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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ALADISGYLDVLDSVRGFSYLENAREVLRSGEARCLGNPRSEPEYVKALYVIGASRIPVGDGCSHTLEELGVFDISVPGE
MVFPSPLDFFERGKPTPLVRSRLQLPNGVRVWLKLEWYNPFSLSVADRPAVEIISRLSRRVEKGSLVADATSSNFGVALS
AVARLYGYRARVYLPGAAEEFGKLLPRLLGAQVIVDPEAPSTVHLLPRVMKDSKNEGFVHVNQYYNDANFEAHMRGTARE
IFVQSRRGGLALRGVAGSLGTSGHMSAAAFYLQSVDPSIRAVLVQPAQGDSIPGIARVETGMLWINMLDISYTLAEVTLE
EAMEAVVEVARSDGLVIGPSGGAAVKALAKKAAEGDLEPGDYVVVVPDTGFKYLSLVQNALE

The query sequence (length=382) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5b36:B 383 382 0.9921 0.9896 0.9921 0.0 5b36:A, 5b3a:A, 5b3a:B, 6l0p:A, 6l0p:B, 6l0p:C, 6l0p:D, 6l0q:A, 6l0q:B, 6l0q:C, 6l0q:D, 6l0r:A, 6l0r:B, 6l0r:C, 6l0r:D, 6l0s:A, 6l0s:B, 6l0s:C, 6l0s:D, 3vsa:A, 3vsa:B, 3vsc:A, 3vsc:B, 3vsd:A, 3vsd:B, 1wkv:A, 1wkv:B
2 2bht:A 294 290 0.2435 0.3163 0.3207 1.67e-25 2bhs:A, 2bhs:B, 2bhs:C, 2bhs:D, 2bht:B, 2bht:C, 2bht:D, 2jc3:A, 2jc3:H, 2jc3:B, 2jc3:C, 2jc3:D, 2jc3:E, 2jc3:F, 2jc3:G, 2v03:A
3 3bm5:A 338 300 0.2225 0.2515 0.2833 6.17e-21 3bm5:B, 4il5:A, 4jbl:B, 4jbn:A, 2pqm:A, 2pqm:B
4 2eco:A 302 299 0.2356 0.2980 0.3010 8.54e-19 2ecq:A, 2efy:A, 2efy:B, 1ve1:A
5 8b9y:C 330 292 0.2173 0.2515 0.2842 2.68e-18 8b9y:A, 8b9y:B, 8b9y:D
6 8b9w:A 329 294 0.2225 0.2584 0.2891 1.85e-17 8b9w:B
7 6kr5:B 336 298 0.2068 0.2351 0.2651 7.14e-17 6kr5:A
8 3t4p:A 319 280 0.2042 0.2445 0.2786 2.91e-15 3tbh:A
9 2q3d:A 306 292 0.2225 0.2778 0.2911 3.24e-15 2q3c:A, 3zei:A
10 3dwg:A 325 276 0.2068 0.2431 0.2862 5.65e-15 3dwg:B, 3dwi:A, 3dwi:B, 5i6d:B, 5i6d:C, 5i6d:D, 5i7a:B, 5i7a:C, 5i7a:D, 5i7h:B, 5i7h:C, 5i7h:D, 5i7o:B, 5i7o:C, 5i7o:D, 5i7r:B, 5i7r:A, 5iw8:A, 5iw8:B
11 4air:A 304 272 0.1885 0.2368 0.2647 2.16e-14 4air:B
12 5xem:A 302 300 0.2173 0.2748 0.2767 2.89e-14 5xem:B, 5xen:A, 5xen:B, 5xeo:A, 5xeo:B
13 5xoq:A 310 292 0.2094 0.2581 0.2740 3.86e-14 5xoq:B
14 6c2h:A 345 311 0.2173 0.2406 0.2669 5.01e-14 6c2q:A, 6c2z:A, 6c4p:A
15 1d6s:A 322 306 0.2094 0.2484 0.2614 5.47e-14 1d6s:B, 1fcj:A, 1fcj:B, 1fcj:C, 1fcj:D, 1oas:A, 1oas:B, 6z4n:AAA, 6z4n:BBB
16 3x44:A 321 315 0.2408 0.2866 0.2921 8.01e-14 3x43:A, 3x43:B, 3x43:C, 3x43:D, 3x43:E, 3x43:F, 3x43:G, 3x43:H, 3x44:B
17 8h4q:N 488 256 0.1754 0.1373 0.2617 4.68e-13 8h4h:N, 8h4h:A, 8h4q:A
18 7mfj:BBB 319 315 0.2068 0.2476 0.2508 9.35e-13
19 5iwc:A 297 272 0.2094 0.2694 0.2941 1.52e-12 5i6d:A, 5i7a:A, 5i7h:A, 5i7o:A, 5iwc:B
20 8s5h:A 507 313 0.2225 0.1677 0.2716 2.07e-12 4coo:A, 4coo:B, 1jbq:A, 1jbq:B, 1jbq:C, 1jbq:D, 1jbq:E, 1jbq:F, 4l0d:A, 4l0d:B, 4l27:B, 4l27:D, 4l27:A, 4l27:C, 4l28:A, 4l28:B, 4l28:C, 4l28:D, 4l3v:B, 4l3v:A, 4l3v:C, 1m54:A, 1m54:B, 1m54:C, 1m54:D, 1m54:E, 1m54:F, 5mms:A, 5mms:F, 5mms:B, 5mms:C, 5mms:D, 5mms:E, 4pcu:A, 4pcu:B, 7qgt:A, 7qgt:B, 8s5h:B, 8s5h:C, 8s5h:D, 8s5h:E, 8s5h:F, 8s5h:G, 8s5h:H, 8s5i:A, 8s5i:B, 8s5i:C, 8s5i:D, 8s5i:E, 8s5i:F, 8s5j:A, 8s5j:B, 8s5j:C, 8s5j:D, 8s5j:E, 8s5j:F, 8s5j:G, 8s5j:H, 8s5j:I, 8s5j:J, 8s5k:A, 8s5k:B, 8s5k:C, 8s5k:D, 8s5k:E, 8s5k:F, 8s5k:G, 8s5k:H, 8s5l:A, 8s5l:B, 8s5l:C, 8s5l:D, 8s5m:A, 8s5m:B, 8s5m:C, 8s5m:D, 8s5m:E, 8s5m:F, 8s5m:G, 8s5m:H, 8s5m:I, 8s5m:J, 8stw:A, 8stw:B, 8stw:C, 8stw:D, 8stw:E, 8stw:F, 4uuu:A, 4uuu:B
21 6xo2:A 294 311 0.2042 0.2653 0.2508 2.17e-12 7mfj:AAA, 6pmu:A, 6pmu:B
22 7n2t:A 309 285 0.2147 0.2654 0.2877 6.19e-12
23 5b1i:A 303 294 0.2016 0.2541 0.2619 1.56e-11 5b1i:B, 5b1i:C, 5b1i:D, 5b1i:E, 5b1i:F, 5b1i:G, 5b1i:H
24 8if7:A 342 308 0.2539 0.2836 0.3149 3.24e-11
25 3vbe:C 329 298 0.2068 0.2401 0.2651 3.72e-11 3vbe:A, 3vbe:B, 3vbe:D, 3vc3:A, 3vc3:B, 3vc3:C, 3vc3:D, 3vc3:E, 3vc3:F
26 4lma:A 318 312 0.2304 0.2767 0.2821 5.65e-11 4lma:B
27 6ahi:B 306 285 0.2094 0.2614 0.2807 7.74e-11
28 5d84:A 318 303 0.1937 0.2327 0.2442 1.40e-10 5d85:A, 5d86:A, 5d87:A
29 4lmb:A 310 295 0.2147 0.2645 0.2780 3.22e-10
30 7xnz:B 458 300 0.2147 0.1790 0.2733 7.58e-10 7xnz:A, 7xnz:C, 7xnz:D, 7xoh:B, 7xoh:A, 7xoh:C, 7xoh:D, 7xoy:B, 7xoy:A, 7xoy:C, 7xoy:D
31 4aec:A 323 276 0.1885 0.2229 0.2609 1.34e-09 4aec:B
32 6vju:B 317 321 0.2042 0.2461 0.2430 1.78e-09
33 2isq:A 320 285 0.1911 0.2281 0.2561 3.23e-09 1z7w:A, 1z7y:A
34 5z5c:B 336 149 0.1126 0.1280 0.2886 8.28e-09 5b53:A, 5b55:A, 5b55:B, 5z5c:A, 5z5c:C, 5z5c:D
35 3pc3:A 504 202 0.1361 0.1032 0.2574 3.86e-08 3pc2:A, 3pc4:A
36 6xwl:C 477 310 0.2120 0.1698 0.2613 9.51e-08 6xwl:F, 6xwl:A, 6xwl:B, 6xwl:D, 6xwl:E, 6xyl:A, 6xyl:B, 6xyl:C, 6xyl:D, 6xyl:E, 6xyl:F, 6y21:D, 6y21:A, 6y21:B, 6z3s:D, 6z3s:A, 6z3s:B, 6zs7:D, 6zs7:A, 6zs7:B, 6zs7:C, 6zs7:E, 6zs7:F
37 5ohx:A 488 310 0.2016 0.1578 0.2484 6.16e-07 5ohx:B
38 5dbh:X 312 296 0.2094 0.2564 0.2703 1.26e-06 6aif:A, 5dbe:X, 7djq:A, 3iqg:X, 3iqh:X, 3iqi:X, 4li3:X, 4nu8:X, 4ore:X, 1y7l:A, 7yod:A, 7yoh:A, 7yoi:A, 7yol:A, 7yom:A, 4zu1:X, 4zu6:X
39 8y1j:A 502 300 0.1963 0.1494 0.2500 7.71e-05 8y1j:B
40 7jmq:B 396 151 0.1047 0.1010 0.2649 1.19e-04 1a50:B, 1a5a:B, 1a5b:B, 1a5s:B, 8b03:B, 8b05:B, 8b06:B, 8b08:B, 1beu:B, 1bks:B, 5bw6:B, 1c29:B, 6c73:B, 1c8v:B, 1c9d:B, 3cep:B, 5cgq:B, 2cle:B, 2clf:B, 2clh:B, 2cli:B, 2clk:B, 2cll:B, 2clm:B, 2clo:B, 1cw2:B, 1cx9:B, 6d0v:B, 2dh5:A, 6duc:B, 6dz4:B, 6dzo:B, 1fuy:B, 4hn4:B, 4hpj:B, 4hpx:B, 4ht3:B, 2j9x:B, 2j9y:B, 2j9z:B, 7jhw:B, 7jll:B, 7jqw:B, 7jtt:B, 7k0b:B, 1k3u:B, 7k5a:B, 1k7e:B, 1k7f:B, 1k7x:B, 1k8x:B, 1k8y:B, 1k8z:B, 7ka1:B, 7kbn:B, 1kfb:B, 1kfc:B, 1kfe:B, 1kfj:B, 1kfk:B, 7kh6:B, 7ki7:B, 4kkx:B, 7kmc:B, 7kq9:B, 7kqf:B, 7ku9:B, 7kwv:B, 7kxc:B, 7kyt:B, 7l03:B, 7l1h:B, 7l47:B, 7l4d:B, 7l5h:B, 7lev:B, 7lgx:B, 7lkl:B, 7lpf:B, 7lt4:B, 7ltp:B, 7lut:B, 7lv5:B, 7lvx:B, 7lx1:B, 7ly8:B, 7m2l:B, 7m3s:B, 7me8:B, 7mt4:B, 7mt5:B, 7mt6:B, 6o1h:B, 3pr2:B, 1qop:B, 1qoq:B, 2rh9:B, 1tjp:B, 2trs:B, 2tsy:B, 1ttp:B, 1ttq:B, 2tys:B, 1ubs:B, 6vfd:B, 6vnt:B, 1wbj:B, 6wdu:B, 2wsy:B, 4wx2:B, 6wx3:B, 6x0c:B, 6xe3:B, 6xin:B, 6xnc:B, 6xoy:B, 6xrh:B, 6xsy:B, 6xt0:B, 4xug:B, 4y6g:B, 4zqc:B
41 5tci:H 406 223 0.1518 0.1429 0.2601 4.88e-04 6dwe:B, 6dwe:H, 6dwe:F, 6dwe:D, 6e9p:B, 6e9p:D, 6e9p:F, 6e9p:H, 5ocw:B, 5ocw:D, 5ocw:F, 5ocw:H, 5ocw:J, 5ocw:L, 5ocw:N, 5ocw:P, 5ocw:R, 5ocw:T, 5ocw:V, 5ocw:X, 5tcg:B, 5tcg:H, 5tcg:F, 5tcg:D, 5tci:B, 5tci:F, 5tci:D, 5tcj:B, 5tcj:H, 5tcj:F, 5tcj:D, 6u6c:B, 6u6c:D, 6u6c:F, 6u6c:H, 6uap:B, 6uap:D, 6uap:F, 6uap:H, 6ub9:B, 6ub9:D, 6ub9:F, 6ub9:H, 6usa:B, 6usa:D, 6usa:F, 6usa:H
42 5ey5:B 383 144 0.1021 0.1018 0.2708 0.002 5ey5:D
43 5kzm:B 395 151 0.1021 0.0987 0.2583 0.003
44 2c2g:A 448 51 0.0576 0.0491 0.4314 0.044 2c2b:A, 2c2b:B, 2c2b:C, 2c2b:D, 2c2b:E, 2c2b:F, 2c2g:B
45 2rhg:B 364 102 0.0681 0.0714 0.2549 0.085
46 8vhh:A 389 129 0.0916 0.0900 0.2713 0.13 8egy:A, 8egy:B, 8egz:A, 8egz:B, 8eh0:A, 8eh0:B, 8eh1:A, 8eh1:B, 8vhh:B
47 6nmx:A 350 295 0.1728 0.1886 0.2237 0.16 6cgq:A, 6cgq:B, 6nmx:B, 6nmx:C, 6nmx:D
48 5i0x:B 158 103 0.0838 0.2025 0.3107 0.19 5i0x:A, 5i0y:A, 5i0y:B, 3nrq:A, 3nrq:B
49 4qys:B 418 157 0.0916 0.0837 0.2229 0.28 6hte:B, 6hte:D, 4qys:A
50 5ixj:D 394 142 0.0916 0.0888 0.2465 0.37 6am8:A, 6am8:B, 6am8:C, 6am8:D, 6am9:A, 6am9:B, 6am9:C, 6am9:D, 6amh:A, 6amh:B, 6amh:C, 6amh:D, 6ami:A, 6ami:B, 6ami:C, 6ami:D, 6cut:A, 6cut:B, 6cut:C, 6cut:D, 6cuz:A, 6cuz:D, 5dw0:A, 5dw0:B, 5dw0:C, 5dw0:D, 5dw3:A, 5dw3:B, 5dw3:C, 5dw3:D, 5ixj:A, 5ixj:B, 5ixj:C, 7rnp:A, 7rnp:B, 7rof:A, 7rof:D, 5t6m:A, 5t6m:B, 5t6m:C, 5t6m:D, 1v8z:A, 1v8z:B, 1v8z:C, 1v8z:D, 5vm5:A, 5vm5:B, 5vm5:C, 5vm5:D, 1wdw:B, 1wdw:D, 1wdw:F, 1wdw:H, 1wdw:J, 1wdw:L
51 3k7y:A 405 53 0.0419 0.0395 0.3019 1.6
52 6w2j:B 1364 100 0.0759 0.0213 0.2900 2.4
53 6uel:A 1333 100 0.0759 0.0218 0.2900 2.4 6uel:B
54 5dou:D 1430 100 0.0759 0.0203 0.2900 2.5 5dou:A, 5dou:B, 5dou:C, 6w2j:A
55 4d9n:A 391 178 0.1047 0.1023 0.2247 2.6 4d9m:A, 4d9m:B, 4d9n:B
56 2ihm:B 336 34 0.0340 0.0387 0.3824 3.0 2ihm:A
57 2i54:A 242 97 0.0707 0.1116 0.2784 3.1 2i54:B, 2i54:C, 2i55:A, 2i55:B, 2i55:C
58 7uzf:C 602 64 0.0576 0.0365 0.3438 4.0 9b8p:A, 9brd:A, 7khr:C, 7u4t:B, 7u8p:C, 7u8q:B, 7u8r:A, 7unf:M, 7uzg:C, 7uzh:B, 7uzi:B, 7uzj:C, 7uzk:C, 6vq6:C, 6vq7:B, 6vq8:A, 6vq9:C, 6vqa:B, 6vqb:A, 6wlz:C, 6wm2:C, 6wm3:B, 6wm4:A, 6xbw:C, 6xby:A
59 5n0s:B 404 88 0.0628 0.0594 0.2727 5.6 6gew:A, 5n0n:A, 5n0o:A, 5n0o:B, 5n0p:A, 5n0p:B, 5n0q:A, 5n0q:B, 5n0r:A, 5n0s:A, 5n0t:A, 5n0t:B, 5n0u:A, 5n0v:A, 5n0v:B, 5n0w:A, 5n0w:B, 5n0x:A, 5n0x:B, 5n4i:A, 5ouf:A, 6qzy:A, 6qzz:A, 6qzz:B, 6r00:A, 6tsc:A
60 2kaw:A 90 38 0.0366 0.1556 0.3684 6.6 6lcb:A, 2mx6:A
61 1l6o:A 95 38 0.0366 0.1474 0.3684 6.9 2f0a:B, 2f0a:D, 1l6o:B, 1l6o:C, 6zbq:B, 6zbz:A, 6zbz:B, 6zbz:C, 6zbz:D, 6zc3:A, 6zc3:B, 6zc4:B, 6zc6:A, 6zc7:A, 6zc7:B, 6zc8:A, 6zc8:B
62 6ks6:Q 548 86 0.0576 0.0401 0.2558 7.0 6ks6:q, 4v81:H, 4v81:P, 4v81:h, 4v81:p, 4v8r:AQ, 4v8r:Aq, 4v8r:BQ, 4v8r:Bq, 4v94:H, 4v94:P, 4v94:h, 4v94:p, 7ylw:Q, 7ylw:q, 7ylx:Q, 7ylx:q, 7yly:Q, 7yly:q
63 4c9i:F 162 83 0.0471 0.1111 0.2169 9.7
64 6zbq:A 89 45 0.0393 0.1685 0.3333 9.7 6zc4:A
65 5xgu:A 631 42 0.0366 0.0222 0.3333 10.0 5xgu:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218