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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AAYQVLIVGAGFSGAETAFWLAQKGVRVGLLTQSLDAVMMPFLPPKPPFPPGSLLERAYDPKDERVWAFHARAKYLLEGL
RPLHLFQATATGLLLEGNRVVGVRTWEGPPARGEKVVLAVGSFLGARLFLGGVVEEAGRLSEASYPDLLEDLSRLGFRFV
EREGEVPPGYRVRYLAFHPEEWEEKTFRLKRLEGLYAVGLCVREGDYARMSEEGKRLAEHLLHEL

The query sequence (length=225) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2cul:A 225 225 1.0000 1.0000 1.0000 1.14e-160
2 3cp8:A 611 207 0.2222 0.0818 0.2415 4.79e-06 3cp8:B, 3cp8:C, 3cp8:D
3 2zxi:B 606 104 0.1244 0.0462 0.2692 8.22e-06 2zxh:A, 2zxh:B, 2zxi:A, 2zxi:C, 2zxi:D
4 3atq:A 452 86 0.1200 0.0597 0.3140 0.013 3atr:A, 4opc:A, 4opd:A, 4opd:B, 4opg:A, 4opi:A, 4opl:A, 4opt:A, 4opu:A
5 2bi7:A 383 30 0.0711 0.0418 0.5333 0.062 2bi8:A, 3gf4:A, 3gf4:B, 3inr:A, 3inr:B, 3int:A, 3int:B, 3kyb:A, 3kyb:B, 1wam:A
6 7f8d:A 313 21 0.0578 0.0415 0.6190 0.075 7by9:A, 7by9:B, 7by9:C, 7by9:D, 7bya:A, 7bya:B, 7bya:C, 7bya:D, 7f8d:B, 7f8d:C, 7f8d:D, 7x1l:A, 7x1l:B, 7x1l:E, 7x1l:F, 7x1l:C, 7x1l:D
7 1zov:A 381 102 0.1467 0.0866 0.3235 0.13 1zov:B
8 3ihg:A 535 25 0.0667 0.0280 0.6000 0.20 3ihg:B, 3ihg:C
9 8eg3:A 554 65 0.0889 0.0361 0.3077 0.41 1p49:A
10 8bdb:L 138 50 0.0667 0.1087 0.3000 0.48 8bdb:N
11 1uxg:A 308 21 0.0533 0.0390 0.5714 0.74 1guy:A, 1guy:C, 1ur5:A, 1ur5:C, 1uxg:B, 1uxh:A, 1uxh:B, 1uxi:A, 1uxi:B, 1uxj:A, 1uxj:C, 1uxk:A, 1uxk:C
12 6pxs:A 370 31 0.0622 0.0378 0.4516 0.90 6pxs:B, 6pxs:C, 6pxs:D
13 6kgy:B 441 32 0.0667 0.0340 0.4688 0.99 6kgy:A, 6kgy:C, 6kgy:D, 6kod:A, 6kod:B, 6kod:C, 6kod:D, 6kyy:A, 6kyy:B, 6kyy:C, 6kyy:D
14 6eri:BM 111 56 0.0844 0.1712 0.3393 1.2 5mmj:m, 5mmm:m
15 7d6v:A 601 34 0.0533 0.0200 0.3529 1.2 7d6x:A
16 3fg2:P 404 118 0.1556 0.0866 0.2966 1.2
17 4gdp:B 502 38 0.0622 0.0279 0.3684 1.6 3bi2:A, 3bi2:B, 3bi4:A, 3bi4:B, 3bi5:A, 3bi5:B, 3bnm:B, 3bnm:A, 3bnu:B, 3bnu:A, 3cn8:B, 3cn8:A, 3cnd:B, 3cnd:A, 3cnp:B, 3cnp:A, 3cns:A, 3cns:B, 3cnt:B, 3cnt:A, 4ech:A, 4ech:B, 4gdp:A, 4gdp:C, 4gdp:D, 1rsg:B, 1xpq:A, 1xpq:B, 1xpq:C, 1xpq:D, 1yy5:A, 1yy5:B, 1z6l:A, 1z6l:B
18 1rsg:A 481 38 0.0622 0.0291 0.3684 1.6
19 8k40:A 448 70 0.0889 0.0446 0.2857 1.6 8k40:B, 8k41:A
20 8pxv:B 634 115 0.1244 0.0442 0.2435 1.7 8pxv:C
21 7exs:A 372 29 0.0667 0.0403 0.5172 1.9
22 3nyc:A 381 20 0.0444 0.0262 0.5000 2.3 3nye:A, 3nyf:A, 6p9d:A, 6pld:A, 7rdf:A, 3sm8:A
23 6bza:C 501 32 0.0578 0.0259 0.4062 2.4 6bza:A, 6bza:B, 6bzn:D, 6bzq:A, 6bzq:B, 6bzq:C, 6bzq:D, 6bzt:A, 6bzt:B, 6bzt:C, 6bzt:D, 6bzz:A, 6bzz:B, 6bzz:C, 6bzz:D
24 5ub4:B 279 65 0.0889 0.0717 0.3077 2.6 5ub4:A, 5ub6:A, 5ub6:B, 5ub7:A, 5ub7:B
25 5dbj:E 437 33 0.0533 0.0275 0.3636 3.2 5dbj:A, 5dbj:B, 5dbj:C, 5dbj:D
26 8x38:A 430 28 0.0578 0.0302 0.4643 3.5
27 1h3e:A 427 119 0.1556 0.0820 0.2941 3.6
28 7v0b:A 539 29 0.0578 0.0241 0.4483 3.8 7v0b:B, 7v0b:C, 7v0b:D
29 2fja:A 642 35 0.0578 0.0202 0.3714 4.6 2fja:C, 2fjb:A, 2fjb:C, 2fjd:A, 2fjd:C, 2fje:A, 2fje:C, 1jnr:A, 1jnr:C, 1jnz:A, 1jnz:C
30 8gix:E 991 39 0.0622 0.0141 0.3590 4.7
31 2gb0:B 389 51 0.0756 0.0437 0.3333 5.2 2a89:A, 2a89:B, 3bhf:A, 3bhf:B, 3bhk:A, 3bhk:B, 1el5:A, 1el5:B, 1el7:A, 1el7:B, 1el8:A, 1el8:B, 1el9:A, 1el9:B, 1eli:A, 1eli:B, 2gb0:A, 2gf3:A, 2gf3:B, 1l9c:A, 1l9c:B, 1l9d:A, 1l9d:B, 1l9e:A, 1l9e:B, 3m0o:A, 3m0o:B, 3m12:A, 3m12:B, 3m13:A, 3m13:B, 3m13:C, 3m13:D, 3qse:A, 3qse:B, 3qsm:A, 3qsm:B, 3qss:A, 3qss:B
32 1vko:A 511 95 0.0978 0.0431 0.2316 5.4
33 7cyx:A 363 31 0.0489 0.0303 0.3548 6.1 7cyx:B
34 6aix:A 358 119 0.1600 0.1006 0.3025 6.4 6aiy:A, 3fqi:A, 3fqj:A, 4j7l:A, 4j7m:A, 4j7n:A, 5uli:A, 6wre:A, 6wuf:A, 6wuk:A
35 7mjy:A 448 26 0.0356 0.0179 0.3077 6.5 7mjv:A, 7mjw:A, 7mjw:B, 7mjx:B, 7mjx:A, 7mjz:A
36 8uiu:A 412 148 0.1644 0.0898 0.2500 6.5 8uiu:C, 8uiu:B, 8urc:A, 8urc:C, 8urc:B, 8urd:A, 8urd:B, 8urd:C
37 2iag:A 471 23 0.0533 0.0255 0.5217 6.7 3b6h:A, 3b6h:B, 2iag:B
38 7fgp:A 379 28 0.0533 0.0317 0.4286 7.3 7fgp:B
39 7ouj:AAA 540 27 0.0622 0.0259 0.5185 8.0
40 2ehd:B 213 175 0.2356 0.2488 0.3029 8.1 2ehd:A
41 1ldb:A 294 66 0.0756 0.0578 0.2576 8.1
42 1guz:A 305 21 0.0489 0.0361 0.5238 8.5 1guz:B, 1guz:C, 1guz:D
43 1gv0:A 301 21 0.0489 0.0365 0.5238 9.1 1gv0:B
44 4cy8:A 539 33 0.0667 0.0278 0.4545 9.2 4cy8:B, 4cy8:C, 4cy8:D
45 8fhj:C 532 37 0.0667 0.0282 0.4054 9.3 8fhj:A, 8fhj:B
46 3he3:A 366 29 0.0622 0.0383 0.4828 9.6 3hdq:A, 3hdq:B, 3hdq:C, 3hdq:D, 3hdq:E, 3hdq:F, 3hdq:G, 3hdq:H, 3hdq:I, 3hdq:J, 3hdy:A, 3hdy:B, 3hdy:C, 3hdy:D, 3hdy:E, 3hdy:F, 3hdy:G, 3hdy:H, 3hdy:I, 3hdy:J, 3he3:B, 3he3:C, 3he3:D, 3he3:E, 3he3:F, 3he3:G, 3he3:H, 3he3:I, 3he3:J, 3mj4:A, 3mj4:B, 3mj4:C, 3mj4:D, 3mj4:E, 3mj4:F, 3mj4:G, 3mj4:H, 3mj4:I, 3mj4:J

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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