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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KPLNIVYIMTDDHTAQMMSCYDTRYMETPNLDRIAEEGVLFTNSFVANSLSGPSRACMITGKHSCANKFYDNTTCVFDSA
QQTFPKLLQKAGYQTALVGKWHLESLPSGFNYWEIVPGQGDYYNPDFITQNNDTIRKHGYITNLITDDAIDWMEHKRDLD
KPFCLLIHHKAIHRNWLADTCNLALYEDKTFPLPDNFFDDYEGRPAAASQEMSIAKDMDMIYDLKMLRPDKDSRLKALYE
KYIGRMDKAQRAAWDKFYDPIIADFYRQNLQGKELANWKFQRYMRDYMKTVKSLDDNVGRVFDYLKKKGLLDNTLVVYTS
DQGFYMGEHGWFDKRFMYEESMRTPLIMRLPKGFDRRGKITEMVQNIDYAPTFLELAGAPVPEDIHGVSLVPLLKGEHPQ
DWRTALYYHFYEYPAEHMVKRHYGIRTERYKLIHFYNNINWWELYDLQADPTEMHNLYGQPEYESIAEELKVEMEKLQEQ
YNDPVRFSPERDKE

The query sequence (length=494) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7p24:AAA 494 494 1.0000 1.0000 1.0000 0.0
2 5g2v:A 494 494 0.5283 0.5283 0.5283 0.0
3 7ebp:A 526 507 0.4332 0.4068 0.4221 1.32e-135 7ebp:B, 7ebq:A
4 7lj2:A 507 521 0.3745 0.3649 0.3551 5.89e-106 7lha:A, 7lha:B, 7lj2:B
5 7sno:A 506 531 0.3704 0.3617 0.3446 2.54e-99
6 7oz8:AAA 474 483 0.2672 0.2785 0.2733 1.66e-36
7 4upi:A 548 504 0.2672 0.2409 0.2619 2.42e-35
8 2vqr:A 512 489 0.2490 0.2402 0.2515 3.23e-35
9 2w8s:B 513 525 0.2692 0.2593 0.2533 4.29e-35 2w8s:A, 2w8s:C, 2w8s:D
10 6hr5:A 376 210 0.1417 0.1862 0.3333 3.96e-32
11 6hr5:A 376 177 0.1012 0.1330 0.2825 3.58e-15
12 7pth:A 517 482 0.2672 0.2553 0.2739 4.04e-30 6fny:A, 6fny:B, 6fny:C, 6fny:D, 6fny:E, 6fny:F, 6fny:G, 6fny:H, 6g5z:A, 6g5z:B, 6g5z:C, 6g5z:D, 6g60:A, 6g60:B, 6g60:C, 6g60:D, 7pth:B, 7pth:C, 7pth:D, 7ptj:A, 7ptj:B, 7ptj:C, 7ptj:D
13 7all:AAA 498 530 0.2814 0.2791 0.2623 1.45e-28
14 6ust:C 464 487 0.2449 0.2608 0.2485 7.32e-26 6ust:A, 6ust:B, 6ust:D
15 7ana:AAA 475 506 0.2348 0.2442 0.2292 1.89e-24 7ana:BBB, 7anb:AAA, 7anb:BBB
16 3b5q:B 467 490 0.2409 0.2548 0.2429 4.94e-24 3b5q:A, 5g2t:A, 5g2t:B, 5g2t:C, 5g2t:D, 5g2u:A
17 4upl:A 555 192 0.1316 0.1171 0.3385 2.81e-23 4upl:C
18 4upl:A 555 163 0.0891 0.0793 0.2699 4.10e-10 4upl:C
19 7an1:AAA 483 528 0.2632 0.2692 0.2462 3.52e-23 7oqd:AAA
20 4cys:A 534 555 0.2611 0.2416 0.2324 7.48e-22 5aj9:A, 5aj9:B, 4cxk:A, 4cxk:B, 4cxs:A, 4cxs:B, 4cxu:A, 4cxu:B, 4cyr:A, 4cyr:B, 4cys:B, 1hdh:A, 1hdh:B
21 5fql:A 507 536 0.2490 0.2426 0.2295 2.29e-21 6ioz:A
22 7stt:A 445 172 0.1194 0.1326 0.3430 7.14e-21 7stu:A, 7stv:A
23 7stt:A 445 190 0.1073 0.1191 0.2789 5.62e-16 7stu:A, 7stv:A
24 4uph:A 504 182 0.1174 0.1151 0.3187 8.24e-20 4uph:B, 4uph:C, 4uph:D
25 4uph:A 504 96 0.0526 0.0516 0.2708 1.21e-06 4uph:B, 4uph:C, 4uph:D
26 7p26:AAA 484 422 0.1964 0.2004 0.2299 1.40e-19
27 6j66:B 476 213 0.1377 0.1429 0.3192 2.38e-19 6j66:A
28 6j66:B 476 217 0.0972 0.1008 0.2212 6.25e-08 6j66:A
29 8di0:B 426 487 0.2389 0.2770 0.2423 4.31e-19
30 7ozc:AAA 485 348 0.1721 0.1753 0.2443 7.33e-19
31 4fdi:A 494 264 0.1498 0.1498 0.2803 9.19e-19 4fdi:B, 4fdj:A, 4fdj:B
32 4fdi:A 494 123 0.0830 0.0830 0.3333 4.65e-08 4fdi:B, 4fdj:A, 4fdj:B
33 6s20:C 480 110 0.0850 0.0875 0.3818 4.23e-18
34 6s20:C 480 225 0.1113 0.1146 0.2444 5.99e-06
35 6psm:C 448 225 0.1275 0.1406 0.2800 3.09e-17 6prm:A, 6prm:B, 6prm:C, 6prm:D, 6psm:A, 6psm:B, 6psm:D, 6psm:E, 6psm:F, 6pso:B, 6pso:A
36 6psm:C 448 172 0.1032 0.1138 0.2965 1.81e-09 6prm:A, 6prm:B, 6prm:C, 6prm:D, 6psm:A, 6psm:B, 6psm:D, 6psm:E, 6psm:F, 6pso:B, 6pso:A
37 9fvt:A 519 137 0.1032 0.0983 0.3723 8.34e-17 9fvt:B, 9fvt:C, 9fvt:D
38 9fvt:A 519 128 0.0769 0.0732 0.2969 5.57e-10 9fvt:B, 9fvt:C, 9fvt:D
39 6pt4:B 473 202 0.1275 0.1332 0.3119 3.43e-16 6pt4:A, 6pt6:B, 6pt6:A, 6pt9:A, 6pt9:B, 6ptk:A, 6ptk:B, 6ptk:C, 6ptk:D
40 6pt4:B 473 241 0.1154 0.1205 0.2365 2.22e-08 6pt4:A, 6pt6:B, 6pt6:A, 6pt9:A, 6pt9:B, 6ptk:A, 6ptk:B, 6ptk:C, 6ptk:D
41 8eg3:A 554 155 0.0992 0.0884 0.3161 4.70e-16 1p49:A
42 8eg3:A 554 169 0.1113 0.0993 0.3254 1.01e-13 1p49:A
43 6b0j:A 452 218 0.1113 0.1217 0.2523 1.24e-15 6b0j:B, 6b0j:C, 6b0k:A, 6b0k:B, 6b0k:C, 6b1v:A, 6b1v:B, 6b1v:C, 6bia:A, 6bia:B, 6bia:C
44 6b0j:A 452 201 0.1113 0.1217 0.2736 5.71e-11 6b0j:B, 6b0j:C, 6b0k:A, 6b0k:B, 6b0k:C, 6b1v:A, 6b1v:B, 6b1v:C, 6bia:A, 6bia:B, 6bia:C
45 7oze:AAA 487 536 0.2530 0.2567 0.2332 1.87e-15 7oze:EEE, 7oze:FFF, 7oze:GGG
46 6uss:A 485 192 0.1093 0.1113 0.2812 3.50e-14 6uss:B
47 6uss:A 485 231 0.1154 0.1175 0.2468 1.63e-09 6uss:B
48 6s21:A 486 228 0.1316 0.1337 0.2851 8.74e-14 6s21:B, 6s21:C
49 4miv:A 484 254 0.1275 0.1302 0.2480 1.62e-13 4mhx:A, 4mhx:B, 4miv:B, 4miv:C, 4miv:D, 4miv:E, 4miv:F, 4miv:G, 4miv:H
50 4miv:A 484 107 0.0729 0.0744 0.3364 3.98e-05 4mhx:A, 4mhx:B, 4miv:B, 4miv:C, 4miv:D, 4miv:E, 4miv:F, 4miv:G, 4miv:H
51 1n2l:A 483 116 0.0850 0.0870 0.3621 2.97e-13 1auk:A, 1e1z:P, 1e2s:P, 1e33:P, 1e3c:P, 1n2k:A
52 1n2l:A 483 203 0.1235 0.1263 0.3005 4.92e-13 1auk:A, 1e1z:P, 1e2s:P, 1e33:P, 1e3c:P, 1n2k:A
53 7oza:CCC 488 214 0.1113 0.1127 0.2570 1.07e-12 7oza:AAA
54 7oza:CCC 488 231 0.1113 0.1127 0.2381 2.28e-07 7oza:AAA
55 1fsu:A 475 204 0.1174 0.1221 0.2843 1.41e-11
56 1fsu:A 475 96 0.0547 0.0568 0.2812 0.003
57 6hhm:A 459 103 0.0709 0.0763 0.3398 9.11e-11
58 6hhm:A 459 99 0.0607 0.0654 0.3030 1.27e-08
59 7oz9:BBB 483 199 0.1174 0.1201 0.2915 1.35e-10 7oz9:AAA
60 7oz9:BBB 483 201 0.1073 0.1097 0.2637 6.40e-07 7oz9:AAA
61 7aj0:A 501 108 0.0749 0.0739 0.3426 8.35e-07 7aj0:B, 7aj0:C, 7aj0:D, 7aj0:E, 7aj0:F
62 7aj0:A 501 138 0.0810 0.0798 0.2899 0.005 7aj0:B, 7aj0:C, 7aj0:D, 7aj0:E, 7aj0:F
63 6xlp:A 586 96 0.0506 0.0427 0.2604 2.34e-04
64 4uor:A 418 73 0.0445 0.0526 0.3014 0.019 4uoo:A, 4uoo:B, 4uoo:C, 4uoo:D, 4uoo:E, 4uor:B, 4uor:C, 4uor:D, 4uor:E, 4uor:F, 4uor:G, 4uor:H, 4uor:I, 4uor:J, 4uor:K
65 7tl7:A 531 108 0.0607 0.0565 0.2778 0.020 5kgl:A, 5kgl:B, 5kgm:A, 5kgm:B, 5kgn:A, 5kgn:B, 7knf:A, 7knf:B, 7kng:A, 7kng:B, 7tl7:B, 7tl7:C, 7tl7:D
66 6a7w:A 324 80 0.0486 0.0741 0.3000 0.030 6a7w:B, 5mx9:A, 6sut:A
67 1o98:A 509 142 0.0769 0.0747 0.2676 0.035 1ejj:A, 1eqj:A, 1o99:A
68 2w5q:A 424 101 0.0567 0.0660 0.2772 0.092 2w5r:A, 2w5s:A, 2w5t:A
69 6bnf:A 336 167 0.0870 0.1280 0.2575 0.14 6bnc:A, 6bnc:B, 6bnd:A, 6bnd:B
70 5yle:A 331 80 0.0445 0.0665 0.2750 0.32 5gov:B, 5gov:A, 5grr:A, 5k4p:A, 6li4:A, 6li4:B, 6li6:A, 6li6:B, 5lrm:A, 5lrn:A, 5lrn:B, 7yjp:A, 7yjp:B, 7yjq:A, 7yjq:B, 7yjr:A, 7yjr:B, 7yjs:A, 7yjs:B, 7yjt:A, 7yjt:B, 5ylc:A, 5ylf:A, 5zjv:A
71 5tcd:A 388 57 0.0405 0.0515 0.3509 0.35 5udy:A
72 5vpu:A 509 108 0.0587 0.0570 0.2685 0.74
73 4uop:B 409 112 0.0506 0.0611 0.2232 1.2 4uop:A
74 1kmy:A 288 66 0.0445 0.0764 0.3333 2.1 1han:A, 1knd:A, 1knf:A, 1lgt:A, 1lkd:A
75 4lqy:A 379 36 0.0283 0.0369 0.3889 2.3 4lr2:A
76 5jhx:A 735 93 0.0587 0.0395 0.3118 4.1 5cjh:A, 5cjh:B, 5jhx:B, 5jhy:A, 5jhy:B, 5jhz:A, 5jhz:B, 3ut2:A, 3ut2:B
77 6ldo:A 381 45 0.0304 0.0394 0.3333 4.7 6ldo:B, 6ldo:C, 6ldo:D, 6ldo:E, 6ldo:F, 6le4:A, 6le4:B, 6le4:C, 6le4:D, 6le4:E, 6le4:F
78 1lkx:C 679 193 0.0870 0.0633 0.2228 5.0 1lkx:A, 1lkx:B, 1lkx:D
79 8vq3:B 270 52 0.0324 0.0593 0.3077 6.5 8vq4:B
80 4nwj:A 504 107 0.0587 0.0575 0.2710 7.2 4my4:A, 4nwx:A, 4qax:A, 7tl8:A
81 5in4:A 355 69 0.0364 0.0507 0.2609 7.4 6gpj:A, 6gpj:B, 6gpj:D, 6gpj:C, 6gpk:A, 6gpk:B, 6gpk:C, 6gpk:D, 6gpl:B, 6gpl:E, 6gpl:C, 6gpl:D, 5in4:B, 5in4:C, 5in4:D, 5in5:A, 5in5:B, 5in5:C, 5in5:D, 6q94:B, 6q94:A, 6q94:C, 6q94:E, 6q94:D, 6q94:F, 6q94:G, 6q94:H, 1t2a:A, 1t2a:D, 1t2a:B, 1t2a:C
82 1h7a:A 563 47 0.0263 0.0231 0.2766 7.9 1h78:A, 1h79:A, 1h7b:A, 1hk8:A
83 5fgn:A 536 81 0.0445 0.0410 0.2716 8.4 4kav:A, 4kay:A, 4kay:B
84 1a4a:A 129 42 0.0283 0.1085 0.3333 9.0 1a4a:B, 1a4b:A, 1a4b:B, 1a4c:A, 1a4c:B, 1a4c:C, 1a4c:D, 1azb:A, 1azb:B, 1azc:A, 1azc:B, 2aza:A, 2aza:B, 1uri:A, 1uri:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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