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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NYKEKLQQYAELLVKVGMNVQPKQPVFIRSSVETLELTHLIVEEAYHCGASDVRVVYSDPTLKRLKFENESVEHFANHEI
KSYDVEARMDYVKRGAANLALISEDPDLMDGIDSQKLQAFQQQNARAFKGYMESVQKNQFPWVVAAFPSKAWAKRVYPEL
SVEEAYIKFIDEVFDIVRIDGNDPVENWRQHIANLSVYAQKLQQKNYHALHYVSEGTDLTVGLAKNHIWEDATSYVNGKE
QAFIANIPTEEVFTAPDRNRVDGYVTNKLPLSYNGTIIDQFKLMFKDGEIIDFSAEKGEAVLKDLINTDEGSRRLGEVAL
VPDDSPISNRNTIFYNTLFDENAACHLAIGSAYAFNIQGGTEMTVEEKIASGLNDSNVHVDFMIGSSDLTIYGIFEDGSK
ELVFENGNWASTF

The query sequence (length=413) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1zjc:A 413 413 1.0000 1.0000 1.0000 0.0
2 4icq:A 413 413 0.4794 0.4794 0.4794 2.45e-131 4icq:B, 4icr:A, 4icr:B, 4ics:A, 4ics:B
3 2ayi:A 397 408 0.3753 0.3904 0.3799 9.29e-98 2ayi:B, 2ayi:C, 2ayi:D, 2ayi:E
4 2io4:B 246 225 0.1211 0.2033 0.2222 0.13 2io4:D
5 7bl2:9P1 338 33 0.0412 0.0503 0.5152 0.24 7bl3:9P, 7bl4:9, 7bl5:9, 7bl6:9, 4csu:9, 5m04:A
6 3wgy:B 324 79 0.0605 0.0772 0.3165 1.1 3wgq:A, 3wgz:B
7 4lc9:A 567 33 0.0291 0.0212 0.3636 1.3
8 2faq:A 295 108 0.0508 0.0712 0.1944 3.3 2faq:B, 2far:A, 2far:B
9 5jxf:A 694 80 0.0508 0.0303 0.2625 3.3 5jxf:B
10 4pfy:A 539 20 0.0315 0.0241 0.6500 4.2 4pft:A, 4pft:B, 4pfy:B
11 8hsg:I 1096 53 0.0363 0.0137 0.2830 4.7 3aoi:C, 3aoi:H, 3aoi:M, 4gzy:C, 4gzz:C
12 2a68:C 1119 53 0.0363 0.0134 0.2830 4.7 2a68:M, 2a69:C, 2a69:M, 2a6h:C, 2a6h:M, 3aoh:C, 2be5:C, 2be5:M, 6cuu:C, 5d4c:C, 5d4c:M, 5d4d:C, 5d4d:M, 5d4e:C, 5d4e:M, 3dxj:C, 3dxj:M, 5e17:C, 5e18:C, 7eh0:C, 7eh1:C, 7eh2:C, 7eh2:M, 3eql:C, 3eql:M, 4g7h:C, 4g7h:M, 4g7o:C, 4g7o:M, 4g7z:C, 4g7z:M, 8hsr:I, 5i2d:C, 5i2d:N, 1i6v:C, 1iw7:C, 1iw7:M, 6kqd:C, 6kqd:M, 6kqe:C, 6kqf:C, 6kqg:C, 6kqh:C, 6kql:C, 6kqm:C, 6kqn:C, 6l74:C, 6lts:C, 6m6a:C, 6m6c:C, 7mlb:C, 7mli:C, 7mlj:C, 4mq9:C, 2o5i:C, 2o5i:M, 2o5j:C, 2o5j:M, 4oin:C, 4oio:C, 4oip:C, 4oiq:C, 4oir:C, 6ovr:C, 6ovy:C, 6ow3:C, 6oy5:C, 6oy6:C, 6oy7:C, 6p70:C, 6p71:C, 2ppb:C, 2ppb:M, 4q4z:C, 4q5s:C, 7rdq:C, 1smy:C, 1smy:M, 5tmc:C, 5tmf:C, 5vo8:C, 5voi:C, 8w8n:C, 8w8o:C, 8w8p:C, 6wox:C, 6woy:C, 4wqs:C, 4wqs:M, 5x21:C, 5x22:C, 5x22:M, 4xln:C, 4xln:I, 4xlr:C, 4xlr:I, 1ynj:C, 1ynn:C, 1zyr:C, 1zyr:M
13 4bb9:A 596 33 0.0266 0.0185 0.3333 9.5 4bba:A, 4ly9:A, 4ly9:B, 4mqu:A, 4mqu:B, 4mro:A, 4mro:B, 4msu:A, 4msu:B, 4ohk:A, 4ohk:B, 4ohm:A, 4ohm:B, 4oho:A, 4oho:B, 4ohp:A, 4ohp:B, 4olh:A, 4olh:B, 4op1:A, 4op1:B, 4op2:A, 4op2:B, 4op3:A, 4op3:B, 4px2:A, 4px2:B, 4px3:A, 4px3:B, 4px5:A, 4px5:B, 4pxs:A, 4pxs:B
14 1nf2:A 267 75 0.0508 0.0787 0.2800 9.8 1nf2:B, 1nf2:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218