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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MLKAVILIGGPQKGTRFRPLSFEVPKPLFPVAGVPMIQHHIEACAQVPGMQEILLIGFYQPDEPLTQFLEAAQQEFNLPV
RYLQEFAPLGTGGGLYHFRDQILAGSPEAFFVLNADVCSDFPLSAMLEAHRRQRHPFLLLGTTANRTQSLNYGCIVENPQ
THEVLHYVEKPSTFISDIINCGIYLFSPEALKPLRDVFQRNQQGTIRLEQDVFSALAGQGQIYVHLTDGIWSQIKSAGSA
LYASRLYLSRYQDTHPERLAKHTPGGPWIRGNVYIHPTAKVAPSAVLGPNVSIGKGVTVGEGVRLRESIVLHGATLQEHT
CVLHSIVGWGSTVGRWARVEGTPSDPNPNDPRARMDSESLFKDGKLLPAITILGCRVRIPAEVLILNSIVLPHKELSRSF
TNQIIL

The query sequence (length=406) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7d72:A 407 407 1.0000 0.9975 0.9975 0.0 7d72:B, 7d72:C, 7d72:D, 7d73:A, 7d73:B, 7d73:C, 7d73:D, 7d74:A, 7d74:D, 7d74:B, 7d74:C
2 7x8k:B 367 399 0.3448 0.3815 0.3509 4.52e-72 7x8k:A, 7x8k:D
3 7d72:K 360 398 0.3300 0.3722 0.3367 1.34e-64 7d72:I, 7d72:E, 7d72:F, 7d72:G, 7d72:H, 7d72:J, 7d72:L, 7d73:E, 7d73:F, 7d73:G, 7d73:I, 7d73:J, 7d73:K, 7d73:L, 7d73:H, 7d74:E, 7d74:F, 7d74:G, 7d74:H, 7d74:I, 7d74:J, 7d74:K, 7d74:L
4 7whs:A 366 397 0.3030 0.3361 0.3098 4.89e-57 7whs:B, 7whs:C, 7whs:D, 7whs:E, 7whs:F, 7wht:A, 7wht:B, 7wht:C, 7wht:D, 7wht:E, 7wht:F
5 4y7u:A 224 245 0.1650 0.2991 0.2735 3.92e-14 4y7v:A
6 2ggq:A 401 343 0.1823 0.1845 0.2157 9.26e-13 5z09:A, 5z09:B, 5z09:C, 5z09:D
7 1hm8:A 458 352 0.2167 0.1921 0.2500 9.72e-12 4aaw:A, 4ac3:A, 1g97:A, 1hm8:B, 1hm9:A, 1hm9:B, 7kr9:A
8 6jlz:I 430 417 0.2266 0.2140 0.2206 1.91e-10
9 3d8v:A 478 354 0.2389 0.2029 0.2740 5.35e-09 3dj4:A, 4g3p:A, 4g3q:A, 4g3s:A, 4g87:A, 6ge9:A, 4hcq:A, 4k6r:A, 2qkx:A, 3spt:A, 3st8:A
10 4e1k:A 450 354 0.2143 0.1933 0.2458 2.03e-08 4knr:A, 4knx:A, 4kpx:A, 4kpz:A, 4kql:A, 2v0i:A, 2v0j:A, 2v0k:A, 2v0l:A, 2vd4:A, 2w0v:A, 2w0w:A
11 6jq8:A 225 129 0.0936 0.1689 0.2946 4.84e-08
12 2oi6:B 452 352 0.2118 0.1903 0.2443 1.18e-06 4aa7:A, 4aa7:B, 1fwy:A, 1fwy:B, 1hv9:A, 1hv9:B, 2oi5:A, 2oi5:B, 2oi6:A, 2oi7:A, 2oi7:B, 3twd:A, 3twd:B
13 3foq:A 439 349 0.2192 0.2027 0.2550 2.40e-06
14 3hl3:A 246 196 0.1133 0.1870 0.2347 2.41e-06 4ecm:A
15 5ify:A 293 233 0.1305 0.1809 0.2275 2.70e-06 5ify:B, 5ify:C, 5ify:D, 5ify:E, 5ify:F
16 1h5s:B 291 232 0.1502 0.2096 0.2629 3.04e-06 1h5r:A, 1h5r:B, 1h5r:C, 1h5r:D, 1h5s:A, 1h5s:D, 1h5s:C, 1h5t:A, 1h5t:D, 1h5t:B, 1h5t:C, 1iim:A, 1iim:B, 1iin:A, 1iin:B, 1iin:C, 1iin:D, 1mp3:A, 1mp3:B, 1mp4:A, 1mp4:B, 1mp5:A, 1mp5:B, 1mp5:C, 1mp5:D, 3pkp:A, 3pkp:B, 3pkp:C, 3pkp:D, 3pkp:I, 3pkp:J, 3pkp:K, 3pkp:L, 3pkq:A, 3pkq:B, 3pkq:C, 3pkq:D
17 4b2x:B 302 237 0.1552 0.2086 0.2658 7.55e-06 4arw:A, 4arw:B, 4arw:C, 4arw:D, 4asj:A, 4asj:B, 4asj:C, 4asj:D, 4asy:A, 4asy:B, 4asy:C, 4asy:D, 4b2w:A, 4b2w:B, 4b2w:C, 4b2w:D, 4b2x:A, 4b2x:C, 4b2x:D, 4b3u:A, 4b3u:B, 4b3u:C, 4b3u:D, 4b42:A, 4b42:B, 4b42:C, 4b42:D, 4b4b:A, 4b4b:B, 4b4b:C, 4b4b:D, 4b4g:A, 4b4g:B, 4b4g:C, 4b4g:D, 4b4m:A, 4b4m:B, 4b4m:C, 4b4m:D, 4b5b:A, 4b5b:B, 4b5b:C, 4b5b:D, 5fts:A, 5fts:B, 5fts:C, 5fts:D, 5ftv:A, 5ftv:B, 5ftv:C, 5ftv:D, 5fu0:A, 5fu0:B, 5fu0:C, 5fu0:D, 5fu8:A, 5fu8:B, 5fu8:C, 5fu8:D, 5fuh:A, 5fuh:B, 5fuh:C, 5fuh:D, 1fxo:A, 1fxo:C, 1fxo:B, 1fxo:D, 1fxo:E, 1fxo:H, 1fxo:F, 1fxo:G, 5fye:A, 5fye:B, 5fye:C, 5fye:D, 1g0r:A, 1g0r:B, 1g0r:C, 1g0r:D, 1g0r:E, 1g0r:G, 1g0r:H, 1g1l:A, 1g1l:C, 1g1l:B, 1g1l:D, 1g1l:E, 1g1l:H, 1g1l:F, 1g1l:G, 1g23:A, 1g23:B, 1g23:C, 1g23:D, 1g23:E, 1g23:F, 1g23:G, 1g23:H, 1g2v:A, 1g2v:C, 1g2v:B, 1g2v:D, 1g2v:E, 1g2v:G, 1g2v:F, 1g2v:H, 1g3l:A, 1g3l:C, 1g3l:B, 1g3l:D, 6t37:A, 6t37:B, 6t37:C, 6t37:D, 6t38:A, 6t38:B, 6t38:C, 6t38:D, 6tqg:A, 6tqg:B, 6tqg:C, 6tqg:D, 3zlk:A, 3zlk:B, 3zlk:C, 3zlk:D, 3zll:A, 3zll:B, 3zll:C, 3zll:D
18 1lvw:A 295 196 0.1158 0.1593 0.2398 1.20e-05 1lvw:B, 1lvw:C, 1lvw:D
19 1jyl:A 228 115 0.0813 0.1447 0.2870 1.35e-05 1jyl:B, 1jyl:C, 1jyl:D
20 4ho9:A 294 225 0.1256 0.1735 0.2267 2.45e-05 4ho3:A, 4ho4:A, 4ho5:A, 4ho5:B, 4ho6:A, 4ho8:A, 4ho8:B, 4ho8:C, 4ho8:D, 4ho9:B, 4hoc:A, 4hoc:B
21 2ux8:G 288 223 0.1379 0.1944 0.2511 3.31e-05 2ux8:B, 2ux8:C, 2ux8:D, 2ux8:E, 2ux8:F
22 6n0u:A 295 195 0.1108 0.1525 0.2308 5.23e-05 6n0u:B, 6n0u:C, 6n0u:D
23 4fce:A 441 351 0.2069 0.1905 0.2393 2.66e-04
24 1wvc:A 254 264 0.1379 0.2205 0.2121 2.84e-04 1tzf:A
25 1mc3:A 291 206 0.1281 0.1787 0.2524 3.75e-04 1mc3:B
26 6r8u:A 425 243 0.1256 0.1200 0.2099 0.005 5l6s:C, 5l6s:G, 5l6s:I, 5l6s:L, 5l6v:A, 5l6v:E, 5l6v:G, 5l6v:H, 5l6v:J, 5l6v:K, 5l6v:N, 5l6v:B, 5l6v:C, 5l6v:D, 5l6v:F, 5l6v:L, 5l6v:M, 5l6v:O, 5l6v:P, 6r8b:D, 6r8b:B, 6r8b:A, 6r8b:C, 6r8u:B, 6r8u:D, 6r8u:C, 6shj:D, 6shj:A, 6shj:B, 6shj:C, 6shn:D, 6shn:C, 6shq:A, 6shq:D, 6shq:C, 6shq:B, 6si8:A, 6si8:B, 6si8:D, 6si8:C
27 4m99:A 206 55 0.0443 0.0874 0.3273 0.005 4m99:B, 4m99:C
28 6b5e:B 286 239 0.1379 0.1958 0.2343 0.007 6b5e:A, 6b5e:C, 6b5e:D, 6b5e:E, 6b5e:F, 6b5e:G, 6b5e:H, 6b5k:A, 6b5k:B
29 4eqy:G 260 82 0.0616 0.0962 0.3049 0.026
30 3juk:A 265 29 0.0296 0.0453 0.4138 0.064 3juk:B, 3juk:C, 3juk:D
31 5l6v:I 400 208 0.1133 0.1150 0.2212 0.069
32 8f73:E 281 43 0.0394 0.0569 0.3721 0.077 8f73:A, 8f73:B, 8f73:C, 8f73:D, 8f73:F, 8f73:G, 8f73:H
33 5i1f:A 290 54 0.0468 0.0655 0.3519 0.11
34 5ve7:A 282 54 0.0493 0.0709 0.3704 0.12
35 2ux8:A 255 55 0.0468 0.0745 0.3455 0.15 2ux8:H
36 3ixc:A 166 158 0.0961 0.2349 0.2468 0.47
37 7okc:A 264 54 0.0468 0.0720 0.3519 0.49 2aq9:A, 6hy2:X, 4j09:A, 2jf3:A, 6p9p:A, 6p9q:A, 6p9r:A, 6p9s:A, 6p9t:A, 2qia:A, 2qiv:X
38 7aqq:y 268 84 0.0542 0.0821 0.2619 0.51 7ar7:y, 7ar8:y, 7arb:y, 8bef:y, 8bpx:y, 8bq5:y, 8bq6:y
39 6k8d:A 290 54 0.0443 0.0621 0.3333 0.62 6ikz:B, 6k8d:B, 6k8d:C, 6k8d:D, 6knj:A, 6knj:B, 6knl:A, 6knl:B
40 1h7h:A 245 28 0.0345 0.0571 0.5000 0.67 1gq9:A, 1gq9:B, 1gqc:A, 1gqc:B, 1h7f:B, 1h7g:B, 1h7h:B, 1h7t:B
41 4ihh:E 340 65 0.0517 0.0618 0.3231 0.67 4ihf:D, 4ihf:E, 4ihf:F, 4ihf:A, 4ihf:B, 4ihf:C, 4ihg:E, 4ihg:C, 4ihg:B, 4ihg:D, 4ihh:A, 4ihh:C, 4ihh:B, 4ihh:D, 4ihh:F, 6p83:A, 6p83:C, 6p83:B, 6p84:A, 6p84:C, 6p84:B, 6p85:A, 6p85:C, 6p85:B, 6p86:A, 6p86:C, 6p86:B, 6p87:A, 6p87:C, 6p87:B, 6p88:A, 6p88:C, 6p88:B, 6p89:A, 6p89:C, 6p89:B, 6p8a:A, 6p8a:C, 6p8a:B, 6p8b:A, 6p8b:C, 6p8b:B
42 6k0w:A 528 44 0.0369 0.0284 0.3409 0.89
43 3p47:A 270 76 0.0591 0.0889 0.3158 0.97 3q1x:A
44 6k0w:B 499 44 0.0369 0.0301 0.3409 1.0
45 6k0w:D 435 44 0.0369 0.0345 0.3409 1.2 6k0w:C
46 3bss:A 194 108 0.0616 0.1289 0.2315 1.2 3bsy:A, 3bsy:C, 3bsy:B, 5t2y:A, 5t2y:B, 5tyh:A, 2vhe:A, 2vhe:B
47 3pmo:A 357 97 0.0739 0.0840 0.3093 1.4 6uec:A
48 6ive:A 168 77 0.0616 0.1488 0.3247 1.4 6ive:B, 6ive:C, 6ive:D, 6ive:E, 6ive:F
49 8a5a:U 690 61 0.0369 0.0217 0.2459 1.9 8a5o:U, 4am7:A, 4am7:B
50 4r37:A 255 125 0.0616 0.0980 0.2000 2.5
51 8b6d:A 291 66 0.0468 0.0653 0.2879 2.8 8b68:A, 8b6d:B
52 6sc4:B 178 112 0.0567 0.1292 0.2054 3.3 6sc4:A, 6sc4:C, 6sc4:D, 6sc4:E
53 2pa4:B 299 25 0.0320 0.0435 0.5200 4.0 2pa4:A, 2pa4:C, 2pa4:D
54 6jly:E 414 69 0.0567 0.0556 0.3333 4.3 6jly:F, 6jlz:E, 6jlz:F
55 8e73:G2 258 128 0.0862 0.1357 0.2734 4.5 6x89:G2
56 6j61:A 242 56 0.0394 0.0661 0.2857 4.6 6j61:B, 6j61:D, 6j61:C
57 8bef:x 210 65 0.0542 0.1048 0.3385 4.9 8bpx:x, 8bq5:x, 8bq6:x
58 3i3a:A 259 64 0.0443 0.0695 0.2812 6.6 3i3a:B, 3i3a:C, 3i3x:A, 3i3x:B, 3i3x:C
59 5hvm:B 452 49 0.0443 0.0398 0.3673 6.6 5hvm:A
60 7tbc:A 338 44 0.0345 0.0414 0.3182 7.6 8dsr:A, 8dsr:B
61 4n27:A 175 47 0.0394 0.0914 0.3404 7.8 4n27:B, 4n27:C, 4n27:D, 4n27:E, 4n27:F
62 4eaa:A 210 51 0.0345 0.0667 0.2745 8.3 4ea7:A, 4ea8:A, 4ea9:A, 4eab:A
63 8bn0:A 342 39 0.0320 0.0380 0.3333 8.3 8bai:A, 8bai:B, 8bai:C, 8bai:D, 8baz:A, 8baz:B, 8bb0:A, 8bb0:B, 8bmy:A, 8bmy:B, 8bmz:A, 8bmz:B
64 7ojp:Z 261 41 0.0369 0.0575 0.3659 9.5 5dep:A, 5dep:B, 5dep:D, 5dep:E, 5dep:F, 5dg3:A, 5dg3:B, 5dg3:C, 5dg3:D, 5dg3:E, 7oj6:A, 7oj6:B, 7oj6:C, 7ojp:A, 7ojp:B, 7ojp:C, 7ojp:D, 7ojp:E, 7ojp:F, 7ojp:G, 7ojp:H, 7ojp:I, 7ojp:J, 7ojp:K, 7ojp:L, 7ojp:M, 7ojp:N, 7ojp:O, 7ojp:P, 7ojp:Q, 7ojp:R, 7ojp:S, 7ojp:T, 7ojp:U, 7ojp:V, 7ojp:W, 7ojp:X, 7ojp:Y, 7ojp:a, 7ojp:b, 7ojp:c, 7ojp:d, 7ojq:A, 7ojq:B, 7ojq:C, 7ojw:A, 7ojw:B, 7ojw:C, 7ojy:A, 7ojy:B, 7ojy:C, 7ok1:A, 7ok1:B, 7ok1:C, 7ok2:1, 7ok2:Y, 7ok2:Z, 7ok2:2, 7ok2:4, 7ok2:3, 7ok2:A, 7ok2:B, 7ok2:C, 7ok2:D, 7ok2:E, 7ok2:F, 7ok2:G, 7ok2:I, 7ok2:H, 7ok2:J, 7ok2:L, 7ok2:K, 7ok2:M, 7ok2:N, 7ok2:O, 7ok2:P, 7ok2:Q, 7ok2:R, 7ok2:S, 7ok2:T, 7ok2:U, 7ok2:V, 7ok2:X, 7ok2:W, 7oka:A, 7oka:C, 7oka:B, 7oka:D, 7oka:E, 7oka:F, 7oka:G, 7oka:H, 7oka:I, 7oka:M, 7oka:N, 7oka:O, 7oka:J, 7oka:K, 7oka:L, 7oka:P, 7oka:Q, 7oka:R, 7oka:S, 7oka:T, 7oka:U, 7oka:V, 7oka:W, 7oka:X, 7oka:Y, 7oka:Z, 7oka:a, 7oka:b, 7oka:d, 7oka:c, 7okb:A, 7okb:B, 7okb:C, 7okb:D, 7okb:E, 7okb:F, 7okb:G, 7okb:H, 7okb:I, 7okb:M, 7okb:N, 7okb:O, 7okb:J, 7okb:K, 7okb:L, 7okb:P, 7okb:Q, 7okb:R, 7okb:S, 7okb:T, 7okb:U, 7okb:V, 7okb:W, 7okb:X, 7okb:Y, 7okb:Z, 7okb:a, 7okb:b, 7okb:c, 7okb:d, 7t5r:A, 7t5r:B, 7t5r:C, 7t5r:D, 7t5r:F, 7t5r:E, 7t5s:A, 7t5s:B, 7t5s:C, 7t5s:D, 7t5s:F, 7t5s:E, 7t5x:A, 7t5x:B, 7t5x:C, 7t5x:D, 7t5x:F, 7t5x:E, 7t5z:A, 7t5z:B, 7t5z:C, 7t5z:D, 7t5z:E, 7t5z:F, 7t60:A, 7t60:B, 7t60:C, 7t60:D, 7t60:F, 7t60:E, 7t61:A, 7t61:B, 7t61:C, 7t61:D, 7t61:E, 7t61:F, 6uee:A, 6uee:C, 6uee:B, 6uee:D, 6uee:E, 6uee:F, 6ueg:A, 6ueg:C, 6ueg:B, 6ueg:D, 6ueg:E, 6ueg:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218