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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MIVFTDLDGTLLDERGELGPAREALERLRALGVPVVPVTAKTRKEVEALGLEPPFIVENGGGLYLPRDWPVRAGRPKGGY
RVVSLAWPYRKVRARLREAEALAGRPILGYGDLTAEAVARLTGLSREAARRAKAREYDETLVLCPEEVEAVLEALEAVGL
EWTHGGRFYHAAKGADKGRAVARLRALWPDPEEARFAVGLGDSLNDLPLFRAVDLAVYVGRGDPPEGVLATPAPGPEGFR
YAVERYLLPRLS

The query sequence (length=252) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3zx4:B 254 252 1.0000 0.9921 1.0000 2.24e-175 3zu6:B, 3zup:A, 3zup:B, 3zw7:A, 3zw7:B, 3zwd:A, 3zwd:B, 3zwk:A, 3zwk:B, 3zx4:A, 3zx5:A, 3zx5:B
2 1wzc:B 244 225 0.2897 0.2992 0.3244 2.51e-27 1wzc:A
3 1kyt:A 225 78 0.0913 0.1022 0.2949 0.005 1kyt:B, 1l6r:A, 1l6r:B
4 3pgv:A 259 64 0.0952 0.0927 0.3750 0.048 3pgv:B, 3pgv:C, 3pgv:D
5 2ho4:B 252 42 0.0794 0.0794 0.4762 0.15 2ho4:A
6 4zev:A 290 49 0.0714 0.0621 0.3673 0.17 4qjb:A, 4qjb:B, 4zev:B, 4zew:A, 4zew:B, 4zex:A, 4zex:B
7 1nrw:A 285 90 0.1032 0.0912 0.2889 0.24
8 4ap9:A 200 112 0.1230 0.1550 0.2768 0.61 4ap9:B, 4ap9:C, 4ap9:D
9 8k1j:B 242 61 0.0675 0.0702 0.2787 0.80 8k1j:A, 8k1q:A, 8k1q:B, 8k1v:A, 8k1v:B, 8k1z:A, 8k1z:B
10 2pmp:A 160 49 0.0675 0.1062 0.3469 1.2
11 3apt:A 292 112 0.1429 0.1233 0.3214 1.3 3apy:A, 3apy:B, 3apy:C, 3apy:D, 3apy:E, 3apy:F, 3apy:G, 3apy:H, 8eac:A, 7th4:A, 7th4:B, 7th5:A, 7th5:B, 1v93:A
12 3wxx:G 151 66 0.0952 0.1589 0.3636 1.7
13 7mqa:LQ 830 70 0.0754 0.0229 0.2714 1.7 7mq8:LQ, 7mq9:LQ
14 5t62:W 306 55 0.0754 0.0621 0.3455 2.3
15 6h42:A 393 61 0.0754 0.0483 0.3115 2.4 6h42:B, 6h45:A, 6h45:B, 7nq4:A, 8omr:A
16 7pkq:c 135 49 0.0714 0.1333 0.3673 2.7
17 5kf0:A 480 51 0.0714 0.0375 0.3529 2.8 5jry:A, 5kf0:B, 5kf0:C, 5kf0:D
18 5tr1:A 606 64 0.0873 0.0363 0.3438 2.9 5tr1:B
19 6zhh:A 883 137 0.1270 0.0362 0.2336 3.0 6zhf:A, 6zhg:A, 6zhh:B, 6zhh:C, 6zhh:D, 6zhh:E, 6zhh:F, 6zhh:G, 6zhh:H
20 6rv2:D 261 76 0.0873 0.0843 0.2895 3.3 6rv2:A, 6rv2:B, 6rv2:C, 6rv3:A, 6rv3:B, 6rv3:C, 6rv3:D, 6rv4:A, 6rv4:B, 6rv4:C, 6rv4:D
21 1nf2:A 267 71 0.0952 0.0899 0.3380 4.2 1nf2:B, 1nf2:C
22 7r7j:B 574 79 0.1111 0.0488 0.3544 4.5 8h5y:B, 8h5y:A, 8h5z:B, 8h5z:A, 6jde:B, 6jde:A, 7r7j:A
23 6qj6:A 265 55 0.0913 0.0868 0.4182 4.6 6qj6:E, 6rcz:A, 6rcz:E
24 6n8n:W 377 45 0.0675 0.0451 0.3778 5.1 6n8o:W
25 1gye:B 315 118 0.1151 0.0921 0.2458 5.2
26 1plj:A 147 27 0.0437 0.0748 0.4074 5.3
27 6qtz:o 325 45 0.0675 0.0523 0.3778 5.4 6qik:o, 6ri5:o, 6rzz:o, 6s05:o
28 2bvf:A 453 39 0.0595 0.0331 0.3846 6.7 2bvf:B, 2bvg:A, 2bvg:B, 2bvg:C, 2bvg:D, 2bvh:A, 2bvh:B, 2bvh:C, 2bvh:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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