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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ADLANGAKVFSGNCAACHMGGGNVVMANKTLKKEALEQFGMYSEDAIIYQVQHGKNAMPAFAGRLTDEQIQDVAAYVLDQ
AAKGWV

The query sequence (length=86) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1c6s:A 87 85 0.9884 0.9770 1.0000 1.26e-59 6tr1:A, 6tr1:C, 6tr1:E, 6tsy:A, 6tsy:B, 6tsy:C, 6tsy:D, 6tsy:E, 6tsy:F
2 1gdv:A 85 85 0.6628 0.6706 0.6706 5.52e-38
3 3ph2:B 85 85 0.7209 0.7294 0.7294 8.94e-38 2v08:A, 2v08:B
4 4gyd:A 86 85 0.6628 0.6628 0.6706 1.03e-36 4gyd:B, 4gyd:C, 4gyd:D, 4gyd:E, 4gyd:F, 4h0j:A, 4h0j:B, 4h0j:C, 4h0j:D, 4h0j:E, 4h0j:F, 4h0k:A, 4h0k:B
5 7y5e:GN 84 84 0.5930 0.6071 0.6071 1.31e-33 7y5e:G2, 7y7a:G7, 7y7a:Go
6 1kib:A 89 88 0.6279 0.6067 0.6136 6.34e-33 1f1f:A, 1kib:B, 1kib:C, 1kib:D, 1kib:E, 1kib:F, 1kib:G, 1kib:H
7 2zbo:A 86 85 0.5698 0.5698 0.5765 7.02e-33 2zbo:C, 2zbo:E, 2zbo:G, 2zbo:I, 2zbo:K
8 3dmi:A 87 86 0.5930 0.5862 0.5930 1.55e-31
9 1cyj:A 90 83 0.6163 0.5889 0.6386 5.91e-31 1cyi:A
10 1a2s:A 89 84 0.5814 0.5618 0.5952 8.68e-29 1ced:A, 1ctj:A
11 1ls9:A 91 81 0.5465 0.5165 0.5802 7.78e-28
12 1c6o:A 89 84 0.5465 0.5281 0.5595 7.10e-27 1c6o:B, 1c6r:A
13 3dr0:A 93 76 0.4884 0.4516 0.5526 1.14e-21 3dr0:B, 3dr0:C, 4eic:A, 4eid:A
14 4eie:A 82 80 0.4070 0.4268 0.4375 3.32e-19 4eif:A
15 2dge:A 102 96 0.3837 0.3235 0.3438 2.60e-13 2ce0:A, 2ce1:A, 2dge:C, 2dge:B, 2dge:D, 2v07:A
16 4kmg:A 88 81 0.3256 0.3182 0.3457 5.42e-12
17 7o38:A 81 72 0.3140 0.3333 0.3750 3.15e-09
18 8hn3:A 80 78 0.3023 0.3250 0.3333 7.27e-07 8hn3:B
19 2zon:G 81 77 0.3140 0.3333 0.3506 1.65e-06
20 3dp5:A 99 58 0.2209 0.1919 0.3276 3.16e-06 3cu4:A, 5mcs:A, 6u97:A
21 6adq:C 223 88 0.3721 0.1435 0.3636 3.40e-05 6adq:O, 6hwh:M, 6hwh:K, 8ovc:O, 8ovc:C, 8ovd:O, 8ovd:C, 7rh5:O, 7rh5:I, 7rh6:O, 7rh6:I, 7rh7:O, 7rh7:I
22 6hwh:i 162 88 0.3721 0.1975 0.3636 3.73e-05 6hwh:j
23 4lji:A 133 97 0.3256 0.2105 0.2887 4.42e-05 4lji:B
24 5djq:C 303 79 0.3140 0.0891 0.3418 2.61e-04 5djq:M, 5djq:F, 5djq:I, 3mk7:C, 3mk7:M, 3mk7:F, 3mk7:I
25 5djq:C 303 73 0.2209 0.0627 0.2603 0.42 5djq:M, 5djq:F, 5djq:I, 3mk7:C, 3mk7:M, 3mk7:F, 3mk7:I
26 8snh:G 304 83 0.3140 0.0888 0.3253 2.82e-04
27 7e1w:O 223 84 0.3372 0.1300 0.3452 4.81e-04 7e1v:O, 7e1v:C, 7e1w:C, 7e1x:O, 7e1x:C, 8hcr:C, 8hcr:O
28 7o9u:A 153 83 0.2326 0.1307 0.2410 7.45e-04
29 1yiq:A 684 85 0.3023 0.0380 0.3059 0.001
30 8gy3:A 440 85 0.3256 0.0636 0.3294 0.001
31 7vzg:C 193 77 0.2791 0.1244 0.3117 0.004 7vzr:C
32 7qhm:C 233 80 0.2674 0.0987 0.2875 0.006 7q21:C, 7q21:c, 7qhm:P, 7qho:C, 7qho:P
33 8smr:G 312 76 0.2442 0.0673 0.2763 0.007
34 8smr:G 312 81 0.3023 0.0833 0.3210 0.015
35 8gy2:B 433 95 0.3023 0.0600 0.2737 0.020
36 3oa8:B 180 83 0.3256 0.1556 0.3373 0.024 3oa8:D, 3oa8:F, 3ocd:B, 3ocd:D
37 6jlu:V 137 52 0.2093 0.1314 0.3462 0.024 8iwh:V, 8iwh:v, 6j3y:V, 6j3y:v, 6j3z:V, 6j3z:v, 6j40:V, 6j40:v, 8j5k:V, 8j5k:v, 6jlu:v, 7vd5:V, 7vd5:v
38 4j20:A 88 86 0.2907 0.2841 0.2907 0.042 4j20:B
39 6xkw:p 254 78 0.3372 0.1142 0.3718 0.043 6xkx:p, 6xkz:p
40 6xkw:p 254 77 0.2907 0.0984 0.3247 0.41 6xkx:p, 6xkz:p
41 4yuu:V1 129 34 0.1395 0.0930 0.3529 0.045 4yuu:v1, 4yuu:V2, 4yuu:v2
42 2yk3:A 110 97 0.3140 0.2455 0.2784 0.081 2yk3:B, 2yk3:C
43 4dy9:A 108 97 0.3023 0.2407 0.2680 0.092 4ged:B
44 7w2j:C 418 99 0.3372 0.0694 0.2929 0.098 8jej:C, 8jek:C, 8k6j:C, 8k6k:C, 7w2j:F, 7wsq:C, 7wsq:F, 8xcm:C, 8xcn:C
45 7w2j:C 418 89 0.2791 0.0574 0.2697 0.33 8jej:C, 8jek:C, 8k6j:C, 8k6k:C, 7w2j:F, 7wsq:C, 7wsq:F, 8xcm:C, 8xcn:C
46 8xr6:V 137 52 0.1860 0.1168 0.3077 0.11 8wb4:V, 8wb4:v, 8xr6:v
47 2zzs:A 81 65 0.2674 0.2840 0.3538 0.12 2zzs:B, 2zzs:C, 2zzs:D, 2zzs:E, 2zzs:F, 2zzs:G, 2zzs:H, 2zzs:I, 2zzs:J, 2zzs:K, 2zzs:L, 2zzs:M, 2zzs:N, 2zzs:O, 2zzs:P, 2zzs:Q, 2zzs:R, 2zzs:S, 2zzs:T, 2zzs:U, 2zzs:V, 2zzs:W, 2zzs:X, 2zzs:Y, 2zzs:Z, 2zzs:1, 2zzs:2, 2zzs:3, 2zzs:4, 2zzs:5, 2zzs:6
48 1kx2:A 81 77 0.2674 0.2840 0.2987 0.12 1kx7:A
49 7vzg:c 145 66 0.2558 0.1517 0.3333 0.13 7vzr:c
50 7y5e:VL 134 34 0.1395 0.0896 0.3529 0.15 7y5e:V6, 7y5e:v6, 7y5e:vL, 7y7a:V9, 7y7a:v9, 7y7a:VE, 7y7a:vE, 7y7a:VO, 7y7a:vO, 7y7a:VZ, 7y7a:vZ, 7y7a:Vm, 7y7a:vm
51 6r6m:B 100 41 0.1395 0.1200 0.2927 0.22 6r6n:B, 6r6o:B
52 5mxy:A 83 77 0.2326 0.2410 0.2597 0.28 5mxz:A
53 6btm:E 161 78 0.2791 0.1491 0.3077 0.31
54 8hdd:B 121 82 0.2442 0.1736 0.2561 0.34
55 1cyc:A 103 98 0.3023 0.2524 0.2653 0.37 1cyc:B, 3cyt:O, 3cyt:I, 5cyt:R, 1i54:A, 1i54:B, 1i55:A, 1i55:B, 1lfm:A, 1lfm:B
56 1gks:A 78 66 0.2209 0.2436 0.2879 0.46
57 3a0b:V 137 31 0.1279 0.0803 0.3548 0.54 3a0b:v, 3a0h:V, 3a0h:v, 2axt:V, 2axt:v, 5b5e:V, 5b5e:v, 5b66:V, 5b66:v, 7cji:V, 7cji:v, 7cjj:V, 7cjj:v, 7cou:V, 7cou:v, 7d1t:V, 7d1t:v, 7d1u:V, 7d1u:v, 6dhe:V, 6dhe:v, 6dhf:V, 6dhf:v, 6dhg:V, 6dhg:v, 6dhh:V, 6dhh:v, 6dho:V, 6dho:v, 6dhp:V, 6dhp:v, 5e79:V, 5e79:v, 5e7c:V, 5e7c:v, 7eda:V, 9evx:V, 9evx:v, 8ez5:V, 8ez5:v, 8f4c:V, 8f4c:v, 8f4d:V, 8f4d:v, 8f4e:V, 8f4e:v, 8f4f:V, 8f4f:v, 8f4g:V, 8f4g:v, 8f4h:V, 8f4h:v, 8f4i:V, 8f4i:v, 8f4j:V, 8f4j:v, 8f4k:V, 8f4k:v, 4fby:V, 4fby:i, 8gn0:V, 8gn0:v, 8gn1:V, 8gn1:v, 8gn2:V, 8gn2:v, 5gth:V, 5gth:v, 5gti:V, 5gti:v, 5h2f:V, 5h2f:v, 4il6:V, 4il6:v, 8ir5:V, 8ir5:v, 8ir6:V, 8ir6:v, 8ir7:V, 8ir7:v, 8ir8:V, 8ir8:v, 8ir9:V, 8ir9:v, 8ira:V, 8ira:v, 8irb:V, 8irb:v, 8irc:V, 8irc:v, 8ird:V, 8ird:v, 8ire:V, 8ire:v, 8irf:V, 8irf:v, 8irg:V, 8irg:v, 8irh:V, 8irh:v, 8iri:V, 8iri:v, 4ixq:V, 4ixq:v, 4ixr:V, 4ixr:v, 1izl:V, 1izl:0, 6jlj:V, 6jlj:v, 6jlk:V, 6jlk:v, 6jll:V, 6jll:v, 6jlm:V, 6jlm:v, 6jln:V, 6jln:v, 6jlo:V, 6jlo:v, 6jlp:V, 6jlp:v, 5kaf:V, 5kaf:v, 5kai:V, 5kai:v, 3kzi:V, 5mx2:V, 5mx2:v, 1mz4:A, 4pbu:V, 4pbu:v, 4pj0:V, 4pj0:v, 7rf1:V, 7rf1:v, 7rf2:V, 7rf2:v, 7rf3:V, 7rf3:v, 7rf4:V, 7rf4:v, 7rf5:V, 7rf5:v, 7rf6:V, 7rf6:v, 7rf7:V, 7rf7:v, 7rf8:V, 7rf8:v, 4rvy:V, 4rvy:v, 1s5l:V, 1s5l:v, 5tis:V, 5tis:v, 4tnh:V, 4tnh:v, 4tni:V, 4tni:v, 4tnj:V, 4tnj:v, 4tnk:V, 4tnk:v, 4ub6:V, 4ub6:v, 4ub8:V, 4ub8:v, 5v2c:V, 5v2c:v, 4v62:AV, 4v62:BV, 4v82:AV, 4v82:BV, 6w1o:V, 6w1o:v, 6w1p:V, 6w1p:v, 6w1q:V, 6w1q:v, 6w1r:V, 6w1r:v, 6w1t:V, 6w1t:v, 6w1u:V, 6w1u:v, 6w1v:V, 6w1v:v, 1w5c:T, 1w5c:V, 5ws5:V, 5ws5:v, 5ws6:V, 5ws6:v, 3wu2:V, 3wu2:v, 7yq2:V, 7yq2:v, 7yq7:V, 7yq7:v, 5zzn:V, 5zzn:v
58 8cmo:9 184 24 0.1395 0.0652 0.5000 0.65
59 2zoo:A 438 84 0.2674 0.0525 0.2738 0.67
60 8yts:A 83 84 0.2791 0.2892 0.2857 0.69 8yts:B
61 1e29:A 135 29 0.1163 0.0741 0.3448 0.77 7n8o:V, 7n8o:v, 7rcv:V, 7rcv:v, 8tow:V, 8tow:v
62 8eqm:V 131 35 0.1395 0.0916 0.3429 0.80 8eqm:v
63 2xts:D 204 17 0.1047 0.0441 0.5294 1.1 2xts:B
64 8t4j:A 552 22 0.1395 0.0217 0.5455 1.4 1jj7:A, 8t4e:A, 8t4f:A, 8t4g:A, 8t4h:A, 8t4i:A
65 4ax3:D 457 87 0.2442 0.0460 0.2414 1.4 4ax3:A, 4ax3:B, 4ax3:C, 6f1q:A, 6fja:A, 5obo:A, 5ocb:A, 5ocf:A, 8qgf:A, 6qpt:A, 6qpt:B, 6qpt:C, 6qpt:D, 6qpt:E, 6qpt:F, 6qpu:A, 6qpu:B, 6qpu:C, 6qpu:D, 6qpu:E, 6qpu:F, 6qpv:A, 6qpv:I, 6qpx:A, 6qpx:I, 6qpz:A, 6qpz:I, 6qq0:A, 6qq1:A, 6qq2:A, 7qq2:A, 7r2u:A, 2yqb:A, 3zbm:A, 3ziy:A
66 8wql:VD 135 56 0.1977 0.1259 0.3036 1.6 1f1c:A, 1f1c:B, 8wql:VE, 8wql:V1, 8wql:v1, 8wql:vD, 8wql:vE
67 8jjr:K 154 38 0.1395 0.0779 0.3158 2.1
68 2yev:B 319 13 0.1047 0.0282 0.6923 2.2 2yev:E
69 4pwa:D 87 87 0.3256 0.3218 0.3218 2.3 4pw9:B, 4pwa:A, 4pwa:B, 4pwa:C
70 1kv9:A 664 78 0.2093 0.0271 0.2308 2.4
71 8smr:K 181 70 0.2209 0.1050 0.2714 2.6 6q2u:A, 8smr:N, 8snh:K, 8snh:N
72 6up7:R 322 40 0.1512 0.0404 0.3250 2.8 8jpb:R, 8jpc:R, 8jpf:R, 6os9:R, 6osa:R
73 7eih:A 588 32 0.1628 0.0238 0.4375 3.1 7eih:B, 7eii:A, 7eii:B, 7eij:A, 7eij:B
74 8uf3:A 187 86 0.3023 0.1390 0.3023 3.3 8uf3:B
75 5lo9:A 471 81 0.2558 0.0467 0.2716 3.8 5lo9:B
76 6a0t:B 332 39 0.1395 0.0361 0.3077 4.0 6a0s:B, 6a0s:A, 6a0t:A, 6a0u:B, 6a0u:A, 2ejw:A, 2ejw:B, 2ejw:E, 2ejw:F, 5xdf:A, 5xdf:B
77 3m97:X 118 23 0.1628 0.1186 0.6087 5.1 1c7m:A, 1i6d:A, 1i6e:A, 1ql3:A, 1ql3:B, 1ql3:C, 1ql3:D, 1ql4:A, 1ql4:B, 1ql4:C, 1ql4:D
78 1n83:A 251 78 0.2326 0.0797 0.2564 5.2 1s0x:A, 4s15:A, 4s15:B
79 3nvl:A 549 51 0.1744 0.0273 0.2941 5.6 3nvl:B
80 7ak5:O 320 56 0.1977 0.0531 0.3036 6.1 7ak6:O, 7b93:O, 8c2s:O, 8ca3:O, 8ca5:O, 6g2j:O, 6g72:O, 8iao:O, 8iaq:O, 8ib4:O, 8ib6:O, 8ib9:O, 8ibb:O, 8ibd:O, 8ibf:O, 8ic2:O, 8ic4:O, 8olt:O, 8om1:O, 7psa:O, 8pw5:O1, 8pw6:O1, 8pw7:O1, 8rgp:O, 8rgq:O, 8rgr:O, 8rgt:O, 6zr2:O, 6ztq:O
81 5upx:A 380 84 0.2558 0.0579 0.2619 6.4
82 1akk:A 104 18 0.0930 0.0769 0.4444 6.9 2b4z:A, 5c0z:A, 5c0z:D, 5c0z:B, 5c0z:C, 5c9m:A, 5c9m:D, 5c9m:B, 5c9m:C, 1crc:A, 1crc:B, 5df5:A, 5df5:B, 5df5:C, 5df5:D, 8dvx:A, 8dvx:D, 8dvx:B, 8dvx:C, 8dzl:A, 8dzl:B, 8dzl:C, 8dzl:D, 6ff5:A, 1fi7:A, 1fi9:A, 2frc:A, 1giw:A, 2giw:A, 1hrc:A, 1i5t:A, 5iy5:1, 5iy5:2, 3j2t:H, 3j2t:I, 3j2t:J, 3j2t:K, 3j2t:L, 3j2t:M, 3j2t:N, 3jbt:B, 3jbt:D, 3jbt:F, 3jbt:H, 3jbt:J, 3jbt:L, 3jbt:N, 5juy:H, 5juy:I, 5juy:J, 5juy:K, 5juy:L, 5juy:M, 5juy:N, 6k9i:A, 6k9j:A, 1lc1:A, 1lc2:A, 7ljx:A, 7ljx:B, 1m60:A, 6n1o:A, 6n1o:B, 6n1o:C, 6n1o:D, 2n3b:A, 3nbs:A, 3nbs:B, 3nbs:C, 3nbs:D, 3nbt:A, 3nbt:E, 3nbt:B, 3nbt:C, 3nbt:D, 3nbt:F, 4nfg:B, 3o1y:A, 3o1y:B, 3o1y:C, 3o20:A, 3o20:B, 3o20:C, 1ocd:A, 2pcb:B, 4rsz:A, 4rsz:B, 4rsz:C, 4rsz:D, 4rsz:E, 4rsz:F, 6suv:AaA, 6suv:BaB, 6suv:CaC, 6suv:DaD, 6suv:EaE, 6suv:FaF, 6suv:GaG, 6suv:HaH, 1u75:B, 3wc8:A, 1wej:F, 3wui:A, 5wve:B, 5wve:D, 5wve:F, 5wve:H, 5wve:J, 5wve:L, 5wve:N, 2ybb:Y, 5zkv:A
83 9av7:A 304 24 0.1163 0.0329 0.4167 6.9
84 8k9e:E 164 94 0.2907 0.1524 0.2660 7.9 8k9f:E, 8x2j:E
85 5u7w:A 404 33 0.1512 0.0322 0.3939 8.9 5u7v:A
86 8j5k:5 169 25 0.1163 0.0592 0.4000 9.5 8j5k:0, 8w4o:5

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218