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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AAPTLYIFPHAGGTAKDYVAFSREFSADVKRIAVQYPGQHPLESIPTLADEIFAMMKPSARIDDPVAFFGHSMGGMLAFE
VALRYQSAGHRVLAFFVSACSAPGHIRYKQLQDLSDREMLDLFTRMTGMNPDFFTDDEFFVGLPTLRAVRAIAGYSCPPE
TKLSCPIYAFIGDKDWIATQDDMDPWRDRTTEEFSIRVFPGDHFYLNDNLPELVSDIEDKTLQW

The query sequence (length=224) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6fw5:A 233 230 0.9955 0.9571 0.9696 4.56e-164 6fvj:D, 6fvj:E, 6fw5:B, 6fw5:D
2 6fvj:B 212 225 0.9286 0.9811 0.9244 2.51e-148 6fvj:A, 6fvj:C, 6fvj:F, 6fvj:G, 6fvj:H, 6fw5:C
3 6ecd:A 245 215 0.2232 0.2041 0.2326 1.06e-04 6ece:B
4 2h7y:A 280 233 0.2366 0.1893 0.2275 0.002 9cgl:A, 9cgl:B, 9cgn:A, 9cgn:B, 2h7x:A, 2h7x:B, 2h7y:B, 2hfj:A, 2hfk:A, 2hfk:B
5 4zxh:A 1314 128 0.1429 0.0244 0.2500 0.006 4zxi:A
6 6n8e:A 1332 233 0.2143 0.0360 0.2060 0.016
7 6ecf:D 265 93 0.1161 0.0981 0.2796 0.061 6ece:A, 6ecf:A, 6ecf:B, 6ecf:C, 6ecf:E, 6ecf:F
8 5d3k:A 269 151 0.1741 0.1450 0.2583 0.29 5d3z:A
9 5ja2:A 1238 89 0.1071 0.0194 0.2697 0.47 5ja1:A, 5t3d:A
10 6eb3:B 268 36 0.0759 0.0634 0.4722 0.55 6eb3:A, 6eb3:C, 6eb3:D
11 5olu:A 310 192 0.2054 0.1484 0.2396 1.0
12 3i6y:A 278 63 0.0848 0.0683 0.3016 1.2 3i6y:B, 3s8y:A
13 6sl1:A 2652 56 0.0893 0.0075 0.3571 1.3 6sky:A, 6sky:B
14 6skz:A 2638 56 0.0893 0.0076 0.3571 1.3 6sl0:A, 6sl0:B
15 4mhl:A 161 45 0.0670 0.0932 0.3333 3.3
16 2wjs:A 519 93 0.1116 0.0482 0.2688 6.2
17 8hgw:A 288 38 0.0670 0.0521 0.3947 7.5 8hgw:B, 8hgw:C, 8hgw:D
18 2vsq:A 1273 30 0.0536 0.0094 0.4000 7.5
19 3uar:A 203 42 0.0670 0.0739 0.3571 7.7
20 6khm:K 312 39 0.0625 0.0449 0.3590 8.2 6khl:A, 6khl:B, 6khm:A, 6khm:B, 6khm:C, 6khm:D, 6khm:E, 6khm:F, 6khm:G, 6khm:H, 6khm:I, 6khm:J, 6khm:L, 6khm:M, 6khm:N, 6khm:O, 6khm:P, 6khm:Q, 6khm:R, 6khm:S, 6khm:T, 6khm:U, 6khm:V, 6khm:X, 6khm:Y, 6khm:W, 6khm:Z
21 1y7i:B 262 37 0.0625 0.0534 0.3784 8.2 1xkl:A, 1xkl:B, 1xkl:C, 1xkl:D, 1y7i:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218