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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSA
VYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRFTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIP
NLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRA
RAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQT
QLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPA
EAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQ
IAELLRILGSADRLMEVIREELELVREQFGDKRRTEITAN

The query sequence (length=520) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8qdx:C 837 520 1.0000 0.6213 1.0000 0.0 9gbv:A, 9gbv:C, 9ggq:C, 9ggq:A, 8qdx:A, 8qqi:A, 8qqi:C, 8qqs:A, 8qqs:C, 8qqu:C, 6rks:C, 6rks:A, 6rku:C, 6rku:A, 6rkv:C, 6rkv:A, 6rkw:C, 6rkw:A, 4tma:E, 2y3p:A, 2y3p:B, 7z9c:A, 7z9c:C, 7z9g:A, 7z9g:C, 7z9k:A, 7z9k:C, 7z9m:A, 7z9m:C
2 4ckl:A 450 489 0.8635 0.9978 0.9182 0.0
3 2xcr:D 719 515 0.5577 0.4033 0.5631 0.0 8bp2:AAA, 8bp2:CCC, 5cdm:A, 5cdm:C, 5cdn:C, 5cdn:A, 5cdn:T, 5cdn:R, 5cdo:A, 5cdo:C, 5cdo:R, 5cdo:T, 5cdp:A, 5cdp:C, 5cdq:A, 5cdq:C, 5cdq:R, 5cdq:T, 5cdr:A, 5cdr:C, 6fqm:A, 6fqm:C, 6fqm:a, 6fqm:c, 6fqs:A, 6fqs:C, 6fqv:A, 6fqv:C, 6fqv:R, 6fqv:T, 5iwi:A, 5iwi:C, 5iwm:A, 5iwm:C, 6qtk:A, 6qtk:C, 6qtp:A, 6qtp:C, 6qx1:A, 6qx1:C, 6qx2:A, 6qx2:C, 6qx2:J, 6qx2:L, 6qx2:R, 6qx2:T, 6qx2:a, 6qx2:c, 6qx2:j, 6qx2:l, 6qx2:r, 6qx2:t, 2xcr:B, 2xcr:S, 2xcr:U
4 7mvs:B 675 515 0.5577 0.4296 0.5631 0.0 8bp2:BBB, 8bp2:DDD, 5bs3:B, 5bs3:D, 4bul:A, 4bul:C, 5cdm:B, 5cdm:D, 5cdn:D, 5cdn:B, 5cdn:U, 5cdn:S, 5cdo:B, 5cdo:D, 5cdo:S, 5cdo:U, 5cdp:B, 5cdp:D, 5cdq:B, 5cdq:D, 5cdq:S, 5cdq:U, 5cdr:B, 5cdr:D, 6fm4:B, 6fm4:D, 6fqm:D, 6fqs:B, 6fqs:D, 6fqv:B, 6fqv:D, 6fqv:S, 6fqv:U, 7fvs:A, 7fvs:B, 7fvt:A, 7fvt:B, 5iwi:B, 5iwi:D, 5iwm:B, 5iwm:D, 7mvs:A, 5npk:B, 5npk:D, 5npk:b, 5npk:d, 5npp:B, 5npp:D, 4plb:B, 4plb:D, 6qtk:B, 6qtk:D, 6qtp:B, 6qtp:D, 6qx1:B, 6qx1:D, 6qx2:B, 6qx2:D, 6qx2:K, 6qx2:M, 6qx2:S, 6qx2:U, 6qx2:b, 6qx2:d, 6qx2:k, 6qx2:m, 6qx2:s, 6qx2:u, 2xcs:B, 2xcs:D, 2xct:B, 2xct:D, 2xct:S, 2xct:U, 6z1a:B, 6z1a:D
5 4z2c:A 485 516 0.5269 0.5649 0.5310 0.0 6n1p:A, 6n1p:G, 6n1p:B, 4z2c:B, 4z2d:A, 4z2d:B, 4z2e:A, 4z2e:B
6 2xco:A 636 497 0.5327 0.4355 0.5573 0.0
7 6gau:A 1088 522 0.4769 0.2279 0.4751 4.94e-158 5bs8:A, 5bs8:B, 5bs8:C, 5bs8:D, 5bta:A, 5bta:B, 5bta:C, 5bta:D, 5btc:A, 5btc:B, 5btc:C, 5btc:D, 5btd:A, 5btd:B, 5btd:C, 5btd:D, 5btf:A, 5btf:B, 5btf:C, 5btf:D, 5btg:A, 5btg:B, 5btg:C, 5btg:D, 5bti:A, 5bti:B, 5bti:C, 5bti:D, 5btl:A, 5btl:B, 5btl:C, 5btl:D, 5btn:A, 5btn:B, 5btn:C, 5btn:D, 9foy:A, 9foy:B, 6gau:B, 7ugw:A, 7ugw:B, 7ugw:C, 7ugw:D
8 8c41:A 720 514 0.4250 0.3069 0.4300 2.07e-143 8c41:B
9 4i3h:A 1037 514 0.4250 0.2131 0.4300 1.67e-139 3foe:D, 3foe:C, 3fof:C, 3fof:D, 4i3h:B, 4juo:A, 4juo:C, 3k9f:A, 3k9f:C, 3k9f:D, 3k9f:B, 4koe:A, 4koe:C, 4koe:D, 4koe:B, 4kpe:A, 4kpe:C, 4kpe:D, 4kpe:B, 4kpf:A, 4kpf:C, 4kpf:D, 4kpf:B, 3ksa:A, 3ksa:C, 3ksa:D, 3ksa:B, 3ksb:A, 3ksb:B, 3ksb:C, 3ksb:D, 3ltn:A, 3ltn:C, 3ltn:D, 3ltn:B, 3rad:A, 3rad:C, 3rad:D, 3rad:B, 3rae:A, 3rae:C, 3rae:D, 3rae:B, 3raf:A, 3raf:C, 3raf:D, 3raf:B, 4z3o:B, 4z3o:A, 4z4q:A, 4z4q:B, 4z53:A, 4z53:B
10 7lhz:C 714 515 0.4173 0.3039 0.4214 1.90e-120 5eix:A, 5eix:B, 7lhz:A, 6waa:B, 6waa:F
11 5eix:J 679 514 0.4096 0.3137 0.4144 3.29e-117 5eix:G, 7lhz:D
12 6waa:H 656 513 0.3981 0.3155 0.4035 1.44e-113 6waa:D
13 3fof:A 435 508 0.3827 0.4575 0.3917 9.54e-112 3foe:A, 3foe:B, 3fof:B
14 2xkk:C 711 517 0.3827 0.2799 0.3849 6.84e-110 2xkk:A
15 7lhz:B 631 513 0.3942 0.3249 0.3996 1.53e-109
16 8yo4:A 442 380 0.1904 0.2240 0.2605 3.94e-24 8ylu:A, 8ylu:B, 8yo4:B, 8yo7:A, 8yo7:B, 8yon:A, 8yon:B
17 8gcc:A 707 182 0.1192 0.0877 0.3407 7.17e-16 8gcc:B
18 5gwj:A 677 344 0.1673 0.1285 0.2529 9.50e-16 4g0u:A, 4g0u:B, 4g0v:A, 4g0v:B, 4g0w:A, 4g0w:B, 5gwi:A, 5gwi:B, 5gwj:B, 4j3n:A, 4j3n:B, 3qx3:A, 3qx3:B, 5zrf:A, 5zrf:B
19 7yq8:A 730 344 0.1673 0.1192 0.2529 1.08e-15 7yq8:B, 5zad:A, 5zad:B, 5zen:A, 5zqf:A
20 6zy7:B 1160 350 0.1750 0.0784 0.2600 1.91e-15 4fm9:A, 5gwk:A, 5gwk:B, 4r1f:B, 4r1f:C, 4r1f:D, 1zxm:A, 1zxm:B, 1zxn:B, 1zxn:C, 1zxn:D, 6zy5:B, 6zy5:A, 6zy6:A, 6zy6:B, 6zy7:A, 6zy8:A, 6zy8:B
21 4gfh:A 1102 477 0.2135 0.1007 0.2327 2.83e-15 4gfh:F, 3l4j:A, 3l4k:A, 1pvg:A, 1pvg:B, 1qzr:A, 1qzr:B, 2rgr:A
22 6koz:A 436 130 0.0635 0.0757 0.2538 0.86 6a8z:A, 6a8z:B, 6iff:A, 6iff:B, 6ifg:A, 6ifg:B, 6koy:A, 6koy:B, 6koz:B, 6kp0:A, 6kp0:B, 6kp1:A, 6kp1:B
23 6je4:O 1049 80 0.0423 0.0210 0.2750 3.1 8hj4:A, 8ja0:A, 6je9:C
24 3d2e:A 629 108 0.0558 0.0461 0.2685 3.3 3d2e:C, 3d2f:A, 3d2f:C, 2qxl:A, 2qxl:B
25 3c7n:A 649 108 0.0558 0.0447 0.2685 4.3
26 7pq3:BBB 269 58 0.0327 0.0632 0.2931 4.7 7pq3:AAA
27 7rkt:A 452 161 0.0635 0.0730 0.2050 7.1 6ay4:A, 6ay6:A, 6ayb:A, 6ayc:A, 7rkr:A, 7rkw:A, 7rtq:A, 7rtq:B, 7rtq:C, 7rtq:D, 5tl8:A
28 3s20:A 344 61 0.0346 0.0523 0.2951 7.4 6b2u:A, 4ku2:B, 4ku3:B, 4ku5:B, 3s20:B, 3s21:A, 3s23:A, 5vxe:A, 5vxg:A, 5vxi:A
29 5mq4:C 117 64 0.0385 0.1709 0.3125 8.1 5mq4:A, 5mq4:B, 5mq4:D, 5mq4:E, 5mq4:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218