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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DRFELVKYQPQGDQPKAIEKLVKGIQEGKKHQTLLGATGTGKTFTVSNLIKEVNKPTLVIAHNKTLAGQLYSEFKEFFPN
NAVEYFVSYYDYYQPEAYVPQTDTFIEKDASINDEIDKLRHSATSALFERRDVIIIASVSCIYGLGSPEEYREMVVSLRT
EMEIERNELLRKLVDIQYARNDIDFQRGTFRVRGDVVEIFPASRDEHCVRVEFFGDEIERIREVDALTGEILGDRDHVAI
FPASHFVTRAEKMEKAIQNIEKELEEQLKVMHENGKLLEAQRLEQRTRYDLEMMREMGFCSGIENYSRHLTLRPPGSTPY
TLLDYFPDDFMIVVDESHVTIPQVRGMFNGDQARKQVLVDHGFRLPSALDNRPLRFEEFEKHMHNIVYVSATPGPYEIEH
TDEMVEQIIRPTGLLDPLIDVRPIEGQIDDLIGEIQARIERNERVLVTTLTKKMSEDLTDYLKEIGIKVNYLHSEIKTLE
RIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNAEGRVIMYADKITKSMEIA
INETKRRREQQERFNEEHGITPKTINKKERQKVVEQMEHEMKEAAKALDFERAAELRDLL

The query sequence (length=620) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2d7d:A 621 621 1.0000 0.9984 0.9984 0.0 2nmv:A, 3v4r:B, 3v4r:A
2 6o8e:A 592 590 0.8048 0.8429 0.8458 0.0 1d9z:A, 2fdc:B, 6o8e:B, 6o8f:A, 6o8f:B, 6o8g:A
3 6o8h:A 571 590 0.7694 0.8354 0.8085 0.0 6o8g:B, 6o8g:C
4 2fdc:A 505 356 0.4694 0.5762 0.8174 0.0
5 2fdc:A 505 242 0.2500 0.3069 0.6405 2.96e-92
6 6acx:A 1175 169 0.0790 0.0417 0.2899 1.41e-10 6acx:B
7 5elx:A 391 96 0.0548 0.0870 0.3542 3.94e-07 3peu:A, 3pev:A, 3pew:A, 3pey:A, 3rrm:A, 3rrn:A
8 4bru:A 375 170 0.0694 0.1147 0.2529 2.77e-06
9 7jl0:A 662 125 0.0565 0.0529 0.2800 8.57e-06 7jl2:A, 7jl2:C, 7jl2:E
10 3ex7:C 392 91 0.0484 0.0765 0.3297 1.25e-05 8c6j:7, 3ex7:H, 9fmd:7, 2hyi:C, 2hyi:I, 8i0w:u, 6icz:u, 2j0q:A, 2j0q:B, 2j0s:A, 2j0u:A, 6qdv:7, 2xb2:A, 2xb2:X, 5xjc:u, 5yzg:u, 7znj:A, 7znj:a, 7znj:F, 7znj:f, 7znj:K, 7znj:k
11 6uv1:A 438 112 0.0484 0.0685 0.2679 2.71e-05 6uv1:B, 6uv2:A, 6uv3:A, 6uv4:A
12 8arp:C 445 115 0.0468 0.0652 0.2522 4.37e-05 8arp:A, 8arp:B, 8arp:D, 8arp:E, 8arp:F
13 6x2f:A 1144 228 0.0806 0.0437 0.2193 4.62e-05 7ssg:A, 6x26:A, 6x2n:A, 6x43:A, 6x4w:A, 6x4y:A, 6x50:A
14 6x2f:A 1144 118 0.0484 0.0262 0.2542 0.18 7ssg:A, 6x26:A, 6x2n:A, 6x43:A, 6x4w:A, 6x4y:A, 6x50:A
15 6xeo:A 1118 228 0.0806 0.0447 0.2193 4.72e-05
16 6xeo:A 1118 118 0.0484 0.0268 0.2542 0.17
17 7bkp:A 689 116 0.0516 0.0464 0.2759 5.96e-05 6g19:A, 6gjz:A, 6gkh:A, 6gkm:A, 6h66:A, 7nic:A, 7niq:B
18 4kbf:A 365 92 0.0452 0.0767 0.3043 7.22e-05 2gxq:A, 2gxs:A, 2gxs:B, 2gxu:A, 3mwk:B, 3mwl:B, 3nbf:A, 3nbf:B, 3nbf:C, 3nbf:D
19 6s8r:A 167 104 0.0419 0.1557 0.2500 2.41e-04
20 2vso:A 366 77 0.0403 0.0683 0.3247 2.83e-04 1fuk:A, 2vso:B, 2vsx:A, 2vsx:B
21 6l5n:A 377 102 0.0548 0.0902 0.3333 4.97e-04 6l5m:A, 6l5m:B, 6l5m:C, 6l5m:D, 6l5m:E, 6l5n:B, 6l5o:A
22 6b4i:F 426 99 0.0500 0.0728 0.3131 5.37e-04 6b4i:E, 6b4j:E, 6b4j:F, 6b4k:A, 6b4k:B, 3ews:A, 3ews:B, 3fht:A, 3fht:B, 3fmo:B, 3fmp:B, 3fmp:D, 3g0h:A
23 8dg5:A 1635 84 0.0387 0.0147 0.2857 0.001 8dg7:A
24 8dfv:A 1664 68 0.0355 0.0132 0.3235 0.001
25 5jbj:A 627 131 0.0500 0.0494 0.2366 0.002
26 5jc3:A 668 85 0.0435 0.0404 0.3176 0.002 5jc3:B, 5jc7:B, 5jcf:A, 5jcf:B, 5jch:A, 5jch:B
27 5jc7:A 641 85 0.0435 0.0421 0.3176 0.003
28 5jb2:A 670 125 0.0500 0.0463 0.2480 0.003 5jaj:A, 5jbg:A
29 4d26:A 430 117 0.0532 0.0767 0.2821 0.003 4d25:A
30 4ljy:A 451 122 0.0452 0.0621 0.2295 0.003 7oqb:p, 7oqe:p
31 6dgd:A 704 99 0.0500 0.0440 0.3131 0.003 6dgd:B, 4nl4:H
32 6xki:A 378 80 0.0484 0.0794 0.3750 0.004 5zbz:A, 5zc9:A
33 1gm5:A 729 181 0.0597 0.0508 0.2044 0.004
34 5zal:A 1314 69 0.0387 0.0183 0.3478 0.005 2eb1:A, 2eb1:B, 2eb1:C, 4ngd:A, 5zam:A
35 7tra:A 572 136 0.0661 0.0717 0.3015 0.005
36 4ct4:B 378 104 0.0403 0.0661 0.2404 0.007 5anr:B, 4ct4:D, 1vec:A, 2wax:C, 2way:A
37 8i9v:Cb 642 105 0.0435 0.0421 0.2571 0.007 8i9t:Cb, 8i9w:Cb, 8i9x:Cb
38 6p4f:C 436 69 0.0323 0.0459 0.2899 0.009 6p4f:A, 6p4w:A
39 2rb4:A 164 75 0.0339 0.1280 0.2800 0.010
40 7yym:A 1281 69 0.0371 0.0180 0.3333 0.010 4ngb:A, 4ngc:A, 4ngg:A, 4nh3:A, 4nh5:A, 4nh6:A, 7yyn:A, 7zpi:A, 7zpj:A, 7zpk:A
41 7liu:A 442 102 0.0484 0.0679 0.2941 0.012 6cz5:A, 5e7j:A, 5e7m:A, 2i4i:A, 7liu:B, 4px9:A, 4px9:B, 4px9:C, 4pxa:A, 8ssw:A, 8ssw:B
42 4w7s:B 448 90 0.0452 0.0625 0.3111 0.032
43 8dga:A 1629 62 0.0323 0.0123 0.3226 0.034
44 6dcr:B 600 58 0.0339 0.0350 0.3621 0.035
45 8y6o:I 597 104 0.0435 0.0452 0.2596 0.035 8qp8:G, 6qw6:5X, 6qx9:5X, 8r08:G
46 8fak:H 643 66 0.0371 0.0358 0.3485 0.037 2d7g:A, 2d7g:B, 2d7g:C, 2d7g:D, 2d7h:A, 6dcr:A, 2dwl:A, 2dwl:B, 2dwl:C, 2dwl:D, 2dwm:A, 2dwm:C, 2dwm:D, 2dwn:A, 2dwn:C
47 7bkq:A 640 87 0.0387 0.0375 0.2759 0.039
48 6m6a:M 459 53 0.0323 0.0436 0.3774 0.041 6m6b:M
49 8i9z:CE 465 93 0.0403 0.0538 0.2688 0.041 8i9p:CE, 8i9r:CE, 8i9t:CE, 8i9v:CE, 8i9w:CE, 8i9x:CE, 8i9y:CE, 8ia0:CE
50 7a8r:A 531 123 0.0452 0.0527 0.2276 0.099 7a8r:B, 6jtz:A, 6jtz:B, 4u7d:A, 4u7d:B, 4u7d:D, 4u7d:C, 2v1x:A, 2v1x:B, 2wwy:B, 2wwy:A, 8yrs:B, 8yrs:A
51 5dtu:A 404 70 0.0339 0.0520 0.3000 0.11
52 5v9x:A 772 110 0.0484 0.0389 0.2727 0.16
53 4xqk:A 1517 51 0.0274 0.0112 0.3333 0.18 4xqk:B
54 8fkv:NI 647 115 0.0452 0.0433 0.2435 0.20 8fkt:NI, 8fku:NI, 8fkw:NI, 8fkx:NI, 8fky:NI
55 7pmq:C 458 76 0.0339 0.0459 0.2763 0.20 7pli:A, 7pli:B, 7pli:J, 7pli:E, 7pli:F, 7pli:I, 7pmm:A, 7pmm:B, 7pmq:D, 7pmq:A, 7pmq:B
56 7am2:BW 447 92 0.0419 0.0582 0.2826 0.20
57 8t5s:A 693 94 0.0452 0.0404 0.2979 0.22
58 2db3:A 420 113 0.0435 0.0643 0.2389 0.38 2db3:B, 2db3:C, 2db3:D
59 8fzi:v 525 60 0.0339 0.0400 0.3500 0.45 8fzd:v, 8fzf:v, 8fzg:v, 8fzj:v, 6gwt:w, 6gxm:w, 6gxn:w, 6gxo:w, 6gxp:w, 2h5e:A, 2h5e:B, 6lkq:v, 7m5d:7, 4v85:AW, 4v89:AW, 4v8o:AY
60 6raf:A 588 55 0.0323 0.0340 0.3636 1.0 6rag:A, 6rah:A, 6rai:A, 6raj:A, 6rak:A, 6ral:A, 6ram:A
61 4gl2:A 617 133 0.0548 0.0551 0.2556 1.1 4gl2:B
62 4nl8:E 571 80 0.0323 0.0350 0.2500 1.1 4nl8:B
63 8v87:3 656 90 0.0339 0.0320 0.2333 1.1 8v84:3
64 7w0b:A 1586 69 0.0323 0.0126 0.2899 1.2 7w0d:F
65 5z3g:Y 438 109 0.0403 0.0571 0.2294 1.2 6c0f:p, 6cb1:p, 8e5t:p, 7nac:D, 7ohr:D, 7ohs:D, 7ohv:D, 7ohw:D, 7ohx:D, 7r6q:D, 7r7a:D, 8v87:D
66 4gki:A 272 124 0.0548 0.1250 0.2742 1.2 4ej7:A, 4ej7:B, 4ej7:C, 4feu:A, 4feu:B, 4feu:C, 4feu:D, 4feu:E, 4feu:F, 4fev:A, 4fev:B, 4fev:C, 4fev:D, 4fev:E, 4fev:F, 4few:A, 4few:B, 4few:C, 4few:D, 4few:E, 4few:F, 4fex:A, 4fex:B, 4fex:C, 4fex:D, 4fex:E, 4gkh:A, 4gkh:B, 4gkh:C, 4gkh:D, 4gkh:E, 4gkh:F, 4gkh:G, 4gkh:H, 4gkh:I, 4gkh:J, 4gkh:K, 4gkh:L, 4gki:B, 4gki:C, 4gki:D, 4gki:E, 4gki:F, 4gki:G, 4gki:H, 4gki:I, 4gki:J, 4gki:K, 4gki:L
67 8hf0:A 1561 69 0.0323 0.0128 0.2899 1.3 8hf0:D, 8hf1:A, 8hf1:D, 8hf1:G, 7w0a:A, 7w0a:E, 7w0c:A, 7w0d:A, 7w0e:A, 7w0f:A
68 7v6c:A 1540 69 0.0323 0.0130 0.2899 1.3
69 8xaw:B 567 66 0.0290 0.0317 0.2727 1.6 8xaw:C, 8xaw:D, 8xaw:E, 8xaw:A, 8xaw:F, 8xax:A, 8xax:B, 8xax:C, 8xax:D, 8xax:E, 8xax:F, 8xay:B, 8xay:C, 8xay:D, 8xay:E, 8xay:A, 8xay:F
70 3vma:A 708 74 0.0339 0.0297 0.2838 1.7 5fgz:A, 3fwl:A, 5hl9:A, 5hla:A, 6yn0:A
71 5hlb:A 733 74 0.0339 0.0286 0.2838 1.8
72 5hld:A 649 74 0.0339 0.0324 0.2838 1.9
73 5lst:A 617 71 0.0355 0.0357 0.3099 2.3
74 7r7j:B 574 62 0.0242 0.0261 0.2419 2.7 8h5y:B, 8h5y:A, 8h5z:B, 8h5z:A, 6jde:B, 6jde:A, 7r7j:A
75 7r7j:B 574 54 0.0290 0.0314 0.3333 9.3 8h5y:B, 8h5y:A, 8h5z:B, 8h5z:A, 6jde:B, 6jde:A, 7r7j:A
76 1oyw:A 516 153 0.0532 0.0640 0.2157 3.1 1oyy:A
77 3hws:D 316 86 0.0387 0.0759 0.2791 3.1 3hws:B, 3hws:E, 4i4l:A, 4i81:A, 4i81:B
78 8et3:C 353 70 0.0323 0.0567 0.2857 3.6 8e7v:A, 8e7v:B, 8e7v:C, 8e7v:D, 8e7v:E, 8e7v:F, 8e8q:A, 8e8q:B, 8e8q:C, 8e8q:D, 8e8q:E, 8e8q:F, 8e91:A, 8e91:B, 8e91:C, 8e91:D, 8e91:E, 8e91:F, 8et3:A, 8et3:B, 8et3:D, 8et3:E, 8et3:F, 6po1:A, 6po1:B, 6po1:C, 6po1:D, 6po1:E, 6po3:A, 6po3:B, 6po3:C, 6po3:D, 6po3:E, 6po3:F, 6pod:B, 6pod:C, 6pod:D, 6pod:E, 6pod:F, 6pos:B, 6pos:A, 6pos:C, 6pos:D, 6pos:E, 6pos:F, 6pp5:A, 6pp5:B, 6pp5:C, 6pp5:D, 6pp5:E, 6pp6:A, 6pp6:B, 6pp6:C, 6pp6:D, 6pp6:E, 6pp6:F, 6pp7:B, 6pp7:C, 6pp7:D, 6pp7:E, 6pp7:F, 6pp8:B, 6pp8:A, 6pp8:C, 6pp8:D, 6pp8:E, 6pp8:F, 6wrf:B, 6wrf:C, 6wrf:A, 6wrf:D, 6wrf:E, 6wrf:F, 6wsg:B, 6wsg:C, 6wsg:D, 6wsg:E, 6wsg:F
79 6yxy:EB 663 173 0.0548 0.0513 0.1965 4.0 7aoi:XB, 6yxx:EB
80 7eld:A 1137 74 0.0339 0.0185 0.2838 4.6 7ele:A
81 8wk0:N 542 59 0.0226 0.0258 0.2373 4.7
82 5sup:B 383 156 0.0597 0.0966 0.2372 4.7 5sup:A, 5sup:C, 5suq:A, 5suq:C
83 8dr0:D 344 59 0.0323 0.0581 0.3390 6.0 8dqw:D, 8dqx:D, 8dqz:D, 8dr1:D, 8dr3:D, 8dr4:D, 8dr5:D, 8dr6:D, 8dr7:D, 8fs3:D, 8fs4:D, 8fs5:D, 8fs6:D, 8fs7:D, 8fs8:D, 7sgz:D, 7sh2:D, 7st9:D, 7stb:D, 7ste:D, 1sxj:D, 7tfh:D, 7tfi:D, 7tfj:D, 7tfk:D, 7tfl:D, 7thj:D, 7thv:D, 8thb:D, 8thc:D, 8thd:D, 7ti8:D, 7tib:D, 7tic:D, 7tid:D, 7tku:D, 8tw7:2, 8tw8:2, 8twa:2, 8twb:2, 7u19:D, 7u1a:D, 7u1p:D
84 2hcf:A 225 125 0.0452 0.1244 0.2240 6.1
85 2o1b:A 376 49 0.0290 0.0479 0.3673 6.2
86 6o5f:A 417 58 0.0274 0.0408 0.2931 6.2 6o5f:B
87 4i81:E 290 42 0.0242 0.0517 0.3571 6.4 4i81:D
88 1gpj:A 399 64 0.0306 0.0476 0.2969 6.8
89 8wiv:O 657 25 0.0145 0.0137 0.3600 7.0 8wiv:M, 8wiv:L, 8wj3:M, 8wj3:O, 8wj3:L, 8wk0:M, 8wk0:O, 8wk0:L
90 8wiv:D 602 25 0.0145 0.0150 0.3600 7.0 8wk0:D
91 5c3c:B 235 43 0.0210 0.0553 0.3023 7.0 5c3c:A
92 2qie:A 136 58 0.0242 0.1103 0.2586 7.1 2qie:E, 2qie:H, 2qie:K
93 6uk3:A 475 33 0.0177 0.0232 0.3333 7.4 6uk3:C, 6uk3:B, 6uk3:D
94 7ljm:A 348 27 0.0177 0.0316 0.4074 7.6 7ljm:B
95 1w6u:A 288 74 0.0355 0.0764 0.2973 8.0 1w6u:B, 1w6u:C, 1w6u:D, 1w73:A, 1w73:B, 1w73:C, 1w73:D, 1w8d:A, 1w8d:B, 1w8d:C, 1w8d:D
96 7k5b:B 4524 85 0.0355 0.0049 0.2588 8.1 8bx8:B, 7k58:B, 7kek:B
97 2fsh:A 691 54 0.0274 0.0246 0.3148 8.6 3bxz:A, 3bxz:B, 2fsg:A, 2fsi:A
98 2fsi:B 748 54 0.0274 0.0227 0.3148 8.6 2fsg:B
99 2fsh:B 722 54 0.0274 0.0235 0.3148 9.1
100 5vog:A 176 104 0.0468 0.1648 0.2788 9.4
101 6s0k:h 838 54 0.0274 0.0203 0.3148 9.6 5k9t:A, 2vda:A
102 6pod:A 329 33 0.0194 0.0365 0.3636 10.0 3hws:A, 6po1:F, 6pp5:F, 6pp7:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218