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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MRIVINGFGRIGRLVLRQILKRNSPIEVVAINDLVAGDLLTYLFKYDSTHGSFAPQATFSDGCLVMGERKVHFLAEKDVQ
KLPWKDLDVDVVVESTGLFVNRDDVAKHLDSGAKRVLITAPAKGDVPTFVMGVNHQQFDPADVIISNASCTTNCLAPLAK
VLLDNFGIEEGLMTTVHAATATQSVVDGPSRKDWRGGRGAFQNIIPASTGAAKAVGLCLPELKGKLTGMAFRVPVADVSV
VDLTVKLSSATTYEAICEAVKHAANTSMKNIMYYTEEAVVSSDFIGCEYSSVFDAQAGVALNDRFFKLVAWYDNEIGYAT
RIVDLLEYVQENS

The query sequence (length=333) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6ok4:A 334 332 0.9850 0.9820 0.9880 0.0 6ok4:B, 6ok4:C, 6ok4:D, 6wyc:A, 6wyc:B, 6wyc:C, 6wyc:D, 6x2e:A, 6x2e:C, 6x2e:D
2 8oha:B 336 332 0.6036 0.5982 0.6054 2.38e-147 8oha:A, 8oha:C, 8oha:D, 8oha:E, 8oha:F, 8oha:G, 8oha:H
3 4p8r:A 331 331 0.5826 0.5861 0.5861 3.46e-144 4p8r:B, 4p8r:C, 4p8r:D
4 4mvj:B 332 331 0.5916 0.5934 0.5952 2.15e-141 1dc4:A, 1dc4:B, 1dc6:A, 1dc6:B, 1gad:O, 1gad:P, 1gae:O, 1gae:P, 6io6:A, 4mvj:A, 4mvj:C, 4mvj:D, 4mvj:E, 4mvj:F, 4mvj:G, 4mvj:I, 4mvj:J, 4mvj:K, 4mvj:L, 4mvj:M, 4mvj:O, 4mvj:P, 6utm:A, 6utm:B, 6utn:A, 6utn:B, 6uto:A, 6uto:B, 2vyn:A, 2vyn:B, 2vyn:C, 2vyv:A, 2vyv:B, 2vyv:C, 5za0:A
5 7xzg:A 334 334 0.5946 0.5928 0.5928 5.06e-141 7xzg:B, 7xzg:C, 7xzg:D
6 3pym:A 332 332 0.5886 0.5904 0.5904 7.47e-141 3pym:B
7 4lsm:A 331 329 0.5526 0.5559 0.5593 6.85e-137 4lsm:B
8 1ywg:O 337 334 0.5826 0.5757 0.5808 9.19e-137 2b4r:O, 2b4r:P, 2b4r:Q, 2b4r:R, 2b4t:O, 2b4t:P, 2b4t:Q, 2b4t:R, 1ywg:P, 1ywg:Q, 1ywg:R
9 6nlx:C 335 328 0.5706 0.5672 0.5793 1.51e-134 6nlx:B, 6nlx:D, 5ur0:A, 5ur0:B, 5ur0:C, 5ur0:D
10 3h9e:P 337 331 0.5616 0.5549 0.5650 1.42e-132 5c7o:O, 5c7o:P, 3h9e:O, 3pfw:O, 3pfw:P
11 2vyn:D 334 331 0.5556 0.5539 0.5589 3.28e-132 2vyv:D
12 6qun:O 334 334 0.5616 0.5599 0.5599 1.11e-131 6qun:R, 6quq:O, 6quq:R, 4z0h:O, 4z0h:R
13 6m61:O 336 330 0.5616 0.5565 0.5667 4.48e-131 6ade:A, 5ddi:P, 5ddi:R, 5ddi:S, 6iq6:A, 6iq6:B, 6iq6:C, 6iq6:D, 6iq6:E, 1j0x:P, 1j0x:R, 6lgj:A, 6lgj:B, 6lgj:C, 6lgj:D, 6lgk:A, 6lgk:B, 6lgk:C, 6lgm:A, 6lgm:B, 6lgm:C, 6m61:Q, 6m61:P, 4o59:O, 4o59:P, 4o59:R, 4o59:Q, 4o63:P, 4o63:Q, 4o63:R, 8p5f:AAA, 8p5f:DDD, 8p5f:EEE, 8p5f:GGG, 5tso:P, 5tso:R, 5tso:S, 7u5m:A, 7u5m:B, 7u5m:C, 7u5m:D, 1u8f:P, 1u8f:Q, 1u8f:R, 4wnc:O, 4wnc:E, 4wnc:A, 4wnc:B, 4wnc:C, 4wnc:D, 4wni:O, 4wni:A, 4wni:B, 1znq:O, 1znq:P, 1znq:R, 1znq:Q
14 3e5r:O 336 334 0.5556 0.5506 0.5539 1.13e-129 3e5r:A, 3e5r:B, 3e5r:C, 3v1y:O, 3v1y:A, 3v1y:B, 3v1y:C
15 8de5:A 338 333 0.5435 0.5355 0.5435 4.60e-129
16 4k9d:A 338 334 0.5766 0.5680 0.5749 2.53e-128 4k9d:B, 4k9d:C, 4k9d:D, 4k9d:E, 4k9d:F, 4k9d:G, 4k9d:H
17 6px2:A 332 331 0.5826 0.5843 0.5861 3.40e-128 6px2:B, 6px2:C, 6px2:D, 6px2:E, 6px2:F, 6px2:G, 6px2:H
18 1dss:G 333 331 0.5375 0.5375 0.5408 2.71e-126 1dss:R, 1gpd:G, 1gpd:R, 1ihx:A, 1ihx:B, 1ihx:C, 1ihx:D, 1ihy:A, 1ihy:B, 1ihy:C, 1ihy:D, 1szj:G, 1szj:R
19 3cif:A 338 329 0.5616 0.5533 0.5684 7.62e-126 3cif:B, 3cif:C, 3cif:D, 3cps:A, 3cps:B, 8pvf:A, 1vsv:A, 1vsv:B, 1vsv:C, 1vsv:D
20 3gpd:R 334 330 0.5435 0.5419 0.5485 1.01e-125 3gpd:G
21 3sth:C 340 333 0.5706 0.5588 0.5706 2.35e-125 3sth:A, 3sth:B, 3sth:D
22 2i5p:O 309 330 0.5465 0.5890 0.5515 1.24e-121 2i5p:P
23 6m5x:O 334 331 0.5135 0.5120 0.5166 1.68e-120 6m5x:R, 6m5x:P, 6m5x:Q
24 3cmc:O 334 330 0.5105 0.5090 0.5152 3.79e-115 3cmc:P, 3cmc:Q, 3cmc:R, 1dbv:O, 1dbv:P, 1dbv:Q, 1dbv:R, 2dbv:O, 2dbv:P, 2dbv:Q, 2dbv:R, 3dbv:O, 3dbv:P, 3dbv:Q, 3dbv:R, 4dbv:O, 4dbv:P, 4dbv:Q, 4dbv:R, 1gd1:O, 1gd1:P, 1gd1:Q, 1gd1:R, 1npt:O, 1npt:P, 1npt:Q, 1npt:R, 1nq5:O, 1nq5:Q, 1nq5:A, 1nq5:C, 1nqa:O, 1nqa:P, 1nqa:Q, 1nqa:R, 1nqo:O, 1nqo:Q, 1nqo:A, 1nqo:C
25 1hdg:O 332 327 0.5015 0.5030 0.5107 8.62e-113 1hdg:Q
26 6ghr:B 342 332 0.4805 0.4678 0.4819 6.32e-110 4boy:A, 4boy:B, 6gfo:A, 6gfo:B, 6gfo:C, 6gfo:D, 6gfp:A, 6gfp:B, 6gfq:B, 6gfq:A, 6gfr:A, 6gfr:B, 6gg7:B, 6gg7:A, 6ghl:A, 6ghl:D, 6ghl:B, 6ghl:C, 6ghr:D, 6ghr:A, 6ghr:C, 6gve:D, 6gve:A, 6gve:E, 6gve:F, 6gve:I, 6gve:K, 6gve:N, 6gve:O, 3zcx:A, 3zcx:B, 3zdf:B, 3zdf:A
27 1a7k:A 358 348 0.5105 0.4749 0.4885 8.40e-110 1a7k:B, 1a7k:C, 1a7k:D, 1gyp:A, 1gyp:B, 1gyp:C, 1gyp:D, 1gyq:A, 1gyq:B, 1gyq:C, 1gyq:D, 1i32:A, 1i32:B, 1i32:C, 1i32:D, 1i32:E, 1i32:F, 1i33:A, 1i33:B, 1i33:C, 1i33:D, 1i33:E, 1i33:F
28 3dmt:A 359 348 0.4925 0.4568 0.4713 1.38e-108 3dmt:B, 3dmt:C, 3dmt:D, 3ids:D, 1k3t:C, 1ml3:B, 1ml3:C, 1ml3:D, 1qxs:C, 1qxs:D, 1qxs:A, 1qxs:B, 2x0n:A, 2x0n:B, 2x0n:O, 2x0n:P, 2x0n:Q, 2x0n:R
29 3lvf:P 338 336 0.4895 0.4822 0.4851 3.17e-107 3hq4:R, 3hq4:O, 3hq4:P, 3hq4:Q, 3k73:Q, 3k73:O, 3k73:P, 3k73:R, 3k9q:Q, 3k9q:O, 3k9q:P, 3k9q:R, 3ksd:Q, 3ksd:R, 3ksd:O, 3ksd:P, 3ksz:O, 3ksz:P, 3ksz:R, 3ksz:Q, 3kv3:O, 3kv3:Q, 3kv3:R, 3kv3:P, 3l4s:Q, 3l4s:P, 3l4s:O, 3l4s:R, 3l6o:Q, 3l6o:P, 3l6o:R, 3l6o:O, 3lc1:P, 3lc1:R, 3lc1:O, 3lc1:Q, 3lc2:O, 3lc2:Q, 3lc2:R, 3lc2:P, 3lvf:R, 3lvf:O, 3lvf:Q, 5t73:A, 5t73:B, 5t73:C, 5t73:D, 3vaz:P, 3vaz:R, 3vaz:O, 3vaz:Q, 3vaz:B, 3vaz:A
30 5vmt:B 334 332 0.4835 0.4820 0.4849 5.80e-104 5vmt:A, 5vmt:C, 5vmt:D, 5vmt:F, 5vmt:G, 5vmt:H
31 3hja:A 334 334 0.4955 0.4940 0.4940 8.58e-104 3hja:B, 3hja:C, 3hja:D
32 7c5o:O 338 329 0.4865 0.4793 0.4924 1.24e-103 7c5f:O, 7c5f:P, 7c5f:Q, 7c5f:R, 7c5g:O, 7c5g:P, 7c5g:Q, 7c5g:R, 7c5h:O, 7c5h:P, 7c5h:Q, 7c5h:R, 7c5i:O, 7c5i:P, 7c5i:Q, 7c5i:R, 7c5j:O, 7c5j:P, 7c5j:Q, 7c5j:R, 7c5k:O, 7c5k:P, 7c5k:Q, 7c5k:R, 7c5l:O, 7c5l:P, 7c5l:Q, 7c5l:R, 7c5m:O, 7c5m:P, 7c5m:Q, 7c5m:R, 7c5n:O, 7c5n:P, 7c5n:Q, 7c5n:R, 7c5o:P, 7c5o:Q, 7c5o:R, 7c5p:O, 7c5p:P, 7c5p:Q, 7c5p:R, 7c5q:O, 7c5q:P, 7c5q:Q, 7c5q:R, 7c5r:O, 7c5r:P, 7c5r:Q, 7c5r:R, 7c7k:O, 7c7k:P, 7c7k:Q, 7c7k:R
33 7bew:A 330 329 0.4685 0.4727 0.4742 7.33e-103 7bex:A
34 7jwk:C 333 332 0.4745 0.4745 0.4759 2.87e-101 7jwk:A, 7jwk:B, 7jwk:D
35 2ep7:B 339 340 0.4805 0.4720 0.4706 6.69e-101 2ep7:A
36 8br4:A 339 338 0.4985 0.4897 0.4911 1.65e-100 8br4:B, 8br4:C, 8br4:D, 8br4:E, 8br4:F, 8br4:G, 8br4:H, 8br4:I, 8br4:J, 8br4:K, 8br4:L, 8br4:M, 8br4:N, 8br4:O, 8br4:P
37 8hrq:B 336 330 0.4685 0.4643 0.4727 7.46e-98 8hro:A, 8hro:B, 8hrp:A, 8hrp:B, 8hrp:C, 8hrp:D, 8hrp:E, 8hrp:F, 8hrp:G, 8hrp:H, 8hrq:A, 8hrr:A, 8hrr:B, 8hrs:A, 8hrs:B, 8hrs:C, 8hrs:D, 8hrt:A, 8hrt:B, 8hrt:C, 8hrt:D
38 3doc:A 335 325 0.4535 0.4507 0.4646 1.53e-97 3doc:B, 3doc:C, 3doc:D
39 1nbo:O 337 331 0.4745 0.4688 0.4773 2.14e-97 1jn0:O, 1jn0:A, 1jn0:B, 1nbo:A, 1nbo:B, 2pkq:P, 2pkq:R, 2pkq:S, 2pkr:O, 2pkr:R, 2pkr:P, 2pkr:Q, 2pkr:A, 2pkr:B, 2pkr:C, 2pkr:D, 2pkr:H, 2pkr:I, 2pkr:L, 2pkr:M, 7q53:P, 7q53:R, 7q54:R, 7q54:P, 7q54:B, 7q54:D, 7q55:P, 7q55:R, 7q55:B, 7q55:D, 7q55:F, 7q55:H, 7q55:J, 7q55:L, 7q56:J, 7q56:L, 7q56:B, 7q56:D, 7q56:R, 7q56:P, 7q56:H, 7q56:F, 7q57:P, 7q57:R, 7q57:B, 7q57:D, 7q57:H, 7q57:F, 7q57:J, 7q57:L, 7q57:N, 7q57:T, 1rm3:O, 1rm3:A, 1rm3:B, 1rm4:O, 1rm4:A, 1rm4:B, 1rm5:O, 1rm5:A, 1rm5:B
40 3l0d:A 332 326 0.4595 0.4608 0.4693 4.16e-97 3l0d:B
41 6fzi:B 332 331 0.4625 0.4639 0.4653 1.59e-95 6fzi:A, 6fzi:C, 6fzi:D
42 5m6d:A 346 332 0.4505 0.4335 0.4518 9.24e-95 6fzh:A, 6fzh:B, 6ite:P, 6ite:Q, 6ite:R, 6ite:O
43 3b1j:A 338 330 0.4685 0.4615 0.4727 1.05e-94 3b1j:B, 3b1k:A, 3b1k:H, 3b1k:B, 3b1k:G, 3b20:A, 3b20:B, 3b20:O, 3b20:P, 3b20:Q, 3b20:R, 2d2i:A, 2d2i:B, 2d2i:O, 2d2i:P, 2d2i:Q, 2d2i:R, 2duu:A, 2duu:B, 2duu:O, 2duu:P, 2duu:Q, 2duu:R
44 5utm:A 345 333 0.4565 0.4406 0.4565 3.22e-94 5jy6:A, 5jy6:B, 5jy6:C, 5jy6:D, 5jya:A, 5jya:B, 5jya:C, 5jya:D, 5jye:A, 5jye:C, 4qx6:A, 4qx6:B, 4qx6:C, 4qx6:D, 5utl:A, 5utl:B, 5utl:C, 5utl:D, 5utm:B, 5utm:C, 5utm:D, 5v8x:A, 5v8x:B, 5v8x:C, 5v8x:D, 5y37:A, 5y37:B
45 1cer:O 331 330 0.4775 0.4804 0.4818 8.77e-94 1cer:P, 1cer:Q, 1cer:R, 1cer:A, 1cer:B, 1cer:C, 1cer:D, 2g82:O, 2g82:P, 2g82:Q, 2g82:R, 2g82:A, 2g82:B, 2g82:C, 2g82:D, 1vc2:A
46 7www:A 336 334 0.4715 0.4673 0.4701 4.13e-92
47 3k2b:A 337 334 0.4595 0.4540 0.4581 1.62e-89 3k2b:B, 3k2b:C, 3k2b:D, 3k2b:E, 3k2b:F, 3k2b:G, 3k2b:H, 3k2b:O, 3k2b:Q, 6kez:A, 6kez:B, 6kez:C, 6kez:D, 6kez:E, 6kez:F, 6kez:G, 6kez:H, 3qv1:A, 3qv1:D, 3qv1:B, 3qv1:C, 3qv1:F, 3qv1:E, 3rvd:A, 3rvd:D, 3rvd:B, 3rvd:C, 3rvd:O, 3rvd:Q, 3rvd:F, 3rvd:G, 3rvd:E, 3rvd:H
48 5ld5:C 342 340 0.4505 0.4386 0.4412 4.00e-89 5ld5:A, 5ld5:B, 5ld5:D
49 8hmn:D 340 334 0.4565 0.4471 0.4551 2.45e-88 8hmn:A, 8hmn:B, 8hmn:C, 6iqm:A, 6iqm:B, 6iqm:C, 6iqm:D
50 7zq3:R 348 330 0.4655 0.4454 0.4697 7.22e-87 7zq3:O, 7zq4:O, 7zq4:R, 7zqk:O, 7zqk:R
51 3gnq:C 335 327 0.4324 0.4299 0.4404 1.28e-86 3gnq:B, 3gnq:D, 3gnq:E, 3gnq:F, 3gnq:G, 3gnq:H
52 7q54:C 368 335 0.4565 0.4130 0.4537 3.48e-86 2pkq:O, 2pkq:Q, 2pkq:T, 7q53:O, 7q53:Q, 7q54:Q, 7q54:O, 7q54:A, 7q55:O, 7q55:Q, 7q55:A, 7q55:C, 7q55:E, 7q55:G, 7q55:I, 7q55:K, 7q56:K, 7q56:E, 7q56:I, 7q56:A, 7q56:G, 7q56:C, 7q56:Q, 7q56:O, 7q57:O, 7q57:Q, 7q57:A, 7q57:C, 7q57:G, 7q57:E, 7q57:I, 7q57:K, 7q57:M, 7q57:S
53 1obf:O 335 327 0.4264 0.4239 0.4343 8.51e-85 1obf:P
54 5vmt:E 293 328 0.4444 0.5051 0.4512 1.56e-82
55 9iil:A 341 335 0.4294 0.4194 0.4269 3.47e-79 9iil:B, 9iil:C, 9iil:D, 9iim:A, 9iim:C, 9iim:B, 9iim:D, 9ij6:A, 9ij6:C, 9ij6:B, 9ij6:D, 8zn1:A, 8zn1:C, 8zn1:B, 8zn1:D, 8zn4:A, 8zn4:B, 8zn4:C, 8zn4:D, 8zoz:A, 8zoz:C, 8zoz:B, 8zoz:D
56 2xf8:M 327 327 0.3604 0.3670 0.3670 2.89e-69 2xf8:A, 2xf8:C, 2xf8:E, 2xf8:G, 2xf8:I, 2xf8:K, 2xf8:O
57 8jb1:A 468 341 0.3574 0.2543 0.3490 3.82e-58 8jb1:B
58 1ys4:A 348 66 0.0541 0.0517 0.2727 0.25 1ys4:B
59 5kat:A 165 72 0.0691 0.1394 0.3194 0.66 5kau:A, 5kaw:A, 5kcb:A
60 4x2d:A 227 26 0.0420 0.0617 0.5385 0.67
61 3ec7:A 336 42 0.0571 0.0565 0.4524 0.82 3ec7:B, 3ec7:C, 3ec7:D, 3ec7:E, 3ec7:F, 3ec7:G, 3ec7:H
62 5ynv:B 313 34 0.0420 0.0447 0.4118 1.0 5y72:A, 5y72:B, 5y7c:A, 5y7c:B, 5y84:A, 5y84:B, 5ynt:A, 5ynt:B, 5ynu:A, 5ynu:B, 5ynv:A, 5ynw:A, 5ynw:B
63 3pvz:A 372 151 0.1141 0.1022 0.2517 1.3 3pvz:C, 3pvz:D
64 3pvz:B 300 151 0.1141 0.1267 0.2517 1.4
65 5j5d:A 297 73 0.0571 0.0640 0.2603 3.5 3l21:B, 1xxx:A, 1xxx:B, 1xxx:C, 1xxx:D, 1xxx:E, 1xxx:F, 1xxx:G, 1xxx:H
66 4gme:A 403 73 0.0661 0.0546 0.3014 4.9 4gme:C, 3vcn:A, 3vcn:C
67 3hsk:A 358 237 0.1562 0.1453 0.2194 5.4
68 7pci:A 345 137 0.1141 0.1101 0.2774 7.1 7pcc:A, 7pcc:B, 7pce:A, 7pcg:A, 7pcg:B, 7pcl:A, 7pcl:B, 7pcm:A, 7pcm:B, 7pcn:A, 7pcn:B, 7pco:A, 7pco:B, 7pct:A, 7pct:B
69 6qlh:A 208 27 0.0390 0.0625 0.4815 9.3 6qli:A, 6qlj:A, 6qlk:A, 6qll:A, 6qlv:A, 6qlv:B, 6qlv:C, 6qlv:D, 6qlv:H, 6qlv:E, 6qlv:F, 6qlv:K, 6qlv:G, 6qlv:I, 6qlv:J, 6qlv:L, 4zaf:A, 4zag:A, 4zal:A, 4zan:A, 4zav:A, 4zaw:A, 4zax:A, 4zay:A, 4zaz:A, 3zqu:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218