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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MATLTQKFHGLLQHPLEPLFLPKNDGTLFYDLPERFLTSRYSPIGQNLANRFGPNSPATGVPPTVVTIKDLDELPDLTFA
TWIKRRDSFSLFNPEHRKAAGKLTKLFLDQPNADRLVDVAAYARDRLNAPLFQYALSVALLHRPDTKSVSVPSLLHLFPD
QFIDPAAQVRMMEEGSIVLDENRMPIPIPMNYTATDAEPEQRMAFFREDIGVNLHHWHWHLVYPASGPPDVVRKDRRGEL
FYYMHQQLLARYQIDRYAQGLGRIEPLANLREPVREAYYPKLLRTSNNRTFCPRYPGMTISDVARSADRLEVRIADIESW
LPRVLEAIDAGFAVSDDGVRVPLDETRGIDVLGNILERSAISINRNLYGDVHNMGHVLLAFIHDPRGTYLESSGVMGGVA
TAMRDPIFYRWHKFIDNIFLRNKARLAPYTMAELSNSNVTLEALETQLDRAGGAVNSFVTFWQRSQVDLRAGIDFSAAGS
AFVSFTHLQCAPFVYRLRINSTARSNRQDTVRIFLLPRQNEQGRPLSFEDRRLLAIELDSFRVNLRPGMNNIVRQSSNSS
VTIPFERTFGNVQSRFCGCGWPAHMLLPKGNANGVEFDLFAMVSRFEDDNANVNAGCDDSYAFCGLRDRVYPSRRAMGFP
FDRRASNGVRSVADFVAPYKNMRLATVTLRFMNTIIDR

The query sequence (length=678) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4yzw:B 682 683 0.9912 0.9853 0.9839 0.0 4yzw:A
2 8jib:E 661 671 0.4735 0.4856 0.4784 0.0 8ji8:A, 8ji8:B, 8ji8:C, 8ji8:D, 8jib:A, 8jib:B, 8jib:C, 8jib:D, 8jib:F, 8jib:G, 8jib:H, 8jib:I, 8jib:J, 8jib:K, 8jib:L
3 3hhs:B 656 668 0.4263 0.4405 0.4326 0.0
4 3hhs:A 669 671 0.4115 0.4170 0.4158 4.33e-177
5 1nol:A 607 592 0.3304 0.3690 0.3784 8.27e-149 1ll1:A, 1lla:A
6 1oxy:A 573 587 0.3260 0.3857 0.3765 3.60e-147
7 3wky:A 655 643 0.2920 0.3023 0.3079 1.08e-96 3wky:B
8 6l8s:A 650 597 0.2625 0.2738 0.2982 2.68e-79 1hc1:A, 1hc1:B, 1hc1:C, 1hc1:D, 1hc1:E, 1hc1:F, 6l8s:B, 6l8s:C
9 1hcy:A 644 619 0.2714 0.2857 0.2973 1.41e-78
10 8cad:A 636 631 0.2493 0.2657 0.2678 7.73e-47 8cad:B, 8cad:C, 8cad:D, 8cad:E, 8cad:F
11 8can:A 683 609 0.2345 0.2328 0.2611 1.13e-43 8can:B, 8can:C, 8can:D, 8can:E, 8can:F
12 3gwj:D 674 619 0.2198 0.2211 0.2407 1.34e-40 3gwj:A, 3gwj:F, 3gwj:B, 3gwj:E, 3gwj:C
13 8ca9:A 680 617 0.2301 0.2294 0.2528 3.42e-35 8ca9:B, 8ca9:C, 8po9:D, 8po9:A, 8po9:B, 8po9:C, 8po9:E, 8po9:F
14 8ca9:D 678 503 0.1814 0.1814 0.2445 5.39e-31 8ca9:E, 8ca9:F
15 5yy2:A 569 591 0.2035 0.2425 0.2335 4.31e-19
16 3dje:B 437 123 0.0472 0.0732 0.2602 1.9 3djd:A, 3djd:B, 3dje:A
17 2j1p:A 276 52 0.0280 0.0688 0.3654 2.8
18 6ln0:A 425 77 0.0369 0.0588 0.3247 2.9
19 1br6:A 268 131 0.0531 0.1343 0.2748 6.1 1br5:A, 5ddz:A, 3ej5:X, 4esi:A, 5gu4:A, 5gu4:B, 3hio:A, 4huo:X, 4hup:X, 4hv3:A, 4hv7:X, 8i7p:A, 1ifs:A, 1ifu:A, 1il3:A, 1il4:A, 1il5:A, 1il9:A, 1j1m:A, 7kc9:D, 7kd0:A, 7kdm:D, 7kdu:A, 4lgr:A, 7mln:A, 7mlo:A, 7mlo:B, 7mlp:A, 7mlt:A, 4mx1:A, 4mx5:X, 1obt:A, 6obg:B, 6ocd:A, 6ocd:C, 2p8n:A, 2pjo:A, 3px8:X, 3px9:X, 4q2v:A, 2r2x:A, 3rti:A, 3rtj:A, 1rzo:A, 1rzo:C, 8t9v:A, 8tab:A, 8tad:A, 6urw:A, 6urx:A, 6ury:A, 7xzs:A, 7xzt:A, 7xzu:A, 7xzw:A, 7y02:A, 7y03:A, 7y05:A, 7y06:A, 7y07:A, 7y08:A, 7y4k:A, 7y4m:A, 4z9k:A
20 6l2u:A 103 78 0.0339 0.2233 0.2949 8.9 6l2u:B
21 8www:A 501 62 0.0236 0.0319 0.2581 9.7 8www:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218