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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LTRLILVLGDQLSDDLPALRAADPAADLVVMAEVMEEGTYVPHHPQKIALILAAMRKFARRLQERGFRVAYSRLDDPDTG
PSIGAELLRRAAETGAREAVATRPGDWRLIEALEAMPLPVRFLPDDRFLCPADEFARWTEGRKQLRMEWFYREMRRRTGL
LMEGDEPAGGKWNFDTENRKPAAPDLLRPRPLRFEPDAEVRAVLDLVEARFPRHFGRLRPFHWATDRAEALRALDHFIRE
SLPRFGDEQDAMLADDPFLSHALLSSSMNLGLLGPMEVCRRAETEWREGRAPLNAVEGFIRQILGWREYVRGIWTLSGPD
YIRSNGLGHSAALPPLYWGKPTRMACLSAAVAQTRDLAYAHHIQRLMVTGNFALLAGVDPAEVHEWYLSVYIDALEWVEA
PNTIGMSQFADHGLLGSKPYVSSGAYIDRMSDYCRGCAYAVKDRTGPRACPFNLLYWHFLNRHRARFERNPRMVQMYRTW
DRMEETHRARVLTEAEAFLGRLHAGEPV

The query sequence (length=508) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3zxs:A 508 508 1.0000 1.0000 1.0000 0.0 3zxs:B, 3zxs:C
2 6dd6:A 512 507 0.5295 0.5254 0.5306 0.0 4dja:A, 5kcm:A, 5kcm:B, 5lfa:A
3 8ijy:A 501 497 0.3996 0.4052 0.4085 3.69e-126
4 8a1h:A 516 511 0.4272 0.4205 0.4247 5.45e-125 7ykn:A
5 7bc4:B 2054 109 0.0610 0.0151 0.2844 0.21
6 8bmw:H 275 35 0.0276 0.0509 0.4000 0.81 8bmw:I
7 6kii:A 485 232 0.0984 0.1031 0.2155 1.6
8 4fcy:A 443 99 0.0591 0.0677 0.3030 2.9
9 1bwk:A 399 66 0.0433 0.0551 0.3333 3.4 7bn7:A, 7bn7:B, 7bn7:C, 7bn7:D, 1bwl:A, 4gbu:A, 4ge8:A, 4gwe:A, 4gxm:A, 4h4i:A, 4h6k:A, 1k02:A, 1k03:A, 4k7v:A, 4k7y:A, 4k8e:A, 4k8h:A, 1oya:A, 1oyb:A, 1oyc:A, 3rnd:A, 3tx9:A, 3txz:A, 4yil:A, 4ync:A
10 4rnu:C 385 66 0.0433 0.0571 0.3333 4.1 4rnu:A, 4rnu:B, 4rnu:D, 4rnv:A, 4rnv:B, 4rnv:C, 4rnv:D, 4rnw:A, 4rnw:B
11 4rnx:A 390 66 0.0433 0.0564 0.3333 4.2 4rnx:B
12 7poa:A 398 82 0.0453 0.0578 0.2805 5.3 7poa:B, 7pob:A, 7pob:D, 7pob:B, 7pob:C, 7poc:A, 7poc:D, 7poc:B, 7poc:C
13 4iof:A 932 48 0.0335 0.0182 0.3542 6.2
14 5mh5:A 308 44 0.0276 0.0455 0.3182 7.5 5mh5:B, 5mh6:A, 5mh6:B, 5mh6:C, 5mh6:D, 5mha:A, 5mha:B
15 3cdz:A 630 42 0.0276 0.0222 0.3333 8.7 3j2q:A
16 2r7e:A 693 41 0.0276 0.0202 0.3415 8.8
17 6mf2:A 1222 42 0.0276 0.0115 0.3333 8.9 4bdv:A, 4bdv:B, 3cdz:B, 3j2q:B, 5k8d:A, 5k8d:B, 2r7e:B
18 7kwo:A 1200 42 0.0276 0.0117 0.3333 9.0

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218