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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAY
GCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITN
GGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAM
GAFDKERPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYA
SIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYGGTSQIQRLIVAREHIDKYKN

The query sequence (length=387) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2a1t:C 388 387 0.9948 0.9923 0.9948 0.0 2a1t:A, 2a1t:B, 2a1t:D, 1egc:A, 1egc:B, 1egc:C, 1egc:D, 1egd:A, 1egd:B, 1egd:C, 1egd:D, 1ege:A, 1ege:B, 1ege:C, 1ege:D, 4p13:A, 4p13:B, 4p13:C, 4p13:D, 8sgp:A, 8sgp:B, 8sgp:C, 8sgp:D, 1t9g:A, 1t9g:B, 1t9g:C, 1t9g:D
2 3mdd:A 385 385 0.8837 0.8883 0.8883 0.0 3mdd:B, 3mde:A, 3mde:B, 1udy:A, 1udy:B, 1udy:C, 1udy:D
3 1ukw:A 379 380 0.4729 0.4828 0.4816 1.38e-126 1ukw:B
4 7w0j:E 382 374 0.3850 0.3901 0.3984 7.47e-96 8i4p:A, 8i4r:A, 7w0j:B, 7w0j:C, 7w0j:H
5 3pfd:C 369 361 0.3721 0.3902 0.3989 1.61e-91 3pfd:A, 3pfd:B, 3pfd:D
6 4l1f:A 380 376 0.3953 0.4026 0.4069 2.24e-88 4l1f:B
7 5ol2:F 378 360 0.3928 0.4021 0.4222 6.47e-88 5ol2:C
8 7p9a:A 380 376 0.3876 0.3947 0.3989 1.17e-86 7p98:A, 7p98:B, 7p9a:B, 7p9x:A, 7p9x:B, 7p9x:C, 7p9x:D
9 7y0a:C 387 385 0.3824 0.3824 0.3844 1.19e-85 1jqi:A, 1jqi:B, 8sgs:A, 8sgs:B, 8sgs:C, 8sgs:D, 2vig:A, 2vig:B, 2vig:C, 2vig:D, 2vig:E, 2vig:F, 2vig:G, 2vig:H, 7y0a:A, 7y0a:B, 7y0a:D, 7y0b:A, 7y0b:B, 7y0b:C, 7y0b:D
10 5lnx:D 374 377 0.3850 0.3984 0.3952 1.04e-84 5lnx:A, 5lnx:B, 5lnx:C, 5lnx:E, 5lnx:F, 5lnx:G, 5lnx:H
11 4n5f:A 378 375 0.3669 0.3757 0.3787 1.59e-82 4n5f:B
12 1buc:A 383 378 0.4005 0.4047 0.4101 2.05e-80 1buc:B
13 6fah:D 379 375 0.3669 0.3747 0.3787 4.51e-79 6fah:C
14 2dvl:A 370 375 0.3928 0.4108 0.4053 1.71e-78 2dvl:B
15 2jif:A 381 378 0.3618 0.3675 0.3704 1.60e-77 2jif:C, 2jif:B, 2jif:D
16 4m9a:B 376 375 0.3643 0.3750 0.3760 2.24e-76 4m9a:A
17 2z1q:B 549 390 0.3695 0.2605 0.3667 1.82e-75 2z1q:A
18 1rx0:A 384 378 0.3282 0.3307 0.3360 1.46e-74 1rx0:C, 1rx0:B, 1rx0:D
19 4kto:A 377 380 0.3592 0.3687 0.3658 3.24e-74 4kto:C, 4kto:B, 4kto:D
20 8sgr:A 393 379 0.3411 0.3359 0.3483 9.80e-74 1ivh:A, 1ivh:B, 1ivh:C, 1ivh:D, 8sgr:B, 8sgr:C, 8sgr:D
21 4iv6:B 383 379 0.3385 0.3420 0.3456 7.28e-73 4iv6:A
22 2d29:A 386 386 0.3902 0.3912 0.3912 9.77e-71 2d29:B
23 3mpi:C 395 384 0.3488 0.3418 0.3516 1.22e-69 3mpi:A, 3mpi:B, 3mpi:D, 3mpj:B, 3mpj:A, 3mpj:D, 3mpj:E, 3mpj:F, 3mpj:G
24 7szv:A 372 372 0.3385 0.3522 0.3522 2.20e-69 7szv:B
25 3nf4:A 369 372 0.3514 0.3686 0.3656 1.88e-67 3nf4:B
26 8w0t:A 398 381 0.3230 0.3141 0.3281 2.25e-67 8w0t:B, 8w0t:C, 8w0t:D, 8w0u:A, 8w0u:B, 8w0u:C, 8w0u:D, 8w0z:A, 8w0z:B, 8w0z:C, 8w0z:D, 8w0z:E, 8w0z:F, 8w0z:G, 8w0z:H
27 2pg0:A 380 374 0.3385 0.3447 0.3503 2.02e-65 2pg0:B
28 3r7k:A 378 375 0.3411 0.3492 0.3520 3.83e-65 3r7k:B, 3r7k:C, 3r7k:D
29 3owa:C 587 396 0.3514 0.2317 0.3434 5.69e-64 3owa:A, 3owa:B, 3owa:D
30 6es9:A 545 376 0.3333 0.2367 0.3431 1.48e-63 6es9:B
31 5idu:C 405 388 0.3463 0.3309 0.3454 1.80e-63 5idu:A, 5idu:B, 5idu:D
32 5af7:B 391 381 0.3127 0.3095 0.3176 7.98e-63 5af7:A, 5ahs:A, 5ahs:B, 5ahs:C, 5ahs:E, 5ahs:F, 5ahs:D
33 8phe:A 551 371 0.3307 0.2323 0.3450 6.51e-62 8phe:B, 8phf:A, 8phf:B
34 3oib:A 381 380 0.3333 0.3386 0.3395 1.58e-57 3oib:B, 3p4t:A, 3p4t:B
35 5jsc:A 388 314 0.2868 0.2861 0.3535 1.64e-57 5jsc:B, 5jsc:C, 5jsc:D
36 4irn:A 378 376 0.2894 0.2963 0.2979 4.15e-57 4irn:B, 4irn:C, 4irn:D, 4irn:E, 4irn:F, 4irn:G, 4irn:H
37 7s7g:A 571 337 0.3075 0.2084 0.3531 6.90e-50 3b96:A, 2uxw:A
38 8ca1:B 589 337 0.2997 0.1969 0.3442 7.04e-50 8ca1:A
39 2eba:A 380 376 0.3075 0.3132 0.3165 4.90e-49 2eba:D, 2eba:C, 2eba:E, 2eba:F, 2eba:G, 2eba:H, 2eba:I
40 7xp7:B 376 370 0.2972 0.3059 0.3108 1.46e-45 7xp7:A, 7xp7:C, 7xp7:D
41 6cxt:B 372 383 0.2765 0.2876 0.2794 9.98e-42 6cy8:B
42 3sf6:A 387 383 0.2842 0.2842 0.2872 6.71e-41
43 6u1v:B 389 394 0.2817 0.2802 0.2766 1.23e-40 6u1v:A, 6u1v:C, 6u1v:D
44 6af6:A 383 382 0.2610 0.2637 0.2644 8.32e-38 5zw2:A, 5zw7:A, 5zw8:A
45 3gqt:C 385 375 0.2791 0.2805 0.2880 2.39e-37 3d6b:C, 3eon:C, 3gnc:A, 3gnc:B, 3gnc:C, 3gnc:D, 3gqt:A, 3gqt:B
46 2r0m:A 390 377 0.2687 0.2667 0.2759 5.05e-37 2r0n:A, 1siq:A, 1sir:A
47 4hr3:A 407 407 0.2972 0.2826 0.2826 7.73e-37
48 2ix6:A 416 379 0.2687 0.2500 0.2744 1.07e-36 2ix5:A, 2ix5:B, 2ix5:C, 2ix5:D, 2ix6:C, 2ix6:F, 2ix6:B, 2ix6:E, 2ix6:D
49 3swo:A 388 383 0.2481 0.2474 0.2507 1.15e-32 3swo:D, 3swo:B, 3swo:C
50 3mkh:A 426 408 0.2946 0.2676 0.2794 6.22e-31 3mkh:B, 3mkh:C, 3mkh:D
51 2wbi:B 398 402 0.2636 0.2563 0.2537 6.26e-30 2wbi:A
52 1r2j:A 353 360 0.2455 0.2691 0.2639 1.07e-28
53 4x28:A 386 385 0.2610 0.2617 0.2623 2.22e-27 4x28:B
54 8ciw:A 555 381 0.2687 0.1874 0.2730 7.12e-27 8ciw:B
55 3d9d:A 432 421 0.2532 0.2269 0.2328 1.32e-22 2c0u:A, 2c0u:B, 2c0u:C, 2c0u:D, 2c12:A, 2c12:B, 2c12:C, 2c12:D, 2c12:E, 2c12:F, 3d9d:B, 3d9d:C, 3d9d:D, 3d9e:A, 3d9e:B, 3d9e:C, 3d9e:D, 3d9f:A, 3d9f:B, 3d9f:C, 3d9f:D, 3d9g:A, 3d9g:B, 3d9g:C, 3d9g:D, 3fcj:A, 3fcj:B, 3fcj:C, 3fcj:D, 2reh:A, 2reh:B, 2reh:C, 2reh:D, 2zaf:A, 2zaf:B, 2zaf:C, 2zaf:D
56 6wy8:B 384 284 0.1938 0.1953 0.2641 1.06e-18 6wy8:D, 6wy9:A
57 6kse:A 607 310 0.2222 0.1417 0.2774 1.11e-17 6kse:B
58 6ksa:B 611 315 0.2222 0.1408 0.2730 2.11e-16 6kpt:A, 6kpt:B, 6kri:A, 6kri:B, 6ks9:A, 6ks9:B, 6ksa:A, 6ksb:A, 6ksb:B, 6lpy:A, 6lpy:B, 6lq0:A, 6lq0:B, 6lq1:A, 6lq1:B, 6lq2:A, 6lq2:B, 6lq3:A, 6lq3:B, 6lq4:A, 6lq4:B, 6lq5:A, 6lq5:B, 6lq6:A, 6lq6:B, 6lq7:A, 6lq7:B, 6lq8:A, 6lq8:B
59 8hk0:B 379 394 0.2455 0.2507 0.2411 6.04e-16 8hk0:A
60 6sd8:X 503 275 0.1809 0.1392 0.2545 1.22e-15 6sd8:A, 6sda:A, 6sda:B
61 4xvx:B 373 277 0.1835 0.1903 0.2563 5.40e-15 4xvx:A
62 5z8t:A 395 353 0.2326 0.2278 0.2550 7.31e-15 5z8t:B, 5z8t:C
63 4kcf:A 407 358 0.2171 0.2064 0.2346 1.41e-12 3m9v:A
64 5ez3:B 541 268 0.1809 0.1294 0.2612 1.54e-12 5ez3:A, 5ez3:C, 5ez3:D
65 3u33:A 540 274 0.1731 0.1241 0.2445 2.09e-11 3djl:A, 3u33:B, 3u33:C, 3u33:D, 3u33:E, 3u33:F, 3u33:G, 3u33:H, 3u33:I, 3u33:J, 3u33:K, 3u33:L
66 6wy8:C 364 386 0.2429 0.2582 0.2435 2.68e-11 6wy8:A, 6wy9:B
67 4x28:D 364 381 0.2093 0.2225 0.2126 1.12e-10 4x28:C
68 1w07:B 658 204 0.1344 0.0790 0.2549 4.38e-08 1w07:A
69 4y9j:B 593 329 0.1990 0.1298 0.2340 1.11e-07 4y9j:A, 4y9l:A, 4y9l:B
70 2fon:B 656 279 0.1731 0.1021 0.2401 1.16e-07 2fon:A, 2fon:C
71 5ys9:A 692 177 0.1292 0.0723 0.2825 1.74e-07 5ys9:B
72 4zyj:D 392 356 0.2171 0.2143 0.2360 5.18e-07 4zyj:A, 4zyj:B, 4zyj:C
73 5k3i:A 661 207 0.1240 0.0726 0.2319 4.74e-05 5k3i:B, 5k3i:C, 5k3i:D, 5k3i:E, 5k3i:F, 5k3i:G, 5k3i:H
74 5y9d:A 687 177 0.1163 0.0655 0.2542 6.62e-05 5y9d:B
75 7q86:A 612 208 0.1395 0.0882 0.2596 0.010 7q86:B
76 1is2:A 637 198 0.1266 0.0769 0.2475 0.020 2ddh:A, 1is2:B
77 5xdc:B 402 271 0.1602 0.1542 0.2288 0.037 5xdb:A, 5xdb:B, 5xdb:C, 5xdb:D, 5xdc:A, 5xdc:C, 5xdc:D, 5xdd:A, 5xdd:B, 5xdd:C, 5xdd:D, 5xde:A, 5xde:B, 5xde:C, 5xde:D, 5xdg:A, 5xdg:B, 5xdg:C, 5xdg:D
78 4d1j:D 540 65 0.0517 0.0370 0.3077 0.35 4d1j:A, 4d1j:B, 4d1j:C, 4d1j:E, 4d1j:F, 4d1j:G, 4d1j:H, 5jaw:A, 5jaw:D, 5jaw:B, 5jaw:C, 5jaw:E, 5jaw:F, 5jaw:G, 5jaw:H, 8pej:A, 8pej:B, 8pej:C, 8pej:D, 8pej:E, 8pej:F, 8pej:G, 8pej:H, 6tbf:A, 6tbf:B, 6tbf:C, 6tbf:D, 6tbf:E, 6tbf:F, 6tbf:G, 6tbf:H, 6tbg:A, 6tbg:B, 6tbg:C, 6tbg:D, 6tbg:E, 6tbg:F, 6tbg:G, 6tbg:H, 6tbh:A, 6tbh:C, 6tbh:B, 6tbh:D, 6tbh:E, 6tbh:G, 6tbh:F, 6tbh:H, 6tbi:A, 6tbi:B, 6tbi:C, 6tbi:D, 6tbi:E, 6tbi:F, 6tbi:G, 6tbi:H, 6tbj:A, 6tbj:B, 6tbj:C, 6tbj:D, 6tbj:E, 6tbj:F, 6tbj:G, 6tbj:H, 6tbk:A, 6tbk:B, 6tbk:C, 6tbk:D, 6tbk:E, 6tbk:F, 6tbk:G, 6tbk:H
79 2r66:A 456 60 0.0491 0.0417 0.3167 0.78 2r68:A
80 5k3j:A 662 142 0.0827 0.0483 0.2254 0.79 5k3j:B
81 5tip:A 436 35 0.0336 0.0298 0.3714 1.2 5tip:B, 5tip:C, 5tip:D, 5tiq:A, 5tiq:B
82 3nz2:J 185 19 0.0284 0.0595 0.5789 4.6 3ect:A, 3nz2:A, 3nz2:C, 3nz2:B, 3nz2:D, 3nz2:E, 3nz2:F, 3nz2:G, 3nz2:H, 3nz2:I, 3nz2:K, 3nz2:L
83 7kb7:A 218 45 0.0388 0.0688 0.3333 5.1
84 5ei3:A 191 52 0.0413 0.0838 0.3077 6.5 3am7:A, 4aza:A, 4aza:C, 4bea:A, 5bxv:A, 5bxv:C, 7d6y:A, 4dt6:A, 4dum:A, 5ehc:A, 5eir:A, 1ej1:A, 1ej1:B, 1ej4:A, 1ejh:A, 1ejh:B, 1ejh:C, 1ejh:D, 5ekv:A, 5ekv:C, 7ezw:A, 6gkj:A, 6gkj:B, 6gkj:C, 6gkj:D, 6gkk:A, 6gkk:B, 6gkk:C, 6gkk:D, 6gkl:A, 6gkl:B, 6gkl:C, 6gkl:D, 1ipb:A, 1ipc:A, 5j5o:A, 5j5o:B, 5j5o:C, 5j5o:D, 5j5y:A, 5j5y:B, 1l8b:A, 1l8b:B, 5m7v:A, 5m7v:B, 5m7v:C, 5m7w:A, 5m7w:B, 5m7w:C, 5m7w:D, 5m7x:A, 5m7x:B, 5m7x:C, 5m7x:D, 5m7z:A, 5m7z:B, 5m7z:C, 5m80:A, 5m80:B, 5m81:A, 5m81:B, 5m81:C, 5m81:D, 5m83:A, 5m83:B, 5m84:A, 5m84:B, 7meu:A, 7meu:B, 5osx:A, 5osx:B, 8sx4:A, 8sx4:B, 5t46:A, 5t46:C, 4tpw:A, 4tpw:B, 4tqb:A, 4tqb:B, 4tqc:A, 4tqc:B, 6u06:A, 6u06:B, 6u06:C, 6u06:D, 6u09:A, 6u09:B, 6u09:C, 6u09:D, 3u7x:A, 3u7x:B, 2v8w:A, 2v8w:E, 2v8x:A, 2v8x:E, 2v8y:A, 2v8y:E, 2w97:A, 2w97:B, 1wkw:A, 7xtp:A, 7xtp:B, 6ylr:A, 6ylr:B, 6ylt:A, 6ylt:B, 6ylt:C, 6ylt:D, 6ylv:A, 6ylv:B, 6ylv:C, 6ylv:D, 5zjy:A, 5zjz:A, 5zk5:A, 5zk7:A, 5zk7:B, 5zk9:A, 5zml:A
85 5erp:A 443 48 0.0362 0.0316 0.2917 7.1 5erp:B
86 1z7e:D 644 41 0.0413 0.0248 0.3902 8.1 2bln:A, 2bln:B, 5j63:A, 5j63:B, 5j63:C, 5j63:D, 1z7e:A, 1z7e:B, 1z7e:C, 1z7e:E, 1z7e:F
87 8dhl:B 853 74 0.0568 0.0258 0.2973 9.4 8dhl:A
88 7aih:G 365 72 0.0491 0.0521 0.2639 9.7 7am2:G, 7ane:G

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218