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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MDVRIGQGYDVHQLVEGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDDSRVLLRACAERVKA
AGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG

The query sequence (length=153) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4c8e:A 161 161 1.0000 0.9503 0.9503 1.72e-105 4c8e:C, 4c8e:B, 4c8g:A, 4c8g:C, 4c8g:B, 4c8i:A, 4c8i:B, 4c8i:C, 3f0d:B, 3k2x:A, 3mbm:B
2 3iew:A 160 159 0.8824 0.8438 0.8491 7.90e-93 3f0d:A, 3f0d:C, 3f0d:D, 3f0d:E, 3f0d:F, 3f0e:A, 3f0e:B, 3f0e:C, 3f0f:A, 3f0f:B, 3f0f:C, 3f0g:A, 3f0g:B, 3f0g:C, 3f0g:D, 3f0g:E, 3f0g:F, 3ieq:A, 3ieq:C, 3ieq:B, 3iew:C, 3iew:B, 3ike:A, 3ike:B, 3ike:C, 3ikf:A, 3ikf:B, 3ikf:C, 3jvh:A, 3jvh:B, 3jvh:C, 3k14:A, 3k14:B, 3k14:C, 3k2x:C, 3k2x:B, 3ke1:A, 3ke1:B, 3ke1:C, 5l03:A, 5l03:B, 5l03:C, 5l12:A, 5l12:B, 5l12:C, 3mbm:A, 3mbm:C, 6mwf:A, 6mwf:B, 6mwf:C, 6mwi:A, 6mwi:B, 6mwi:C, 6mwj:A, 6mwj:B, 6mwj:C, 6mwk:A, 6mwk:B, 6mwk:C, 6nmo:A, 6nmo:B, 6nmo:C, 3p0z:A, 3p0z:C, 3p0z:B, 3p10:A, 3p10:C, 3p10:B, 3q8h:A, 3q8h:B, 3q8h:C, 3qhd:A, 3qhd:C, 3qhd:B, 6v3m:A, 6v3m:B, 6v3m:C
3 1t0a:A 158 157 0.5882 0.5696 0.5732 6.90e-59 1t0a:B, 1t0a:C
4 1jn1:A 157 156 0.5948 0.5796 0.5833 2.74e-58 1jn1:B, 1jn1:C, 1vh8:A, 1vh8:B, 1vh8:C, 1vh8:D, 1vh8:E, 1vh8:F, 1vha:A, 1vha:B, 1vha:C, 1vha:D, 1vha:E, 1vha:F
5 5iwx:A 158 155 0.5882 0.5696 0.5806 3.58e-57 5iwx:B, 5iwx:C, 5iwx:D, 5iwx:E, 5iwx:F, 5iwy:A, 5iwy:C, 5iwy:B, 5iwy:D, 5iwy:E, 5iwy:F
6 5b8f:C 164 157 0.5686 0.5305 0.5541 3.32e-55 5b8f:A, 5b8f:B
7 3esj:A 162 158 0.6144 0.5802 0.5949 4.52e-55 2amt:A, 2amt:B, 2amt:C, 2amt:D, 2amt:F, 2amt:E, 3elc:A, 3elc:B, 3elc:C, 3eor:A, 3ern:A, 3ern:B, 3ern:C, 3ern:D, 3ern:E, 3ern:F, 3fba:A, 3ghz:A, 3ghz:B, 3ghz:C, 1gx1:A, 1gx1:C, 1gx1:B, 2gzl:A, 1h47:A, 1h47:B, 1h47:C, 1h47:D, 1h47:E, 1h47:F, 1h48:A, 1h48:F, 1h48:C, 1h48:B, 1h48:D, 1h48:E, 1jy8:A, 1knj:A, 1knk:A, 3t80:A, 3t80:B, 3t80:C, 3t80:D, 3t80:E, 3t80:F, 1u3l:A, 1u3p:A, 1u40:A, 1u43:A, 1yqn:A
8 3fpi:A 161 158 0.5948 0.5652 0.5759 7.90e-55
9 3re3:B 144 151 0.4444 0.4722 0.4503 1.25e-43
10 2pmp:A 160 159 0.4510 0.4313 0.4340 1.06e-40
11 1w55:A 369 148 0.4379 0.1816 0.4527 3.96e-37 1w57:A
12 5esv:G 187 117 0.4379 0.3583 0.5726 5.38e-34 5esv:E, 5esv:F
13 8xkf:C 377 151 0.3595 0.1459 0.3642 9.86e-31 8xhu:A, 8xhu:B, 8xhu:C, 8xkf:A, 8xkf:B, 8xkf:D, 8xkf:F, 8xkf:E
14 4c81:A 156 153 0.3856 0.3782 0.3856 1.35e-28 4c82:A
15 3b6n:A 150 157 0.4183 0.4267 0.4076 5.62e-28
16 1iv2:A 150 153 0.3791 0.3867 0.3791 3.81e-24 1iv2:C, 1iv2:B, 1iv2:D, 1iv2:F, 1iv2:E, 1iv3:A, 1iv3:B, 1iv3:C, 1iv3:D, 1iv3:E, 1iv3:F, 1iv4:A, 1iv4:B, 1iv4:C, 1iv4:D, 1iv4:E, 1iv4:F
17 2uzh:C 155 145 0.3529 0.3484 0.3724 6.59e-20 2uzh:A, 2uzh:B
18 7ezx:e2 248 56 0.1111 0.0685 0.3036 1.1 7ezx:eR, 6kgx:e3, 6kgx:eD, 7y4l:eK, 7y4l:e1, 7y5e:eA, 7y5e:e7, 7y7a:eD, 7y7a:e5, 7y7a:eg, 7y7a:ei
19 2f7a:B 213 125 0.2026 0.1455 0.2480 1.7
20 8sq0:A 1402 37 0.0980 0.0107 0.4054 2.7 8sq0:B, 8sql:A, 8sqm:A
21 1oj7:A 390 48 0.1046 0.0410 0.3333 4.8 1oj7:B, 1oj7:C, 1oj7:D, 4qgs:A
22 1zh1:A 163 69 0.1307 0.1227 0.2899 7.1 3fqm:A, 3fqm:B, 3fqq:A, 3fqq:B, 1zh1:B
23 4bq2:D 726 38 0.0850 0.0179 0.3421 9.9
24 4bq4:A 750 38 0.0850 0.0173 0.3421 9.9 4bq2:A, 4bq2:B, 4bq2:C, 4bq3:A, 4bq3:B, 4bq3:C, 4bq3:D, 4bq4:B, 4bq5:A, 4bq5:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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