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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KIEVKDSTMIKPSAETPGGSLWLSNLDLLSPANYHTLSVHFYSHDGSDNFFDAAGLKESLSRALVEFYPYAGGNRLEIDC
NNEGLLLVEAECDGALDELGDFAPRPELNLIPKVDYSRGISTYPLMVFQLTRFKCGGVALGVANEHHLSDGVAALHFINT
WAHLSRGAPAPTPLPHFDRSSLSARNPPQPQFSHAEYQPPPTLENPLPHTDIAHSRFKLTRDQLNSLYSTFEVLAGHIWR
SVCIARGLPEGQETKLHIPFDGRGRLQLPPGFFGNAIFFATPIATCGEIESNSLNYAVRRVSDGVSRLDEDYLRSSIDFL
ELQEDISKLAQGAHSFRCPNLWVISWVWLPIYEPDFGWGKAVYMGPWAAPFEGKSYLLPNPEKDGSLFVSITLHKQHMER
FEKLFYE

The query sequence (length=407) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6mk2:A 407 407 1.0000 1.0000 1.0000 0.0
2 5kjw:A 425 426 0.5872 0.5624 0.5610 2.42e-172 5kjw:B
3 5kjt:A 431 432 0.5430 0.5128 0.5116 3.36e-154 5kju:A
4 5fal:A 435 438 0.5086 0.4759 0.4726 3.34e-132 5fan:A, 4kec:A
5 6lpv:A 434 446 0.4054 0.3802 0.3700 4.73e-83
6 8dqo:B 437 438 0.2924 0.2723 0.2717 4.40e-28 8dqo:A, 8dqp:A, 8dqp:B, 8dqq:A, 8dqq:B, 8dqr:A
7 6lpw:B 436 440 0.2678 0.2500 0.2477 1.47e-21
8 8h8i:A 431 372 0.2310 0.2181 0.2527 1.93e-17 8hbt:A
9 2e1t:A 440 401 0.2457 0.2273 0.2494 3.40e-17 2e1t:B
10 6wao:A 431 351 0.2211 0.2088 0.2564 5.87e-13
11 6wao:B 406 342 0.2113 0.2118 0.2515 1.83e-12
12 2xr7:A 452 406 0.2260 0.2035 0.2266 3.29e-10
13 7dex:A 460 406 0.2162 0.1913 0.2167 4.06e-10
14 2zba:A 435 308 0.1843 0.1724 0.2435 2.10e-07 2zba:B, 2zba:C
15 3b2s:A 448 341 0.1794 0.1629 0.2141 1.01e-04 3b30:A, 2rkv:A
16 8j2y:A 327 50 0.0418 0.0520 0.3400 0.13 8j2y:B
17 8wa1:B 998 77 0.0565 0.0230 0.2987 0.22
18 3g3n:A 318 69 0.0541 0.0692 0.3188 1.7 4pm0:A, 4y2b:A, 1zkl:A
19 7k01:0 754 51 0.0516 0.0279 0.4118 1.8 8cen:0, 8ceo:0, 6gym:0, 7k04:0, 7m2u:0, 7ml0:0, 7ml1:0, 7ml2:0, 7ml3:0, 7ml4:0, 7o4i:0, 7o4j:0, 7o4k:0, 7o4l:0, 7o72:0, 7o73:0, 7o75:0, 5oqj:0, 5oqm:0, 7zs9:0, 7zsa:0, 7zsb:0
20 4pw7:E 198 98 0.0565 0.1162 0.2347 3.8 4pw5:A, 4pw5:B, 4pw5:E, 4pw5:F, 4pw6:A, 4pw6:B, 4pw7:A, 4pw7:B, 4pw7:F
21 7trc:K 330 51 0.0369 0.0455 0.2941 6.8 7bgb:K
22 7dsn:A 471 66 0.0418 0.0361 0.2576 6.9 2dh3:A, 6jmq:B
23 7v9a:B 377 59 0.0442 0.0477 0.3051 7.6 8oue:K, 8ouf:K
24 8cuy:A 1016 41 0.0418 0.0167 0.4146 8.2

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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