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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NVYQLKEELIEYAKSIGVDKIGFTTADTFDSLKDRLILQESLGYLSGFEEPDIEKRVTPKLLLPKAKSIVAIALAYPSRM
KDAPRSTRTERRGIFCRASWGKDYHDVLREKLDLLEDFLKSKHDIRTKSMVDTGELSDRAVAERAGIGFSAKNCMITTPE
YGSYVYLAEMITNIPFEPDVPIEDMCGSCTKCLDACPTGALVNPGQLNAQRCISFLTQTKGFLPDEFRTKIGNRLYGCDT
CQTVCPLNKGKDFHLHPEMEPDPEIAKPLLKPLLAISNREFKEKFGHVSGSWRGKKPIQRNAILALAHFKDASALPELTE
LMHKDPRPVIRGTAAWAIGKIGDPAYAEELEKALEKEKDEEAKLEIEKGIELLKASGMT

The query sequence (length=379) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5d08:A 384 380 1.0000 0.9870 0.9974 0.0 5d08:B, 5d0a:A, 5d0a:B, 5d0a:C, 5d0a:D, 5d0b:A, 5d0b:B, 5t8y:B, 5t8y:A
2 5d6s:A 370 339 0.4354 0.4459 0.4867 5.25e-111 5d6s:B, 5d6s:C, 5d6s:D, 5d6s:E
3 4ur3:A 458 142 0.1029 0.0852 0.2746 2.25e-09 5m2g:A, 5m2g:B, 5m8u:A, 5m8u:B, 5m8w:A, 5m8w:B, 5m8x:A, 5m8x:B, 5m8y:A, 5m8y:B, 5m8z:A, 5m8z:B, 5m90:A, 5m90:B, 5m91:A, 5m91:B, 5m92:A, 5m92:B, 5ma0:A, 5ma0:B, 5ma1:A, 5ma1:B, 5ma2:A, 5ma2:B, 5maa:A, 5maa:B, 5obi:A, 5obi:B, 5obp:A, 5obp:B, 4uqu:A, 4uqu:B, 4ur0:A, 4ur0:B, 4ur1:A, 4ur1:B, 4ur2:A, 4ur2:B, 4ur3:B, 4ur3:C, 4ur3:D, 4ur3:E, 4ur3:F
4 8q4h:A 503 249 0.1715 0.1292 0.2610 3.26e-08 8q4h:B
5 7p0h:A 411 60 0.0660 0.0608 0.4167 0.002 7p0h:B, 7p0h:C, 7p0h:D
6 7p0h:A 411 80 0.0712 0.0657 0.3375 0.22 7p0h:B, 7p0h:C, 7p0h:D
7 7p0h:A 411 75 0.0686 0.0633 0.3467 0.47 7p0h:B, 7p0h:C, 7p0h:D
8 7p0h:A 411 65 0.0580 0.0535 0.3385 1.9 7p0h:B, 7p0h:C, 7p0h:D
9 7p0h:A 411 66 0.0633 0.0584 0.3636 2.2 7p0h:B, 7p0h:C, 7p0h:D
10 7p0h:A 411 39 0.0501 0.0462 0.4872 9.0 7p0h:B, 7p0h:C, 7p0h:D
11 8jjr:c 86 70 0.0554 0.2442 0.3000 0.002 8jw0:c, 8jze:c, 8jzf:c
12 3lww:C 871 28 0.0449 0.0195 0.6071 0.008 1f59:A, 1f59:B, 1m5n:S, 1o6o:A, 1o6o:C, 1o6o:B, 1o6p:B, 1o6p:A, 1qgr:A
13 2q5d:B 845 28 0.0449 0.0201 0.6071 0.008
14 8wm6:C 80 69 0.0528 0.2500 0.2899 0.040 8wmj:C, 8wmv:C, 8wmw:C, 7y5e:CN, 7y5e:C2, 7y7a:C7, 7y7a:Co, 7y7b:C, 7y8a:C
15 6zxu:A 701 121 0.0712 0.0385 0.2231 0.045 4ras:A, 4ras:B, 4ras:C, 6zxu:B, 6zxu:C, 6zxx:A, 6zxx:B, 6zxx:C, 6zy0:A, 6zy0:B, 6zy0:C, 6zy1:A, 6zy1:B, 6zy1:C
16 7vw6:A 913 55 0.0501 0.0208 0.3455 0.14 7e5z:A, 8j83:A, 7xqw:A
17 7ew6:C 81 70 0.0528 0.2469 0.2857 0.19 7a4p:C, 8bcv:C, 8bcw:C, 7dkz:C, 7ewk:C, 7f9o:C, 7f9o:g, 8htu:C, 6igz:C, 8j6z:C, 8j7a:C, 8j7b:C, 7ksq:C, 7kux:C, 6l35:C, 5l8r:C, 3lw5:C, 6ly5:c, 2o01:C, 4rku:C, 7wfd:AC, 7wfe:BC, 7wg5:AC, 7wg5:BC, 8wgh:C, 2wsc:C, 2wse:C, 2wsf:C, 4xk8:C, 4xk8:c, 7xqp:C, 4y28:C, 6yac:C, 7yca:C, 6yez:C, 5zji:C, 6zoo:C, 6zxs:C
18 7dr0:C 80 70 0.0528 0.2500 0.2857 0.28 7dr1:C, 7dr2:aC, 7dr2:bC, 7dr2:cC, 7dr2:dC, 6zzx:C, 6zzy:C
19 4d4z:B 290 49 0.0501 0.0655 0.3878 0.30 4d4z:A, 4d50:A, 4d50:B
20 7q2x:D 994 62 0.0580 0.0221 0.3548 0.43 7q2y:D
21 7qen:D 1050 62 0.0580 0.0210 0.3548 0.46
22 5oy0:c 81 69 0.0501 0.2346 0.2754 0.50 8am5:c, 8asl:c, 8asp:c, 7blz:C, 7coy:aC, 7coy:bC, 7coy:cC, 7dwq:C, 7f4v:aC, 7f4v:bC, 7f4v:cC, 4fe1:C, 7fix:C1, 7fix:C2, 7fix:C3, 6fos:C, 6hqb:C, 1jb0:C, 6jeo:aC, 6jeo:bC, 6jeo:cC, 6jeo:dC, 1k0t:A, 6k33:aC, 6k33:bC, 6k33:cC, 6k61:C, 6k61:c, 6kif:C, 6kif:N, 6kif:g, 6kig:C, 6kig:N, 6kig:g, 6kmw:aC, 6kmw:bC, 6kmw:cC, 6kmx:aC, 6kmx:bC, 6kmx:cC, 4kt0:C, 6l4u:C, 4l6v:C, 4l6v:c, 4l6v:3, 6lu1:C, 7lx0:N, 7lx0:c, 7lx0:C, 7m75:C, 7m76:C, 7m78:C, 6nwa:C, 6nwa:c, 6nwa:N, 7o1v:C, 5oy0:C, 5oy0:3, 3pcq:C, 6pfy:C, 6pfy:N, 6pfy:a, 6pgk:C, 6pgk:N, 6pgk:a, 6pnj:C, 6pnj:N, 6pnj:c, 7qco:C, 7qco:H, 7qco:h, 7qco:c, 6qph:C, 6rhz:C, 7s3d:C, 7s3d:N, 7s3d:c, 6sl5:C, 6tcl:C1, 6tcl:C2, 6tcl:C, 6tcl:CC, 6tra:C, 6trc:C, 6trc:c, 6trc:3, 6trd:C, 6trd:c, 6trd:3, 7umh:C, 7umh:N, 7umh:c, 6uzv:C, 6uzv:c, 6uzv:3, 6vpv:C, 6vpv:c, 6vpv:3, 8wey:C, 7y3f:C, 6yxr:C, 5zf0:C1, 5zf0:C2, 5zf0:C3, 5zf0:C4, 5zf0:C6, 5zf0:C5, 5zgb:C, 5zgh:C
23 7bgi:C 80 69 0.0501 0.2375 0.2754 0.59 7blx:C, 8cmo:C, 7d0j:C, 7dz7:C, 7dz8:C, 8h2u:C, 6ijj:C, 6ijo:C, 6jo5:C, 6jo6:C, 7r3k:C, 7wyi:C, 7wzn:C, 7zq9:C, 7zqc:C, 7zqd:C, 7zqd:C2
24 6fah:E 393 80 0.0633 0.0611 0.3000 0.74 6fah:A
25 8ahx:B 113 18 0.0290 0.0973 0.6111 0.81 8rb8:B, 8rb9:B, 8rbq:B
26 8ahx:B 113 83 0.0607 0.2035 0.2771 1.5 8rb8:B, 8rb9:B, 8rbq:B
27 5owu:A 860 86 0.0633 0.0279 0.2791 0.86
28 7zc6:C 435 64 0.0501 0.0437 0.2969 1.3
29 5t5i:P 81 18 0.0211 0.0988 0.4444 1.3 5t5i:G, 5t5m:G, 5t61:E, 5t61:K, 5t61:Q, 5t61:W, 5t61:c, 5t61:i, 5t61:o, 5t61:u
30 5t5i:P 81 21 0.0237 0.1111 0.4286 6.0 5t5i:G, 5t5m:G, 5t61:E, 5t61:K, 5t61:Q, 5t61:W, 5t61:c, 5t61:i, 5t61:o, 5t61:u
31 7bkd:A 664 74 0.0554 0.0316 0.2838 1.5 7bkb:A, 7bkb:a, 7bkc:A, 7bkc:a, 7bkd:a, 7bke:A, 7bke:a
32 8oh5:C 1172 18 0.0290 0.0094 0.6111 1.6 8oh5:F, 8oh5:I, 8oh5:L, 8oh9:C, 8oh9:F, 8oh9:I, 8oh9:L
33 5x49:A 441 46 0.0501 0.0431 0.4130 2.8 5x49:B
34 3i01:A 673 67 0.0633 0.0357 0.3582 3.4 3i01:B, 3i01:C, 3i01:D, 3i04:A, 3i04:B, 3i04:C, 3i04:D, 1mjg:A, 1mjg:B, 1mjg:C, 1mjg:D, 1oao:A, 1oao:B, 6x5k:A, 6x5k:B, 6x5k:C, 6x5k:D, 2z8y:A, 2z8y:B, 2z8y:C, 2z8y:D
35 6qj3:A 980 69 0.0501 0.0194 0.2754 3.6 6qj4:A
36 7bkb:L 79 23 0.0237 0.1139 0.3913 4.1 7bkb:l, 7bkc:L, 7bkc:l
37 1clf:A 55 69 0.0449 0.3091 0.2464 4.3
38 1clf:A 55 19 0.0237 0.1636 0.4737 9.5
39 6u8y:N 176 16 0.0264 0.0568 0.6250 4.4 6u8y:n
40 6tg9:A 949 28 0.0369 0.0148 0.5000 4.9 6tg9:E, 6tga:A, 6tga:E
41 8sl1:A 843 47 0.0422 0.0190 0.3404 5.4
42 8ic6:B 855 52 0.0422 0.0187 0.3077 5.6 8ic6:A, 8ic7:B, 8ic7:A
43 8a6t:A 571 48 0.0449 0.0298 0.3542 6.0 8a6t:D, 8bew:A, 8bew:D
44 7p8n:B 613 82 0.0528 0.0326 0.2439 6.8 7p5h:B, 7p5h:E, 7p5h:b, 7p5h:e, 7p8n:b, 7p91:b, 7p91:B, 7p92:B
45 2r7d:A 461 78 0.0607 0.0499 0.2949 7.1 2r7d:B, 2r7d:C
46 1fca:A 55 70 0.0449 0.3091 0.2429 9.2 1fdn:A, 2fdn:A
47 7y3m:C 70 49 0.0343 0.1857 0.2653 9.5 8u15:C, 8u15:F, 8u16:C, 8u16:F, 8u17:C, 8u17:F, 7y3m:B, 7y3m:A, 7y3m:F, 7y3m:J, 7y3m:I
48 7z6q:B 123 16 0.0237 0.0732 0.5625 9.6 8gwa:B, 6m32:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218