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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AQRLDGARFRYLNEQLYSGPSSAAQRLFQEDPEAFLLYHRGFQSQVKKWPLQPVDRIARDLRQRPASLVVADFGCGDCRL
ASSIRNPVHCFDLASLDPRVTVCDMAQVPLEDESVDVAVFCLSLMGTNIRDFLEEANRVLKPGGLLKVAEVSSRFEDVRT
FLRAVTKLGFKIVSKDLTNSHFFLFDFQKTGPPLVGPKAQLSGLQLQPCLYK

The query sequence (length=212) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2zfu:A 212 212 1.0000 1.0000 1.0000 7.81e-157 2zfu:B
2 5gm2:K 267 140 0.2075 0.1648 0.3143 1.50e-05
3 5gm2:B 282 106 0.1651 0.1241 0.3302 0.002 5gm1:A, 5gm1:B, 5gm1:C, 5gm1:D, 5gm1:E, 5gm1:F, 5gm1:G, 5gm1:H, 5gm1:I, 5gm1:J, 5gm1:K, 5gm1:L, 5gm1:M, 5gm1:N, 5gm1:O, 5gm1:P, 5gm1:Q, 5gm1:R, 5gm2:A, 5gm2:C, 5gm2:D, 5gm2:E, 5gm2:F, 5gm2:G, 5gm2:H, 5gm2:I, 5gm2:J, 5gm2:L, 5gm2:M, 5gm2:N, 5gm2:O, 5gm2:P, 5gm2:Q, 5gm2:R
4 2yqz:A 261 57 0.1179 0.0958 0.4386 0.022 2yqz:B
5 4pne:B 272 104 0.1462 0.1140 0.2981 0.027 4pne:A
6 1wg8:A 281 133 0.1651 0.1246 0.2632 0.16 1wg8:B
7 3la3:A 198 68 0.0896 0.0960 0.2794 0.26 8h3v:X, 8h3v:Y, 8h40:X, 8h40:Y, 3la2:A, 3la2:B, 3la3:B
8 4ww9:A 238 120 0.1698 0.1513 0.3000 0.35 4ww5:A, 4ww7:A
9 3w0l:B 598 90 0.1179 0.0418 0.2778 0.49 3w0l:D
10 7fbo:A 282 53 0.0849 0.0638 0.3396 0.62 7fbh:B, 7fbh:C, 7fbo:B, 7fbo:C
11 1z7z:3 192 32 0.0566 0.0625 0.3750 0.63
12 5x62:B 387 35 0.0708 0.0388 0.4286 1.5 5x62:A
13 6dt1:A 464 49 0.0708 0.0323 0.3061 1.6 6dt1:E
14 1qzz:A 340 86 0.1132 0.0706 0.2791 1.6 1r00:A, 1xds:A, 1xds:B, 1xdu:A
15 4f86:A 275 46 0.0708 0.0545 0.3261 1.7 4f84:A, 4f86:B, 4f86:C, 4f86:E, 4f86:F, 4f86:H, 4f86:I, 4f86:J, 4f86:K, 4f86:L
16 3bus:A 251 60 0.1085 0.0916 0.3833 2.0 3bus:B
17 1i9g:A 264 64 0.0991 0.0795 0.3281 2.2
18 2gs9:A 211 43 0.0802 0.0806 0.3953 3.7 2gs9:B
19 4obw:D 235 60 0.0991 0.0894 0.3500 3.8 4obw:A, 4obw:C, 4obw:B
20 5yf0:B 351 85 0.0896 0.0541 0.2235 3.8 5yf0:A, 5yf1:A, 5yf1:B, 5yf2:A, 5yf2:B
21 6cx6:B 333 41 0.0708 0.0450 0.3659 4.7 6cx6:A, 5eg5:A, 4fr0:A, 4fsd:A, 4kw7:A, 4rsr:A
22 5v96:A 467 27 0.0519 0.0236 0.4074 5.5 5v96:B, 5v96:C, 5v96:D
23 4zwu:A 435 54 0.0708 0.0345 0.2778 5.8 3l24:A, 3l7g:A, 4zwo:A, 4zwo:B, 4zwp:A, 4zwp:B, 4zwu:B
24 7tj9:A 1111 53 0.0896 0.0171 0.3585 5.8
25 3l24:B 417 54 0.0708 0.0360 0.2778 6.0 3l24:C, 3l7g:B, 3l7g:C
26 7v6h:A 267 81 0.1085 0.0861 0.2840 6.7 7v6h:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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