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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HGIRMTRISREMMKELLSVYFIMGSNNTKADPVTVVQKALKGGATLYQFREKGGDALTGEARIKFAEKAQAACREAGVPF
IVNDDVELALNLKADGIHIGQEDANAKEVRAAIGDMILGVSAHTMSEVKQAEEDGADYVGLGPIYPTETKKDTRAVQGVS
LIEAVRRQGISIPIVGIGGITIDNAAPVIQAGADGVSMISAISQAEDPESAARKFREEIQTYKTGR

The query sequence (length=226) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1g69:B 228 226 0.9956 0.9868 0.9956 1.55e-165 1g4p:A, 1g4p:B, 1g4s:A, 1g4s:B, 1g4t:A, 1g4t:B, 1g67:A, 1g67:B, 1g69:A, 1g6c:A, 1g6c:B, 3o15:A, 2tps:A, 2tps:B
2 3nl6:A 518 193 0.2743 0.1197 0.3212 1.04e-21 3nl3:A, 3nl3:B, 3nl3:C, 3nl3:D, 3nl3:E, 3nl3:F, 3nl5:A, 3nl5:B, 3nl5:C, 3nl6:B, 3nl6:C, 3nm1:A, 3nm1:B, 3nm1:C, 3nm1:D, 3nm1:E, 3nm1:F, 3nm3:A, 3nm3:B, 3nm3:C, 3nm3:D, 3nm3:E, 3nm3:F
3 3qh2:B 196 144 0.2080 0.2398 0.3264 2.23e-19 3qh2:A, 3qh2:C, 3qh2:D
4 4wy0:B 260 68 0.1062 0.0923 0.3529 0.012 4wy0:D, 4wy0:E, 4wy0:G, 4wy0:I, 4wy0:J, 4wy0:K, 1znn:A, 1znn:B, 1znn:C, 1znn:D, 1znn:E, 1znn:F
5 1tyg:A 242 60 0.0885 0.0826 0.3333 0.086 1tyg:C
6 8u7j:L 267 55 0.0885 0.0749 0.3636 0.16 8u7j:K, 8u7j:I, 8u9e:B
7 1wa3:D 203 115 0.1372 0.1527 0.2696 0.19 1wa3:A, 1wa3:B, 1wa3:C, 1wa3:E, 1wa3:F
8 1h5y:B 253 90 0.1283 0.1146 0.3222 0.27 1h5y:A
9 8hlk:A 910 49 0.0796 0.0198 0.3673 0.30
10 2iss:B 285 71 0.1018 0.0807 0.3239 0.37 2iss:A, 2iss:C
11 3wg6:A 299 74 0.0841 0.0635 0.2568 1.3 3wg6:B, 3wg6:C, 3wg6:D
12 5ayy:A 289 96 0.1327 0.1038 0.3125 1.8 5ayy:B, 5ayy:C, 5ayy:D, 5ayy:E, 5ayy:F, 5ayy:G, 5ayy:H, 5ayy:I, 5ayz:A, 5ayz:B, 5ayz:C, 5ayz:D, 5ayz:E, 5ayz:F, 5ayz:G, 5ayz:H, 5ayz:I, 5ayz:J, 5ayz:K, 5ayz:L, 4kww:A, 4kww:B, 4kww:C, 4kww:D, 4kww:E, 4kww:F
13 5xxz:B 1310 64 0.0973 0.0168 0.3438 2.5
14 3qc3:A 225 55 0.0796 0.0800 0.3273 2.7 3ovp:A, 3ovp:B, 3ovq:A, 3ovq:B, 3ovr:A, 3ovr:B, 3qc3:B
15 2v55:D 182 45 0.0619 0.0769 0.3111 2.8 1gwn:A, 1gwn:C, 1m7b:A, 2v55:B
16 4ads:A 282 58 0.0796 0.0638 0.3103 2.9 4ads:B, 4ads:C, 4ads:D, 4ads:E, 4ads:F, 4adt:A, 4adt:B, 4adu:A, 4adu:B
17 3ivt:B 400 77 0.0841 0.0475 0.2468 3.2 3ivs:A, 3ivs:B, 3ivt:A, 3ivu:A, 3ivu:B, 3mi3:A, 3mi3:B
18 8hvc:A 602 74 0.0885 0.0332 0.2703 3.3 8hvb:A, 8hvd:A
19 5k2z:B 278 54 0.0841 0.0683 0.3519 3.9 5k2z:A, 5k2z:C, 5k2z:D, 5lnr:A, 5lnr:B, 5lnr:C, 5lnr:D, 5lns:A, 5lns:B, 5lns:C, 5lns:D, 5lnt:A, 5lnt:B, 5lnt:C, 5lnt:D, 5lnu:A, 5lnu:B, 5lnu:C, 5lnu:D, 5lnv:A, 5lnv:B, 5lnv:C, 5lnv:D, 5lnw:A, 5lnw:B, 5lnw:C, 5lnw:D, 7nhe:A, 7nhe:B, 7nhe:C, 7nhe:D
20 3exs:D 218 45 0.0664 0.0688 0.3333 5.0 3exs:A, 3ext:A
21 6ont:A 121 40 0.0442 0.0826 0.2500 5.6
22 4gyj:A 618 39 0.0619 0.0227 0.3590 6.3 3bmx:A, 3bmx:B, 4gyj:B, 4gyk:A, 3nvd:A, 3nvd:B
23 8tc8:A 435 73 0.0841 0.0437 0.2603 6.9 8h53:A, 8h53:B, 8h53:C, 8h53:D, 8tc8:B, 8tc8:C, 8tc8:D, 8tc9:A, 8tc9:B, 8tc9:C, 8tc9:D
24 4ori:A 355 32 0.0619 0.0394 0.4375 8.7 1uum:A, 1uum:B, 1uuo:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218