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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGASSVLENFVGRDFLPRGSGIVTRRPLVLQLVNATTEYAEFLHCKG
KKFTDFEEVRLEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKEN
CLILAVSPANSDLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIDGKKDI
TAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKLQSQLLSIEKEVEEYKNFRPDDPARKTKA
LLQMVQQFAVDFEKRIEGSGDQIDTYELSGGARINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMA
FETIVKKQVKKIREPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNT
NHEDFIIRKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQR
NVYKDYRQLELACETQEEVDSWKASFLRAGVYPEMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEF
IFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGNINTT

The query sequence (length=692) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8sxz:c 699 693 0.9957 0.9857 0.9942 0.0 8sxz:b, 8sxz:f, 8sxz:g, 8sz8:b, 8sz8:c, 8sz8:f, 8sz8:g, 8t0k:b, 8t0k:c, 8t0k:f, 8t0k:g, 8t0r:b, 8t0r:c, 8t0r:f, 8t0r:g, 8tym:c, 8tym:f, 8tym:B, 8tym:C, 8tyn:c, 8tyn:f, 8tyn:C, 8tyn:F
2 6dlu:P 747 739 0.9957 0.9224 0.9323 0.0 2aka:B, 5d3q:A, 5d3q:B, 6dlu:B, 6s9a:B, 2x2e:A, 2x2e:D, 2x2f:A, 2x2f:D, 3zyc:A, 3zyc:D
3 7ax3:D2 582 485 0.6994 0.8316 0.9979 0.0 7ax3:B2, 7ax3:B, 7ax3:D, 7ax3:F, 7ax3:H, 7ax3:J, 7ax3:M, 7ax3:O, 7ax3:Q, 7ax3:S, 7ax3:U, 7ax3:W, 7ax3:Y, 7ax3:E2, 7ax3:G2, 7ax3:H2, 7ax3:I2, 7ax3:J2
4 7ax3:D2 582 98 0.1402 0.1667 0.9898 2.57e-56 7ax3:B2, 7ax3:B, 7ax3:D, 7ax3:F, 7ax3:H, 7ax3:J, 7ax3:M, 7ax3:O, 7ax3:Q, 7ax3:S, 7ax3:U, 7ax3:W, 7ax3:Y, 7ax3:E2, 7ax3:G2, 7ax3:H2, 7ax3:I2, 7ax3:J2
5 6s9a:A 312 305 0.4032 0.8942 0.9148 0.0
6 6s9a:A 312 29 0.0405 0.0897 0.9655 1.35e-09
7 5wp9:A 590 492 0.3483 0.4085 0.4898 1.67e-160 8skn:A, 8skn:B, 3w6n:A, 3w6n:B, 3w6o:A, 3w6o:B, 3w6p:A, 3w6p:B, 5wp9:C, 5wp9:E, 5wp9:G, 5wp9:I, 5wp9:K, 5wp9:M, 5wp9:O
8 5wp9:A 590 93 0.0535 0.0627 0.3978 1.19e-12 8skn:A, 8skn:B, 3w6n:A, 3w6n:B, 3w6o:A, 3w6o:B, 3w6p:A, 3w6p:B, 5wp9:C, 5wp9:E, 5wp9:G, 5wp9:I, 5wp9:K, 5wp9:M, 5wp9:O
9 3l43:B 246 255 0.3165 0.8902 0.8588 2.44e-158 3l43:A, 3l43:C, 3l43:D
10 6def:C 368 347 0.2847 0.5353 0.5677 1.07e-130 6def:A, 6def:B, 6def:D, 6di7:A, 6djq:A, 6djq:C, 6djq:D, 6vjf:A, 6vjf:B, 6vjf:C, 6vjf:D
11 6djq:B 330 328 0.2789 0.5848 0.5884 2.92e-127
12 4h1v:A 358 308 0.2457 0.4749 0.5519 4.11e-116
13 3t34:B 341 310 0.2428 0.4927 0.5419 2.01e-109 3t34:A, 3t35:A, 3t35:B, 3t35:C, 3t35:D
14 1jwy:A 1039 306 0.2442 0.1627 0.5523 2.54e-95 4ae3:A, 2aka:A, 7b19:A, 7b1a:A, 3bz7:A, 3bz8:A, 3bz9:A, 1d0x:A, 1d0y:A, 1d0z:A, 1d1a:A, 1d1b:A, 1d1c:A, 1fmw:A, 2jhr:A, 2jj9:A, 1jx2:A, 1lvk:A, 3mjx:A, 3mkd:A, 1mma:A, 1mmd:A, 1mmg:A, 1mmn:A, 1mne:A, 3mnq:A, 3myh:X, 3myk:X, 3myl:X, 4pjk:A, 1vom:A, 1w9i:A, 1w9j:A, 1w9k:A, 1w9l:A, 2x9h:A, 2xel:A, 2xo8:A, 2y8i:X, 1yv3:A, 6z2s:A, 6z7t:A, 6z7t:B, 6z7u:A
15 4p4s:B 336 336 0.1893 0.3899 0.3899 6.29e-64 4p4s:A, 4p4t:A
16 6jsj:A 625 248 0.1488 0.1648 0.4153 2.38e-41 6jsj:B, 6jsj:C
17 8eew:A 766 262 0.1127 0.1018 0.2977 3.07e-24 8eew:B, 8eff:A, 8eff:B, 8eff:C, 8eff:D, 8efr:A, 8efr:B, 8efr:C, 8efr:K, 8efr:D, 8efr:L, 8efr:E, 8efr:M, 8efr:F, 8efr:N, 8efr:G, 8efr:O, 8efr:H, 8efr:P, 8efr:I, 8efr:Q, 8efr:J, 8efr:R, 6jtg:A
18 5oxf:C 601 131 0.0535 0.0616 0.2824 0.027 5oxf:D
19 6u3e:A 397 89 0.0361 0.0630 0.2809 0.028 6u3e:B, 6u3g:A, 6u3g:B
20 6bbp:A 520 91 0.0361 0.0481 0.2747 0.036 2a5d:A, 2a5f:A, 2a5g:A, 6bbq:A, 1e0s:A, 1fgy:A, 1fhw:A, 1fhw:B, 1fhx:A, 1fhx:B, 4fme:C, 4fme:F, 2j5x:A, 2j5x:B, 4kax:A, 4kax:B, 3n5c:A, 3n5c:B, 3pcr:B, 2r09:A, 2r09:B, 2r0d:A, 2r0d:B, 3vhx:A, 3vhx:C, 3vhx:E, 3vhx:G, 2w83:A, 2w83:B, 2w83:E, 7xrd:A, 7xrd:B, 7xrd:C, 7xrd:D
21 1u27:A 119 116 0.0434 0.2521 0.2586 0.058 1u29:A
22 6za0:A 240 86 0.0303 0.0875 0.2442 4.1 6z74:A, 6z74:B, 6z74:C, 6z74:D, 6za0:B, 6za3:A, 6za3:B, 6za7:A, 6za7:B, 6za7:C, 6za7:D, 6zab:A
23 7kjz:A 102 98 0.0347 0.2353 0.2449 4.1 7kjz:B
24 8szi:B 802 54 0.0246 0.0212 0.3148 4.2 9avg:Q, 9axf:Q, 9ayf:Q, 7dd6:A, 7dd6:B, 7dd7:A, 7dd7:B, 7m3j:A, 7m3j:B, 7sil:A, 7sil:B, 7sim:A, 7sim:B, 7sin:A, 7sin:B, 8szf:A, 8szf:B, 8szg:B
25 6vmb:B 503 54 0.0246 0.0338 0.3148 4.3 6fkf:A, 6fkf:C, 6fkf:E, 6fkh:C, 6fkh:E, 6fkh:A, 6fki:E, 6fki:A, 6fki:C, 1kmh:A, 6vmb:A, 6vmb:C, 6vmd:A, 6vmd:B, 6vmd:C, 6vof:A, 6vof:B, 6vof:C, 6vog:A, 6vog:B, 6vog:C, 6voh:A, 6voh:C, 6voh:B, 6voi:A, 6voi:C, 6voi:B, 6voj:A, 6voj:B, 6voj:C, 6vok:A, 6vok:B, 6vok:C, 6vol:A, 6vol:B, 6vol:C, 6vom:A, 6vom:B, 6vom:C, 6von:A, 6von:B, 6von:C, 6voo:A, 6voo:B, 6voo:C
26 6lqs:RP 2180 153 0.0477 0.0151 0.2157 4.8 7d63:RP, 6lqp:RP, 6lqq:RP, 6lqr:RP, 6lqt:RP, 6lqu:RP, 6lqv:RP
27 6ke6:RP 2052 154 0.0477 0.0161 0.2143 4.8
28 5gom:A 407 64 0.0260 0.0442 0.2812 7.8 5gnr:A, 5gof:A, 5gom:B, 5yew:A, 5yew:B, 5yew:C
29 5goe:A 384 64 0.0260 0.0469 0.2812 8.2 5gns:A, 5gnt:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218