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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NASIYQEFVNKYSLSKTLRFELIPQGKTLENIKARGLILDDEKRAKDYKKAKQIIDKYHQFFIEEILSSVCISEDLLQNY
SDVYFKLKKSDDDNLQKDFKSAKDTIKKQISEYIKDSEKFKNLFNQNLIDAKKGQESDLILWLKQSKDNGIELFKANSDI
TDIDEALEIIKSFKGWTTYFKGFHENRKNVYSSNDIPTSIIYRIVDDNLPKFLENKAKYESLKDKAPEAINYEQIKKDLA
EELTFDIDYKTSEVNQRVFSLDEVFEIANFNNYLNQSGITKFNTIIGGKFVNGENTKRKGINEYINLYSQQINDKTLKKY
KMSVLFKQILSDTDKLEDDSDVVTTMQSFYEQIAAFKTVEEKSIKETLSLLFDDLKAQKLDLSKIYFKNDKSLTDLSQQV
FDDYSVIGTAVLEYITQQIAPKNQELIAKKTEKAKYLSLETIKLALEEFNKHRDIDKQCRFEEILANFAAIPMIFDEIAQ
NKDNLAQISIKYQNQGKKDLLQASAEDDVKAIKDLLDQTNNLLHKLKIFHISQSEDKANILDKDEHFYLVFEECYFELAN
IVPLYNKIRNYITQKPYSDEKFKLNFENSTLANGWDKNKEPDNTAILFIKDDKYYLGVMNKKNNKIFDDKAIKENKGEGY
KKIVYKLLPGANKMLPKVFFSAKSIKFYNPSEDILRIRNHSTHTKNGSPQKGYEKFEFNIEDCRKFIDFYKQSISKHPEW
KDFGFRFSDTQRYNSIDEFYREVENQGYKLTFENISESYIDSVVNQGKLYLFQIYNKDFSAYSKGRPNLHTLYWKALFDE
RNLQDVVYKLNGEAELFYRKQSIPKKITHPAKEAIANKNKDNPKKESVFEYDLIKDKRFTEDKFFFHCPITINFKSSGAN
KFNDEINLLLKEKANDVHILSIDRGERHLAYYTLVDGKGNIIKQDTFNIIGNDRMKTNYHDKLAAIERKDWKKINNIKEM
KEGYLSQVVHEIAKLVIEYNAIVVFEDLNFGFKRGRFKVEKQVYQKLEKMLIEKLNYLVFKDNEFDKTGGVLRAYQLTAP
FETFKKMGKQTGIIYYVPAGFTSKICPVTGFVNQLYPKYESVSKSQEFFSKFDKICYNLDKGYFEFSFDYKNFAAKGKWT
IASFGSRLINNWDTREVYPTKELEKLLKDYSIEYGHGECIKAAICGESDKKFFAKLTSVLNTILQMRNSKTGTELDYLIS
PVADVNGNFFDSRQAPKNMPQDADANGAYHIGLKGLMLLGRIKNNQEGKKLNLVIKNEEYFEFVQNRN

The query sequence (length=1268) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6gtg:A 1298 1297 0.9968 0.9738 0.9746 0.0 6gtc:A, 6gte:A, 6gtf:A, 6i1k:A, 6i1l:A
2 6gtd:A 1269 1279 0.9890 0.9882 0.9805 0.0 6i1l:D, 5nfv:A, 5ng6:A, 5ng6:C, 5ng6:E, 5ng6:G
3 5mga:A 1182 1280 0.9156 0.9822 0.9070 0.0
4 6iv6:A 1209 1312 0.4109 0.4309 0.3971 0.0
5 5xut:A 1217 1307 0.4125 0.4297 0.4002 0.0 5id6:A, 6nm9:B, 6nm9:D, 6nma:B, 6nmc:A, 6nmd:A, 6nme:A, 6omv:B, 5xus:A, 5xuu:A, 5xuz:A, 5xuz:E
6 8i54:A 1113 1293 0.4030 0.4591 0.3952 0.0
7 8h9d:A 1114 1285 0.3967 0.4515 0.3914 0.0
8 6kl9:A 1180 1295 0.4006 0.4305 0.3923 0.0
9 8kgf:A 1261 1360 0.3935 0.3957 0.3669 0.0
10 8sfn:A 1302 1370 0.3644 0.3548 0.3372 0.0 8sfh:A, 8sfl:A, 5xh6:A, 5xh7:A
11 8sfo:A 1240 1336 0.3596 0.3677 0.3413 0.0 8sfi:A, 8sfp:A, 8sfq:A, 8sfr:A
12 5kk5:A 1201 1318 0.3604 0.3805 0.3467 0.0
13 5b43:A 1272 1356 0.3628 0.3616 0.3392 0.0
14 6p7m:A 1070 567 0.2098 0.2486 0.4691 4.14e-149 6p7n:A, 6p7n:E
15 6p7m:A 1070 641 0.1506 0.1785 0.2980 2.90e-52 6p7n:A, 6p7n:E
16 6klb:A 1118 551 0.2074 0.2352 0.4773 4.84e-149 6klb:D
17 6klb:A 1118 653 0.1609 0.1825 0.3124 2.27e-62 6klb:D
18 8sfj:A 1001 752 0.2240 0.2837 0.3777 9.69e-135
19 8sfj:A 1001 334 0.0883 0.1119 0.3353 5.60e-36
20 8d4a:A 1207 265 0.0465 0.0489 0.2226 8.19e-05 8d4b:A
21 8d4a:A 1207 91 0.0197 0.0207 0.2747 1.9 8d4b:A
22 7v94:A 1076 169 0.0308 0.0362 0.2308 0.025 7v93:A
23 8xq7:A 1041 119 0.0221 0.0269 0.2353 0.092 8xq7:B
24 8pdv:A 1027 119 0.0221 0.0273 0.2353 0.10 8pd8:A, 8pd8:B, 8pd9:A, 8pdu:A, 8pdu:B
25 8otq:A 1051 82 0.0142 0.0171 0.2195 0.33 8otq:B, 8otw:B, 8xq8:A
26 3s4l:A 197 63 0.0205 0.1320 0.4127 0.38
27 8d49:A 1072 94 0.0213 0.0252 0.2872 0.43
28 8d49:A 1072 72 0.0205 0.0243 0.3611 0.90
29 8d49:A 1072 57 0.0166 0.0196 0.3684 4.9
30 5gan:B 1781 117 0.0244 0.0174 0.2650 2.5 4bgd:A, 5gao:B, 5gap:B, 5nrl:B, 5zwm:D, 5zwo:D
31 8com:G 98 50 0.0134 0.1735 0.3400 2.8 8com:C
32 8ptk:f 4502 179 0.0315 0.0089 0.2235 3.1 8ptk:e
33 7z8f:e 4579 179 0.0315 0.0087 0.2235 3.1 5owo:A, 8pr2:f, 8ptk:m, 8ptk:n, 7z8f:f, 7z8f:m, 7z8f:n, 7z8h:A
34 2f06:A 144 50 0.0126 0.1111 0.3200 6.1 2f06:B
35 2x65:A 334 55 0.0134 0.0509 0.3091 8.0 2x5z:A, 2x5z:B, 2x60:A, 2x60:B, 2x65:B
36 8adl:A 633 51 0.0142 0.0284 0.3529 8.6 8adl:I
37 3d19:A 264 53 0.0134 0.0644 0.3208 9.6 3d19:B, 3d19:C, 3d19:D, 3d19:E, 3d19:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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