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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GSMADVPANLMEQIHGLETLFTVSSEKMRSIVKHFISELDKGLSKKGGNIPMIPGWVVEYPTGKETGDFLALDLGGTNLR
VVLVKLGGNHDFDTTQNKYRLPDHLRTGTSEQLWSFIAKCLKEFVDEWYPDGVSEPLPLGFTFSYPASQKKINSGVLQRW
TKGFDIEGVEGHDVVPMLQEQIEKLNIPINVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLL
PEDIGPDSPMAINCEYGSFDNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLLDLYDSGFIFKDQDIS
KLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTVVERKLIRKLAELVGTRAARLTVCGVSAICDKRGYKTAHI
AADGSVFNRYPGYKEKAAQALKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIACLTQKRLAAGKSVGIKGE

The query sequence (length=472) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3o5b:A 479 472 1.0000 0.9854 1.0000 0.0 3o5b:B, 3o80:A, 3o8m:A
2 3b8a:X 470 471 0.7055 0.7085 0.7070 0.0
3 6pdt:A 500 476 0.3856 0.3640 0.3824 2.69e-90 6pdt:B, 6pdt:C, 6pdt:D
4 4qs7:A 455 441 0.3475 0.3604 0.3719 1.62e-88 4qs9:A
5 3hm8:A 441 451 0.3284 0.3515 0.3437 1.56e-83 3hm8:B, 3hm8:C, 3hm8:D
6 6jj7:A 465 461 0.3538 0.3591 0.3623 3.84e-83 6jj7:C, 6jj7:E, 6jj8:C, 6jj8:A, 6jj8:B, 6jj9:C, 6jj9:A, 6jj9:E, 5zqt:A, 5zqt:B, 5zqt:C
7 5hg1:A 867 451 0.3326 0.1811 0.3481 1.22e-82
8 5hg1:A 867 447 0.2924 0.1592 0.3087 3.40e-55
9 5hfu:B 897 452 0.3326 0.1750 0.3473 8.83e-82 5hex:A, 5hex:B, 5hfu:A, 2nzt:A
10 5hfu:B 897 450 0.3072 0.1616 0.3222 4.59e-68 5hex:A, 5hex:B, 5hfu:A, 2nzt:A
11 3idh:A 453 461 0.3114 0.3245 0.3189 1.07e-80 3a0i:X, 4dhy:A, 6e0e:A, 6e0i:A, 3f9m:A, 3fgu:A, 3fr0:A, 3goi:A, 3h1v:X, 3id8:A, 3imx:A, 4iwv:A, 4ixc:A, 4l3q:A, 4mle:A, 4mlh:A, 4no7:A, 3qic:A, 4rch:A, 3s41:A, 7t78:A, 7t78:B, 7t79:A, 7t79:B, 1v4s:A, 3vev:A, 3vey:A, 3vf6:A
12 1qha:A 903 468 0.3496 0.1827 0.3526 7.90e-80 1bg3:A, 1bg3:B, 1cza:N, 1dgk:N, 4f9o:A, 4f9o:B, 4foe:A, 4foe:B, 4foi:A, 4foi:B, 4fpa:A, 4fpa:B, 4fpb:A, 4fpb:B, 1hkb:A, 1hkb:B, 1hkc:A, 1qha:B
13 1qha:A 903 453 0.3178 0.1661 0.3311 1.70e-68 1bg3:A, 1bg3:B, 1cza:N, 1dgk:N, 4f9o:A, 4f9o:B, 4foe:A, 4foe:B, 4foi:A, 4foi:B, 4fpa:A, 4fpa:B, 4fpb:A, 4fpb:B, 1hkb:A, 1hkb:B, 1hkc:A, 1qha:B
14 2nzt:B 867 448 0.3263 0.1776 0.3438 1.88e-77
15 2nzt:B 867 446 0.3051 0.1661 0.3229 8.76e-69
16 1bdg:A 444 452 0.3178 0.3378 0.3319 8.02e-77
17 4dch:A 434 462 0.2903 0.3157 0.2965 1.53e-67 4ise:A, 4isf:A, 4isg:A, 5v4w:A, 5v4x:A
18 6ksr:A 467 465 0.3114 0.3148 0.3161 8.35e-55
19 2yhx:A 457 453 0.2754 0.2845 0.2870 2.37e-54
20 7zzi:B 467 484 0.3157 0.3191 0.3079 4.89e-50 7zzi:A
21 4nh4:A 352 210 0.0975 0.1307 0.2190 0.79 4nh4:B, 4we3:A, 4we3:B, 4we3:C, 4we3:D, 4wgg:A, 4wgg:B
22 7ohx:W 122 63 0.0403 0.1557 0.3016 1.2
23 3f63:A 218 62 0.0318 0.0688 0.2419 1.2 3f63:B, 3f6d:A, 3f6d:B, 3g7i:B, 3g7j:A, 3g7j:B
24 3zx2:B 399 76 0.0466 0.0551 0.2895 2.1 3zx0:A, 3zx0:B, 3zx0:C, 3zx0:D, 3zx2:A, 3zx2:C, 3zx2:D
25 6x2f:A 1144 71 0.0445 0.0184 0.2958 2.5 7ssg:A, 6x26:A, 6x2n:A, 6x43:A, 6x4w:A, 6x4y:A, 6x50:A
26 6xeo:A 1118 71 0.0445 0.0188 0.2958 2.6
27 3eo3:A 288 19 0.0275 0.0451 0.6842 2.9 3eo3:B, 3eo3:C
28 8suc:A 282 45 0.0339 0.0567 0.3556 3.1
29 3sfv:A 179 64 0.0360 0.0950 0.2656 3.2 8alk:B, 7eq2:A, 7eq2:B, 4fmb:B, 4fmb:D, 4fmb:F, 4fmc:B, 4fmc:D, 4fmd:B, 4fmd:D, 4fmd:F, 4fme:B, 4fme:E, 2fol:A, 4hlq:B, 4hlq:D, 4hlq:F, 4hlq:H, 4hlq:J, 4i1o:A, 4i1o:C, 4i1o:E, 4i1o:G, 4iru:B, 4iru:D, 4iru:F, 4jvs:B, 3nkv:A, 3nkv:B, 5o74:B, 5o74:D, 5o74:F, 5o74:H, 5o74:J, 5o74:L, 6sku:B, 5szh:B, 5szk:B, 3tkl:A
30 7yyl:E 243 31 0.0254 0.0494 0.3871 3.2 7yyl:F, 7yyl:G, 7yyl:H, 7yzm:G, 7yzm:H, 7yzm:E, 7yzm:F, 7yzq:E, 7yzq:F, 7yzq:G, 7yzq:H
31 2yhw:A 309 19 0.0275 0.0421 0.6842 3.3 2yhy:A, 2yi1:A
32 8in8:C 470 74 0.0466 0.0468 0.2973 4.6 8jl0:B, 8k87:A, 8k87:F, 8k88:A
33 3bu8:B 207 63 0.0360 0.0821 0.2698 5.8 3bu8:A, 3bua:A, 3bua:D, 3bua:B, 3bua:C, 7c5d:A, 7c5d:B, 6j67:A, 4m7c:A, 4m7c:B, 4rqi:A, 4rqi:B, 4rqi:C, 4rqi:D, 5wqd:A, 5wqd:B, 5wqd:C, 5wqd:D, 5wqd:E, 5wqd:F, 5wqd:G
34 3cpj:B 164 43 0.0275 0.0793 0.3023 6.0
35 4ud8:A 500 116 0.0572 0.0540 0.2328 6.2 4ud8:B
36 4q8r:A 241 63 0.0466 0.0913 0.3492 7.0
37 5mji:A 252 47 0.0275 0.0516 0.2766 8.3 5mld:A, 5mld:B, 5mld:C, 5mld:D, 5mld:E, 5mld:F, 5mld:G, 5mld:H

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218