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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NLSQLAAHSTIPEPLLLFKDNRTDTHPLRGLSQYGPYSACFNLPGQVRLAYLAPTEHMRKLDAIVRELQNPATPKEATNY
YVEYGGFEKVFKVPLVMPQEHLRCLALDECHGVAANGNGLALADKIVQSMSGLFRQKHAFDVLLVYLPASWKKCFEYDGF
DLHDRIKAKVAPLNLPIQIINDTALTRQCRANVMWGVSVALYAKAGGIPWKLADWDKDEAYIGLSYAIKKNAEGQEYTTC
CSQVFDPDGTGFEFVAYDTREFITDRKGNPYLSYQEMQSVLSKSLHLYQSSHNGRMPRKIFIHKTTHFTEDEIQGAFDSF
SSSTEIELVQIIQSTNWYGLKVDGKKGDKPVAPASYPVDRGLYQPLTESECLLWTQGSVMGVNQQNPGQPVFKEAALTPL
PNPIMLRRFSGNGGWHATCSSILALTKVDWNNNTLYKKLPVTLVYSQVFADVVKQTPEIVNEIYDYRFFM

The query sequence (length=470) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8in8:C 470 470 1.0000 1.0000 1.0000 0.0 8jl0:B, 8k87:A, 8k87:F, 8k88:A
2 8isz:A 465 491 0.2447 0.2473 0.2342 3.10e-31 8it0:A, 8it0:E, 8it1:I, 8it1:M, 8it1:A, 8it1:E, 8j8h:A, 8j9g:A, 8j9p:A, 8j9p:C, 8jay:A, 8jay:C, 8jay:I, 8jay:M, 8k9g:A, 8k9g:E, 8u72:C, 8u72:E, 8u72:I, 8u72:G
3 8k34:B 434 474 0.2340 0.2535 0.2321 1.12e-30 8ifl:B, 8ifl:G, 8ifl:K, 8ifl:O, 8ifm:B, 8ifm:G, 8ifm:K, 8ifm:O
4 8qlp:B 452 471 0.2404 0.2500 0.2399 1.35e-28 8qlp:F, 8qlp:J, 8qlp:N
5 8u7b:C 507 333 0.1766 0.1637 0.2492 3.85e-28
6 8oz6:B 473 501 0.2511 0.2495 0.2355 1.48e-26 8ffi:B, 8ffi:F, 8ffi:L, 8ffi:N, 8i87:F, 8i87:T, 8i87:B, 8i87:D, 8i88:B, 8j7s:A, 8j7s:E, 8j7s:I, 8j7s:M, 8jr8:A, 8jr8:C, 8oz6:D, 8oz6:F, 8oz6:H, 8ozd:B, 8ozd:D, 8oze:F, 8oze:H, 8ozf:B, 8ozf:E, 8ozf:G, 8ozf:M, 8ozg:B, 8ozg:E, 8ozg:G, 8ozg:M, 8ozi:B, 8ozi:D, 8ozi:F, 8ozi:H, 8sp0:B, 8sp0:F, 8sp3:B, 8sp3:F, 8spo:B, 8spo:F, 8spo:L, 8spo:N, 8squ:B
7 8ifk:B 409 475 0.2340 0.2689 0.2316 1.46e-25
8 2f8s:A 704 310 0.1489 0.0994 0.2258 1.22e-08 2f8t:A
9 1yvu:A 682 291 0.1383 0.0953 0.2234 5.39e-07
10 6qzk:A 746 310 0.1319 0.0831 0.2000 0.014
11 4f1n:A 904 111 0.0638 0.0332 0.2703 0.089 5the:A, 5the:C, 5the:E, 5the:G
12 4f1n:B 853 111 0.0638 0.0352 0.2703 0.092
13 5awh:B 715 458 0.2085 0.1371 0.2140 0.66
14 7vem:A 347 31 0.0319 0.0432 0.4839 0.74 7vem:B
15 8p2f:E 670 23 0.0277 0.0194 0.5652 0.80 8p2g:E, 8p2h:E
16 5awh:A 759 466 0.2106 0.1304 0.2124 1.1 6d8a:A, 6d8a:F, 6d8f:A, 6d8f:F, 6d8p:A, 6d8p:B, 6d92:A, 6d92:F, 6d95:A, 6d95:F, 6d9k:A, 6d9k:F, 6d9l:A, 6d9l:F
17 1y7o:B 178 113 0.0574 0.1517 0.2389 1.5 1y7o:A, 1y7o:C, 1y7o:E, 1y7o:F, 1y7o:G
18 5xou:B 574 151 0.0702 0.0575 0.2185 2.0 5xou:A
19 5xow:A 684 151 0.0702 0.0482 0.2185 2.6 3dlb:A, 3dlb:B, 3dlh:A, 3dlh:B, 3f73:A, 3f73:B, 5gq9:B, 3hjf:A, 3hk2:A, 3hk2:B, 3ho1:A, 4kpy:A, 4kpy:B, 4n41:A, 4n41:B, 4n47:A, 4n76:B, 4nca:A, 4nca:B, 4ncb:A, 4ncb:B, 5xp8:A, 5xpa:A, 5xpg:A, 5xq2:A, 5xq2:B
20 4n76:A 641 151 0.0702 0.0515 0.2185 2.7 5gq9:A, 3hxm:A
21 3o5b:A 479 74 0.0468 0.0459 0.2973 4.8 3o5b:B, 3o80:A, 3o8m:A
22 8jjr:f 169 81 0.0489 0.1361 0.2840 8.0
23 3c5m:B 378 72 0.0489 0.0608 0.3194 9.7 3c5m:A, 3c5m:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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