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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKQDGEEGTEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVCVDQRLITNKKCPICRVDIEAQLPSES

The query sequence (length=69) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2kiz:A 69 69 0.9855 0.9855 0.9855 6.74e-45 5lg0:A, 5lg7:A, 7p2k:A
2 7r70:A 150 54 0.6522 0.3000 0.8333 1.03e-28 5d0i:A, 5d0i:B, 5d0k:C, 5d0k:F, 5d0k:I, 5d0k:L, 7r70:B, 7r71:A
3 5d0m:C 60 49 0.5652 0.6500 0.7959 3.82e-22 5ulh:C, 5ulk:C
4 6w7z:B 71 54 0.3188 0.3099 0.4074 3.00e-11 6w9a:B, 6w9a:D, 6w9d:B, 6w9d:E, 6w9d:H
5 2ect:A 78 64 0.3623 0.3205 0.3906 2.16e-10
6 1iym:A 55 51 0.3333 0.4182 0.4510 4.68e-10
7 1x4j:A 75 44 0.3043 0.2800 0.4773 5.57e-10
8 4v3k:C 75 44 0.3043 0.2800 0.4773 9.10e-10 7ojx:A, 4v3k:F, 4v3l:C
9 7bvw:A 79 62 0.3333 0.2911 0.3710 5.16e-09 7bvw:B
10 5zbu:A 74 54 0.3478 0.3243 0.4444 1.88e-08 5zbu:D, 5zc4:A, 5zc4:D
11 5ywr:B 87 39 0.2319 0.1839 0.4103 3.48e-07
12 2lxh:C 58 50 0.2464 0.2931 0.3400 2.00e-06 2lxp:C
13 2l0b:A 91 49 0.2754 0.2088 0.3878 2.78e-06
14 1chc:A 68 51 0.2609 0.2647 0.3529 3.10e-06
15 4lad:B 69 45 0.2464 0.2464 0.3778 7.56e-06
16 2ecn:A 70 50 0.2754 0.2714 0.3800 2.19e-05 5xek:A
17 6a3z:A 56 45 0.2464 0.3036 0.3778 2.32e-05
18 2ep4:A 74 71 0.3188 0.2973 0.3099 5.17e-05
19 8aaf:e 1527 55 0.3043 0.0138 0.3818 1.72e-04 8agt:e, 8agu:e, 8agv:e, 8agw:e, 8agx:e, 8agz:e
20 7t92:C 317 51 0.2464 0.0536 0.3333 2.92e-04
21 2ecm:A 55 48 0.2319 0.2909 0.3333 6.71e-04
22 6f98:A 78 31 0.1739 0.1538 0.3871 0.001
23 2d8t:A 71 59 0.2609 0.2535 0.3051 0.001
24 5dka:A 96 57 0.3188 0.2292 0.3860 0.002 5dka:B, 8gbq:B, 8gcb:B
25 7ynx:A 188 56 0.2609 0.0957 0.3214 0.004 2jrj:A, 7ynx:B
26 5d1l:B 111 62 0.2609 0.1622 0.2903 0.004 5d1k:B, 5d1m:B
27 4orh:H 142 56 0.2609 0.1268 0.3214 0.008 4ayc:A, 4ayc:B, 4orh:C, 4orh:G, 4orh:K, 4orh:L, 4whv:C, 4whv:D, 4whv:I, 4whv:J
28 6wi7:A 206 58 0.2464 0.0825 0.2931 0.010 2ckl:A, 8grm:M, 2h0d:A, 7nd1:H, 8pp7:K, 8pp7:M, 4r8p:K, 4r8p:M, 3rpg:B, 6wi8:A, 6wi8:B
29 6wi7:A 206 47 0.2464 0.0825 0.3617 0.82 2ckl:A, 8grm:M, 2h0d:A, 7nd1:H, 8pp7:K, 8pp7:M, 4r8p:K, 4r8p:M, 3rpg:B, 6wi8:A, 6wi8:B
30 4r8p:L 254 47 0.2464 0.0669 0.3617 0.029 2ckl:B, 8grm:N, 2h0d:B, 7nd1:A, 8pp7:L, 8pp7:N, 4r8p:N, 3rpg:C, 4s3o:B, 4s3o:E
31 4qpl:A 153 29 0.1739 0.0784 0.4138 0.054 4qpl:C, 3v3l:A, 3v3l:B
32 7zj3:A 86 45 0.2174 0.1744 0.3333 0.11 8a38:A, 8a38:B, 8a38:C, 8ams:C, 8ams:D, 7zj3:D, 7zj3:G, 7zj3:J
33 7oni:R 86 30 0.1594 0.1279 0.3667 0.13 2ecl:A, 6v9i:R
34 2ma6:A 61 28 0.1594 0.1803 0.3929 0.15
35 5o6c:A 252 64 0.2464 0.0675 0.2656 0.17 6t7f:A
36 2djb:A 72 50 0.1739 0.1667 0.2400 0.19
37 2ea6:A 69 50 0.2174 0.2174 0.3000 0.70
38 3k1l:A 376 82 0.2754 0.0505 0.2317 0.75 3k1l:B
39 2lgv:A 100 44 0.1884 0.1300 0.2955 1.0 4a0c:D, 8b3g:R, 8b3i:R, 7b5l:R, 7b5m:R, 7b5n:R, 7b5s:R, 8cdk:R, 3dpl:R, 3dqv:R, 3dqv:Y, 4f52:B, 4f52:D, 8gq6:E, 8gq6:D, 8h33:D, 8h33:K, 8h33:L, 8h33:E, 8h34:R, 8h34:Q, 8h34:E, 8h34:D, 8h34:L, 8h34:K, 8h35:E, 8h35:D, 8h35:L, 8h35:K, 8h35:R, 8h35:Q, 8h35:W, 8h35:X, 8h36:E, 8h36:D, 8h37:E, 8h37:D, 8h37:R, 8h37:Q, 8h38:R, 8h3a:R, 8h3f:R, 8h3q:E, 8h3r:E, 8h3r:D, 2hye:D, 8jaq:R, 8jaq:V, 8jas:R, 8jas:V, 8jav:R, 8jav:V, 1ldj:B, 1ldk:C, 5n4w:R, 8or0:B, 8or2:B, 8or3:B, 4p5o:B, 4p5o:D, 7plo:T, 8pql:K, 8q7h:C, 8q7h:D, 8q7r:R, 8qu8:E, 8r5h:R, 6r7i:R, 6r7n:R, 8rhz:C, 8rhz:D, 3rtr:B, 3rtr:D, 3rtr:F, 3rtr:H, 8rwz:R, 8rx0:R, 6ttu:R, 1u6g:B, 8wqa:J, 8wqa:I, 8wqb:I, 8wqb:E, 8wqc:F, 8wqc:J, 8wqe:J, 8wqe:I, 8wqf:I, 8wqf:E, 8wqg:F, 8wqg:J, 8wqh:J, 8wqh:B, 7z8b:R, 7z8r:R, 7z8t:R, 7z8v:R, 7zbz:R
40 7yui:B 232 38 0.2029 0.0603 0.3684 1.3 3b08:K, 3b08:B, 3b08:E, 3b08:H, 3b0a:B
41 9j8e:B 296 34 0.1884 0.0439 0.3824 1.4 9j8e:A
42 5tr9:A 246 33 0.1884 0.0528 0.3939 1.6 5tr9:B, 5ufa:A, 5ufa:B, 5ufa:C
43 5ait:A 129 52 0.2174 0.1163 0.2885 1.7 5aiu:A, 4ap4:A, 3ng2:A, 3ng2:B, 4ppe:A, 4ppe:B, 2xeu:A
44 5ait:A 129 52 0.2174 0.1163 0.2885 1.7 5aiu:A, 4ap4:A, 3ng2:A, 3ng2:B, 4ppe:A, 4ppe:B, 2xeu:A
45 5jw7:B 61 43 0.2319 0.2623 0.3721 1.7
46 7v6c:A 1540 28 0.1884 0.0084 0.4643 1.8
47 8hf0:A 1561 28 0.1884 0.0083 0.4643 2.1 8hf0:D, 8hf1:A, 8hf1:D, 8hf1:G, 7w0a:A, 7w0a:E, 7w0c:A, 7w0d:A, 7w0e:A, 7w0f:A
48 7w0b:A 1586 28 0.1884 0.0082 0.4643 2.1 7w0d:F
49 8eaz:A 254 38 0.2029 0.0551 0.3684 2.3 8bvl:A, 8bvl:B, 8eaz:B, 7yuj:A, 7yuj:B
50 5j3x:B 389 56 0.2609 0.0463 0.3214 3.6 4a4b:A, 4a4c:A, 1b47:A, 1b47:B, 1b47:C, 3bum:B, 3bun:B, 3buo:B, 3buo:D, 3buw:B, 3buw:D, 3bux:B, 3bux:D, 2cbl:A, 1fbv:A, 4gpl:B, 5hkx:A, 5hky:A, 5hkz:A, 5hl0:A, 5j3x:A, 5j3x:C, 5j3x:D, 5j3x:E, 5j3x:F, 2k4d:A, 5o76:A, 5o76:C, 3ob1:B, 3ob2:B, 3plf:B, 3plf:D, 7siy:A, 6xar:A, 6xar:B, 2y1m:A, 2y1m:B, 2y1m:C, 2y1m:D, 2y1m:E, 2y1m:F, 2y1n:A, 2y1n:C, 1yvh:A
51 3zni:A 390 55 0.2609 0.0462 0.3273 3.6 4a49:A, 5axi:B, 5axi:A, 5axi:C, 9fqh:A, 9fqi:A, 9fqj:A, 9fqj:B, 8gcy:A, 2ldr:A, 3pfv:A, 3pfv:B, 8qng:A, 8qnh:A, 8qni:A, 8qtg:A, 8qth:A, 8qtj:A, 8qtk:A, 8vw4:A, 8vw4:B, 8vw5:A, 8vw5:B, 3zni:E, 3zni:I, 3zni:M
52 8dos:A 247 22 0.1594 0.0445 0.5000 4.1 8dos:B
53 5h7r:D 124 47 0.2174 0.1210 0.3191 4.9 5h7s:D, 5h7s:B
54 8sew:A 629 18 0.1304 0.0143 0.5000 4.9 8seu:A, 8seu:B, 8seu:C, 8seu:D, 8sev:A, 8sev:B, 8sev:C, 8sev:D, 8sew:B, 8sew:C, 8sew:D, 8sex:A, 8sex:B, 8sex:C, 8sex:D, 8sey:A, 8sey:B, 8sey:C, 8sey:D, 8sez:A, 8sez:B, 8sez:C, 8sez:D, 8sf0:A, 8sf0:B, 8sf0:C, 8sf0:D
55 7z36:B 446 44 0.1884 0.0291 0.2955 5.0 6h3a:A, 6h3a:F, 6qaj:A, 6qaj:B, 6qu1:A, 2yvr:A, 2yvr:B, 7z36:A
56 5f6d:A 156 14 0.1449 0.0641 0.7143 5.6 5f6u:A, 5f6v:A, 5f6w:A, 5f6x:A, 5f6y:A, 6syf:A, 6syf:B, 6syf:C, 6syf:D
57 9atn:A 98 38 0.1739 0.1224 0.3158 5.8
58 8eeg:B 440 28 0.1594 0.0250 0.3929 6.7 8eef:A, 8eef:B, 8eeg:A, 8eeh:A, 8eeh:B, 8eei:A, 8eei:B, 8eej:B, 8eej:A, 8eek:A, 8eek:B, 8eel:A, 8eel:B, 8eem:A, 8eem:B, 8een:B, 8een:A, 8eeo:A, 8eeo:B
59 4a0c:F 80 22 0.1304 0.1125 0.4091 6.9 8ij1:R, 7shk:R
60 5jne:B 157 14 0.1449 0.0637 0.7143 7.0 5jne:F
61 6jgz:B 3485 18 0.1304 0.0026 0.5000 7.0 6jg3:A, 6jg3:B, 6jg3:C, 6jg3:D, 6jgz:D, 6jgz:F, 6jgz:H, 6jh6:B, 6jh6:D, 6jh6:F, 6jh6:H, 6jhn:A, 6jhn:C, 6jhn:E, 6jhn:G, 6ji0:A, 6ji0:C, 6ji0:E, 6ji0:G, 6jrr:A, 6jrr:C, 6jrr:E, 6jrr:G
62 4s3o:C 95 48 0.2029 0.1474 0.2917 7.1 4s3o:F
63 5go9:A 3423 18 0.1304 0.0026 0.5000 7.1 5go9:B, 5go9:C, 5go9:D, 5goa:A, 5goa:B, 5goa:C, 5goa:D
64 6jiy:A 3521 18 0.1304 0.0026 0.5000 7.4 6ji8:A, 6ji8:D, 6ji8:G, 6ji8:J, 6jii:B, 6jii:E, 6jii:H, 6jii:K, 6jiu:A, 6jiu:D, 6jiu:G, 6jiu:J, 6jiy:D, 6jiy:G, 6jiy:J, 6jv2:A, 6jv2:C, 6jv2:E, 6jv2:G
65 6jrs:A 3488 18 0.1304 0.0026 0.5000 7.6 6jrs:D, 6jrs:G, 6jrs:J
66 6wou:A 3921 18 0.1304 0.0023 0.5000 7.6 6wou:B, 6wou:C, 6wou:D, 6wov:A, 6wov:B, 6wov:C, 6wov:D
67 8dvv:A 3886 18 0.1304 0.0023 0.5000 7.7 8dvv:B, 8dvv:C, 8dvv:D
68 8uxh:A 4004 18 0.1304 0.0022 0.5000 7.7 8uxh:B, 8uxh:C, 8uxh:D, 8uxi:A, 8uxi:B, 8uxi:C, 8uxi:D
69 8dty:A 4004 18 0.1304 0.0022 0.5000 7.7 8dty:B, 8dty:C, 8dty:D
70 7vml:A 4044 18 0.1304 0.0022 0.5000 7.7 7aih:UA, 7am2:UA, 7ane:UA, 5dat:l1, 5gak:r, 6hd7:r, 6j3z:19, 6j40:19, 6j40:39, 5mc6:AZ, 6n8k:s, 6n8l:s, 6n8m:S, 6n8n:S, 6n8o:S, 7nrc:Lt, 6o1o:F, 6o1o:G, 6o1o:H, 6qik:p, 6qtz:p, 6ri5:p, 7rr5:L1, 6rzz:p, 6s05:p, 5t62:S, 5t6r:S, 6tnu:BT, 7vml:B, 7vml:C, 7vml:D, 7vmm:A, 7vmm:B, 7vmm:C, 7vmm:D, 7vmn:A, 7vmn:B, 7vmn:C, 7vmn:D, 7vmo:A, 7vmo:B, 7vmo:C, 7vmo:D, 7vmp:A, 7vmp:B, 7vmp:C, 7vmp:D, 7vmq:A, 7vmq:B, 7vmq:C, 7vmq:D, 7vmr:A, 7vmr:B, 7vmr:C, 7vmr:D, 7vms:A, 7vms:B, 7vms:C, 7vms:D
71 8dtz:A 4061 18 0.1304 0.0022 0.5000 7.7 8dtz:B, 8dtz:C, 8dtz:D
72 8uxl:A 4232 18 0.1304 0.0021 0.5000 8.0 7u9q:A, 7u9q:D, 7u9q:B, 7u9q:C, 7u9r:A, 7u9r:D, 7u9r:B, 7u9r:C, 7u9t:A, 7u9t:D, 7u9t:B, 7u9t:C, 7u9x:A, 7u9x:B, 7u9x:C, 7u9x:D, 7u9z:A, 7u9z:B, 7u9z:C, 7u9z:D, 7ua1:A, 7ua1:B, 7ua1:C, 7ua1:D, 7ua5:A, 7ua5:B, 7ua5:C, 7ua5:D, 7ua9:A, 7ua9:B, 7ua9:C, 7ua9:D, 8uq2:A, 8uq2:B, 8uq2:C, 8uq2:D, 8uq3:A, 8uq3:B, 8uq3:C, 8uq3:D, 8uq4:A, 8uq4:B, 8uq4:C, 8uq4:D, 8uq5:A, 8uq5:B, 8uq5:C, 8uq5:D, 8uxc:A, 8uxc:B, 8uxc:C, 8uxc:D, 8uxe:A, 8uxe:B, 8uxe:C, 8uxe:D, 8uxf:A, 8uxf:B, 8uxf:C, 8uxf:D, 8uxg:A, 8uxg:B, 8uxg:C, 8uxg:D, 8uxl:B, 8uxl:C, 8uxl:D, 8uxm:A, 8uxm:B, 8uxm:C, 8uxm:D
73 7ua3:A 4443 18 0.1304 0.0020 0.5000 8.1 7ua3:B, 7ua3:C, 7ua3:D, 7ua4:A, 7ua4:B, 7ua4:C, 7ua4:D
74 6nw5:A 331 32 0.1739 0.0363 0.3750 8.3 6nw5:B, 6nw5:C, 6nw5:D
75 5gky:A 3660 18 0.1304 0.0025 0.5000 8.4 5gky:C, 5gky:E, 5gky:G, 5gkz:A, 5gkz:C, 5gkz:E, 5gkz:G, 5gl0:A, 5gl0:C, 5gl0:E, 5gl0:G, 5gl1:A, 5gl1:C, 5gl1:E, 5gl1:G
76 3j8h:A 3660 18 0.1304 0.0025 0.5000 8.5 3j8h:C, 3j8h:E, 3j8h:G
77 7umz:A 3927 18 0.1304 0.0023 0.5000 8.7 6g4s:s, 6g4w:s, 5j4z:G, 5j7y:G, 5j8k:G, 5tzs:Q, 7umz:D, 7umz:B, 7umz:C, 5wyj:UC, 5wyj:AG, 5wyk:AG, 5wyk:UC, 4wz7:A, 6xyw:AP
78 7tzc:A 4404 18 0.1304 0.0020 0.5000 8.7 3rqr:A, 8sen:A, 8sen:B, 8sen:C, 8sen:D, 8seo:A, 8seo:B, 8seo:C, 8seo:D, 8sep:A, 8sep:B, 8sep:C, 8sep:D, 8seq:A, 8seq:B, 8seq:C, 8seq:D, 8ser:A, 8ser:B, 8ser:C, 8ser:D, 8ses:A, 8ses:B, 8ses:C, 8ses:D, 8set:A, 8set:B, 8set:C, 8set:D, 7tzc:B, 7tzc:G, 7tzc:I
79 8duj:A 3823 18 0.1304 0.0024 0.5000 8.8
80 8duj:J 3892 18 0.1304 0.0023 0.5000 8.8
81 6wot:A 4197 18 0.1304 0.0021 0.5000 8.8 6wot:B, 6wot:C, 6wot:D
82 7m6a:A 4306 18 0.1304 0.0021 0.5000 8.8 7m6a:G, 7m6a:B, 7m6a:I, 7m6l:A, 7m6l:G, 7m6l:B, 7m6l:I
83 7dvq:M 191 55 0.2319 0.0838 0.2909 8.8 8i0r:K, 8i0s:K, 8i0t:K, 5z56:M, 5z58:M
84 4v4c:B 274 29 0.1449 0.0365 0.3448 8.9 4v4c:D, 4v4c:F, 4v4c:H, 4v4c:J, 4v4c:L, 4v4c:N, 4v4c:P, 4v4c:R, 4v4c:T, 4v4c:V, 4v4c:X, 4v4d:B, 4v4d:D, 4v4d:F, 4v4d:H, 4v4d:J, 4v4d:L, 4v4d:N, 4v4d:P, 4v4d:R, 4v4d:T, 4v4d:V, 4v4d:X, 4v4e:B, 4v4e:D, 4v4e:F, 4v4e:H, 4v4e:J, 4v4e:L, 4v4e:N, 4v4e:P, 4v4e:R, 4v4e:T, 4v4e:V, 4v4e:X
85 7cf9:A 3949 18 0.1304 0.0023 0.5000 9.0 7cf9:C, 7cf9:E, 7cf9:G, 8dtb:G, 8dtb:D, 6m2w:A, 6m2w:D, 6m2w:G, 6m2w:J
86 7t65:A 4252 18 0.1304 0.0021 0.5000 9.0 7t64:A, 7t64:B, 7t64:C, 7t64:D, 7t65:B, 7t65:C, 7t65:D
87 5din:B 124 61 0.2754 0.1532 0.3115 9.1 5din:A
88 8duj:D 3865 18 0.1304 0.0023 0.5000 9.2
89 8duj:G 3933 18 0.1304 0.0023 0.5000 9.2
90 8dve:G 3944 18 0.1304 0.0023 0.5000 9.2 8dtb:A, 8dve:D, 8dve:A, 8dve:J
91 6foo:A 4168 18 0.1304 0.0022 0.5000 9.2 5dat:m2, 5dc3:m2, 5dgv:m2, 5fci:m2, 5fcj:m2, 6foo:B, 6foo:C, 6foo:D, 5i4l:m2, 5it7:KK, 6j3z:20, 6j3z:21, 5j4z:B, 6j40:20, 6j40:40, 6j40:21, 6j40:41, 8j5k:4, 8j5k:9, 5j7y:B, 5j8k:B, 7lh5:BK, 7lh5:DK, 5luf:B, 5lyb:m2, 5mrc:dd, 5mre:dd, 5mrf:dd, 5obm:m2, 5on6:m2, 5ot7:m, 7pkq:V, 7pkt:Y, 6q95:I, 5tga:m2, 5tzs:Z, 5tzs:m, 4u3m:m2, 4u3n:m2, 4u3u:m2, 4u4n:m2, 4u4o:m2, 4u4q:m2, 4u4r:m2, 4u4u:m2, 4u4y:m2, 4u4z:m2, 4u50:m2, 4u51:m2, 4u52:m2, 4u53:m2, 4u55:m2, 4u56:m2, 4u6f:m2, 4uq8:B, 6uz7:AK, 4v3p:SG, 4v5g:BK, 4v5g:DK, 4v5l:BK, 4v5p:BK, 4v5p:DK, 4v5q:BK, 4v5q:DK, 4v5r:BK, 4v5r:DK, 4v5s:BK, 4v5s:DK, 4v6i:AG, 4v88:DK, 4v8o:BK, 4v8q:AK, 4v8t:K, 4v8y:BK, 4v8z:BK, 4v90:BK, 8w4p:4, 6woo:K, 7y1a:A, 7y5e:A8, 7y5e:AC, 7y7a:AN, 7y7a:AY, 5z3g:d

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218