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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVK

The query sequence (length=72) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1zzi:A 82 72 1.0000 0.8780 1.0000 3.38e-46 7cre:A, 1j5k:A, 1zzi:B, 1zzj:A, 1zzj:B
2 2p2r:A 73 61 0.4722 0.4658 0.5574 2.49e-17
3 1ec6:A 87 68 0.3611 0.2989 0.3824 2.39e-10 1ec6:B
4 3vke:A 76 65 0.3750 0.3553 0.4154 4.85e-08 2axy:B, 2axy:D, 2pqu:C, 2pqu:B, 2py9:B, 2py9:C, 3vke:B, 3vke:C, 3vke:D, 1ztg:A, 1ztg:D, 1ztg:B, 1ztg:C
5 2anr:A 155 53 0.3472 0.1613 0.4717 1.98e-07 2ann:A
6 2anr:A 155 62 0.3056 0.1419 0.3548 3.64e-06 2ann:A
7 2axy:A 72 52 0.3194 0.3194 0.4423 1.83e-06 2axy:C, 2pqu:A, 2py9:A
8 8coo:A 191 68 0.3750 0.1414 0.3971 1.21e-05 2n8l:A, 2n8m:A
9 8coo:A 191 68 0.2500 0.0942 0.2647 0.024 2n8l:A, 2n8m:A
10 6y2c:B 84 66 0.3056 0.2619 0.3333 1.22e-05
11 1j4w:A 145 65 0.3333 0.1655 0.3692 3.75e-05 6y2c:A
12 1j4w:A 145 66 0.3056 0.1517 0.3333 5.79e-05 6y2c:A
13 4b8t:A 106 62 0.2222 0.1509 0.2581 0.001
14 3aev:B 177 51 0.2778 0.1130 0.3922 0.25
15 4aim:A 698 41 0.2083 0.0215 0.3659 0.33 4aid:A, 4aid:B, 4aid:C, 4am3:A, 4am3:C, 4am3:B
16 7cdw:A 683 39 0.1806 0.0190 0.3333 0.65 7cdw:B
17 7agb:A 339 66 0.2361 0.0501 0.2576 1.3 7agb:B, 7agb:C, 7agb:D, 7agc:D, 7agc:A, 7agc:B, 7agc:F, 7agd:A, 7agd:B, 7agd:C, 7agd:D, 7age:A, 7age:B, 7age:D, 7age:F, 3fv3:A, 3fv3:B, 3fv3:C, 3fv3:D, 3fv3:E, 3fv3:F, 3fv3:G, 3fv3:H, 3tne:A, 3tne:B
18 8hkx:AS3P 201 63 0.2917 0.1045 0.3333 1.4 8hky:AS3P, 8hkz:AS3P, 8hl1:AS3P, 8hl2:AS3P, 8hl3:AS3P, 8hl4:AS3P, 8hl5:AS3P, 8wkp:AS3P, 8wq2:AS3P, 8wq4:AS3P
19 7z5p:A 505 28 0.1528 0.0218 0.3929 1.4 7z5p:B
20 7lh5:CC 207 29 0.1667 0.0580 0.4138 2.0 5a9z:BG, 5aa0:BG, 4aqy:C, 7azo:S3A, 7azo:S3B, 7azs:S3A, 7azs:S3B, 9b00:1c, 9b00:2c, 4b3m:C, 4b3r:C, 4b3s:C, 4b3t:C, 6b4v:LA, 6b4v:PC, 6boh:MA, 6boh:RC, 6bok:KA, 6bok:NC, 5br8:C, 6buw:QC, 6buw:XC, 6bz6:QC, 6bz6:XC, 6bz7:QC, 6bz7:XC, 6bz8:QC, 6bz8:XC, 6c5l:AC, 6c5l:CC, 6cae:1c, 6cae:2c, 6cao:C, 6cap:C, 6caq:C, 6car:C, 6cas:C, 6cfj:1c, 6cfj:2c, 6cfk:1c, 6cfk:2c, 6cfl:1c, 6cfl:2c, 8cvj:1c, 8cvj:2c, 8cvk:1c, 8cvk:2c, 8cvl:1c, 8cvl:2c, 5czp:XC, 5czp:QC, 6czr:1c, 6czr:2c, 5d8b:DA, 5d8b:ZB, 5dfe:XC, 5dfe:QC, 5dox:1c, 5dox:2c, 5doy:1c, 5doy:2c, 4dr1:C, 4dr2:C, 4dr3:C, 4dr4:C, 4dr5:C, 4dr6:C, 4dr7:C, 6dti:C, 4duy:C, 4duz:C, 7dug:C, 7duh:C, 7dui:C, 7duj:C, 7duk:C, 7dul:C, 4dv0:C, 4dv1:C, 4dv2:C, 4dv3:C, 4dv4:C, 4dv5:C, 4dv6:C, 4dv7:C, 2e5l:C, 5e7k:2E, 5e7k:22, 5e81:2E, 5e81:22, 8ekb:1c, 8ekb:2c, 5el4:2E, 5el4:22, 5el5:2E, 5el5:22, 5el6:2E, 5el6:22, 5el7:2E, 5el7:22, 8ev6:1c, 8ev6:2c, 8ev7:1c, 8ev7:2c, 2f4v:C, 5f8k:1c, 5f8k:2c, 8fc1:1c, 8fc1:2c, 8fc2:1c, 8fc2:2c, 8fc3:1c, 8fc3:2c, 8fc4:1c, 8fc4:2c, 8fc5:1c, 8fc5:2c, 8fc6:1c, 8fc6:2c, 5fdu:1c, 5fdu:2c, 5fdv:1c, 5fdv:2c, 1fjg:C, 6fkr:1c, 6fkr:2c, 8fom:QC, 8fom:XC, 8fon:QC, 8fon:XC, 8g29:1c, 8g29:2c, 8g2a:1c, 8g2a:2c, 8g2b:1c, 8g2b:2c, 8g2c:1c, 8g2c:2c, 8g2d:1c, 8g2d:2c, 4gkj:C, 4gkk:C, 6gsj:2E, 6gsj:22, 6gsk:2E, 6gsk:22, 6gsl:2E, 6gsl:22, 6gzq:C2, 6gzx:C3, 6gzx:C4, 6gzz:C3, 6gzz:C4, 5hau:1c, 5hau:2c, 5hcp:1c, 5hcp:2c, 5hcq:1c, 5hcq:2c, 5hcr:1c, 5hcr:2c, 5hd1:1c, 5hd1:2c, 2hhh:C, 1hnw:C, 1hnx:C, 1hnz:C, 1hr0:C, 1i94:C, 1i95:C, 1i96:C, 1i97:C, 1ibk:C, 1ibl:C, 1ibm:C, 5ib7:2E, 5ib7:22, 5ib8:2E, 5ib8:22, 5ibb:2E, 5ibb:22, 5imq:G, 5imr:G, 5iwa:C, 5j30:QC, 5j30:XC, 5j3c:QC, 5j3c:XC, 5j4b:1c, 5j4b:2c, 5j4c:1c, 5j4c:2c, 5j4d:LA, 5j4d:QC, 1j5e:C, 5j8b:c, 4ji0:C, 4ji1:C, 4ji2:C, 4ji3:C, 4ji4:C, 4ji5:C, 4ji6:C, 4ji7:C, 4ji8:C, 7jql:1c, 7jql:2c, 7jqm:1c, 7jqm:2c, 4jv5:C, 4jya:C, 4k0k:C, 4khp:C, 4kvb:C, 4l47:QC, 4l47:XC, 4l71:QC, 4l71:XC, 4lel:QC, 4lel:XC, 4lf4:C, 4lf5:C, 4lf6:C, 4lf7:C, 4lf8:C, 4lf9:C, 4lfa:C, 4lfb:C, 4lfc:C, 4lfz:QC, 4lfz:XC, 7lh5:AC, 5lmn:C, 5lmo:C, 5lmp:C, 5lmq:C, 5lmr:C, 5lms:C, 5lmt:C, 5lmu:C, 5lmv:C, 4lnt:QC, 4lnt:XC, 4lsk:QC, 4lsk:XC, 4lt8:QC, 4lt8:XC, 7md7:1c, 7md7:2c, 6mkn:C, 6mpf:C, 6mpi:C, 6n1d:AS03, 6n1d:BS03, 1n32:C, 1n33:C, 1n34:C, 1n36:C, 6n9e:1c, 6n9e:2c, 6n9f:1c, 6n9f:2c, 5ndj:2E, 5ndj:22, 5ndk:2E, 5ndk:22, 6nd5:1c, 6nd5:2c, 6nd6:1c, 6nd6:2c, 6ndk:QC, 6ndk:XC, 6nsh:QC, 6nsh:XC, 6nta:QC, 6nta:XC, 6nuo:QC, 6nuo:XC, 6nwy:QC, 6nwy:XC, 4nxm:C, 4nxn:C, 6ny6:C, 6o3m:QC, 6o3m:XC, 6o97:1c, 6o97:2c, 6of1:1c, 6of1:2c, 6of6:QC, 6of6:XC, 6oj2:QC, 6oj2:XC, 6ope:QC, 6ope:XC, 6ord:QC, 6ord:XC, 6osi:QC, 6osi:XC, 3oto:C, 5ot7:B, 6otr:QC, 6otr:XC, 4ox9:C, 6oxa:QC, 6oxa:XC, 6oxi:QC, 6oxi:XC, 4p6f:QC, 4p6f:XC, 4p70:QC, 4p70:XC, 6q95:h, 6qnq:2E, 6qnq:22, 6qnr:2E, 6qnr:22, 7rq8:1c, 7rq8:2c, 7rq9:1c, 7rq9:2c, 7rqa:1c, 7rqa:2c, 7rqb:1c, 7rqb:2c, 7rqc:1c, 7rqc:2c, 7rqd:1c, 7rqd:2c, 7rqe:1c, 7rqe:2c, 3t1h:C, 3t1y:C, 8t8b:1c, 8t8b:2c, 8t8c:1c, 8t8c:2c, 4tua:QC, 4tua:XC, 4tub:QC, 4tub:XC, 4tuc:QC, 4tuc:XC, 4tud:QC, 4tud:XC, 4tue:QC, 4tue:XC, 7u2h:1c, 7u2h:2c, 7u2i:1c, 7u2i:2c, 7u2j:1c, 7u2j:2c, 6ucq:1c, 6ucq:2c, 8ud6:1c, 8ud6:2c, 8ud7:1c, 8ud7:2c, 8ud8:1c, 8ud8:2c, 6uo1:1c, 6uo1:2c, 5uq7:c, 5uq8:c, 2uu9:C, 2uua:C, 2uub:C, 2uuc:C, 8uvr:1c, 8uvr:2c, 8uvs:1c, 8uvs:2c, 2uxb:C, 2uxc:C, 2uxd:C, 7v2l:C, 7v2m:C, 7v2n:C, 7v2o:C, 7v2p:C, 7v2q:C, 4v49:AC, 4v4a:AC, 4v4g:AC, 4v4g:CC, 4v4g:EC, 4v4g:GC, 4v4g:IC, 4v4i:d, 4v4j:d, 4v4p:BF, 4v4r:AC, 4v4s:AC, 4v4t:AC, 4v4x:AF, 4v4y:AF, 4v4z:AF, 4v51:AC, 4v51:CC, 4v5a:AC, 4v5a:CC, 4v5c:AC, 4v5c:CC, 4v5d:AC, 4v5d:CC, 4v5e:AC, 4v5e:CC, 4v5f:AC, 4v5f:CC, 4v5g:AC, 4v5g:CC, 4v5j:AC, 4v5j:CC, 4v5k:AC, 4v5k:CC, 4v5l:AC, 4v5m:AC, 4v5n:AC, 4v5p:AC, 4v5p:CC, 4v5q:AC, 4v5q:CC, 4v5r:AC, 4v5r:CC, 4v5s:AC, 4v5s:CC, 4v63:AC, 4v63:CC, 4v67:AC, 4v67:CC, 4v68:AC, 4v6a:AC, 4v6a:CC, 4v6f:BF, 4v6f:CF, 4v6g:AF, 4v6g:CF, 4v7j:Ac, 4v7j:Bc, 4v7k:Ac, 4v7k:Bc, 4v7l:AC, 4v7l:CC, 4v7m:AC, 4v7m:CC, 4v7p:AC, 4v7p:DC, 4v7w:AC, 4v7w:CC, 4v7x:AC, 4v7x:CC, 4v7y:AC, 4v7y:CC, 4v7z:AC, 4v7z:CC, 4v83:AC, 4v83:CC, 4v84:AC, 4v84:CC, 4v87:BF, 4v87:CF, 4v8a:CC, 4v8a:DC, 4v8b:AF, 4v8b:CF, 4v8c:CF, 4v8c:DF, 4v8d:AF, 4v8d:CF, 4v8e:BF, 4v8e:DF, 4v8f:BF, 4v8f:CF, 4v8g:AC, 4v8g:CC, 4v8h:AC, 4v8h:CC, 4v8i:AC, 4v8i:CC, 4v8j:AC, 4v8j:CC, 4v8n:AC, 4v8n:CC, 4v8o:AC, 4v8q:BC, 4v8u:AC, 4v8u:CC, 4v8x:AC, 4v8x:CC, 5v8i:1c, 5v8i:2c, 4v90:AC, 4v95:AC, 4v95:CC, 4v97:AC, 4v97:CC, 4v9a:AF, 4v9a:CF, 4v9b:AF, 4v9b:CF, 4v9h:AC, 4v9i:AC, 4v9i:CC, 4v9j:AC, 4v9j:CC, 4v9k:AC, 4v9k:CC, 4v9l:AC, 4v9l:CC, 4v9m:AC, 4v9m:CC, 4v9n:AC, 4v9n:CC, 4v9q:BC, 4v9q:DC, 4v9r:AC, 4v9r:CC, 4v9s:AC, 4v9s:CC, 5vp2:1c, 5vp2:2c, 5vpo:QC, 5vpo:XC, 5vpp:QC, 5vpp:XC, 2vqe:C, 2vqf:C, 8vtu:1c, 8vtu:2c, 8vtv:1c, 8vtv:2c, 8vtw:1c, 8vtw:2c, 8vtx:1c, 8vtx:2c, 8vty:1c, 8vty:2c, 1vvj:QC, 1vvj:XC, 1vy4:AC, 1vy4:CC, 1vy5:AC, 1vy5:CC, 1vy6:AC, 1vy6:CC, 1vy7:AC, 1vy7:CC, 4w29:AC, 4w29:CC, 4w2e:c, 4w2f:AC, 4w2f:CC, 4w2g:AC, 4w2g:CC, 4w2h:AC, 4w2h:CC, 4w2i:AC, 4w2i:CC, 4w4g:QC, 4w4g:XC, 5w4k:1c, 5w4k:2c, 5wis:1c, 5wis:2c, 5wit:1c, 5wit:2c, 5wnp:C, 5wnq:C, 5wnr:C, 5wns:C, 5wnt:C, 5wnu:C, 5wnv:C, 4wpo:BC, 4wpo:DC, 4wq1:2E, 4wq1:22, 4wqf:BC, 4wqf:DC, 4wqr:2E, 4wqr:22, 4wqu:BC, 4wqu:DC, 4wqy:BC, 4wqy:DC, 4wr6:2E, 4wr6:22, 4wra:2E, 4wra:22, 4wro:2E, 4wro:22, 4wsd:2E, 4wsd:22, 4wsm:2E, 4wsm:22, 4wt1:2E, 4wt1:22, 4wt8:AC, 4wt8:BC, 4wu1:2E, 4wu1:22, 4wzd:2E, 4wzd:22, 4wzo:2E, 4wzo:22, 4x62:C, 4x64:C, 4x65:C, 4x66:C, 4xej:AS03, 4xej:BS03, 6xhv:1c, 6xhv:2c, 6xhw:1c, 6xhw:2c, 6xhx:1c, 6xhx:2c, 6xhy:1c, 6xhy:2c, 1xmo:C, 1xmq:C, 1xnq:C, 1xnr:C, 6xqd:1c, 6xqd:2c, 6xqe:1c, 6xqe:2c, 4y4o:1c, 4y4o:2c, 4y4p:1c, 4y4p:2c, 4yhh:C, 4ypb:QC, 4ypb:XC, 4yy3:C, 4yzv:QC, 4yzv:XC, 4z3s:1c, 4z3s:2c, 4z8c:1c, 4z8c:2c, 4zer:1c, 4zer:2c, 5zlu:I, 2zm6:C, 4zsn:QC, 4zsn:XC
21 8ul7:A 363 23 0.1389 0.0275 0.4348 2.8 8ule:A, 8um0:A
22 7ogk:A 695 34 0.1667 0.0173 0.3529 2.9 3gcm:A, 3gcm:B, 3gcm:C, 3h1c:A, 3h1c:B, 3h1c:C, 3h1c:K, 3h1c:G, 3h1c:I, 3h1c:M, 3h1c:O, 3h1c:R, 3h1c:T, 3h1c:V, 3h1c:X, 7ogk:B, 7ogk:C, 7ogm:L, 7ogm:N, 7ogm:O
23 4bjh:A 422 25 0.1389 0.0237 0.4000 3.4 3d6n:A
24 7yey:A 162 53 0.2083 0.0926 0.2830 3.5 7vkl:A
25 6tmf:C 193 26 0.1389 0.0518 0.3846 5.3
26 4jvy:A 191 42 0.1667 0.0628 0.2857 5.5 4jvy:B, 2mjh:A
27 1b0n:A 103 15 0.1389 0.0971 0.6667 7.4 3zkc:A, 3zkc:B
28 7jil:h 206 25 0.1667 0.0583 0.4800 8.0
29 1avp:A 204 43 0.1667 0.0588 0.2791 8.3 5fgy:A, 1nln:A, 4pid:A, 4pie:A
30 5hau:1z 730 28 0.1528 0.0151 0.3929 9.7 2bm0:A, 2bm1:A, 1fnm:A, 6gzq:H1, 6gzx:H1, 6gzx:H2, 6gzz:H1, 6gzz:H2, 5hau:2z, 4m1k:A, 4myt:A, 4myu:A, 2om7:L, 5ot7:U, 6q95:G, 6ucq:1v, 6ucq:2v, 4v5f:AY, 4v5f:CY, 4v5m:AY, 4v5n:AY, 4v6t:AY, 4v8u:AY, 4v8u:CY, 4v90:AY, 4v9j:AY, 4v9j:CY, 4v9k:AY, 4v9k:CY, 4v9l:AY, 4v9l:CY, 4v9m:AY, 4v9m:CY, 4w29:AY, 4w29:CY, 4wpo:BZ, 4wpo:DZ, 4wqf:BZ, 4wqf:DZ, 4wqu:BZ, 4wqu:DZ, 4wqy:BZ, 4wqy:DZ

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218