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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MPIIEQVRAREILDSRGNPTVEVEVALIDGTFARAAVPSGASTGEHEAVELRDGGDRYGGKGVQKAVQAVLDEIGPAVIG
LNADDQRLVDQALVDLDGTPDKSRLGGNAILGVSLAVAKAAADSAELPLFRYVGGPNAHILPVPMMNILNGGAHADTAVD
IQEFMVAPIGAPSFVEALRWGAEVYHALKSVLKKEGLSTGLGDEGGFAPDVAGTTAALDLISRAIESAGLRPGADVALAL
DAAATEFFTDGTGYVFEGTTRTADQMTEFYAGLLGAYPLVSIEDPLSEDDWDGWAALTASIGDRVQIVGDDIFVTNPERL
EEGIERGVANALLVKVNQIGTLTETLDAVTLAHHGGYRTMISHRSGETEDTMIADLAVAIGSGQIKTGAPARSERVAKYN
QLLRIEEALGDAARYAGDLAFPRFAE

The query sequence (length=426) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7cll:C 426 426 1.0000 1.0000 1.0000 0.0 7ckp:A, 7clk:A, 7cll:A, 7cll:B, 7cll:D, 7dlr:A, 7e4f:A, 7e51:A, 7e51:B, 7e51:C, 7e51:D, 7e51:E, 7e51:F, 7e51:G, 7e51:H, 6l7d:A
2 1iyx:A 431 424 0.5822 0.5754 0.5849 0.0 1iyx:B
3 5j04:A 424 415 0.6103 0.6132 0.6265 3.11e-180 5j04:B, 4rop:A
4 4z17:A 424 421 0.5986 0.6014 0.6057 7.62e-176 4yws:A, 4z17:B, 4z1y:A, 4z1y:B
5 5bof:A 434 430 0.5751 0.5645 0.5698 3.30e-174 5boe:A, 5boe:B, 5bof:B
6 6nb2:B 424 404 0.5587 0.5613 0.5891 5.85e-172 6nb2:A, 6nbm:A, 6nbm:B
7 4mks:A 400 420 0.5610 0.5975 0.5690 4.72e-170 4mks:B
8 1w6t:B 430 429 0.5610 0.5558 0.5571 1.44e-169 1w6t:A
9 3uj2:A 423 422 0.5587 0.5626 0.5640 1.22e-161 3uj2:B, 3uj2:C, 3uj2:D, 3uj2:E, 3uj2:F, 3uj2:G, 3uj2:H
10 6bfy:A 439 425 0.5516 0.5353 0.5529 3.19e-156 6bfy:B, 6bfy:C, 6bfy:F, 6bfy:D, 6bfy:E, 6bfz:A, 6bfz:B, 6bfz:E, 6bfz:F, 6bfz:D, 6bfz:C, 6d3q:A, 6d3q:C, 6d3q:B, 6d3q:E, 6d3q:F, 6d3q:D, 1e9i:A, 1e9i:B, 1e9i:C, 1e9i:D, 2fym:A, 2fym:C, 2fym:D, 2fym:F, 3h8a:A, 3h8a:B, 3h8a:C, 3h8a:D, 6npf:A, 6npf:B, 6npf:C, 6npf:D, 6npf:F, 6npf:E, 5ohg:A, 5ohg:B, 5ohg:H, 5ohg:I
11 6o4n:A 422 428 0.5423 0.5474 0.5397 2.61e-155 6o4n:B, 8w21:A, 8w21:B, 8w21:C, 8w21:E, 8w21:G, 8w21:H
12 3qn3:A 415 406 0.5258 0.5398 0.5517 6.00e-151 3qn3:B, 3qn3:C, 3qn3:D
13 3tqp:A 418 420 0.5540 0.5646 0.5619 6.78e-150 3tqp:B
14 5eu9:C 436 428 0.5423 0.5298 0.5397 7.48e-150 2akm:A, 2akm:B, 2akz:A, 2akz:B, 5eu9:A, 5eu9:B, 5eu9:D, 5eu9:E, 5eu9:F, 5eu9:G, 5eu9:H, 5idz:A, 5idz:B, 7mbh:A, 7mbh:B, 5td9:A, 5td9:B, 1te6:A, 1te6:B, 5tij:A, 5tij:B, 3ucc:A, 3ucc:B, 3ucd:A, 3ucd:B, 3uje:A, 3uje:B, 3ujf:A, 3ujf:B, 3ujr:A, 3ujr:B, 3ujs:A, 3ujs:B, 4za0:A, 4za0:B, 4zcw:A, 4zcw:B
15 4yws:B 393 420 0.5610 0.6081 0.5690 1.67e-149
16 2xsx:B 435 430 0.5235 0.5126 0.5186 2.67e-145 2xsx:A
17 7vrd:A 439 430 0.5469 0.5308 0.5419 4.39e-144 7vrd:B, 7vrd:C, 7vrd:D
18 3b97:C 433 429 0.5117 0.5035 0.5082 1.60e-143 3b97:A, 3b97:B, 3b97:D, 2psn:A, 2psn:B, 2psn:C, 2psn:D
19 1pdz:A 433 430 0.5117 0.5035 0.5070 3.70e-143 8uel:A, 8uel:B
20 3qtp:B 439 431 0.5188 0.5034 0.5128 2.29e-142 3qtp:A
21 4g7f:A 419 428 0.5023 0.5107 0.5000 2.66e-138
22 2xgz:A 437 433 0.5235 0.5103 0.5150 9.09e-138 2al1:A, 2al1:B, 2al2:A, 2al2:B, 1ebg:A, 1ebg:B, 1ebh:A, 1ebh:B, 1els:A, 4enl:A, 5enl:A, 6enl:A, 7enl:A, 1l8p:A, 1l8p:B, 1l8p:C, 1l8p:D, 1nel:A, 1one:A, 1one:B, 2one:A, 2one:B, 1p43:A, 1p43:B, 1p48:A, 1p48:B, 2xgz:B, 2xh0:A, 2xh0:B, 2xh0:C, 2xh0:D, 2xh2:A, 2xh2:D, 2xh2:B, 2xh2:C, 2xh4:A, 2xh4:B, 2xh4:C, 2xh4:D, 2xh7:A, 2xh7:B
23 2ptx:A 431 424 0.5094 0.5035 0.5118 3.35e-137 1oep:A, 2pty:A, 2ptz:A, 2pu0:A, 2pu1:A
24 7rhw:A 437 432 0.5352 0.5217 0.5278 9.11e-135 7rhv:A, 7rhv:B, 7rhw:B, 7ri0:A, 7ri0:B
25 2ptw:A 406 418 0.4953 0.5197 0.5048 1.64e-133
26 7ugh:A 436 426 0.4765 0.4656 0.4765 2.09e-116 7ugh:B
27 3r25:B 399 99 0.0681 0.0727 0.2929 0.082 3r25:A, 3r25:C, 3r25:D, 3r25:E, 3r25:F, 3r25:G, 3r25:H, 3sbf:A, 3sbf:B, 3sbf:C, 3sbf:D
28 4gir:B 411 91 0.0634 0.0657 0.2967 0.46 4ggh:A, 4ggh:B, 4ggh:C, 4ggh:D, 4gir:A, 4gir:C, 4gir:D, 4gis:A, 4gis:B
29 4hnl:A 401 71 0.0446 0.0474 0.2676 0.82
30 3tji:A 399 78 0.0516 0.0551 0.2821 1.5 3tji:B, 3tji:C, 3tji:D
31 4h83:F 368 81 0.0587 0.0679 0.3086 3.1 4h83:A, 3no1:A, 3no1:B, 3no1:C, 3no1:D, 3no1:E, 3no1:F
32 3gy1:B 388 72 0.0493 0.0541 0.2917 3.5 3gy1:A, 3s47:A, 3s47:B
33 2vhf:A 341 44 0.0329 0.0411 0.3182 4.5 2vhf:B
34 3cb3:A 373 101 0.0657 0.0751 0.2772 7.6 3cb3:B, 3cb3:C, 3cb3:D, 2og9:A, 2og9:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218