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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NRELTYITNSIAEAQRVMAAMLADERLLATVRKVADACIASIAQGGKVLLAGNGGSAADAQHIAGEFVSRFAFDRPGLPA
VALTTDTSILTAIGNDYGYEKLFSRQVQALGNEGDVLIGYSTSGKSPNILAAFREAKAKGMTCVGFTGNRGGEMRELCDL
LLEVPSADTPKIQEGHLVLGHIVCGLVEHSIFGKQ

The query sequence (length=195) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2x3y:A 202 193 0.9897 0.9554 1.0000 2.79e-142 5ltz:A, 5ltz:B, 5ltz:D, 5ltz:C, 5lu5:A, 5lu5:B, 5lu5:C, 5lu5:D, 5lu6:A, 5lu6:B, 5lu6:C, 5lu6:D, 5lu7:A, 5lu7:B, 5lu7:D, 5lu7:C, 8v2t:A, 8v4j:A, 2x3y:B, 2x3y:C, 2x3y:D, 2x3y:E, 2x3y:F, 2x3y:G, 2x3y:H, 2xbl:A, 2xbl:B, 2xbl:D, 2xbl:C
2 1x92:B 197 172 0.3949 0.3909 0.4477 1.05e-47 1x92:A
3 5i01:A 184 178 0.4051 0.4293 0.4438 1.08e-43 5i01:B, 5i01:C, 5i01:D
4 2i22:B 178 183 0.3641 0.3989 0.3880 5.89e-36 2i22:C
5 4lzj:B 299 143 0.1692 0.1104 0.2308 6.17e-05 4lzj:C, 4lzj:D, 4lzj:A
6 8fdb:B 333 49 0.0872 0.0511 0.3469 0.001 8eym:A, 8eym:B, 8fdb:A
7 5uqi:A 188 160 0.2051 0.2128 0.2500 0.001
8 8tx9:A 190 73 0.1077 0.1105 0.2877 0.052 8tx9:B, 8tx9:C, 8tx9:D
9 8zmr:A 384 97 0.1333 0.0677 0.2680 0.093
10 4heq:A 145 72 0.1231 0.1655 0.3333 0.51 4heq:B
11 6s9u:A 520 92 0.1128 0.0423 0.2391 0.63
12 3jrv:B 144 49 0.0821 0.1111 0.3265 2.6 3jrv:A
13 8cnr:A 548 81 0.1385 0.0493 0.3333 5.0 8cns:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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