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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKILVIQGPNLNMLGHRGMVTLDQIHEIMQTFVKQGNLDVELEFFQTNFEGEIIDKIQESVGSDYEGIIINPGAFSHTSI
AIADAIMLAGKPVIEVHLTNIQAREEFRKNSYTGAACGGVIMGFGPLGYNMALMAMVNILAEMKAFQEAQKNN

The query sequence (length=153) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2c4w:A 168 158 0.9935 0.9048 0.9620 9.05e-108 4b6r:A, 4b6r:C, 4b6r:B, 4b6s:A, 4b6s:C, 4b6s:B, 2c57:A, 2c57:B, 2c57:C, 2c57:D, 2c57:E, 2c57:F, 2c57:G, 2c57:H, 2c57:I, 2c57:J, 2c57:K, 2c57:L, 1j2y:A, 2wks:A, 2wks:B, 2wks:C, 2wks:F, 2wks:D, 2wks:E, 2xb9:A, 2xb9:B, 2xd9:A, 2xd9:B, 2xd9:C, 2xda:A
2 5b6p:B 145 136 0.4052 0.4276 0.4559 9.77e-35 5b6p:C, 5b6p:G, 5ydb:A, 5ydb:B, 5ydb:C, 5ydb:D
3 6hs9:A 145 139 0.4183 0.4414 0.4604 1.26e-31 6hsa:A
4 8idr:C 147 151 0.4052 0.4218 0.4106 1.62e-31 8idr:A, 8idr:B, 8idr:D, 8idu:A, 8idu:B, 8idu:C, 8idu:D, 8idu:E, 8idu:F
5 1v1j:A 150 135 0.3660 0.3733 0.4148 3.21e-27 2bt4:A, 2bt4:B, 2bt4:C, 2bt4:D, 2bt4:E, 2bt4:F, 2bt4:G, 2bt4:H, 2bt4:I, 2bt4:J, 2bt4:K, 2bt4:L, 2cjf:A, 2cjf:B, 2cjf:C, 2cjf:D, 2cjf:E, 2cjf:F, 2cjf:G, 2cjf:H, 2cjf:I, 2cjf:J, 2cjf:K, 2cjf:L, 1gtz:A, 1gtz:B, 1gtz:C, 1gtz:D, 1gtz:E, 1gtz:F, 1gtz:G, 1gtz:H, 1gtz:I, 1gtz:J, 1gtz:K, 1gtz:L, 1gu1:A, 1gu1:B, 1gu1:C, 1gu1:D, 1gu1:E, 1gu1:F, 1gu1:G, 1gu1:H, 1gu1:I, 1gu1:J, 1gu1:K, 1gu1:L, 1v1j:B, 1v1j:C, 1v1j:D, 1v1j:E, 1v1j:F, 1v1j:G, 1v1j:H, 1v1j:I, 1v1j:J, 1v1j:K, 1v1j:L
6 3n8k:M 151 134 0.3268 0.3311 0.3731 7.30e-24 4b6o:A, 4b6p:A, 4b6q:A, 4civ:A, 4ciw:A, 4cix:A, 4ciy:A, 4cky:A, 4cl0:A, 1h0r:A, 1h0s:A, 4ki7:A, 4ki7:B, 4ki7:C, 4ki7:D, 4ki7:E, 4ki7:F, 4ki7:G, 4ki7:H, 4ki7:I, 4ki7:J, 4ki7:K, 4ki7:L, 4ki7:N, 4ki7:Q, 4ki7:O, 4ki7:P, 4ki7:R, 4ki7:S, 4ki7:T, 4ki7:U, 4ki7:V, 4ki7:W, 4ki7:X, 4kij:A, 4kiu:A, 4kiu:B, 4kiu:E, 4kiu:C, 4kiu:D, 4kiu:F, 4kiu:G, 4kiu:H, 4kiu:I, 4kiu:J, 4kiu:K, 4kiu:L, 4kiu:N, 4kiu:O, 4kiu:P, 4kiu:Q, 4kiu:R, 4kiu:T, 4kiu:U, 4kiu:V, 4kiu:W, 4kiu:X, 4kiw:A, 4kiw:B, 4kiw:C, 4kiw:D, 4kiw:E, 4kiw:G, 4kiw:H, 4kiw:J, 4kiw:K, 4kiw:L, 4kiw:M, 4kiw:N, 4kiw:O, 4kiw:P, 4kiw:Q, 4kiw:R, 4kiw:S, 4kiw:T, 4kiw:U, 4kiw:V, 4kiw:W, 4kiw:X, 3n59:C, 3n59:G, 3n76:A, 3n7a:A, 3n7a:B, 3n7a:C, 3n7a:D, 3n7a:E, 3n7a:F, 3n7a:G, 3n7a:H, 3n7a:I, 3n7a:J, 3n7a:K, 3n7a:L, 3n7a:M, 3n7a:N, 3n7a:O, 3n7a:P, 3n7a:Q, 3n7a:R, 3n7a:S, 3n7a:T, 3n7a:U, 3n7a:V, 3n7a:W, 3n7a:X, 3n86:A, 3n86:L, 3n86:B, 3n86:E, 3n86:C, 3n86:D, 3n86:G, 3n86:F, 3n86:H, 3n86:J, 3n86:I, 3n86:K, 3n86:M, 3n86:X, 3n86:N, 3n86:Q, 3n86:O, 3n86:P, 3n86:S, 3n86:R, 3n86:T, 3n86:V, 3n86:U, 3n86:W, 3n87:A, 3n87:L, 3n87:B, 3n87:E, 3n87:C, 3n87:D, 3n87:G, 3n87:F, 3n87:H, 3n87:I, 3n87:J, 3n87:K, 3n87:M, 3n87:N, 3n87:O, 3n87:P, 3n87:Q, 3n87:R, 3n87:S, 3n87:T, 3n87:V, 3n87:U, 3n87:W, 3n87:X, 3n8k:A, 3n8k:B, 3n8k:C, 3n8k:D, 3n8k:E, 3n8k:F, 3n8k:G, 3n8k:H, 3n8k:I, 3n8k:J, 3n8k:K, 3n8k:L, 3n8k:N, 3n8k:O, 3n8k:P, 3n8k:R, 3n8k:S, 3n8k:T, 3n8k:U, 3n8k:V, 3n8k:W, 3n8n:A, 3n8n:B, 3n8n:C, 3n8n:D, 3n8n:E, 3n8n:F, 3n8n:G, 3n8n:I, 3n8n:J, 3n8n:K, 3n8n:L, 3n8n:T, 3n8n:U, 3n8n:V, 4v0s:A, 4v0s:B, 2xb8:A, 2y71:A, 2y76:A, 2y77:A
7 8ghf:A 910 80 0.1438 0.0242 0.2750 0.17 8ghf:B, 8ghf:C, 8ghf:D, 3mt5:A, 8s3e:A, 8s3e:B, 8s3e:C, 8s3e:D, 3u6n:A, 3u6n:B, 3u6n:C, 3u6n:D, 3u6n:E, 3u6n:F, 3u6n:G, 3u6n:H, 6v22:A, 6v22:B, 6v22:C, 6v22:D, 6v38:A, 6v38:B, 6v38:C, 6v38:D, 6v5a:A, 7ynz:A, 7ynz:C, 7ynz:E, 7ynz:G, 7yo0:A, 7yo0:C, 7yo0:E, 7yo0:G, 7yo1:A, 7yo1:C, 7yo1:E, 7yo1:G, 7yo3:A, 7yo5:A, 7yo5:B, 7yo5:C, 7yo5:D
8 6v35:A 914 80 0.1438 0.0241 0.2750 0.17 6v35:D, 6v35:B, 6v35:C, 8z3s:A, 8z3s:B, 8z3s:C, 8z3s:D
9 4b5n:A 354 102 0.1634 0.0706 0.2451 1.4 5k0r:A, 5k1k:A, 5k1m:A, 5k1q:A, 5k1u:A, 5k1w:A
10 8fr7:A 1275 49 0.1046 0.0125 0.3265 4.5 8fr7:C, 8fr7:B
11 6yxy:BE 407 81 0.1242 0.0467 0.2346 5.2 7aoi:BE, 6hiv:BE, 6hix:BE, 6yxx:BE
12 1f5s:A 210 74 0.1503 0.1095 0.3108 6.0 1f5s:B, 1j97:A, 1j97:B, 1l7m:A, 1l7m:B, 1l7n:A, 1l7n:B, 1l7o:A, 1l7o:B, 1l7p:A, 1l7p:B
13 4xqk:A 1517 24 0.0850 0.0086 0.5417 6.5 4xqk:B
14 3cf4:A 766 59 0.0915 0.0183 0.2373 7.0
15 2yll:A 436 34 0.0850 0.0298 0.3824 7.6 4az5:A, 4az6:A, 4az7:A, 4azb:A, 2yl6:A, 2yl8:A
16 4nqa:H 319 17 0.0654 0.0313 0.5882 7.8 6a5y:D, 6a5z:D, 6a5z:L, 6a60:D, 7a77:A, 7a78:A, 7a79:A, 7a79:B, 3a9e:A, 2acl:A, 2acl:C, 2acl:E, 2acl:G, 7aos:A, 7b88:A, 7b9o:A, 7bk4:A, 7bk4:C, 1by4:A, 1by4:B, 1by4:C, 1by4:D, 7cfo:A, 7cfo:B, 7cfo:D, 7cfo:C, 4cn2:C, 4cn2:D, 4cn3:A, 4cn3:D, 4cn3:B, 4cn3:C, 4cn5:A, 4cn5:B, 4cn7:A, 4cn7:B, 4cn7:E, 4cn7:F, 1dsz:B, 3dzy:A, 3e94:A, 5ec9:A, 3fal:A, 3fal:C, 1fby:A, 1fby:B, 6fbq:A, 6fbq:B, 6fbr:A, 6fbr:B, 3fc6:A, 3fc6:C, 1fm6:A, 1fm6:U, 1fm9:A, 3fug:A, 1g5y:B, 1g5y:C, 3h0a:A, 1h9u:A, 1h9u:B, 1h9u:C, 1h9u:D, 8hbm:A, 8hbm:E, 6hn6:A, 8j54:C, 8j54:D, 8j54:E, 8j54:F, 5ji0:A, 6jno:A, 6jno:D, 6jnr:A, 6jnr:B, 4k4j:A, 4k6i:A, 1k74:A, 3kwy:A, 6l6k:A, 6lb4:A, 6lb5:A, 6lb5:C, 6lb6:A, 5lyq:A, 4m8e:A, 4m8h:A, 5mj5:A, 5mk4:A, 5mk4:C, 5mkj:A, 5mku:A, 5mmw:A, 1mv9:A, 1mvc:A, 1mzn:A, 1mzn:C, 1mzn:E, 1mzn:G, 4n5g:A, 4n5g:D, 4n8r:A, 4n8r:D, 7nke:A, 7nke:C, 2nll:A, 4nqa:A, 3nsq:B, 3oap:A, 4oc7:A, 3ozj:A, 3ozj:C, 2p1t:A, 2p1u:A, 2p1v:A, 3pcu:A, 7pdq:A, 7pdt:A, 7pdt:B, 4poh:A, 4poj:A, 4pp3:A, 4pp5:A, 8pp0:A, 1r0n:A, 3r29:A, 3r29:B, 3r2a:B, 3r2a:D, 3r2a:A, 3r2a:C, 3r5m:A, 3r5m:C, 1rdt:A, 4rfw:A, 4rmc:A, 4rmd:A, 4rme:A, 1rxr:A, 6sjm:A, 6sti:A, 5tbp:A, 5tbp:C, 5tbp:B, 5tbp:D, 1uhl:A, 3uvv:B, 7uw2:A, 7uw4:A, 1xdk:A, 1xdk:E, 1xls:A, 1xls:B, 1xls:C, 1xls:D, 1xv9:A, 1xv9:C, 1xvp:A, 1xvp:C, 6xwg:C, 6xwh:C, 6xwh:D, 1ynw:B, 5z12:C, 5z12:B, 5zqu:A, 5zqu:C, 5zqu:B, 5zqu:D, 4zsh:A, 2zxz:A, 2zy0:A, 2zy0:C
17 3dzu:A 289 17 0.0654 0.0346 0.5882 8.0 3e00:A, 5uan:A
18 5m5w:B 1183 53 0.0719 0.0093 0.2075 9.2 4c2m:B, 4c2m:Q, 4c3h:B, 4c3i:B, 4c3j:B, 5g5l:B, 6h67:B, 6h68:B, 6hko:B, 6hlq:B, 6hlr:B, 5m3f:B, 5m3m:B, 5m5x:B, 5m5y:B, 5m64:B, 5n5y:B, 5n5z:B, 5n60:B, 5n61:B, 5oa1:B, 6rqh:B, 6rql:B, 6rqt:B, 6rrd:B, 6rui:B, 6ruo:B, 6rwe:B, 6tps:B, 5w5y:B, 5w64:B, 5w65:B, 5w66:B, 4ym7:AB, 4ym7:BB, 4ym7:CB, 4ym7:DB, 4ym7:EB, 4ym7:FB
19 5lmx:B 1115 53 0.0719 0.0099 0.2075 9.3

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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