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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILRVRYNMAPFSVEE
RKKPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIE
GEIVLDLNKEEDNYGEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYLKIAQE

The query sequence (length=236) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2pnz:A 236 236 1.0000 1.0000 1.0000 1.27e-171 2po0:A, 2po1:A, 2po2:A
2 2c39:D 248 236 0.6186 0.5887 0.6186 1.58e-107 4ba1:B, 4ba2:B, 2c37:B, 2c37:F, 2c37:N, 2c37:V, 2c37:X, 2c38:B, 2c38:F, 2c38:H, 2c38:J, 2c38:N, 2c38:V, 2c38:X, 2c39:B, 2c39:F, 2c39:H, 2c39:J, 2c39:L, 2c39:N, 2c39:P, 2c39:R, 2c39:T, 2c39:V, 2c39:X, 2jea:B
3 2wnr:B 222 219 0.6059 0.6441 0.6530 1.52e-103 2wnr:D, 2wnr:F
4 3m7n:E 248 235 0.5975 0.5685 0.6000 9.04e-102 3m7n:F, 3m7n:D, 3m85:F, 3m85:D, 3m85:E
5 6d6q:B 241 221 0.3856 0.3776 0.4118 1.33e-58 6d6r:B
6 6fsz:BB 244 233 0.3263 0.3156 0.3305 8.56e-31 4ifd:B, 5jea:B, 5k36:B, 8qcf:C
7 1r6m:A 236 241 0.3220 0.3220 0.3154 1.85e-24
8 3dd6:A 244 237 0.3178 0.3074 0.3165 2.67e-22
9 6d6q:F 252 218 0.3178 0.2976 0.3440 5.50e-21 6d6r:F
10 4aim:A 698 201 0.2966 0.1003 0.3483 1.79e-19 4aid:A, 4aid:B, 4aid:C, 4am3:A, 4am3:C, 4am3:B
11 4aim:A 698 183 0.1949 0.0659 0.2514 0.006 4aid:A, 4aid:B, 4aid:C, 4am3:A, 4am3:C, 4am3:B
12 7ogk:A 695 199 0.2797 0.0950 0.3317 1.01e-17 3gcm:A, 3gcm:B, 3gcm:C, 3h1c:A, 3h1c:B, 3h1c:C, 3h1c:K, 3h1c:G, 3h1c:I, 3h1c:M, 3h1c:O, 3h1c:R, 3h1c:T, 3h1c:V, 3h1c:X, 7ogk:B, 7ogk:C, 7ogm:L, 7ogm:N, 7ogm:O
13 5yjj:A 442 232 0.3136 0.1674 0.3190 1.95e-17 5yjj:B, 5yjj:C, 5yjj:D, 5yjj:E, 5yjj:F
14 5yjj:A 442 219 0.1949 0.1041 0.2100 0.006 5yjj:B, 5yjj:C, 5yjj:D, 5yjj:E, 5yjj:F
15 3gme:A 482 195 0.2669 0.1307 0.3231 6.22e-17
16 8wx0:A 597 222 0.2881 0.1139 0.3063 6.55e-16 8wx0:B, 8wx0:C
17 7ld5:A 587 213 0.2754 0.1107 0.3052 6.63e-16 7ld5:B, 7ld5:C
18 1e3p:A 645 205 0.2712 0.0992 0.3122 9.73e-15
19 3m85:I 259 243 0.2331 0.2124 0.2263 1.81e-09 3m7n:I, 3m7n:G, 3m7n:H, 3m85:G, 3m85:H
20 2pnz:B 267 91 0.1144 0.1011 0.2967 2.50e-08
21 4ba2:A 274 207 0.1949 0.1679 0.2222 5.02e-08 2c37:I, 2c37:U, 2c38:G, 2c38:I, 2c38:U, 2c38:W, 2jea:A
22 6d6q:C 265 109 0.1144 0.1019 0.2477 8.63e-04 6d6r:C
23 6d6q:A 287 63 0.0847 0.0697 0.3175 0.11 6d6r:A
24 4oo1:E 255 29 0.0508 0.0471 0.4138 2.5
25 2ybo:A 248 105 0.1441 0.1371 0.3238 3.0 2ybq:A
26 8a8g:A 382 67 0.1059 0.0654 0.3731 3.8 8a8d:A, 8a8d:B
27 6dkt:E 268 62 0.0678 0.0597 0.2581 6.5
28 8th5:I 119 19 0.0424 0.0840 0.5263 7.5

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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