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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KHYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVVLGKLNNLVKEWISDVSESKNLPPSVVATVGGKI
FTFGSYRLGVHTKGADIDALCVAPRHVERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQT
ISDNLDLRDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFLGGVSWAMLVARTC
QLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVM
VEEFKQGLAVTDEILQGKSDWSKLLEPPNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVN
PQSFPGNYVSMWFLGIIFRDLTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKQLHHYLPAEIL

The query sequence (length=467) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4lt6:A 467 467 1.0000 1.0000 1.0000 0.0 4lt6:B
2 1q78:A 470 470 0.7901 0.7851 0.7851 0.0 1f5a:A, 1q79:A
3 7q72:B 502 397 0.3983 0.3705 0.4685 7.05e-136
4 3c66:A 529 411 0.4026 0.3554 0.4574 4.26e-133 3c66:B, 1fa0:A, 1fa0:B, 2q66:A
5 8opp:A 670 77 0.0493 0.0343 0.2987 0.021
6 2q3o:B 367 116 0.0685 0.0872 0.2759 0.041 2g5w:A, 2g5w:B, 2q3o:A, 1q45:A, 1q45:B
7 5w0n:A 379 83 0.0493 0.0607 0.2771 0.16 5w0m:A, 5w0m:C, 5w0n:B
8 5w0b:A 334 83 0.0493 0.0689 0.2771 0.19
9 8opt:A 783 78 0.0450 0.0268 0.2692 0.26 8ops:A, 5w0m:B, 5w0n:C, 5w0o:A, 5w0o:B
10 5dy2:A 378 55 0.0450 0.0556 0.3818 0.55 5dxx:A, 5dxy:A, 5dy3:A
11 7cgm:A 349 84 0.0493 0.0659 0.2738 0.58 7cgf:A, 7cgg:A, 7cgh:A, 7cgi:A, 7cgj:A, 7cgk:A, 7cgl:A, 6nod:A, 6nod:B, 6nod:C
12 7sn8:I 634 194 0.1006 0.0741 0.2423 0.62
13 6ww7:A 927 65 0.0450 0.0227 0.3231 1.2
14 6qvm:A 658 65 0.0428 0.0304 0.3077 4.1
15 6mtp:H 218 29 0.0257 0.0550 0.4138 4.2 6mtp:A
16 6mxv:B 251 75 0.0471 0.0876 0.2933 4.8
17 5kod:D 566 94 0.0578 0.0477 0.2872 4.9
18 6avh:B 541 49 0.0300 0.0259 0.2857 5.2
19 8etf:C 330 56 0.0471 0.0667 0.3929 5.4 8esg:A, 8esg:H, 8etf:H, 8etf:A, 8etf:B, 8etf:D, 8etf:E, 8etf:F, 8etf:G, 8fao:H, 8fao:A, 8fao:B, 8fao:C, 8fao:D, 8fao:E, 8fao:F, 8fao:G
20 4abt:A 286 38 0.0343 0.0559 0.4211 6.2 4abt:B, 1fiu:A, 1fiu:B, 1fiu:D, 1fiu:C
21 1icp:A 358 62 0.0428 0.0559 0.3226 6.4 3hgr:A, 3hgr:B, 1icp:B, 1icq:A, 1icq:B, 1ics:A, 1ics:B
22 6e1q:A 569 52 0.0321 0.0264 0.2885 9.2 6avh:A, 6avh:C, 6avh:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218