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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LSHCGRAAHCEPLRYNVCLGSALPYGATTTLLAGDSDSQEEAHGKLVLWSGLRNAPRCWAVIQPLLCAVYMPKCENDRVE
LPSRTLCQATRGPCAIVERERGWPDFLRCTPDHFPEGCPNEVQNIKFNSSGQCEAPLVRTDNPKSWYEDVEGCGIQCQNP
LFTEAEHQDMHSYIAAFGAVTGLCTLFTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRADGT
MRFGEPTSSETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSFKALGTTYQPLSGKTSYFHLLTWSLPFVLTVAILAVAQ
VDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSIKSNHPGLLSEKAASKINETMLRLGIFGFLAF
GFVLITFSCHFYDFFNQAEWERSFRDYVLCQANVTIGDCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWTKATLLIWRRT
WCRL

The query sequence (length=484) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6o3c:A 484 484 1.0000 1.0000 1.0000 0.0 6ot0:R, 6xbj:R, 6xbk:R, 6xbl:R, 6xbm:R
2 5v57:A 645 377 0.7562 0.5674 0.9708 0.0 1akq:A, 1akr:A, 1akt:A, 1aku:A, 1akv:A, 1akw:A, 1azl:A, 1bu5:A, 1bu5:B, 1c7e:A, 1c7e:B, 1c7f:A, 1c7f:B, 1f4p:A, 1fx1:A, 2fx2:A, 3fx2:A, 4fx2:A, 5fx2:A, 1i1o:A, 1j8q:A, 1j9e:A, 1j9g:A, 5v56:A, 5v56:B, 5v57:B, 1wsb:A, 1wsw:A, 1xt6:A, 1xyv:A, 1xyy:A, 5yob:A, 5yoc:A, 5yoe:A, 5yog:A
3 5v57:A 645 113 0.2107 0.1581 0.9027 2.84e-60 1akq:A, 1akr:A, 1akt:A, 1aku:A, 1akv:A, 1akw:A, 1azl:A, 1bu5:A, 1bu5:B, 1c7e:A, 1c7e:B, 1c7f:A, 1c7f:B, 1f4p:A, 1fx1:A, 2fx2:A, 3fx2:A, 4fx2:A, 5fx2:A, 1i1o:A, 1j8q:A, 1j9e:A, 1j9g:A, 5v56:A, 5v56:B, 5v57:B, 1wsb:A, 1wsw:A, 1xt6:A, 1xyv:A, 1xyy:A, 5yob:A, 5yoc:A, 5yoe:A, 5yog:A
4 7zi0:A 593 370 0.7417 0.6054 0.9703 0.0 256b:A, 256b:B, 5l7d:A, 5l7i:A, 5l7i:B, 4o9r:A, 4qim:A, 4qin:A, 1qpu:A, 7zi0:B
5 7zi0:A 593 110 0.2107 0.1720 0.9273 4.87e-61 256b:A, 256b:B, 5l7d:A, 5l7i:A, 5l7i:B, 4o9r:A, 4qim:A, 4qin:A, 1qpu:A, 7zi0:B
6 4n4w:A 457 355 0.7107 0.7527 0.9690 0.0 4jkv:A, 4jkv:B
7 6d35:A 581 374 0.6157 0.5129 0.7968 0.0 6d32:A, 5kzv:A, 5kzy:A, 5kzy:B, 5kzz:A, 1lm3:B, 1lm3:D, 1qq3:A
8 6d35:A 581 110 0.1839 0.1532 0.8091 7.95e-54 6d32:A, 5kzv:A, 5kzy:A, 5kzy:B, 5kzz:A, 1lm3:B, 1lm3:D, 1qq3:A
9 8cxo:A 551 247 0.5103 0.4483 1.0000 1.30e-178
10 8cxo:A 551 99 0.2004 0.1760 0.9798 4.47e-59
11 8wm9:A 320 344 0.1901 0.2875 0.2674 3.93e-37 8wm9:B
12 6bd4:A 379 389 0.1963 0.2507 0.2442 2.67e-33
13 6tfb:A 128 116 0.0682 0.2578 0.2845 7.79e-05 4f0a:A, 6tfb:B
14 6c0b:B 121 109 0.0620 0.2479 0.2752 0.013
15 5ury:A 119 110 0.0579 0.2353 0.2545 0.41 5urz:A
16 6z1p:At 183 70 0.0393 0.1038 0.2714 2.9
17 5u77:A 117 24 0.0207 0.0855 0.4167 4.6
18 1ord:A 730 42 0.0310 0.0205 0.3571 7.4 1c4k:A, 1ord:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218