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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KRKGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGIREILIISTPQDTPRFQQLLGDGSNWGLDLQYAV
QPSPDGLAQAFLIGESFIGNDLSALVLGDNLYYGHDFHELLGSASQRQTGASVFAYHVLDPERYGVVEFDQGGKAISLEE
KPLEPKSNYAVTGLYFYDQQVVDIARDLKPSPRGELEITDVNRAYLERGQLSVEIMGRGYAWLDTGTHDSLLEAGQFIAT
LENRQGLKVACPEEIAYRQKWIDAAQLEKLAAPLAKNGYGQYLKRLLTETVY

The query sequence (length=292) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4b2x:B 302 292 1.0000 0.9669 1.0000 0.0 4arw:A, 4arw:B, 4arw:C, 4arw:D, 4asj:A, 4asj:B, 4asj:C, 4asj:D, 4asy:A, 4asy:B, 4asy:C, 4asy:D, 4b2w:A, 4b2w:B, 4b2w:C, 4b2w:D, 4b2x:A, 4b2x:C, 4b2x:D, 4b3u:A, 4b3u:B, 4b3u:C, 4b3u:D, 4b42:A, 4b42:B, 4b42:C, 4b42:D, 4b4b:A, 4b4b:B, 4b4b:C, 4b4b:D, 4b4g:A, 4b4g:B, 4b4g:C, 4b4g:D, 4b4m:A, 4b4m:B, 4b4m:C, 4b4m:D, 4b5b:A, 4b5b:B, 4b5b:C, 4b5b:D, 5fts:A, 5fts:B, 5fts:C, 5fts:D, 5ftv:A, 5ftv:B, 5ftv:C, 5ftv:D, 5fu0:A, 5fu0:B, 5fu0:C, 5fu0:D, 5fu8:A, 5fu8:B, 5fu8:C, 5fu8:D, 5fuh:A, 5fuh:B, 5fuh:C, 5fuh:D, 1fxo:A, 1fxo:C, 1fxo:B, 1fxo:D, 1fxo:E, 1fxo:H, 1fxo:F, 1fxo:G, 5fye:A, 5fye:B, 5fye:C, 5fye:D, 1g0r:A, 1g0r:B, 1g0r:C, 1g0r:D, 1g0r:E, 1g0r:G, 1g0r:H, 1g1l:A, 1g1l:C, 1g1l:B, 1g1l:D, 1g1l:E, 1g1l:H, 1g1l:F, 1g1l:G, 1g23:A, 1g23:B, 1g23:C, 1g23:D, 1g23:E, 1g23:F, 1g23:G, 1g23:H, 1g2v:A, 1g2v:C, 1g2v:B, 1g2v:D, 1g2v:E, 1g2v:G, 1g2v:F, 1g2v:H, 1g3l:A, 1g3l:C, 1g3l:B, 1g3l:D, 6t37:A, 6t37:B, 6t37:C, 6t37:D, 6t38:A, 6t38:B, 6t38:C, 6t38:D, 6tqg:A, 6tqg:B, 6tqg:C, 6tqg:D, 3zlk:A, 3zlk:B, 3zlk:C, 3zlk:D, 3zll:A, 3zll:B, 3zll:C, 3zll:D
2 1h5s:B 291 284 0.7500 0.7526 0.7711 6.82e-168 1h5r:A, 1h5r:B, 1h5r:C, 1h5r:D, 1h5s:A, 1h5s:D, 1h5s:C, 1h5t:A, 1h5t:D, 1h5t:B, 1h5t:C, 1iim:A, 1iim:B, 1iin:A, 1iin:B, 1iin:C, 1iin:D, 1mp3:A, 1mp3:B, 1mp4:A, 1mp4:B, 1mp5:A, 1mp5:B, 1mp5:C, 1mp5:D, 3pkp:A, 3pkp:B, 3pkp:C, 3pkp:D, 3pkp:I, 3pkp:J, 3pkp:K, 3pkp:L, 3pkq:A, 3pkq:B, 3pkq:C, 3pkq:D
3 5ify:A 293 290 0.7500 0.7474 0.7552 1.46e-166 5ify:B, 5ify:C, 5ify:D, 5ify:E, 5ify:F
4 6n0u:A 295 290 0.7397 0.7322 0.7448 3.05e-164 6n0u:B, 6n0u:C, 6n0u:D
5 4ho9:A 294 284 0.6952 0.6905 0.7148 5.59e-152 4ho3:A, 4ho4:A, 4ho5:A, 4ho5:B, 4ho6:A, 4ho8:A, 4ho8:B, 4ho8:C, 4ho8:D, 4ho9:B, 4hoc:A, 4hoc:B
6 1mc3:A 291 285 0.6438 0.6460 0.6596 7.83e-141 1mc3:B
7 1lvw:A 295 284 0.6027 0.5966 0.6197 8.30e-129 1lvw:B, 1lvw:C, 1lvw:D
8 6b5e:B 286 285 0.6062 0.6189 0.6211 1.77e-124 6b5e:A, 6b5e:C, 6b5e:D, 6b5e:E, 6b5e:F, 6b5e:G, 6b5e:H, 6b5k:A, 6b5k:B
9 3hl3:A 246 232 0.3630 0.4309 0.4569 1.89e-60 4ecm:A
10 3juk:A 265 261 0.2568 0.2830 0.2874 5.87e-21 3juk:B, 3juk:C, 3juk:D
11 2ggq:A 401 235 0.2158 0.1571 0.2681 2.37e-18 5z09:A, 5z09:B, 5z09:C, 5z09:D
12 8f73:E 281 277 0.2637 0.2740 0.2780 4.59e-18 8f73:A, 8f73:B, 8f73:C, 8f73:D, 8f73:F, 8f73:G, 8f73:H
13 8b6d:A 291 247 0.2226 0.2234 0.2632 2.11e-16 8b68:A, 8b6d:B
14 5i1f:A 290 241 0.2158 0.2172 0.2614 4.22e-15
15 7whs:A 366 242 0.2123 0.1694 0.2562 5.04e-14 7whs:B, 7whs:C, 7whs:D, 7whs:E, 7whs:F, 7wht:A, 7wht:B, 7wht:C, 7wht:D, 7wht:E, 7wht:F
16 5ve7:A 282 242 0.2192 0.2270 0.2645 1.54e-13
17 2pa4:B 299 238 0.2260 0.2207 0.2773 1.75e-12 2pa4:A, 2pa4:C, 2pa4:D
18 2ux8:G 288 232 0.2055 0.2083 0.2586 4.88e-12 2ux8:B, 2ux8:C, 2ux8:D, 2ux8:E, 2ux8:F
19 4y7u:A 224 238 0.2329 0.3036 0.2857 1.06e-11 4y7v:A
20 7x8k:B 367 192 0.1712 0.1362 0.2604 6.08e-11 7x8k:A, 7x8k:D
21 6k8d:A 290 239 0.2089 0.2103 0.2552 8.90e-11 6ikz:B, 6k8d:B, 6k8d:C, 6k8d:D, 6knj:A, 6knj:B, 6knl:A, 6knl:B
22 7d72:K 360 251 0.1986 0.1611 0.2311 1.48e-10 7d72:I, 7d72:E, 7d72:F, 7d72:G, 7d72:H, 7d72:J, 7d72:L, 7d73:E, 7d73:F, 7d73:G, 7d73:I, 7d73:J, 7d73:K, 7d73:L, 7d73:H, 7d74:E, 7d74:F, 7d74:G, 7d74:H, 7d74:I, 7d74:J, 7d74:K, 7d74:L
23 2ux8:A 255 138 0.1267 0.1451 0.2681 1.74e-08 2ux8:H
24 1jyl:A 228 51 0.0856 0.1096 0.4902 5.36e-06 1jyl:B, 1jyl:C, 1jyl:D
25 7d72:A 407 238 0.2158 0.1548 0.2647 1.02e-05 7d72:B, 7d72:C, 7d72:D, 7d73:A, 7d73:B, 7d73:C, 7d73:D, 7d74:A, 7d74:D, 7d74:B, 7d74:C
26 6r8u:A 425 305 0.2466 0.1694 0.2361 1.04e-04 5l6s:C, 5l6s:G, 5l6s:I, 5l6s:L, 5l6v:A, 5l6v:E, 5l6v:G, 5l6v:H, 5l6v:J, 5l6v:K, 5l6v:N, 5l6v:B, 5l6v:C, 5l6v:D, 5l6v:F, 5l6v:L, 5l6v:M, 5l6v:O, 5l6v:P, 6r8b:D, 6r8b:B, 6r8b:A, 6r8b:C, 6r8u:B, 6r8u:D, 6r8u:C, 6shj:D, 6shj:A, 6shj:B, 6shj:C, 6shn:D, 6shn:C, 6shq:A, 6shq:D, 6shq:C, 6shq:B, 6si8:A, 6si8:B, 6si8:D, 6si8:C
27 4jd0:A 245 194 0.1541 0.1837 0.2320 3.14e-04
28 5l6v:I 400 191 0.1712 0.1250 0.2618 5.94e-04
29 1wvc:A 254 52 0.0582 0.0669 0.3269 0.002 1tzf:A
30 6jlz:I 430 55 0.0582 0.0395 0.3091 0.004
31 6xhq:A 237 52 0.0685 0.0844 0.3846 0.006 6xhq:B, 6xhs:B, 6xhs:E, 6xht:A, 6xht:B, 6xht:E, 6xht:F
32 6jq8:A 225 158 0.1336 0.1733 0.2468 0.006
33 6jly:E 414 66 0.0753 0.0531 0.3333 0.007 6jly:F, 6jlz:E, 6jlz:F
34 3rsb:B 185 64 0.0616 0.0973 0.2812 0.13 3rsb:A, 3rsb:C, 3rsb:D
35 1yp3:C 435 169 0.1473 0.0989 0.2544 0.17 1yp2:A, 1yp2:B, 1yp2:C, 1yp2:D, 1yp3:A, 1yp3:B, 1yp3:D, 1yp4:A, 1yp4:B, 1yp4:C
36 2x65:A 334 108 0.1027 0.0898 0.2778 0.17 2x5z:A, 2x5z:B, 2x60:A, 2x60:B, 2x65:B
37 4e1k:A 450 158 0.1336 0.0867 0.2468 0.62 4knr:A, 4knx:A, 4kpx:A, 4kpz:A, 4kql:A, 2v0i:A, 2v0j:A, 2v0k:A, 2v0l:A, 2vd4:A, 2w0v:A, 2w0w:A
38 6pd2:C 616 51 0.0548 0.0260 0.3137 0.89 6pd1:A, 6pd1:B, 6pd1:D, 6pd2:A, 6pd2:B, 6pd2:D
39 1vpa:A 221 55 0.0548 0.0724 0.2909 1.9 1vpa:B
40 4fce:A 441 49 0.0514 0.0340 0.3061 2.8
41 5tew:A 333 21 0.0377 0.0330 0.5238 2.9
42 8day:A 398 27 0.0411 0.0302 0.4444 8.7 8daz:A, 8daz:C, 8db0:A, 8db0:B, 8db0:C, 8db0:D, 8db1:A
43 2fgh:A 721 122 0.1164 0.0472 0.2787 9.1 3a5l:S, 3a5m:S, 3a5n:S, 3a5o:S, 1c0f:S, 1c0g:S, 4cbu:G, 4cbw:G, 4cbx:G, 3ci5:G, 3cip:G, 3cjb:G, 3cjc:G, 1d4x:G, 1dej:S, 1eqy:S, 1esv:S, 2ff3:A, 2ff6:G, 3ffk:A, 3ffk:D, 2fgh:B, 2fh1:A, 2fh1:B, 2fh1:C, 2fh2:A, 2fh2:B, 2fh2:C, 2fh3:A, 2fh3:B, 2fh3:C, 1h1v:G, 6i4d:G, 6i4e:G, 6i4f:G, 6i4g:G, 6i4g:H, 6i4h:G, 6i4i:G, 6i4j:G, 6i4k:G, 6i4l:G, 6i4m:G, 6lje:A, 6lje:B, 6ljf:A, 6ljf:B, 1mdu:A, 1mdu:D, 5mvv:G, 1nlv:G, 1nm1:G, 1nmd:G, 1nph:A, 1p8x:A, 1p8x:B, 1p8x:C, 1p8z:G, 4pkh:E, 4pkh:J, 1rgi:G, 3tu5:B, 5ubo:S, 1yag:G, 1yvn:G, 5zz0:G, 5zz0:A
44 2q6f:B 295 30 0.0377 0.0373 0.3667 10.0 2q6f:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218