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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKTLSPAVITLLWRQDAAEFYFSRLSHLPWAMLLHSGYADHPYSRFDIVVAEPICTLTTFGKETVVSESEKRTTTTDDPL
QVLQQVLDRADIRPTHNEDLPFQGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRHTVSLLSHNDV
NARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAP
FSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVLVSTITAQLPEQLH
ASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMDTSITIRTLTAINGQIFCSAGGGIVADSQE
EAEYQETFDKVNRILKQLEK

The query sequence (length=420) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1k0e:A 437 437 0.9952 0.9565 0.9565 0.0 1k0g:A
2 1k0g:B 415 418 0.9857 0.9976 0.9904 0.0 1k0e:B
3 7pi1:DDD 459 422 0.3119 0.2854 0.3104 3.40e-65 7pi1:AAA, 7pi1:BBB, 7pi1:CCC, 7qu9:A, 7qu9:B, 7qu9:C
4 5cwa:A 505 457 0.3429 0.2851 0.3151 6.25e-54
5 7bvd:A 499 452 0.3357 0.2826 0.3119 1.40e-53
6 8hx9:A 632 412 0.2976 0.1978 0.3034 9.12e-45
7 8hx8:A 673 409 0.2976 0.1857 0.3056 1.39e-44 8hx6:A, 8hx6:B, 8hx7:A, 8hx7:B, 8hx8:B, 8hx9:B
8 1i1q:A 512 395 0.2833 0.2324 0.3013 5.87e-43
9 1i7q:A 517 369 0.2595 0.2108 0.2954 1.30e-35 1i7q:C, 1i7s:A, 1i7s:C
10 6za4:B 423 218 0.1500 0.1489 0.2890 7.20e-10 3rv6:B, 3rv9:C
11 3hwo:A 379 150 0.1000 0.1108 0.2800 4.77e-08 3hwo:B, 5jxz:A, 5jxz:B, 5jy4:A, 5jy4:B, 5jy8:A, 5jy8:B, 5jzd:A, 5jzd:B
12 5jy9:B 424 266 0.1452 0.1439 0.2293 5.46e-08 2fn0:A, 2fn0:B, 2fn1:A, 2fn1:B, 5jy9:A
13 3veh:B 451 112 0.0857 0.0798 0.3214 8.64e-07 2g5f:A, 2g5f:B, 3log:B, 8qc4:A, 8qc4:B, 8qn5:A, 8qn5:B, 8qn5:C, 8qn5:D, 3rv6:A, 3rv7:A, 3rv7:B, 3rv7:C, 3rv7:D, 3rv8:A, 3rv8:B, 3rv8:C, 3rv8:D, 3rv9:A, 3rv9:B, 3rv9:D, 3st6:A, 3st6:B, 3veh:A, 3veh:C, 3veh:D, 6za4:A, 6za4:C, 6za4:D, 6za5:B, 6za5:D
14 3bzn:A 430 82 0.0619 0.0605 0.3171 1.13e-04
15 8w6v:A 494 115 0.0786 0.0668 0.2870 0.001 8w6v:B, 8w71:A, 8w71:B
16 8e7s:W 133 55 0.0381 0.1203 0.2909 2.5 8e7s:w, 8ec0:W
17 3r75:B 622 94 0.0690 0.0466 0.3085 2.5 3r75:A, 3r76:A, 3r76:B
18 1nwx:T 223 68 0.0500 0.0942 0.3088 2.8 7a0r:S, 7a0s:S, 7a18:S, 3cf5:S, 3dll:S, 5dm6:S, 5dm7:S, 4io9:S, 4ioa:S, 4ioc:S, 5jvg:S, 5jvh:S, 1nwy:T, 3pio:S, 3pip:S, 1sm1:T, 4u67:S, 4v4g:BW, 4v4g:DW, 4v4g:FW, 4v4g:HW, 4v4g:JW, 4v4p:AV, 4v4r:BZ, 4v4s:BZ, 4v4t:BZ, 4wfn:S, 1xbp:T, 2zjp:S, 2zjq:S, 2zjr:S
19 6iy9:A 325 52 0.0405 0.0523 0.3269 4.6 6iy9:B
20 2pc6:A 164 45 0.0381 0.0976 0.3556 9.3 2pc6:B, 2pc6:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218