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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PAGFTDYKVADITLAAWGRRELIIAESEMPALMGLRRKYAGQQPLKGAKILGCIHMTIQTGVLIETLVALGAEVRWSSCN
IFSTQDQAAAAIAAAGIPVFAWKGETEEEYEWCIEQTILKDGQPWDANMVLDDGGDLTEILHKKYPQMLERIHGITEETT
TGVHRLLDMLKNGTLKVPAINVNDSVTKSKNDNKYGCRHSLNDAIKRGTDHLLSGKQALVIGYGDVGKGSSQSLRQEGMI
VKVAEVDPICAMQACMDGFEVVSPYKNGINDGTEASIDAALLGKIDLIVTTTGNVNVCDANMLKALKKRAVVCNIGHFDN
EIDTAFMRKNWAWEEVKPQVHKIHRTGKDGFDAHNDDYLILLAEGRLVNLGNATGHPSRIMDGSFANQVLAQIHLFEQKY
ADLPAAEKAKRLSVEVLPKKLDEEVALEMVKGFGGVVTQLTPKQAEYIGVSVEGPFKPDTYRY

The query sequence (length=463) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8cfu:A 467 463 1.0000 0.9914 1.0000 0.0 8ajs:AAA, 8ajs:DDD, 8ajs:BBB, 8ajs:CCC, 8ajt:AAA, 8ajt:DDD, 8ajt:BBB, 8ajt:CCC, 8aju:AAA, 8aju:CCC, 8ajv:AAA, 8ajv:DDD, 8ajv:BBB, 8ajv:CCC, 8ajv:FFF, 8ajv:III, 8ajv:GGG, 8ajv:HHH, 8ajw:AAA, 8ajw:DDD, 8ajw:BBB, 8ajw:CCC, 8azf:A, 8azf:C, 8cfb:A, 8cfb:D, 8cfb:B, 8cfb:C, 8cfc:A, 8cfc:D, 8cfc:B, 8cfc:C, 8cfd:A, 8cfd:D, 8cfd:B, 8cfd:C, 8cfe:A, 8cfe:D, 8cfe:B, 8cfe:C, 8cfg:A, 8cfg:D, 8cfg:B, 8cfg:C, 8cfh:A, 8cfh:D, 8cfh:B, 8cfh:C, 8cfi:A, 8cfi:D, 8cfi:B, 8cfi:C, 8cfj:A, 8cfj:D, 8cfj:B, 8cfj:C, 8cfk:A, 8cfk:D, 8cfk:B, 8cfk:C, 8cfl:A, 8cfl:D, 8cfl:B, 8cfl:C, 8cfm:A, 8cfm:D, 8cfm:B, 8cfm:C, 8cfn:A, 8cfn:C, 8cfo:A, 8cfo:D, 8cfo:B, 8cfo:C, 8cfp:A, 8cfp:D, 8cfp:B, 8cfp:C, 8cfq:A, 8cfq:D, 8cfq:B, 8cfq:C, 8cfr:A, 8cfr:D, 8cfr:B, 8cfr:C, 8cfs:A, 8cfs:D, 8cfs:B, 8cfs:C, 8cft:A, 8cft:D, 8cft:B, 8cft:C, 8cfu:D, 8cfu:B, 8cfu:C, 8cfv:A, 8cfv:D, 8cfv:B, 8cfv:C, 8cfw:A, 8cfw:D, 8cfw:B, 8cfw:C, 8cfx:A, 8cfx:D, 8cfx:B, 8cfx:C, 8cfx:G, 8cfx:J, 8cfx:H, 8cfx:I, 8cfy:A, 8cfy:D, 8cfy:B, 8cfy:C, 8cfy:G, 8cfy:J, 8cfy:H, 8cfy:I, 8cfz:A, 8cfz:D, 8cfz:B, 8cfz:C, 8cfz:H, 8cfz:K, 8cfz:I, 8cfz:J, 8cg0:A, 8cg0:D, 8cg0:B, 8cg0:C, 8cg1:A, 8cg1:D, 8cg1:B, 8cg1:C, 8cg1:G, 8cg1:J, 8cg1:H, 8cg1:I, 8cg2:A, 8cg2:C, 6f3m:A, 6f3m:B, 6f3m:C, 6f3m:D, 6f3n:A, 6f3n:B, 6f3n:C, 6f3n:D, 6f3o:A, 6f3o:B, 6f3o:C, 6f3o:D, 6f3p:A, 6f3p:C, 6f3q:A, 6f3q:B, 6f3q:C, 6f3q:D, 7zd0:A, 7zd0:D, 7zd0:B, 7zd0:C, 7zd1:A, 7zd1:D, 7zd1:B, 7zd1:C, 7zd2:A, 7zd2:D, 7zd2:B, 7zd2:C, 7zd3:A, 7zd3:D, 7zd3:B, 7zd3:C, 7zd4:A, 7zd4:D, 7zd4:B, 7zd4:C
2 6aph:A 432 466 0.5659 0.6065 0.5622 1.56e-173
3 1a7a:A 431 462 0.5616 0.6032 0.5628 1.82e-165 1a7a:B, 5axa:A, 5axa:C, 5axb:A, 5axb:C, 5axc:A, 5axc:C, 5axd:A, 5axd:C, 1b3r:A, 1b3r:B, 1b3r:C, 1b3r:D, 8cod:A, 8cod:B, 1d4f:A, 1d4f:B, 1d4f:C, 1d4f:D, 2h5l:A, 2h5l:B, 2h5l:C, 2h5l:D, 2h5l:E, 2h5l:F, 2h5l:G, 2h5l:H, 1k0u:A, 1k0u:B, 1k0u:C, 1k0u:D, 1k0u:E, 1k0u:F, 1k0u:G, 1k0u:H, 1ky4:A, 1ky4:B, 1ky4:C, 1ky4:D, 1ky5:A, 1ky5:B, 1ky5:C, 1ky5:D, 1li4:A, 3nj4:A, 3nj4:B, 3nj4:C, 3nj4:D, 4pfj:A, 4pfj:B, 4pgf:A, 4pgf:B, 5w49:A, 5w49:B, 5w4b:A, 5w4b:B, 5w4b:C, 5w4b:D, 5w4b:E, 5w4b:F, 1xwf:A, 1xwf:B, 1xwf:C, 1xwf:D, 4yvf:A, 4yvf:B
4 3h9u:C 435 461 0.5508 0.5862 0.5531 1.02e-164 3h9u:A, 3h9u:B, 3h9u:D
5 6gbn:B 435 466 0.5378 0.5724 0.5343 4.33e-163 6gbn:A, 6gbn:C, 6gbn:D
6 3d64:A 462 494 0.5637 0.5649 0.5283 4.00e-159 3d64:B, 3glq:A, 3glq:B
7 3g1u:C 424 457 0.5248 0.5731 0.5317 5.79e-155 3g1u:A, 3g1u:B, 3g1u:D
8 5m5k:C 471 498 0.5572 0.5478 0.5181 7.46e-153 6exi:A, 6exi:B, 6exi:C, 6exi:D, 4lvc:A, 4lvc:B, 4lvc:C, 4lvc:D, 5m5k:A, 5m5k:B, 5m5k:D, 5m65:A, 5m65:B, 5m66:A, 5m66:B, 5m66:C, 5m66:D, 5m67:A, 5m67:B, 5m67:C, 5m67:D
9 6uk3:A 475 504 0.5486 0.5347 0.5040 2.00e-151 6uk3:C, 6uk3:B, 6uk3:D
10 3ce6:A 486 509 0.5378 0.5123 0.4892 5.36e-151 3ce6:B, 3ce6:C, 3ce6:D, 3dhy:A, 3dhy:B, 3dhy:C, 3dhy:D, 2ziz:A, 2ziz:B, 2ziz:C, 2ziz:D, 2zj0:A, 2zj0:B, 2zj0:C, 2zj0:D, 2zj1:A, 2zj1:B, 2zj1:C, 2zj1:D
11 3n58:B 461 492 0.5486 0.5510 0.5163 9.23e-150 3n58:A, 3n58:C, 3n58:D
12 3gvp:A 433 459 0.4708 0.5035 0.4749 1.46e-141 3gvp:B, 3gvp:C, 3gvp:D, 3mtg:A, 3mtg:B
13 3ond:B 488 502 0.5140 0.4877 0.4741 9.25e-139 3ond:A, 3one:A, 3one:B, 3onf:A, 3onf:B
14 5v96:A 467 496 0.4946 0.4904 0.4617 1.18e-134 5v96:B, 5v96:C, 5v96:D
15 1v8b:A 476 501 0.4730 0.4601 0.4371 1.83e-128 1v8b:B, 1v8b:C, 1v8b:D
16 5jpi:A 496 518 0.4644 0.4335 0.4151 9.67e-118 5hm8:A, 5hm8:B, 5hm8:C, 5hm8:D, 5hm8:E, 5hm8:F, 5hm8:G, 5hm8:H, 5jpi:B, 5jpi:C, 5jpi:D, 5jxw:A, 5jxw:B, 5jxw:C, 5jxw:D, 5t8k:A, 5t8k:C, 5t8k:B, 5t8k:D, 5tj9:A, 5tj9:B, 5tj9:C, 5tj9:D, 5tls:A, 5tls:B, 5tls:C, 5tls:D, 5utu:A, 5utu:B, 5utu:C, 5utu:D, 5utu:E, 5utu:F, 5utu:G, 5utu:H
17 7r39:A 412 443 0.3758 0.4223 0.3928 8.28e-89 7r39:B, 7r39:C, 7r39:D, 7r39:E, 7r39:F, 7r39:G, 7r39:H
18 8qno:A 421 443 0.3650 0.4014 0.3815 4.33e-82 8qno:B, 7r37:A, 7r37:B, 7r38:A, 7r38:B
19 7o5l:A 417 443 0.3672 0.4077 0.3837 4.75e-78 7o5l:C, 7o5m:A, 7o5m:C, 7zd7:A, 7zd7:C, 7zd8:A, 7zd8:C, 7zd9:A, 7zd9:C
20 7r3a:A 411 442 0.3456 0.3893 0.3620 1.65e-77 7r3a:B, 7r3a:C, 7r3a:D, 7r3a:E, 7r3a:F, 7r3a:G, 7r3a:H
21 3x2f:A 406 421 0.3348 0.3818 0.3682 1.48e-74 5tov:B, 5tow:B, 3x2e:A, 3x2e:B, 3x2e:C, 3x2e:D, 3x2f:B
22 8ep7:C 328 53 0.0540 0.0762 0.4717 0.011 8ep7:A, 8ep7:B
23 5dbh:X 312 113 0.0670 0.0994 0.2743 0.97 6aif:A, 5dbe:X, 7djq:A, 3iqg:X, 3iqh:X, 3iqi:X, 4li3:X, 4nu8:X, 4ore:X, 1y7l:A, 7yod:A, 7yoh:A, 7yoi:A, 7yol:A, 7yom:A, 4zu1:X, 4zu6:X
24 7x4n:E 332 40 0.0302 0.0422 0.3500 1.1
25 6jcz:C 331 49 0.0410 0.0574 0.3878 1.4 6jcw:A, 6jcw:B, 6jcw:C, 6jcw:D, 6jcw:E, 6jcw:F, 6jcw:G, 6jcw:H, 6jcw:I, 6jcw:J, 6jcw:K, 6jcw:L, 6jcz:A, 6jcz:B, 6jcz:D, 6jcz:E, 6jcz:F, 6jcz:G, 6jcz:H, 6jcz:I, 6jcz:J, 6jcz:K, 6jcz:L, 6jd1:A, 6jd1:B, 6jd1:C, 6jd1:D, 6jd1:E, 6jd1:F, 6jd1:G, 6jd1:H, 6jd1:I, 6jd1:J, 6jd1:K, 6jd1:L, 6jd2:A, 6jd2:B, 6jd2:C, 6jd2:D, 6jd2:E, 6jd2:F, 6jd2:G, 6jd2:H, 6jd2:I, 6jd2:J, 6jd2:K, 6jd2:L, 6kou:A, 6kou:B, 6kou:C, 6kou:D, 6kou:E, 6kou:F, 6kou:G, 6kou:H, 6kou:I, 6kou:J, 6kou:K, 6kou:L, 6kpa:A, 6kpa:B, 6kpa:C, 6kpa:D, 6kpa:E, 6kpa:F, 6kpa:G, 6kpa:H, 6kpa:I, 6kpa:J, 6kpa:K, 6kpa:L, 6kph:A, 6kph:B, 6kph:C, 6kph:D, 6kph:E, 6kph:F, 6kph:G, 6kph:H, 6kph:I, 6kph:J, 6kph:K, 6kph:L, 6kpi:A, 6kpi:B, 6kpi:C, 6kpi:D, 6kpi:E, 6kpi:F, 6kpi:G, 6kpi:H, 6kpi:I, 6kpi:J, 6kpi:K, 6kpi:L, 6kpj:A, 6kpj:B, 6kpj:C, 6kpj:D, 6kpj:E, 6kpj:F, 6kpj:G, 6kpj:H, 6kpj:I, 6kpj:J, 6kpj:K, 6kpj:L, 6kq4:A, 6kq4:B, 6kq4:C, 6kq4:D, 6kq4:E, 6kq4:F, 6kq4:G, 6kq4:H, 6kq4:I, 6kq4:J, 6kq4:K, 6kq4:L, 6kqj:A, 6kqj:B, 6kqj:C, 6kqj:D, 6kqj:E, 6kqj:F, 6kqj:G, 6kqj:H, 6kqj:I, 6kqj:J, 6kqj:K, 6kqj:L, 6kqk:A, 6kqk:B, 6kqk:C, 6kqk:D, 6kqk:E, 6kqk:F, 6kqk:G, 6kqk:H, 6kqk:I, 6kqk:J, 6kqk:K, 6kqk:L, 6kqo:A, 6kqo:B, 6kqo:C, 6kqo:D, 6kqo:E, 6kqo:F, 6kqo:G, 6kqo:H, 6kqo:I, 6kqo:J, 6kqo:K, 6kqo:L
26 4tsk:A 333 51 0.0389 0.0541 0.3529 2.3
27 6jx2:B 327 51 0.0389 0.0550 0.3529 2.4 6jx2:A, 6jx2:C, 6jx2:D
28 8k32:C 333 37 0.0346 0.0480 0.4324 4.1 8k32:A, 8k32:B, 8k32:D
29 4ayg:A 1028 26 0.0194 0.0088 0.3462 4.1 4ayg:B, 3hz3:A, 3klk:A, 3kll:A
30 4ypo:A 325 33 0.0302 0.0431 0.4242 4.4 4ypo:B
31 6l2i:A 324 51 0.0389 0.0556 0.3529 4.7 6l2i:B, 6l2z:A, 6l2z:B
32 6nje:A 297 63 0.0410 0.0640 0.3016 5.1
33 6bul:B 327 49 0.0367 0.0520 0.3469 5.3 6aqj:A, 6aqj:B, 6bul:A, 6c55:A, 6c55:B, 6c5n:A, 6c5n:B, 7ke2:B, 7ke2:A, 7kh7:A, 7kh7:B, 6vo2:A, 6vo2:B, 5w3k:A, 5w3k:B
34 7nba:K 331 76 0.0389 0.0544 0.2368 5.5
35 4p07:A 570 75 0.0454 0.0368 0.2800 6.0 3elq:A, 3elq:B, 3ets:A, 3ets:B, 3ett:A, 3ett:B, 4p04:B, 4p05:A, 4p05:B, 4p06:A, 4p06:B, 4p07:B
36 6pej:A 257 77 0.0475 0.0856 0.2857 7.2 6pej:B, 6pej:C, 6pej:D
37 7epw:A 373 37 0.0346 0.0429 0.4324 9.2 4a6n:A, 4a6n:B, 4a6n:C, 4a6n:D, 4a99:A, 4a99:C, 4a99:B, 4a99:D, 7epv:A, 4guv:A, 4guv:B, 4guv:C, 4guv:D, 3p9u:A, 3p9u:B, 3p9u:C, 3p9u:D, 3v3n:A, 3v3n:B, 3v3n:C, 3v3n:D, 3v3o:A, 3v3o:B, 3v3o:C, 3v3o:D, 2xdo:A, 2xdo:B, 2xdo:C, 2xdo:D, 2xyo:A, 2xyo:B, 2xyo:C, 2xyo:D, 2y6q:A, 2y6q:B, 2y6q:C, 2y6q:D, 2y6r:A, 2y6r:B, 2y6r:C, 2y6r:D
38 3ge4:A 161 50 0.0410 0.1180 0.3800 9.2 3ge4:B, 3ge4:C, 3ge4:D, 3ge4:E, 3ge4:F, 3ge4:G, 3ge4:H, 3ge4:I, 3ge4:J, 3ge4:K, 3ge4:L
39 1jro:A 450 51 0.0410 0.0422 0.3725 9.7 1jro:C, 1jro:E, 1jro:G, 1jrp:A, 1jrp:C, 1jrp:E, 1jrp:G, 2w3r:A, 2w3r:C, 2w3r:E, 2w3r:G, 2w3s:A, 2w3s:C, 2w3s:E, 2w3s:G, 2w54:A, 2w54:C, 2w54:E, 2w54:G, 2w55:A, 2w55:C, 2w55:E, 2w55:G

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218