 6zp4:P, 6zuo:Z, 6zv6:Z, 6zvh:Z, 6zvj:P, 6zvk:M3, 6zxd:Z, 6zxe:Z, 6zxf:Z, 6zxg:Z, 6zxh:Z
9 4v6w:AZ 74 73 0.5068 0.5000 0.5068 4.82e-19 6xu6:AZ, 6xu7:AZ, 6xu8:AZ
10 9bh5:AZ 71 71 0.4795 0.4930 0.4930 9.18e-18 9cai:AZ
11 7rr5:SZ 100 68 0.4247 0.3100 0.4559 8.78e-17 7a1g:L, 7b7d:K, 8bn3:D5, 8bqd:K, 8bqx:K, 8c00:K, 8c01:K, 8cah:L, 8cas:M, 8cbj:Z, 8ccs:1, 8cdl:1, 8cdr:1, 8ceh:1, 8cf5:1, 8cg8:1, 8cgn:1, 8civ:1, 8cku:1, 8cmj:1, 5dat:D5, 5dat:d5, 5dc3:D5, 5dc3:d5, 5dge:D5, 5dge:d5, 5dgf:D5, 5dgf:d5, 5dgv:D5, 5dgv:d5, 6eml:K, 8eub:BZ, 8evp:BZ, 8evq:BZ, 8evr:BZ, 8evs:BZ, 8evt:BZ, 8ewb:BZ, 8ewc:BZ, 6fai:Z, 5fci:D5, 5fci:d5, 5fcj:D5, 5fcj:d5, 6gq1:AP, 6gqb:AP, 6gqv:AP, 6hhq:a, 6hhq:d5, 5i4l:D5, 5i4l:d5, 6i7o:K, 6i7o:Kb, 3j6x:25, 3j6y:25, 3j77:25, 3j78:25, 5juo:WB, 5jup:WB, 5jus:WB, 5jut:WB, 5juu:WB, 8k2d:SZ, 8k82:SZ, 5lyb:D5, 5lyb:d5, 5m1j:Z2, 5mc6:K, 5mei:d5, 5mei:a, 7mpi:BZ, 7mpj:BZ, 7n8b:BZ, 5ndg:D5, 5ndg:d5, 5ndv:D5, 5ndv:d5, 5ndw:D5, 5ndw:d5, 7nrc:SK, 7nrd:SK, 5obm:D5, 5obm:d5, 5on6:d5, 5on6:a, 7osa:eS25, 7osm:eS25, 6q8y:K, 6rbd:Z, 6rbe:Z, 6s47:Ba, 6snt:Z, 6sv4:K, 6sv4:Kb, 6sv4:Kc, 6t4q:SZ, 6t7i:SZ, 6t7t:SZ, 6t83:Zb, 6t83:0, 5tbw:a, 5tbw:d5, 6tb3:K, 5tga:D5, 5tga:d5, 5tgm:D5, 5tgm:d5, 6tnu:K, 4u3m:D5, 4u3m:d5, 4u3n:D5, 4u3n:d5, 4u3u:D5, 4u3u:d5, 4u4n:D5, 4u4n:d5, 4u4o:D5, 4u4o:d5, 4u4q:D5, 4u4q:d5, 4u4r:D5, 4u4r:d5, 4u4u:D5, 4u4u:d5, 4u4y:D5, 4u4y:d5, 4u4z:D5, 4u4z:d5, 4u50:D5, 4u50:d5, 4u51:D5, 4u51:d5, 4u52:D5, 4u52:d5, 4u53:D5, 4u53:d5, 4u55:D5, 4u55:d5, 4u56:D5, 4u56:d5, 4u6f:D5, 4u6f:d5, 4uer:8, 4v6i:AV, 4v88:AZ, 4v88:CZ, 4v8y:AZ, 4v8z:AZ, 4v92:BZ, 6wdr:Z, 6woo:ZZ, 6xiq:AP, 6xir:AP, 8y0u:SZ, 6y7c:Z, 6z6j:SZ, 6z6k:SZ, 6zce:a, 7zpq:AZ, 6zqg:DZ, 7zrs:AZ, 6zu9:M, 7zuw:AZ, 7zux:DZ, 6zvi:J, 7zw0:sK
12 6fyx:Z 78 72 0.3836 0.3590 0.3889 7.21e-15 6fyy:Z, 6gsm:Z, 6gsn:Z, 8i7j:Z, 5it7:Z, 5it9:Z, 3j80:Z, 3j81:Z, 3jam:Z, 3jap:Z, 8rw1:Z, 8s8d:Z, 8s8e:Z, 8s8f:Z, 8s8g:Z, 8s8h:Z, 8s8i:Z, 8s8j:Z, 6uz7:Z
13 7r81:a2 71 68 0.4247 0.4366 0.4559 4.16e-14 7olc:SZ, 7old:SZ, 8oo0:SZ, 7z3n:SZ, 7z3o:SZ
14 5xxu:Z 71 68 0.3699 0.3803 0.3971 7.84e-14
15 8c3a:b 72 68 0.3973 0.4028 0.4265 9.50e-13 8c3a:DM, 8cq7:b, 8cq7:DM, 8cqw:b, 8cqw:DM, 8cre:b, 8cre:DM, 8oeq:b, 8oeq:DM, 7pzy:a, 7q08:a, 7q0f:a, 7q0p:a, 7q0r:a
16 6zu5:SZ0 72 71 0.2877 0.2917 0.2958 2.52e-09
17 8br8:Sc 75 59 0.2740 0.2667 0.3390 6.58e-06 8brm:Sc, 8bsi:Sc, 8bsj:Sc, 8btd:Sc, 8btr:Sc, 8fvy:Z, 8g4s:Z, 7pwf:Z
18 7qep:D5 87 69 0.2466 0.2069 0.2609 2.94e-05
19 5xyi:Z 73 68 0.3151 0.3151 0.3382 6.69e-05
20 7qca:SZ0 76 59 0.1918 0.1842 0.2373 0.008
21 7ml7:A 1216 32 0.2192 0.0132 0.5000 0.013
22 8y9b:B 1607 32 0.2192 0.0100 0.5000 0.013
23 8qeo:A 2146 32 0.2192 0.0075 0.5000 0.013
24 8qen:A 2363 32 0.2192 0.0068 0.5000 0.013 9bja:A, 9bja:B, 2bvl:A, 2bvm:A, 6c0b:A, 7lou:A, 7lou:B, 7lov:A, 7lov:B, 3pa8:A, 3pa8:B, 3pee:B, 3pee:A, 7s0y:A, 5uqm:A, 5uqn:A, 5uqt:A, 5uqt:B
25 8y9c:B 1609 32 0.1918 0.0087 0.4375 0.26
26 3j7a:2 41 28 0.1370 0.2439 0.3571 0.70 3jbn:2, 3jbo:2, 3jbp:2, 6okk:b, 8tpu:S2
27 4v5o:A8 93 70 0.2192 0.1720 0.2286 0.82 4bts:A8, 4bts:B8, 4bts:C8, 4bts:D8, 4v5o:B8
28 6oq5:A 2346 32 0.1781 0.0055 0.4062 0.86 6oq7:A, 7s0z:B, 7s0z:A
29 4eqb:A 323 54 0.2329 0.0526 0.3148 0.98 4eqb:B
30 6jbx:A 146 41 0.1781 0.0890 0.3171 3.0 6jbx:B
31 8r0s:A 470 21 0.1507 0.0234 0.5238 4.4
32 1cg0:A 431 25 0.1507 0.0255 0.4400 4.5 1cg1:A, 1cg3:A, 1cg4:A, 1ch8:A, 1cib:A, 2gcq:A, 1gim:A, 1gin:A, 1hon:A, 1hoo:A, 1juy:A, 1kjx:A, 1kkb:A, 1kkf:A, 1ksz:A, 1nht:A, 1qf4:A, 1qf5:A, 1son:A, 1soo:A
33 3mcx:A 459 38 0.1781 0.0283 0.3421 8.6

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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