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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GDNEWHKLVIPKGSDWQIDLKAEGKLIVKVNSGIVEIFGTELAVDDEYTFQNWKFPIYAVEETELLWKCPDLTTNTITVK
PNHTMKYIYNLHFMLEKIRMSNFEGPRVVIVGGSQTRKTSLSRTLCSYALKFNAYQPLYINLDPQQPIFTVPGCISATPI
SDILDAQLPTWGQSLTSGATLLHNKQPMVKNFGLERINENKDLYLECISQLGQVVGQRLHLDPQVRRSGCIVDTPSISQL
DENLAELHHIIEKLNVNIMLVLCSETDPLWEKVKKTFGPELGNNNIFFIPKLVDDVYKRSLQRTSIREYFYGSLDTALSP
YAIGVDYEDLTIWKPSNVFDNEVGRVELFPVTITPSNLQHAIIAITFAERRADQATVIKSPILGFALITEVNEKRRKLRV
LLPVPGRLPSKAMILTSYRYLE

The query sequence (length=422) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4c0b:B 430 427 0.9976 0.9791 0.9859 0.0 4c0b:A, 4c0h:A, 2npi:A, 2npi:B, 4oi4:A, 4oi4:C
2 4ohw:A 399 436 0.2417 0.2556 0.2339 8.79e-31 4ohv:A, 4ohx:A, 4ohy:A, 4ohz:A, 4oi0:A, 4oi1:A, 4oi2:A
3 2ood:A 463 57 0.0427 0.0389 0.3158 0.94
4 4v9f:J 144 42 0.0308 0.0903 0.3095 2.2 3cc2:J, 3cc4:J, 3cc7:J, 3cce:J, 3ccj:J, 3ccl:J, 3ccm:J, 3ccq:J, 3ccr:J, 3ccs:J, 3ccu:J, 3ccv:J, 3cd6:J, 3cma:J, 3cme:J, 3cpw:I, 3cxc:I, 1ffk:G, 3g4s:J, 3g6e:J, 3g71:J, 3i55:J, 3i56:J, 1jj2:I, 1k73:K, 1k8a:K, 1k9m:K, 1kc8:K, 1kd1:K, 1kqs:I, 1m1k:K, 1m90:K, 1n8r:K, 1nji:K, 2otj:J, 2otl:J, 3ow2:I, 1q7y:K, 1q81:K, 1q82:K, 1q86:K, 2qa4:J, 2qex:J, 1qvf:I, 1qvg:I, 1s72:J, 4v4p:AM, 4v4r:BN, 4v4s:BN, 4v4t:BN, 1vq4:J, 1vq5:J, 1vq6:J, 1vq7:J, 1vq8:J, 1vq9:J, 1vqk:J, 1vql:J, 1vqm:J, 1vqn:J, 1vqo:J, 1vqp:J, 1w2b:I, 1yhq:J, 1yi2:J, 1yij:J, 1yit:J, 1yj9:J, 1yjn:J, 1yjw:J
5 6of2:B 528 60 0.0427 0.0341 0.3000 2.6 6of2:E, 6of3:B, 6of3:E
6 7pvi:AAA 199 102 0.0545 0.1156 0.2255 3.4 7pvi:BBB, 7pwb:AAA, 7pwb:BBB
7 9bts:a 154 97 0.0640 0.1753 0.2784 3.4 9bts:b, 9bts:c, 9bts:d, 9bts:e, 9bts:f, 9bts:g, 9bts:h
8 6fat:A 508 88 0.0616 0.0512 0.2955 4.5 8bhh:B, 8bhh:A, 6fat:B
9 3d1k:B 146 74 0.0474 0.1370 0.2703 4.8 4g51:B, 4g51:D, 3gkv:B, 3gqg:B, 3gqg:D, 2h8d:B, 2h8d:D, 2h8f:B, 2h8f:D, 1hbh:B, 1hbh:D, 4iro:B, 4iro:D, 1la6:B, 5lfg:B, 5lfg:D, 3nfe:B, 3nfe:D, 3ng6:B, 3ng6:D, 4odc:B, 1pbx:B, 2peg:B, 1s5x:B, 1s5y:B, 1s5y:D, 1t1n:B
10 5xhu:A 329 27 0.0332 0.0426 0.5185 4.8
11 3khu:B 467 37 0.0261 0.0236 0.2973 7.0 6c4j:A, 6c4j:B, 6c4j:C, 6c4j:D, 6c4j:E, 6c4j:F, 6c4j:G, 6c4j:H, 6c4j:I, 6c4j:J, 6c4j:K, 6c4j:L, 6c58:A, 6c58:B, 6c58:C, 6c58:D, 6c58:E, 6c58:F, 6c5a:A, 6c5a:B, 6c5a:C, 6c5a:D, 6c5a:E, 6c5a:F, 6c5z:A, 6c5z:B, 6c5z:C, 6c5z:D, 6c5z:E, 6c5z:F, 3khu:A, 3khu:C, 3khu:D, 3khu:E, 3khu:F, 3prj:A, 3prj:B, 3prj:C, 3prj:D, 3prj:E, 3prj:F, 3ptz:A, 3ptz:B, 3ptz:C, 3ptz:D, 3ptz:E, 3ptz:F, 2q3e:A, 2q3e:B, 2q3e:C, 2q3e:D, 2q3e:E, 2q3e:F, 2q3e:G, 2q3e:H, 2q3e:I, 2q3e:J, 2q3e:K, 2q3e:L, 2qg4:A, 2qg4:B, 2qg4:C, 2qg4:D, 2qg4:E, 2qg4:F, 2qg4:G, 2qg4:H, 3tdk:A, 3tdk:B, 3tdk:G, 3tdk:H, 3tdk:L, 3tdk:K, 3tdk:F, 3tdk:E, 3tdk:D, 3tdk:C, 3tdk:J, 3tdk:I, 5tjh:A, 5tjh:B, 5tjh:C, 5tjh:D, 5tjh:E, 5tjh:F, 5vr8:A, 5vr8:B, 5vr8:C, 5vr8:D, 5vr8:E, 5vr8:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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