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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
APVPRTGIIAGFNKGYKTTRRARRPSSNDRYALPHKKLRAVKAIISDLVGFSPMERRVQELLRVGKDKRALKFCKKRLGS
IKAAKKRRAKVEEALRQQ

The query sequence (length=98) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4v8m:Bm 106 98 1.0000 0.9245 1.0000 5.67e-67 8ova:Bm, 8ove:Bm, 5t5h:m
2 8rxh:Li 102 97 0.7551 0.7255 0.7629 3.53e-51 8a98:i, 6az3:i, 3jcs:i, 8rxx:Li, 5t2a:k
3 8a3w:i 86 97 0.6735 0.7674 0.6804 1.54e-39 8ovj:i
4 7qiw:k 100 94 0.4286 0.4200 0.4468 3.05e-23 8azw:U, 8b2l:U3, 7qiz:k
5 7olc:Li 102 96 0.4898 0.4706 0.5000 2.22e-22 8i9p:Li, 8i9r:Li, 8i9t:Li, 8i9v:Li, 8i9w:Li, 8i9x:Li, 8i9y:Li, 8i9z:Li, 8ia0:Li, 7old:Li, 8oo0:Li, 8pv1:Li, 8pv2:Li, 8pv3:Li, 8pv4:Li, 8pv5:Li, 8pv6:Li, 8pv7:Li, 8pv8:Li, 8pvk:Li, 8pvl:Li, 7z3n:Li, 7z3o:Li
6 8ip8:AB 100 94 0.4184 0.4100 0.4362 2.74e-22 8ipa:AB, 8ipb:AB, 8jiv:Ci
7 6zj3:Lx 102 71 0.3878 0.3725 0.5352 3.42e-19
8 9bh5:Ci 104 89 0.3469 0.3269 0.3820 9.85e-18 9cai:Ci
9 7qgg:j 104 91 0.3878 0.3654 0.4176 3.15e-17 7a01:B2, 8a3d:c, 5aj0:Ai, 8b5l:i, 8b6c:i, 9bdl:AL36, 9bdn:AL36, 9bdp:AL36, 7bhp:Li, 8bhf:V1, 8bpo:h2, 8btk:Bi, 7cpu:Li, 7cpv:Li, 4d5y:i, 4d67:i, 6d90:i, 6d9j:i, 9f1b:Bi, 9f1c:Bi, 9f1d:Bi, 7f5s:Li, 8fkp:LU, 8fkq:LU, 8fkr:LU, 8fks:LU, 8fkt:LU, 8fku:LU, 8fkv:LU, 8fkw:LU, 8fkx:LU, 8fky:LU, 8fkz:LU, 8fl2:LU, 8fl3:LU, 8fl4:LU, 8fl6:LU, 8fl7:LU, 8fl9:LU, 8fla:LU, 8flb:LU, 8flc:LU, 8fld:LU, 8fle:LU, 8flf:LU, 6frk:i, 6ftg:i, 6fti:i, 6ftj:i, 8g5y:Li, 8g5z:Li, 8g60:Li, 8g61:Li, 8g6j:Li, 8glp:Li, 6gz3:Ai, 6gz4:Ai, 6gz5:Ai, 6hcf:i3, 6hcj:i3, 6hcm:i3, 6hcq:i3, 8idt:K, 8idy:K, 8ie3:K, 8ifd:2c, 8ife:2c, 8ine:K, 8inf:K, 8ink:K, 6ip5:2c, 6ip6:2c, 6ip8:2c, 8ipd:K, 8ipx:K, 8ipy:K, 8ir1:K, 8ir3:K, 3j7o:i, 3j7p:i, 3j7q:i, 3j7r:i, 3j92:i, 3jag:i, 3jah:i, 3jai:i, 3jaj:i, 3jan:i, 8jdj:n, 8jdk:n, 8jdl:n, 8jdm:n, 8k2c:Li, 5lks:Li, 6lqm:K, 6lsr:K, 6lss:K, 7ls1:c2, 7ls2:c2, 6lu8:K, 5lzs:i, 5lzt:i, 5lzu:i, 5lzv:i, 5lzw:i, 5lzx:i, 5lzy:i, 5lzz:i, 7mdz:i, 6mtb:i, 6mtc:i, 6mtd:i, 6mte:i, 7nfx:i, 7nwg:i3, 7nwh:i, 7nwi:i, 7o7y:Bi, 7o7z:Bi, 7o80:Bi, 7o81:Bi, 7obr:i, 8ohd:Li, 8oj0:Li, 8oj5:Li, 8oj8:Li, 6ole:j, 6olf:j, 6olg:Ai, 6oli:j, 6olz:Ai, 6om0:j, 6om7:j, 7ow7:c, 7oya:i1, 7oyb:i1, 7oyc:i1, 7oyd:i, 8p2k:Bi, 6p5i:Ai, 6p5j:Ai, 6p5k:Ai, 6p5n:Ai, 8q7z:Bi, 8q87:Bi, 8qfd:i, 8qoi:Li, 7qvp:Li, 7qvp:Mi, 7qwq:i, 7qwr:i, 7qws:i, 6qzp:Li, 6r5q:i, 6r6g:i, 6r6p:i, 6r7q:i, 8rjb:i, 8rjc:i, 8rjd:i, 8scb:i, 6sgc:i2, 6swa:g, 5t2c:c, 6t59:i3, 7tm3:i, 7toq:AL36, 7tor:AL36, 7tut:i, 7ucj:i, 7uck:i, 4ug0:Li, 4ujc:Bi, 4ujd:Ai, 4uje:Ci, 4v6x:Ci, 6w6l:j, 6xa1:Li, 7xnx:Li, 7xny:Li, 8xsx:Li, 8xsy:Li, 8xsz:Li, 6y0g:Li, 8y0w:Li, 8y0x:Li, 6y2l:Li, 6y57:Li, 6y6x:Li, 8yoo:Li, 8yop:Li, 6z6l:Li, 6z6m:Li, 6z6n:Li, 7zjw:Ll, 7zjx:Ll, 6zm7:Li, 6zme:Li, 6zmi:Li, 6zmo:Li, 6zvk:B2
10 7r81:k1 96 92 0.4184 0.4271 0.4457 4.31e-16
11 8eth:i 98 87 0.3776 0.3776 0.4253 6.86e-15 8esq:i, 8esr:i, 8etc:i, 8etg:i, 8eti:i, 8etj:i, 8eug:i, 8eui:i, 8eup:i, 8euy:i, 8ev3:i
12 4v3p:Lk 77 62 0.3061 0.3896 0.4839 4.05e-14 4v7e:Ci
13 5xxb:h 97 96 0.3571 0.3608 0.3646 2.18e-13
14 3j79:b 95 98 0.3367 0.3474 0.3367 3.65e-13 3jbn:Ab, 3jbo:Ab, 3jbp:Ab, 8tpu:Ab, 5umd:b
15 8aaf:V 99 89 0.3673 0.3636 0.4045 1.17e-12 8agt:V, 8agu:V, 8agv:V, 8agw:V, 8agx:V, 8agz:V, 5apn:i, 5apo:i, 7azy:d, 7b7d:Le, 8bip:Li, 8bjq:Li, 8bn3:O6, 8bqd:AC, 8bqx:AC, 7bt6:i, 7btb:i, 6c0f:i, 6cb1:i, 8ccs:U, 8cdl:U, 8cdr:U, 8ceh:U, 8cf5:U, 8cg8:U, 8cgn:U, 8civ:U, 8cku:U, 8cmj:U, 5dat:O6, 5dat:o6, 5dc3:O6, 5dc3:o6, 5dge:O6, 5dge:o6, 5dgf:O6, 5dgf:o6, 5dgv:O6, 5dgv:o6, 8e5t:i, 6elz:i, 6em1:i, 6em3:i, 6em4:i, 6em5:i, 8eub:Ai, 8evp:Ai, 8evq:Ai, 8evr:Ai, 8evs:Ai, 8evt:Ai, 8ewb:Ai, 8ewc:Ai, 5fci:O6, 5fci:o6, 5fcj:O6, 5fcj:o6, 6ft6:i, 5gak:k, 6gq1:i, 6gqb:i, 6gqv:i, 5h4p:i, 6hd7:k, 8hfr:ia, 6hhq:AJ, 6hhq:DK, 5i4l:O6, 5i4l:o6, 6i7o:AC, 6i7o:XC, 3j6x:76, 3j6y:76, 3j77:86, 3j78:86, 3jct:i, 5jcs:i, 5juo:NA, 5jup:NA, 5jus:NA, 5jut:NA, 5juu:NA, 8k2d:Li, 8k82:Li, 5lyb:O6, 5lyb:o6, 5m1j:i5, 6m62:i, 5mc6:AC, 5mei:AJ, 5mei:DK, 7mpi:Ai, 7mpj:Ai, 6n8j:i, 6n8k:i, 6n8l:i, 6n8m:v, 6n8n:v, 6n8o:v, 7n8b:Ai, 7nac:i, 5ndg:O6, 5ndg:o6, 5ndv:O6, 5ndv:o6, 5ndw:O6, 5ndw:o6, 7nrc:Lk, 7nrd:Lk, 5obm:O6, 5obm:o6, 7of1:i, 7oh3:i, 7ohp:i, 7ohq:i, 7ohr:i, 7ohs:i, 7ohu:i, 7ohv:i, 7ohw:i, 6oig:i, 5on6:AJ, 5on6:DK, 7osa:eL36, 7osm:eL36, 8p8m:RI, 8p8n:RI, 8p8u:RI, 8pfr:RI, 6q8y:AC, 6qik:h, 6qt0:h, 6qtz:h, 7r6k:i, 7r7a:i, 6r84:k, 6r86:k, 6r87:k, 6ri5:h, 7rr5:Li, 6rzz:h, 6s05:h, 6s47:Ak, 6snt:ah, 6sv4:AC, 6sv4:XC, 6sv4:zC, 6t4q:Li, 5t62:v, 5t6r:v, 6t7i:Li, 6t7t:Li, 6t83:ib, 6t83:T, 5tbw:AJ, 5tbw:DK, 6tb3:AC, 5tga:O6, 5tga:o6, 5tgm:O6, 5tgm:o6, 6tnu:AC, 7too:AL36, 7top:AL36, 7u0h:i, 4u3m:O6, 4u3m:o6, 4u3n:O6, 4u3n:o6, 4u3u:O6, 4u3u:o6, 4u4n:O6, 4u4n:o6, 4u4o:O6, 4u4o:o6, 4u4q:O6, 4u4q:o6, 4u4r:O6, 4u4r:o6, 4u4u:O6, 4u4u:o6, 4u4y:O6, 4u4y:o6, 4u4z:O6, 4u4z:o6, 4u50:O6, 4u50:o6, 4u51:O6, 4u51:o6, 4u52:O6, 4u52:o6, 4u53:O6, 4u53:o6, 4u55:O6, 4u55:o6, 4u56:O6, 4u56:o6, 4u6f:O6, 4u6f:o6, 7ug6:i, 7uoo:i, 7uqb:i, 7uqz:i, 7v08:i, 4v6i:Bk, 4v7f:g, 4v88:Bi, 4v88:Di, 4v8t:i, 4v8y:Bi, 4v8z:Bi, 8v83:i, 8v84:i, 8v87:i, 4v91:i, 6woo:i, 6xiq:i, 6xir:i, 8y0u:Li, 6ylg:i, 6ylh:i, 6ylx:i, 6yly:i, 5z3g:m, 7z34:i, 6z6j:Li, 6z6k:Li, 7zpq:Bh, 7zrs:Bh, 7zs5:Bj, 7zuw:Bh, 7zux:Eh, 7zw0:Ll
16 4v6w:Ci 113 97 0.3367 0.2920 0.3402 3.12e-12 6xu6:Ci, 6xu7:Ci, 6xu8:Ci
17 4v8p:AQ 102 98 0.3776 0.3627 0.3776 3.96e-12 4v8p:DQ, 4v8p:FQ, 4v8p:HQ
18 8br8:Lj 89 85 0.3367 0.3708 0.3882 8.02e-12 8brm:Lj, 8bsi:Lj, 8bsj:Lj, 8btd:Lj, 8btr:Lj, 8fru:i, 7pwg:i, 7pwo:i2
19 5it7:ii 98 89 0.3469 0.3469 0.3820 5.00e-11 6uz7:Bi
20 8p5d:LII 97 54 0.2653 0.2680 0.4815 8.22e-08 8p60:LII, 8p60:KII, 7qca:LII
21 5xy3:i 73 63 0.2041 0.2740 0.3175 2.23e-07
22 7pzy:AJ 98 61 0.2245 0.2245 0.3607 5.64e-07 8c3a:AJ, 8c3a:CD, 8cq7:AJ, 8cq7:CD, 8cqw:AJ, 8cqw:CD, 8cre:AJ, 8cre:CD, 8oeq:AJ, 8oeq:CD, 7q08:AJ, 7q0f:AJ, 7q0p:AJ, 7q0r:AJ, 8q5i:AJ
23 6zu5:LII 97 57 0.1837 0.1856 0.3158 1.26e-05
24 7qep:O6 94 54 0.2143 0.2234 0.3889 0.003
25 6rm3:LII 93 46 0.1429 0.1505 0.3043 0.072
26 7r6q:i 58 23 0.0918 0.1552 0.3913 0.79
27 8hbf:A 522 46 0.1224 0.0230 0.2609 2.3 7d9r:A, 7d9s:A, 7d9u:A, 8hbh:A, 6jt2:A
28 2c21:A 139 24 0.1020 0.0719 0.4167 3.5 2c21:B, 2c21:C, 2c21:D, 2c21:E, 2c21:F
29 6bnn:A 282 25 0.1224 0.0426 0.4800 6.3 6bnx:A, 6bnz:A, 5d7z:A
30 8vxy:B 1161 44 0.1633 0.0138 0.3636 7.0
31 8vxa:A 1139 44 0.1633 0.0140 0.3636 8.5 8vxc:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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