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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HCGRAAPCEPLRYNVCLGSVLPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRCWAVIQPLLCAVYMPKCENDRVELP
SRTLCQATRGPCAIVERERGWPDFLRCTPDRFPEGCTNEVQNIKFNSSGQCEVPLVRTDNPKSWYEDVEGCGIQCQNPLF
TEAEHQDMHSYIAAFGAVTGLCTLFTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRADGTMR
LGEPTSNETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSFKALGTTYQPLSGKTSYFHLLTWSLPFVLTVAILAVAQVD
GRSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSIKSNHPGLLSEKAASKINETMLRLGIFGFLAFGF
VLITFSCHFYDFFNQAEWERSFRDYVLCQANVDCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWT

The query sequence (length=465) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6o3c:A 484 468 0.9806 0.9421 0.9744 0.0 6ot0:R, 6xbj:R, 6xbk:R, 6xbl:R, 6xbm:R
2 5v57:A 645 375 0.7978 0.5752 0.9893 0.0 1akq:A, 1akr:A, 1akt:A, 1aku:A, 1akv:A, 1akw:A, 1azl:A, 1bu5:A, 1bu5:B, 1c7e:A, 1c7e:B, 1c7f:A, 1c7f:B, 1f4p:A, 1fx1:A, 2fx2:A, 3fx2:A, 4fx2:A, 5fx2:A, 1i1o:A, 1j8q:A, 1j9e:A, 1j9g:A, 5v56:A, 5v56:B, 5v57:B, 1wsb:A, 1wsw:A, 1xt6:A, 1xyv:A, 1xyy:A, 5yob:A, 5yoc:A, 5yoe:A, 5yog:A
3 5v57:A 645 99 0.1828 0.1318 0.8586 4.95e-47 1akq:A, 1akr:A, 1akt:A, 1aku:A, 1akv:A, 1akw:A, 1azl:A, 1bu5:A, 1bu5:B, 1c7e:A, 1c7e:B, 1c7f:A, 1c7f:B, 1f4p:A, 1fx1:A, 2fx2:A, 3fx2:A, 4fx2:A, 5fx2:A, 1i1o:A, 1j8q:A, 1j9e:A, 1j9g:A, 5v56:A, 5v56:B, 5v57:B, 1wsb:A, 1wsw:A, 1xt6:A, 1xyv:A, 1xyy:A, 5yob:A, 5yoc:A, 5yoe:A, 5yog:A
4 7zi0:A 593 368 0.7828 0.6138 0.9891 0.0 256b:A, 256b:B, 5l7d:A, 5l7i:A, 5l7i:B, 4o9r:A, 4qim:A, 4qin:A, 1qpu:A, 7zi0:B
5 7zi0:A 593 96 0.1828 0.1433 0.8854 1.62e-47 256b:A, 256b:B, 5l7d:A, 5l7i:A, 5l7i:B, 4o9r:A, 4qim:A, 4qin:A, 1qpu:A, 7zi0:B
6 4n4w:A 457 338 0.7140 0.7265 0.9822 0.0 4jkv:A, 4jkv:B
7 6d35:A 581 374 0.6387 0.5112 0.7941 0.0 6d32:A, 5kzv:A, 5kzy:A, 5kzy:B, 5kzz:A, 1lm3:B, 1lm3:D, 1qq3:A
8 6d35:A 581 96 0.1699 0.1360 0.8229 6.97e-44 6d32:A, 5kzv:A, 5kzy:A, 5kzy:B, 5kzz:A, 1lm3:B, 1lm3:D, 1qq3:A
9 8cxo:A 551 247 0.5226 0.4410 0.9838 4.97e-176
10 8cxo:A 551 83 0.1763 0.1488 0.9880 1.63e-47
11 8wm9:A 320 324 0.1849 0.2687 0.2654 9.51e-34 8wm9:B
12 6bd4:A 379 371 0.1935 0.2375 0.2426 7.09e-30
13 6tfb:A 128 64 0.0495 0.1797 0.3594 1.34e-05 4f0a:A, 6tfb:B
14 5ury:A 119 110 0.0624 0.2437 0.2636 0.058 5urz:A
15 6z1p:At 183 70 0.0409 0.1038 0.2714 5.0
16 3efo:B 767 77 0.0473 0.0287 0.2857 6.7 3eg9:B, 5kyu:B, 5kyw:B, 5kyx:B, 5kyy:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218