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●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
>protein
ESINSRLQLVMKSGKYVLGYKQTLKMIRQGKAKLVILANNCPALRKSEIEYYAMLAKTGVHHYSGNNIELGTACKYYRVC
TLAIIDPGDSDIIR

The query sequence (length=94) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length 		Aligned
length 		Identity
(normalized by query) 		Identity
(normalized by hit) 		Identity (normalized
by aligned length) 		E-value Homologs
to hit
1 4v5z:B6 113 95 1.0000 0.8319 0.9895 1.13e-64 7a01:13, 8a3d:W, 5aj0:Ac, 8b5l:c, 8b6c:c, 9bdl:AL30, 9bdn:AL30, 9bdp:AL30, 7bhp:Lc, 8bhf:P1, 8bpo:b2, 8btk:Bc, 7cpu:Lc, 7cpv:Lc, 4d5y:c, 4d67:c, 6d90:c, 6d9j:c, 9f1b:Bc, 9f1c:Bc, 9f1d:Bc, 7f5s:Lc, 8fky:LO, 8fkz:LO, 8fl2:LO, 8fl3:LO, 8fl4:LO, 8fl6:LO, 8fl7:LO, 8fl9:LO, 8fla:LO, 8flb:LO, 8flc:LO, 8fld:LO, 8fle:LO, 8flf:LO, 6frk:c, 6ftg:c, 6fti:c, 6ftj:c, 8g5y:Lc, 8g5z:Lc, 8g60:Lc, 8g61:Lc, 8g6j:Lc, 8glp:Lc, 6gz3:Ac, 6gz4:Ac, 6gz5:Ac, 6hcf:c3, 6hcj:c3, 6hcm:c3, 6hcq:c3, 8idt:E, 8idy:E, 8ie3:E, 8ifd:2W, 8ife:2W, 8ine:E, 8inf:E, 8ink:E, 6ip5:2W, 6ip6:2W, 6ip8:2W, 8ipd:E, 8ipx:E, 8ipy:E, 8ir1:E, 8ir3:E, 3j7o:c, 3j7p:c, 3j7q:c, 3j7r:c, 3j92:c, 3jag:c, 3jah:c, 3jai:c, 3jaj:c, 3jan:c, 8jdj:h, 8jdk:h, 8jdl:h, 8jdm:h, 8k2c:Lc, 5lks:Lc, 6lqm:E, 6lsr:E, 6lss:E, 7ls1:W2, 7ls2:W2, 6lu8:E, 5lzs:c, 5lzt:c, 5lzu:c, 5lzv:c, 5lzw:c, 5lzx:c, 5lzy:c, 5lzz:c, 7mdz:c, 6mtb:c, 6mtc:c, 6mtd:c, 6mte:c, 7nfx:c, 7nwg:c3, 7nwh:c, 7nwi:c, 7o7y:Bc, 7o7z:Bc, 7o80:Bc, 7o81:Bc, 7obr:c, 8ohd:Lc, 8oj0:Lc, 8oj5:Lc, 8oj8:Lc, 6ole:d, 6olf:d, 6olg:Ac, 6oli:d, 6olz:Ac, 6om0:d, 6om7:d, 7ow7:W, 7oya:c1, 7oyb:c1, 7oyc:c1, 7oyd:c, 8p2k:Bc, 6p5i:Ac, 6p5j:Ac, 6p5k:Ac, 6p5n:Ac, 8q7z:Bc, 8q87:Bc, 8qfd:c, 7qgg:d, 8qoi:Lc, 7qvp:Lc, 7qvp:Mc, 7qwq:c, 7qwr:c, 7qws:c, 6qzp:Lc, 6r5q:c, 6r6g:c, 6r6p:c, 6r7q:c, 8rjb:c, 8rjc:c, 8rjd:c, 8scb:c, 6sgc:c2, 6swa:a, 5t2c:W, 6t59:c3, 7tm3:c, 7toq:AL30, 7tor:AL30, 7tut:c, 7ucj:c, 7uck:c, 4ug0:Lc, 4ujc:Bc, 4ujd:Ac, 4uje:Cc, 4v6x:Cc, 6w6l:d, 6xa1:Lc, 7xnx:Lc, 7xny:Lc, 8xsx:Lc, 8xsy:Lc, 8xsz:Lc, 6y0g:Lc, 8y0w:Lc, 8y0x:Lc, 6y2l:Lc, 6y57:Lc, 6y6x:Lc, 8yoo:Lc, 8yop:Lc, 6z6l:Lc, 6z6m:Lc, 6z6n:Lc, 7zjw:Lf, 7zjx:Lf, 6zm7:Lc, 6zme:Lc, 6zmi:Lc, 6zmo:Lc, 6zvk:13
2 4v6w:Cc 100 95 0.8298 0.7800 0.8211 3.73e-53 6xu6:Cc, 6xu7:Cc, 6xu8:Cc
3 9bh5:Cc 96 94 0.7872 0.7708 0.7872 1.29e-50 9cai:Cc
4 8azw:P 97 94 0.7234 0.7010 0.7234 1.95e-47 8b2l:P3, 7qiw:e, 7qiz:e
5 6zj3:Ls 97 95 0.7234 0.7010 0.7158 3.40e-47
6 8etc:c 97 94 0.6915 0.6701 0.6915 3.20e-44 8esq:c, 8esr:c, 8eug:c, 8eui:c
7 4v3p:Lf 112 89 0.6809 0.5714 0.7191 6.13e-43 8ip8:RA, 8ipa:RA, 8ipb:RA, 8jiv:Cc, 4v7e:Cc, 1ysh:C
8 4v8m:Bg 96 93 0.6170 0.6042 0.6237 6.13e-43 8ova:Bg, 8ove:Bg
9 8rxh:Ld 97 93 0.6064 0.5876 0.6129 1.35e-42 8a3w:d, 8a98:d, 6az3:d, 8ovj:d, 8rxx:Ld, 5t2a:e
10 5xxb:b 96 95 0.7234 0.7083 0.7158 3.36e-42
11 8i9x:Lc 98 94 0.6489 0.6224 0.6489 2.25e-41 8i9y:Lc, 8i9z:Lc, 8ia0:Lc, 7olc:Lc, 7old:Lc, 8oo0:Lc, 8pv1:Lc, 8pv2:Lc, 8pv3:Lc, 8pv4:Lc, 8pv5:Lc, 8pv6:Lc, 8pv7:Lc, 8pv8:Lc, 8pvk:Lc, 8pvl:Lc, 7r81:e1, 7z3n:Lc, 7z3o:Lc
12 4v8p:AG 96 95 0.6277 0.6146 0.6211 4.09e-41 4v8p:DG, 4v8p:FG, 4v8p:HG
13 4v6i:Bf 105 94 0.6170 0.5524 0.6170 8.55e-38 8aaf:P, 8agt:P, 8agu:P, 8agv:P, 8agw:P, 8agx:P, 8agz:P, 5apn:c, 5apo:c, 7b7d:LY, 8bip:Lc, 8bjq:Lc, 8bn3:O0, 8bqd:AY, 8bqx:AY, 7bt6:c, 7btb:c, 6cb1:c, 8ccs:O, 8cdl:O, 8cdr:O, 8ceh:O, 8cf5:O, 8cg8:O, 8cgn:O, 8civ:O, 8cku:O, 8cmj:O, 5dat:O0, 5dat:o0, 5dc3:O0, 5dc3:o0, 5dge:O0, 5dge:o0, 5dgf:O0, 5dgf:o0, 5dgv:O0, 5dgv:o0, 6elz:c, 6em5:c, 8eub:Ac, 8evp:Ac, 8evq:Ac, 8evr:Ac, 8evs:Ac, 8evt:Ac, 8ewb:Ac, 8ewc:Ac, 5fci:O0, 5fci:o0, 5fcj:O0, 5fcj:o0, 6ft6:c, 5gak:e, 6gq1:c, 6gqb:c, 6gqv:c, 5h4p:c, 6hd7:e, 8hfr:cC, 6hhq:AD, 6hhq:DE, 5i4l:O0, 5i4l:o0, 6i7o:AY, 6i7o:XY, 5it7:cc, 3j6x:70, 3j6y:70, 3j77:80, 3j78:80, 3jct:c, 5jcs:c, 5juo:HA, 5jup:HA, 5jus:HA, 5jut:HA, 5juu:HA, 8k2d:Lc, 8k82:Lc, 5lyb:O0, 5lyb:o0, 5m1j:c5, 6m62:c, 5mc6:AY, 5mei:AD, 5mei:DE, 7mpi:Ac, 7mpj:Ac, 6n8j:c, 6n8k:c, 6n8l:c, 6n8m:p, 6n8n:p, 6n8o:p, 7n8b:Ac, 7nac:c, 7nad:c, 5ndg:O0, 5ndg:o0, 5ndv:O0, 5ndv:o0, 5ndw:O0, 5ndw:o0, 7nrc:Le, 7nrd:Le, 5obm:O0, 5obm:o0, 7of1:c, 7oh3:c, 7ohq:c, 7ohr:c, 6oig:c, 5on6:AD, 5on6:DE, 7osa:eL30, 7osm:eL30, 8p8m:RC, 8p8n:RC, 8p8u:RC, 8pfr:RC, 6q8y:AY, 6qik:c, 6qt0:c, 6qtz:c, 7r72:c, 7r7a:c, 6r84:e, 6r86:e, 6r87:e, 6ri5:c, 7rr5:Lc, 6rzz:c, 6s05:c, 6s47:Ae, 6snt:an, 6sv4:AY, 6sv4:XY, 6sv4:zY, 1t0k:B, 6t4q:Lc, 5t62:p, 5t6r:p, 6t7i:Lc, 6t7t:Lc, 6t83:cy, 6t83:N, 5tbw:AD, 5tbw:DE, 6tb3:AY, 5tga:O0, 5tga:o0, 5tgm:O0, 5tgm:o0, 6tnu:AY, 7too:AL30, 7top:AL30, 7u0h:c, 4u3m:O0, 4u3m:o0, 4u3n:O0, 4u3n:o0, 4u3u:O0, 4u3u:o0, 4u4n:O0, 4u4n:o0, 4u4o:O0, 4u4o:o0, 4u4q:O0, 4u4q:o0, 4u4r:O0, 4u4r:o0, 4u4u:O0, 4u4u:o0, 4u4y:O0, 4u4y:o0, 4u4z:O0, 4u4z:o0, 4u50:O0, 4u50:o0, 4u51:O0, 4u51:o0, 4u52:O0, 4u52:o0, 4u53:O0, 4u53:o0, 4u55:O0, 4u55:o0, 4u56:O0, 4u56:o0, 4u6f:O0, 4u6f:o0, 7ug6:7, 7uoo:c, 7uqb:c, 7uqz:c, 6uz7:Bc, 7v08:c, 4v7h:B2, 4v7r:BZ, 4v7r:DZ, 4v88:Bc, 4v88:Dc, 4v8t:c, 4v8y:Bc, 4v8z:Bc, 8v87:c, 4v91:c, 6woo:c, 6xiq:c, 6xir:c, 8y0u:Lc, 6ylg:n, 6ylh:n, 6ylx:c, 6yly:c, 7z34:c, 6z6j:Lc, 6z6k:Lc, 7zpq:Bb, 7zrs:Bb, 7zs5:Bd, 7zuw:Bb, 7zux:Eb, 7zw0:Lf
14 8c3a:AD 96 93 0.6277 0.6146 0.6344 1.22e-37 8c3a:BX, 8cq7:AD, 8cq7:BX, 8cqw:AD, 8cqw:BX, 8cre:AD, 8cre:BX, 8oeq:AD, 8oeq:BX, 7pzy:AD, 7q08:AD, 7q0f:AD, 7q0p:AD, 7q0r:AD, 8q5i:AD
15 3j79:6 98 95 0.6064 0.5816 0.6000 8.37e-37 3jbn:A6, 3jbo:A6, 3jbp:A6, 8tpu:A6, 5umd:6
16 3jcs:d 75 87 0.4468 0.5600 0.4828 2.18e-28
17 5t5h:g 66 59 0.4149 0.5909 0.6610 2.77e-26
18 8br8:Ld 107 93 0.4574 0.4019 0.4624 8.54e-25 8brm:Ld, 8bsi:Ld, 8bsj:Ld, 8btd:Ld, 8btr:Ld, 8fru:c, 7pwg:c, 7pwo:c2
19 5xy3:c 96 94 0.4787 0.4688 0.4787 3.06e-23
20 4v4n:AZ 99 89 0.4043 0.3838 0.4270 1.93e-20 4v6u:BZ
21 8p5d:LCC 99 95 0.3723 0.3535 0.3684 3.50e-18 8p60:LCC, 8p60:KCC, 7qca:LCC
22 6skf:Bb 96 89 0.3723 0.3646 0.3933 6.52e-16 6skg:Bb, 6th6:Bb
23 6zu5:LCC 100 95 0.3404 0.3200 0.3368 1.01e-15
24 7qep:O0 90 90 0.3298 0.3444 0.3444 5.24e-14
25 6rm3:LCC 104 93 0.3085 0.2788 0.3118 1.85e-13
26 8hku:L30E 94 93 0.3085 0.3085 0.3118 1.91e-13 8hkv:L30E, 8hky:L30E, 8hkz:L30E, 8hl1:L30E, 8hl2:L30E, 8hl3:L30E, 8hl4:L30E, 8hl5:L30E
27 5gin:C 122 83 0.2766 0.2131 0.3133 0.005 5gin:D, 5gin:L, 5gio:C, 5gio:D, 5gio:L, 5gip:C, 5gip:D, 5gip:M, 5gip:N, 3id5:C, 3id5:G, 5jpq:U, 5jpq:V, 3pla:C, 3pla:D, 3pla:L
28 8hku:L7A1 123 82 0.2553 0.1951 0.2927 0.018 8hku:L7A2, 8hkv:L7A1, 8hkv:L7A2, 8hkx:SL7A, 8hky:L7A1, 8hky:L7A2, 8hky:SL7A, 8hkz:L7A1, 8hkz:L7A2, 8hkz:SL7A, 8hl1:SL7A, 8hl1:L7A1, 8hl1:L7A2, 8hl2:L7A1, 8hl2:L7A2, 8hl2:SL7A, 8hl3:L7A1, 8hl3:L7A2, 8hl3:SL7A, 8hl4:L7A1, 8hl4:L7A2, 8hl4:SL7A, 8hl5:L7A1, 8hl5:L7A2, 8hl5:SL7A, 8wkp:SL7A, 8wq2:SL7A, 8wq4:SL7A
29 6tmf:b 123 93 0.2553 0.1951 0.2581 0.021
30 5xyi:M 103 40 0.1702 0.1553 0.4000 0.043
31 5y7m:A 125 95 0.2766 0.2080 0.2737 0.078 4by9:G, 4by9:J, 4by9:D, 4by9:M, 5dcv:A, 5dcv:C, 3hax:D, 3hay:D, 3hjw:C, 2hvy:D, 5jb3:3, 5jbh:3, 3lwo:C, 3lwp:C, 3lwq:C, 3lwr:C, 3lwv:C, 3nmu:G, 3nmu:C, 3nvi:B, 3nvi:D, 3nvk:E, 3nvk:H, 7ozq:B, 7ozq:D, 7ozq:C, 7ozq:A, 6skf:BH, 6skf:BI, 6skg:BH, 6skg:BI, 6sw9:3, 6swc:3, 6swe:3, 6th6:BH, 6th6:BI, 6tph:A, 4v4n:B3, 4v4n:AG, 4v6u:A3, 4v6u:BG, 4v6u:B4, 5xtm:A, 5xtm:C, 5y7m:C, 7zag:3, 7zah:3, 7zai:3, 7zhg:3
32 6q8u:C 122 36 0.1596 0.1230 0.4167 0.67 4bw0:B, 4c4w:C, 4c4w:G, 5fj4:C, 5fj4:G, 5g4u:C, 5g4u:D, 5g4u:G, 5g4u:H, 5g4u:K, 5g4u:L, 5g4v:C, 5g4v:D, 5g4v:G, 5g4v:H, 6hct:C, 6hct:D, 6hct:G, 6q8u:D, 1rlg:A, 1rlg:B
33 4gc1:A 275 44 0.1277 0.0436 0.2727 0.94 4gc1:B, 4gc2:B, 3m7j:A, 3m7j:B
34 4lck:A 81 65 0.1809 0.2099 0.2615 0.97 4lck:D, 4tzp:A, 4tzp:D, 4tzv:A, 4tzw:A, 4tzz:A, 4tzz:D, 4tzz:G, 4tzz:J, 3v7e:A, 3v7e:B
35 4d61:h 436 38 0.1170 0.0252 0.2895 0.98 5a8l:Q, 6d90:jj, 6hcf:j1, 6hcm:j1, 6ip8:zw, 3j5y:A, 3jag:ii, 3jah:ii, 3jai:ii, 5lzt:ii, 5lzu:ii, 5lzv:ii, 7nwh:ii, 7o80:By, 6p5n:Aq, 8scb:ii, 6zme:CH
36 3e1y:A 380 38 0.1170 0.0289 0.2895 1.1 3e1y:B, 6xa1:j
37 8fvy:M 103 33 0.1064 0.0971 0.3030 1.3 8g4s:M
38 6et3:A 309 27 0.1170 0.0356 0.4074 2.0
39 5b47:B 275 45 0.1383 0.0473 0.2889 3.5
40 6sxy:B 340 32 0.1383 0.0382 0.4062 3.5 8pc7:A, 8pc7:B, 8pc7:C, 8pc7:D, 6sxy:A, 6sya:A, 6sya:B, 6syl:A, 6syl:B
41 4iee:A 452 49 0.1596 0.0332 0.3061 4.6 5c12:A, 5c15:A, 5c2d:A, 5c2f:A, 4iei:A, 4ife:A
42 6bwh:A 207 57 0.1489 0.0676 0.2456 4.6 6bwh:B, 6bwh:C
43 4o6o:D 199 65 0.2340 0.1106 0.3385 4.9 4o6o:A, 4o6o:B, 4o6o:C, 4o6p:B, 4o6p:C, 3vdp:A, 3vdp:B, 3vdp:C, 3vdp:D, 3vdu:A, 3ve5:D, 3ve5:A
44 3whi:A 355 22 0.1064 0.0282 0.4545 5.8 4dww:A, 5gl8:B, 1mee:A, 6o44:A, 6o44:B, 6pak:A, 6pak:B, 1scj:A, 3vyv:A, 3vyv:B, 3whi:B
45 5b46:B 301 44 0.1383 0.0432 0.2955 8.1
46 8fkt:NB 387 41 0.1383 0.0336 0.3171 8.6 8fkp:NB, 8fku:NB, 8fkv:NB, 8fkw:NB, 8fkx:NB, 8fky:NB, 8fkz:NB, 8fl0:NB, 8ink:u, 8ipd:u, 8ipx:u, 8ipy:u
47 8ip8:bl 437 33 0.1064 0.0229 0.3030 8.6 8ipa:bl
48 2hzp:A 447 74 0.1702 0.0358 0.2162 9.5 3e9k:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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