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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QKTLEVWIMPNSPQPAEDFKALVAPFEKAHGVEVKVTVLDWGVAWTKITTAATSGVGPDLTQLGTTWVGAISAMGVLEPV
DDVLEALGGEKAYLPAVWRTTRLEGARQATAVPWFSELRAFYYRTDALKAAGVNPAEMFASWQGFEAGLARLKASSFRDP
ETKAPLAPLCTPGKNSWDVLHNAAPWIWGAGGEIVRQAGGRWQSALNSPESLEGLYFFLSLAQKGYVPAESLEKNTAQIE
ADFQAGKCAVFASGPWMIQRAQVPEAKGGFAERTAAKNLGVAPYPAGPKGRYTFFGGSNLALFNFSKNKPLAKELLKYLG
GPEAQVRYAQMTGMLPALRSAWSDPSFQQNPLLRTFIQAAQFGRTYPSLAGWGGVENLAVQHLGMAWDLVAQGRLTREAL
KDLMDKASAAINQALRHH

The query sequence (length=418) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7c6g:A 420 418 0.9856 0.9810 0.9856 0.0 7c63:A, 7c64:A, 7c64:B, 7c66:A, 7c66:B, 7c67:A, 7c67:B, 7c68:A, 7c68:B, 7c69:A, 7c69:B, 7c6f:A, 7c6g:B, 7c6h:A, 7c6h:B, 7c6i:A, 7c6i:B, 7c6j:A, 7c6j:B, 7c6k:A, 7c6l:A, 7c6l:B, 7c6m:A, 7c6n:A, 7c6n:B, 7c6r:A, 7c6t:A, 7c6v:A, 7c6v:B, 7c6v:C, 7c6w:A, 7c6z:A, 7c6z:B, 7c70:A, 7c70:B, 7c71:A
2 7x0l:A 409 419 0.3876 0.3961 0.3866 2.73e-94 7x0j:A, 7x0j:B, 7x0k:A, 7x0k:B, 7x0l:B, 7x0m:A, 7x0m:B, 7x0n:A, 7x0n:B
3 5ysd:B 389 425 0.2656 0.2853 0.2612 6.38e-33 5ysb:A, 5ysb:B, 5ysd:A, 5yse:A, 5yse:B, 5ysf:A, 5ysf:B
4 3jzj:A 388 356 0.2344 0.2526 0.2753 1.34e-23 3k00:A, 3k02:A
5 5ci5:A 393 337 0.1986 0.2112 0.2463 1.06e-22 5ci5:B
6 1eu8:A 407 363 0.2129 0.2187 0.2452 1.63e-18
7 8art:B 393 346 0.2081 0.2214 0.2514 4.68e-16 8art:A
8 6dtq:A 391 376 0.2105 0.2251 0.2340 9.62e-15 6dtq:B, 6dtq:C, 6dtq:D
9 2zyo:A 385 199 0.1483 0.1610 0.3116 8.12e-14 2zyk:A, 2zyk:B, 2zyk:C, 2zyk:D, 2zym:A, 2zyn:A
10 1elj:A 380 346 0.2081 0.2289 0.2514 8.59e-14
11 6dts:A 379 433 0.2368 0.2612 0.2286 2.24e-13 8dhd:A, 6dts:B, 2fnc:A
12 4hw8:A 376 407 0.2225 0.2473 0.2285 2.83e-12 4hw8:B
13 6dtu:A 375 422 0.2297 0.2560 0.2275 6.77e-12 6dtu:B, 2gha:A, 2gha:B
14 5tu0:A 385 372 0.2225 0.2416 0.2500 8.54e-12
15 7ehp:A 397 398 0.2440 0.2569 0.2563 2.18e-11 7ehp:B
16 7c0k:B 397 374 0.2201 0.2317 0.2460 6.05e-11 7c0f:A, 7c0f:B, 7c0k:A, 7c0l:A, 7c0l:B, 7c0o:A, 7c0o:B, 7c0r:A, 7c0r:B, 7c0s:A, 7c0s:B, 7c0t:A, 7c0t:B, 7c0u:A, 7c0u:B, 7c0v:A, 7c0v:B, 7c0w:A, 7c0w:B, 7c0x:A, 7c0x:B, 7c0y:A, 7c0y:B, 7c0z:A, 7c0z:B, 7c14:A, 7c14:B, 7c15:A, 7c15:B, 7c16:A, 7c16:B, 7c19:A, 7c19:B
17 1urg:A 373 377 0.2129 0.2386 0.2361 6.40e-10 1urd:A, 1urd:B, 1urs:A, 1urs:B
18 4qrz:A 383 381 0.1842 0.2010 0.2021 3.70e-08 4qsc:A, 4qsd:A
19 7bvt:A 391 416 0.2201 0.2353 0.2212 8.10e-08
20 4aq4:A 418 313 0.1842 0.1842 0.2460 2.89e-07 6x84:B
21 4r9f:A 402 371 0.1890 0.1965 0.2129 4.97e-07 4r9g:A, 4r9g:B
22 2gh9:A 378 395 0.2249 0.2487 0.2380 7.01e-07
23 7v09:A 403 207 0.1364 0.1414 0.2754 2.44e-06 7v09:B
24 5mk9:A 378 360 0.1842 0.2037 0.2139 2.86e-06 5m28:A, 5mka:A, 5mtt:A, 5mtu:A
25 2xd3:A 375 354 0.2081 0.2320 0.2458 3.42e-06
26 4r2f:A 394 399 0.2105 0.2234 0.2206 4.00e-06
27 7qhv:AAA 390 256 0.1435 0.1538 0.2344 2.74e-05 7ofy:A, 7ofy:B, 7qhv:BBB, 8s5b:A, 7yzs:AAA, 7yzu:A
28 7ehq:A 406 224 0.1268 0.1305 0.2366 3.35e-05 7ehu:A
29 6jam:A 406 420 0.2344 0.2414 0.2333 7.27e-05 6j9w:A, 6j9y:A, 6jad:A, 6jag:A, 6jah:A, 6jai:A, 6jan:A, 6jao:A, 6jap:A, 6jaq:A, 6jar:A, 6jaz:A, 6jb0:A, 6jb4:A, 6jba:A, 6jbb:A, 6jbe:A
30 4rya:A 417 231 0.1388 0.1391 0.2511 1.15e-04
31 7caf:E 443 77 0.0742 0.0700 0.4026 1.21e-04 8hpl:E, 8hpm:E, 8hpn:E, 8hpr:E
32 8ja7:E 443 83 0.0718 0.0677 0.3614 2.15e-04 8ja8:A, 8ja9:A, 8jaa:A, 8jab:A, 8jac:A, 8jad:A, 7wda:A, 7wda:B, 7wda:C, 7wda:D
33 6lce:A 407 342 0.1627 0.1671 0.1988 2.49e-04 6lcf:A, 6lcf:B
34 6rjy:A 415 379 0.1914 0.1928 0.2111 6.66e-04 6rkh:A, 6rkj:A, 6rkl:A, 6rkx:A, 6rl1:A, 6rl2:A
35 6r1b:B 395 352 0.2010 0.2127 0.2386 0.002 6r1b:A, 6r1b:C, 6r1b:D
36 5f7v:A 388 261 0.1411 0.1521 0.2261 0.002
37 6ffl:A 383 163 0.1005 0.1097 0.2577 0.004
38 6ffl:A 383 60 0.0478 0.0522 0.3333 0.091
39 7ape:A 435 74 0.0646 0.0621 0.3649 0.052 7ape:B
40 8bfy:A 393 392 0.2201 0.2341 0.2347 0.22
41 2w7y:A 389 98 0.0718 0.0771 0.3061 0.41 2w7y:B
42 5mlt:A 454 308 0.1603 0.1476 0.2175 0.64 5swa:A, 5swa:B, 5swb:A, 5swb:C, 5swb:D, 5swb:G
43 4elq:A 310 127 0.0766 0.1032 0.2520 0.70 4elp:A, 4elp:B, 4elp:C, 4elp:D, 4elq:B, 4elr:A, 4elr:B, 3wae:A, 3wae:B
44 1si0:A 316 57 0.0431 0.0570 0.3158 1.2 1si1:A
45 5z6b:A 393 140 0.0694 0.0738 0.2071 1.8
46 3oo6:A 390 111 0.0670 0.0718 0.2523 2.2 3oo6:B
47 7vfq:C 397 64 0.0502 0.0529 0.3281 2.2 7vfq:A, 7vfq:B, 7vfq:D, 7vfr:A
48 6mvh:D 305 192 0.1148 0.1574 0.2500 2.3
49 6rxt:UA 839 30 0.0263 0.0131 0.3667 5.1 5oql:A, 6rxu:UA, 6rxv:UA, 6rxx:UA, 6rxy:UA, 6rxz:UA
50 2r7k:A 358 73 0.0455 0.0531 0.2603 6.7 2r7l:A, 2r7m:A, 2r7n:A
51 5ugr:A 323 35 0.0335 0.0433 0.4000 8.4
52 2cbn:A 306 51 0.0407 0.0556 0.3333 9.4

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218