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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NRSIRDGDNPELLEERRMATFDTDKMAAVIYGSEEFARRRREITDAVSKIPELADIKPYPFLTREEKVTEGTRKISILTK
YLNQLIDRDNEEESLHLHREVIGYEGHPFALHDALFIPTLQSQASDEQQEKWLERARRREIIGCYAQTELGHGSNLRNLE
TTAVYDIASQEFVLHTPTTTALKWWPGALGKSCNYALVVAELIIKRNNYGPHFFMVQLRDEKTHIPLKGVTVGDIGPKMN
FNAADNGYLGLNNLRVPRTNLLMRHCKVEADGTYVKPPHAKIGYSGMVKIRSQMAMEQGLFLAHALTIAARYSAVRRQGH
LDDKQVEVKVLDYQTQQHRLFPSLARAYAFIFTGFETIHLYSQLLKDVDMGNTSGMADLHALTSGLKSVVAHETGEGIEQ
ARMACGGHGYSMASYISVVYGIAIGGCTYAGENMVMLLQLARYLVKSVELIKAGKAKKLGPVASYLADKSDETDLTSLNG
YVKMFENMARRQAWKATEKFLKLMESGESREVAWNKSAVELTRASRLHTRLFIIEAFMRRVSRIEDIPVKEVLTDLLHLH
VNYELLDVATYALEFMSFTQLDYVRDQLYLYLEKIRPNAVSLVDSFQISDMQLRSVLGRRDGHVYENLFKWAKSSPLNNA
DVLPSVEKYLKPMMEKAKLAAA

The query sequence (length=662) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5k3j:A 662 662 1.0000 1.0000 1.0000 0.0 5k3j:B
2 5k3i:A 661 665 0.6843 0.6853 0.6812 0.0 5k3i:B, 5k3i:C, 5k3i:D, 5k3i:E, 5k3i:F, 5k3i:G, 5k3i:H
3 1is2:A 637 647 0.4230 0.4396 0.4328 5.12e-175 2ddh:A, 1is2:B
4 7q86:A 612 642 0.4079 0.4412 0.4206 1.19e-159 7q86:B
5 2fon:B 656 668 0.3792 0.3826 0.3757 3.89e-138 2fon:A, 2fon:C
6 1w07:B 658 665 0.3807 0.3830 0.3789 6.85e-136 1w07:A
7 5ys9:A 692 667 0.3051 0.2919 0.3028 2.99e-96 5ys9:B
8 5y9d:A 687 678 0.3006 0.2897 0.2935 2.43e-86 5y9d:B
9 2pg0:A 380 338 0.1224 0.2132 0.2396 6.56e-08 2pg0:B
10 7y0a:C 387 157 0.0544 0.0930 0.2293 3.76e-05 1jqi:A, 1jqi:B, 8sgs:A, 8sgs:B, 8sgs:C, 8sgs:D, 2vig:A, 2vig:B, 2vig:C, 2vig:D, 2vig:E, 2vig:F, 2vig:G, 2vig:H, 7y0a:A, 7y0a:B, 7y0a:D, 7y0b:A, 7y0b:B, 7y0b:C, 7y0b:D
11 2wbi:B 398 147 0.0604 0.1005 0.2721 4.16e-05 2wbi:A
12 3sf6:A 387 148 0.0574 0.0982 0.2568 9.16e-05
13 2r0m:A 390 161 0.0529 0.0897 0.2174 1.27e-04 2r0n:A, 1siq:A, 1sir:A
14 3swo:A 388 134 0.0559 0.0954 0.2761 0.001 3swo:D, 3swo:B, 3swo:C
15 4m9a:B 376 153 0.0574 0.1011 0.2484 0.001 4m9a:A
16 5ol2:F 378 216 0.0725 0.1270 0.2222 0.002 5ol2:C
17 8w0t:A 398 159 0.0574 0.0955 0.2390 0.003 8w0t:B, 8w0t:C, 8w0t:D, 8w0u:A, 8w0u:B, 8w0u:C, 8w0u:D, 8w0z:A, 8w0z:B, 8w0z:C, 8w0z:D, 8w0z:E, 8w0z:F, 8w0z:G, 8w0z:H
18 6fah:D 379 145 0.0589 0.1029 0.2690 0.004 6fah:C
19 4n5f:A 378 154 0.0559 0.0979 0.2403 0.006 4n5f:B
20 4hr3:A 407 143 0.0544 0.0885 0.2517 0.018
21 5lnx:D 374 248 0.0831 0.1471 0.2218 0.024 5lnx:A, 5lnx:B, 5lnx:C, 5lnx:E, 5lnx:F, 5lnx:G, 5lnx:H
22 3oib:A 381 164 0.0619 0.1076 0.2500 0.042 3oib:B, 3p4t:A, 3p4t:B
23 6wy8:B 384 70 0.0363 0.0625 0.3429 0.067 6wy8:D, 6wy9:A
24 6t3e:B 325 66 0.0347 0.0708 0.3485 0.068 6t3e:A
25 3gqt:C 385 68 0.0317 0.0545 0.3088 0.076 3d6b:C, 3eon:C, 3gnc:A, 3gnc:B, 3gnc:C, 3gnc:D, 3gqt:A, 3gqt:B
26 2ix6:A 416 54 0.0272 0.0433 0.3333 0.082 2ix5:A, 2ix5:B, 2ix5:C, 2ix5:D, 2ix6:C, 2ix6:F, 2ix6:B, 2ix6:E, 2ix6:D
27 4iv6:B 383 139 0.0498 0.0862 0.2374 0.11 4iv6:A
28 3pfd:C 369 140 0.0559 0.1003 0.2643 0.14 3pfd:A, 3pfd:B, 3pfd:D
29 1nee:A 135 99 0.0468 0.2296 0.3131 0.17
30 3r7k:A 378 182 0.0695 0.1217 0.2527 0.20 3r7k:B, 3r7k:C, 3r7k:D
31 2dvl:A 370 139 0.0559 0.1000 0.2662 0.22 2dvl:B
32 3owa:C 587 141 0.0589 0.0664 0.2766 0.33 3owa:A, 3owa:B, 3owa:D
33 2z1q:B 549 156 0.0559 0.0674 0.2372 0.33 2z1q:A
34 4x28:A 386 49 0.0272 0.0466 0.3673 0.39 4x28:B
35 7szv:A 372 145 0.0498 0.0887 0.2276 0.88 7szv:B
36 3mdd:A 385 138 0.0483 0.0831 0.2319 0.97 3mdd:B, 3mde:A, 3mde:B, 1udy:A, 1udy:B, 1udy:C, 1udy:D
37 2eba:A 380 185 0.0574 0.1000 0.2054 1.1 2eba:D, 2eba:C, 2eba:E, 2eba:F, 2eba:G, 2eba:H, 2eba:I
38 2a1t:C 388 142 0.0483 0.0825 0.2254 1.3 2a1t:A, 2a1t:B, 2a1t:D, 1egc:A, 1egc:B, 1egc:C, 1egc:D, 1egd:A, 1egd:B, 1egd:C, 1egd:D, 1ege:A, 1ege:B, 1ege:C, 1ege:D, 4p13:A, 4p13:B, 4p13:C, 4p13:D, 8sgp:A, 8sgp:B, 8sgp:C, 8sgp:D, 1t9g:A, 1t9g:B, 1t9g:C, 1t9g:D
39 7rgn:A 340 108 0.0438 0.0853 0.2685 1.6
40 5w21:A 922 76 0.0302 0.0217 0.2632 2.3 7ysh:A, 7ysu:A, 7ysw:A
41 8phe:A 551 226 0.0710 0.0853 0.2080 2.8 8phe:B, 8phf:A, 8phf:B
42 6cu5:A 314 51 0.0257 0.0541 0.3333 3.1 6cu5:B, 8ft7:A, 8ft7:B
43 8sgr:A 393 61 0.0272 0.0458 0.2951 3.3 1ivh:A, 1ivh:B, 1ivh:C, 1ivh:D, 8sgr:B, 8sgr:C, 8sgr:D
44 4l1f:A 380 196 0.0665 0.1158 0.2245 3.4 4l1f:B
45 7s7g:A 571 143 0.0468 0.0543 0.2168 4.8 3b96:A, 2uxw:A
46 2d29:A 386 54 0.0257 0.0440 0.3148 5.9 2d29:B
47 4s1k:A 236 54 0.0257 0.0720 0.3148 6.3 4s1l:A, 4zqx:A
48 1ukw:A 379 378 0.1284 0.2243 0.2249 6.8 1ukw:B
49 4irn:A 378 43 0.0257 0.0450 0.3953 8.7 4irn:B, 4irn:C, 4irn:D, 4irn:E, 4irn:F, 4irn:G, 4irn:H
50 4fgm:A 587 57 0.0257 0.0290 0.2982 9.1

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218