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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MQTLLALNWKMNKTPTEARSWAEELTTKYAPAEGVDLAVLAPALDLSALAANLPAGIAFGGQDVSAHESGAYTGEISAAM
LKDAGASCVVVGHSERREYHDESDATVAAKARQAQANGLLPIVCVGENLDVRERGEHVPQTLAQLRGSLEGVGADVVVAY
EPVWAIGTGKTATADDAEELAAAIRGALREQYGARAEGIRVLYGGSVKPENIAEICGKPNVNGALVGGASLKVPDVLGML
DALR

The query sequence (length=244) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4y90:A 244 244 1.0000 1.0000 1.0000 4.77e-178 4y90:B, 4y90:C, 4y90:D
2 3tao:A 256 242 0.5082 0.4844 0.5124 5.35e-66
3 3uwv:A 255 254 0.4221 0.4039 0.4055 6.13e-58 3uwu:A, 3uwu:B, 3uwv:B, 3uww:A, 3uww:B, 3uwz:A, 3uwz:B
4 1btm:A 251 249 0.4221 0.4104 0.4137 2.18e-57 1btm:B, 2btm:A, 2btm:B
5 1aw1:A 255 231 0.4016 0.3843 0.4242 1.15e-54 1aw1:B, 1aw1:D, 1aw1:E, 1aw1:G, 1aw1:H, 1aw1:J, 1aw1:K
6 8w06:B 251 240 0.4221 0.4104 0.4292 3.33e-54 8v09:A, 8v0a:B, 8w06:A, 8w06:C, 8w06:D, 8w06:E, 8w06:F, 8w06:G, 8w06:H
7 6nee:B 252 242 0.4098 0.3968 0.4132 7.71e-52 6nee:A
8 6bve:A 242 238 0.4016 0.4050 0.4118 1.05e-51 6bve:B
9 4y96:A 250 247 0.4221 0.4120 0.4170 1.62e-50 4y96:B
10 6oog:A 252 243 0.3934 0.3810 0.3951 1.27e-48
11 5zfx:B 248 242 0.4016 0.3952 0.4050 5.31e-48
12 4mva:A 255 231 0.3852 0.3686 0.4069 7.28e-47 4mva:B
13 4bi7:A 256 244 0.3934 0.3750 0.3934 2.53e-46 4bi6:A, 3pf3:A
14 1amk:A 250 248 0.3852 0.3760 0.3790 6.57e-46 7abx:A, 7az3:A, 7az4:A, 7az9:A, 7aza:A, 1if2:A, 1n55:A, 1qds:A, 2vxn:A, 2y61:A, 2y62:A, 2y63:A
15 1hti:B 248 238 0.3934 0.3871 0.4034 7.00e-46 4owg:A, 4owg:B, 4poc:B, 4pod:B, 1r2r:B, 7rde:B, 7t0q:A, 6up5:B, 6upf:A, 6upf:B, 7uxv:A, 7uxv:B
16 4ff7:A 247 240 0.3893 0.3846 0.3958 1.59e-45 4ff7:B, 7tim:A, 7tim:B, 2ypi:A, 2ypi:B, 3ypi:A, 3ypi:B
17 5eyw:A 244 239 0.3852 0.3852 0.3933 2.14e-45 5eyw:B
18 1ssg:A 247 240 0.3975 0.3927 0.4042 8.28e-45 1ssg:B, 1su5:A, 1su5:B, 1sw0:A, 1sw0:B, 1sw3:A, 1sw3:B, 1sw7:A, 1sw7:B, 1tpb:1, 1tpb:2, 1tpc:1, 1tpc:2, 1tph:1, 1tph:2, 1tpu:A, 1tpu:B, 1tpv:A, 1tpv:B, 1tpw:A, 1tpw:B
19 5gzp:A 246 232 0.3279 0.3252 0.3448 3.22e-43 5gv4:A, 5gzp:B, 1lyx:A, 1lzo:B, 1lzo:D, 1m7p:A, 1m7p:B, 1o5x:A, 1o5x:B, 3pvf:A, 1woa:A, 1woa:B, 1woa:C, 1woa:D, 1wob:A, 1wob:B, 1wob:C, 1wob:D
20 6ooi:C 255 235 0.3730 0.3569 0.3872 1.31e-42 6ooi:A, 6ooi:B, 6ooi:D, 6ooi:E, 6ooi:F, 6ooi:G, 6ooi:H
21 1ci1:B 249 181 0.3402 0.3333 0.4586 8.39e-42
22 1ag1:T 249 249 0.3934 0.3855 0.3855 2.54e-39 5i3h:B, 5i3i:A, 5i3i:B, 5i3i:C, 5i3i:D, 5i3k:B, 5i3k:C, 5i3k:D, 1iig:B, 2j27:A, 2j27:B, 1kv5:A, 1kv5:B, 4tim:B, 6tim:B, 1trd:B, 1tsi:A, 2v2c:A
23 2y6z:A 256 171 0.3115 0.2969 0.4444 1.23e-33 1ml1:A, 1ml1:C, 1ml1:E, 1ml1:G, 1ml1:I, 1ml1:K, 4pc8:A, 1tti:A, 1ttj:A, 2v2h:A, 2v2h:B, 2v2h:C, 2vek:B, 2vel:A, 2vel:B, 2vem:A, 2vem:B, 2wsr:A, 2x1r:A, 2x1r:B, 2x1s:A, 2x1s:B, 2x1t:B
24 2jgq:A 231 237 0.2787 0.2944 0.2869 5.99e-28 2jgq:B
25 5csr:C 220 133 0.1557 0.1727 0.2857 6.39e-07 5csr:A, 5csr:B, 5csr:D, 5css:A, 5css:B, 5css:C, 5css:D
26 1hg3:A 224 124 0.1311 0.1429 0.2581 6.50e-04 1hg3:B, 1hg3:C, 1hg3:D, 1hg3:E, 1hg3:F, 1hg3:G, 1hg3:H
27 1w0m:A 225 140 0.1639 0.1778 0.2857 0.095 1w0m:B, 1w0m:C, 1w0m:D, 1w0m:E, 1w0m:F, 1w0m:G, 1w0m:H
28 1wza:A 488 110 0.1189 0.0594 0.2636 1.4
29 7zm7:A 711 137 0.1475 0.0506 0.2628 2.7 7zmb:A, 7zmg:A
30 1rcq:A 357 62 0.0779 0.0532 0.3065 3.3
31 6ywe:i 124 53 0.0820 0.1613 0.3774 3.9 6yws:i, 6ywv:i, 6ywx:i, 6ywy:i
32 1i7q:A 517 63 0.0820 0.0387 0.3175 6.5 1i7q:C, 1i7s:A, 1i7s:C
33 4rk9:A 384 54 0.0656 0.0417 0.2963 7.2 4rk9:B
34 4wtv:B 426 45 0.0697 0.0399 0.3778 7.4
35 3j7a:M 138 17 0.0369 0.0652 0.5294 8.1 3jbn:M, 3jbo:M, 3jbp:M, 6okk:M, 8tpu:SM

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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