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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HMRFGRIATPDGMCFCSIEGEGDDVANLTAREIEGTPFTEPKFTGREWPLKDVRLLAPMLPSKVVAIGRNYADHVAEVFK
KSAESLPPTLFLKPPTAVTGPESPIRIPSFATKVEFEGELAVVIGKPCKNVKADDWKSVVLGFTIINDVSSRDLQFADGQ
WARAKGIDTFGPIGPWIETDINSIDLDNLPIKARLTHDGETQLKQDSNSNQMIMKMGEIIEFITASMTLLPGDVIATGSP
AGTEAMVDGDYIEIEIPGIGKLGNPVVDA

The query sequence (length=269) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4dbh:A 269 269 1.0000 1.0000 1.0000 0.0 4dbf:A, 4dbf:B, 4dbh:B
2 3qdf:A 252 268 0.5353 0.5714 0.5373 5.01e-92
3 6iym:A 277 223 0.3197 0.3105 0.3857 1.35e-40 6iym:B
4 8sky:B 303 229 0.3048 0.2706 0.3581 7.29e-36 8sky:A, 8sut:A, 8sut:B, 8suu:A, 8suu:B
5 6jvw:B 264 221 0.3011 0.3068 0.3665 1.37e-35 6jvw:A
6 3r6o:A 265 255 0.3086 0.3132 0.3255 2.11e-33
7 6j5x:A 280 219 0.2677 0.2571 0.3288 2.38e-33 6j5x:B
8 8gsr:A 290 214 0.2900 0.2690 0.3645 2.30e-32 8gsr:B, 8gsr:C, 8gsr:D, 8gst:A, 8gst:B, 8gst:C, 8gst:D
9 6v77:B 279 219 0.2788 0.2688 0.3425 4.22e-27 6v77:A
10 6fog:A 218 200 0.2528 0.3119 0.3400 1.04e-26 6fog:C, 6fog:G, 6fog:E, 6fog:F, 6fog:H, 6fog:D, 6fog:B, 6foh:A, 6foh:B, 1saw:A, 1saw:B
11 1nkq:A 247 220 0.2491 0.2713 0.3045 3.36e-24 1nkq:B, 1nkq:C, 1nkq:D, 1nkq:E, 1nkq:F
12 6sbi:A 216 200 0.2305 0.2870 0.3100 1.13e-23 6sbi:B, 6sbi:C, 6sbi:D, 6sbj:A, 6sbj:B, 6sbj:C, 6sbj:D
13 6j5y:A 233 213 0.2305 0.2661 0.2911 6.07e-20
14 1nr9:A 211 201 0.2268 0.2891 0.3035 9.11e-20 1nr9:B, 1nr9:C, 1nr9:D
15 1gtt:A 421 189 0.2379 0.1520 0.3386 7.74e-19 1gtt:B, 1gtt:C, 1gtt:D, 1i7o:A, 1i7o:B, 1i7o:C, 1i7o:D
16 1gtt:A 421 208 0.2268 0.1449 0.2933 2.57e-13 1gtt:B, 1gtt:C, 1gtt:D, 1i7o:A, 1i7o:B, 1i7o:C, 1i7o:D
17 3v77:A 224 199 0.2230 0.2679 0.3015 1.16e-18 3v77:B, 3v77:C, 3v77:D, 3v77:E, 3v77:F
18 3bqb:X 291 242 0.2379 0.2199 0.2645 1.49e-12 3bqb:A, 3bqb:Z, 3bqb:Y, 2q1a:X, 2q1c:X, 2q1d:X
19 3lzk:C 343 184 0.1599 0.1254 0.2337 2.35e-04 3lzk:A, 3lzk:B, 3lzk:D
20 5ti1:H 430 245 0.2119 0.1326 0.2327 0.60 5ti1:A, 5ti1:B, 5ti1:C, 5ti1:D, 5ti1:E, 5ti1:F, 5ti1:G
21 2q42:A 254 96 0.0929 0.0984 0.2604 0.70 2q42:B, 1xm8:A, 1xm8:B
22 3d9v:A 400 53 0.0632 0.0425 0.3208 1.0 5bml:A, 5bml:B, 3d9v:B, 6e9w:A, 6e9w:B, 2esm:A, 2esm:B, 2etk:A, 2etk:B, 2etr:A, 2etr:B, 5hvu:A, 5hvu:B, 7jou:A, 5kks:A, 5kks:B, 5kkt:A, 5kkt:B, 3ncz:A, 3ncz:B, 3ncz:C, 3ncz:D, 3ndm:B, 3ndm:D, 7s25:B, 7s25:C, 7s26:A, 7s26:B, 7s26:C, 3tv7:A, 3tv7:B, 3tv7:C, 3tv7:D, 3twj:A, 3twj:C, 5uzj:A, 5uzj:B, 2v55:A, 2v55:C, 3v8s:A, 3v8s:B, 3v8s:C, 3v8s:D, 4w7p:A, 4w7p:B, 4w7p:C, 4w7p:D, 5wne:A, 5wne:C, 5wne:D, 5wnf:A, 5wnf:C, 5wnf:D, 5wng:A, 5wng:C, 5wng:D, 5wnh:A, 5wnh:C, 5wnh:D, 4yvc:A, 4yvc:B, 4yve:A, 4yve:B
23 7s25:A 373 53 0.0632 0.0456 0.3208 1.1 3ndm:C, 5wnf:B, 5wng:B, 5wnh:B
24 5wne:B 352 39 0.0520 0.0398 0.3590 1.4
25 2x6k:A 550 47 0.0595 0.0291 0.3404 4.4 2x6f:A, 2x6f:B, 2x6i:A, 2x6i:B, 2x6j:A, 2x6j:B, 2x6k:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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