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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QRWRSDGRCGPNYPAPDANPGECNPHAVDHCCSEWGWCGRETSHCTCSSCVDYSAGSSGTCPRIVSKSEWGSRATNYNVF
LSLPVPKVVIHHSAGATCSTQSSCSLQVRNIQNYHMDGRGYSDIGYNFLVGNDGNVYEGRGWDRRGAHALNVNTESIGIC
FMGDFTSQKPTASAIAAAKSLISCGVSLGKIRSGYSLYGHRDVGSTACPGNLLYDDIKSWGRYV

The query sequence (length=224) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4z8i:A 224 224 1.0000 1.0000 1.0000 4.35e-168
2 3cg9:A 171 165 0.3482 0.4561 0.4727 1.86e-50 6a89:B, 6a89:A, 6a89:D, 3cg9:B, 3cxa:A, 3cxa:B, 7dy5:C, 5e0b:C, 4fnn:A, 4fnn:B, 4fnn:D, 4gf9:D, 4gf9:C, 3ng4:C, 3ng4:D, 3nno:D, 3nw3:D, 3o4k:A, 3o4k:C, 3o4k:D, 3ogx:C, 3ogx:A, 4opp:A, 4opp:B, 4opp:D, 4opp:C, 4orv:D, 4oug:C, 4oug:D, 4q8s:A, 4q8s:C, 4q8s:D, 4q9e:D, 3qv4:C, 3rt4:C, 3rt4:D, 3t2v:B, 3t2v:D, 3t39:D, 3tru:D, 3usx:B, 7xfw:C, 7xfx:C, 7xfy:C, 7xfy:D, 7xu8:A, 7xu8:B
3 2aph:A 165 164 0.3170 0.4303 0.4329 1.24e-46 2aph:B, 1sk4:A, 1twq:A
4 2f2l:X 166 158 0.3259 0.4398 0.4620 5.58e-46
5 2eax:C 164 163 0.3125 0.4268 0.4294 5.89e-42
6 1oht:A 173 162 0.2991 0.3873 0.4136 3.28e-41 7nsx:AAA, 7nsz:AAA, 7nt0:AAA, 7nt0:BBB
7 2xz4:A 165 161 0.2812 0.3818 0.3913 4.31e-41
8 2cb3:C 173 161 0.2902 0.3757 0.4037 2.15e-38 2cb3:A, 2cb3:B, 2cb3:D
9 2f2l:A 167 162 0.2455 0.3293 0.3395 1.61e-28
10 6srt:A 152 160 0.2054 0.3026 0.2875 1.28e-13 6ssc:A
11 1lba:A 146 124 0.1830 0.2808 0.3306 5.68e-13
12 6fhg:A 156 154 0.1964 0.2821 0.2857 2.48e-12 6fhg:B
13 6su5:A 154 134 0.1741 0.2532 0.2910 8.15e-11
14 7f5i:A 153 102 0.1652 0.2418 0.3627 7.53e-10
15 3vth:A 753 67 0.0982 0.0292 0.3284 1.3 3vth:B, 3vti:A, 3vti:B
16 6ygd:B 720 93 0.1161 0.0361 0.2796 1.8
17 4wp4:A 43 16 0.0402 0.2093 0.5625 2.3
18 6lnr:A 292 21 0.0446 0.0342 0.4762 6.5
19 6sto:A 165 137 0.1652 0.2242 0.2701 7.2 6sto:B, 6stp:A, 6stp:B
20 4o5o:B 261 33 0.0580 0.0498 0.3939 7.5 4o5o:A
21 7aqr:P 332 40 0.0759 0.0512 0.4250 8.5 7a23:T, 7a24:T, 7ar7:P, 7ar8:P, 7arb:P, 8bee:P, 8bpx:P, 8bq5:P, 8bq6:P

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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