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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MDLFQDKVEAFTGPTMGSTYTVKYVRSGDGPAKEVLHGEVEAILGQLDKQLSTYRSDSDVERFNALPAGSCEPMPDMVRE
LVAAGSQLSADSDGAFDLTLEPLLNLSAEDISAARALTGQQHLSIDGDRLCKAVALQLDFNSIAAGYAVDLVIDRLKALG
VQSYLVEITGELKAEGRKPDGSPWRIAIEAPRDDQRVAQKIVELDGMGVSTSGDYRNYFERYSHTLDPQSGQPIEHHLAA
VTVIDKSTLRADGLSTALMVLGPEKGLALAERNGIAAFFVVREGQGFVTTSTKAFDELFGAGV

The query sequence (length=303) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5mgy:H 316 320 0.9868 0.9462 0.9344 0.0 5mgy:B, 5mgy:G, 5mgy:A, 5mgy:C, 5mgy:D, 5mgy:F
2 6nxi:A 309 301 0.4059 0.3981 0.4086 1.73e-77 6nxj:A, 6nxj:B
3 3pnd:C 323 314 0.3861 0.3622 0.3726 5.95e-63 3pnd:A, 3pnd:B, 3pnd:D
4 2o18:C 313 315 0.3663 0.3546 0.3524 4.23e-59 2o18:A, 2o18:B, 2o18:D, 4xgv:A, 4xgv:B, 4xgv:C, 4xgv:D, 4xgw:A, 4xgw:B, 4xgw:C, 4xgw:D, 4xgx:B
5 4xgx:A 290 304 0.3465 0.3621 0.3454 1.29e-52
6 7esa:A 322 261 0.2409 0.2267 0.2797 1.06e-26 7esb:A, 7esc:A, 7f2u:A, 7f2u:B
7 4ifu:A 330 293 0.2970 0.2727 0.3072 2.92e-17 4ifw:A, 4ifx:A, 4ifz:A, 4ig1:A, 7mgt:A, 4xdr:A, 4xdt:A, 4xdu:A
8 5awp:A 596 69 0.0594 0.0302 0.2609 0.88 5awq:A
9 8gjk:C 1032 71 0.0528 0.0155 0.2254 3.0 8gjl:C, 8gk0:C, 8gk4:C
10 7x2n:A 340 124 0.0990 0.0882 0.2419 3.4 7x2s:A, 7x2x:A
11 5dnu:A 267 119 0.0957 0.1086 0.2437 3.8
12 1t7l:A 734 57 0.0561 0.0232 0.2982 4.1 3bq5:B, 3bq6:A, 3bq6:B, 1t7l:B, 1xdj:A, 1xdj:B, 1xpg:A, 1xpg:B, 1xr2:A, 1xr2:B
13 3el3:A 417 68 0.0759 0.0552 0.3382 4.3 3el3:B
14 3bq5:A 709 57 0.0561 0.0240 0.2982 4.7
15 8q9t:A 1075 79 0.0825 0.0233 0.3165 4.9
16 5mc6:h 1121 79 0.0825 0.0223 0.3165 4.9 4a4k:A, 4a4k:C, 4a4k:E, 4a4k:G, 4a4k:I
17 5z7w:B 271 50 0.0594 0.0664 0.3600 6.1 5z7w:A
18 3dbg:A 379 68 0.0693 0.0554 0.3088 7.4 3dbg:B
19 3gr3:A 226 50 0.0462 0.0619 0.2800 9.1 3gr3:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218