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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPGGIVEKEAAIQVSNVAIFNAATGKADRVGFR
FEDGKKVRFFKSNSETI

The query sequence (length=97) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7ac7:U 103 102 1.0000 0.9417 0.9510 2.41e-61 8a3l:t, 7abz:U, 7acj:U, 7acr:U, 5ady:U, 5afi:U, 5aka:U, 8akn:t, 8am9:t, 8ana:t, 8ap4:t, 9ax7:t, 9ax8:U, 8aye:t, 8b0x:t, 7b5k:U, 8b7y:c, 3bbx:U, 8bf7:R, 8bge:R, 8bgh:R, 8bh4:R, 8bhj:R, 8bhl:R, 8bhn:R, 8bhp:R, 8bil:R, 8bim:R, 7bl2:U, 7bl3:U, 7bl4:U, 7bl5:U, 7bl6:U, 6bu8:23, 7bv8:V, 6by1:CU, 6by1:DU, 6c4i:V, 8c8x:U, 8c8y:U, 8c8z:U, 8c90:U, 8c91:U, 8c92:U, 8c93:U, 8c94:U, 8c95:U, 8c96:U, 8c97:U, 8c98:U, 8c99:U, 8c9a:U, 8c9b:U, 8c9c:U, 8cam:t, 8ceu:t, 8cgd:t, 8cgk:t, 8cgv:t, 9cg5:t, 9cg6:t, 9cg7:t, 9cl9:U, 7cpj:U, 4csu:U, 7d6z:U, 7d80:s, 6dnc:Y, 8eiu:t, 8ekc:W, 8emm:t, 6enf:U, 6enj:U, 6enu:U, 9fbv:t, 8fiz:DB, 8fto:t, 8fzd:W, 8fze:W, 8fzf:W, 8fzg:W, 8fzh:W, 8fzi:W, 8fzj:W, 8g2u:U, 8g31:U, 8g34:U, 8g38:U, 8g6w:t, 8g6x:t, 8g6y:t, 8g7p:W, 8g7q:W, 8g7r:W, 8g7s:W, 5gad:V, 5gae:V, 5gaf:V, 5gag:V, 5gah:V, 6gbz:U, 6gc0:U, 6gc4:U, 6gc6:U, 6gc7:U, 6gc8:U, 6gwt:U, 6gxm:U, 6gxn:U, 6gxo:U, 6gxp:U, 6h4n:U, 5h5u:V, 6h58:U, 6h58:UU, 6hrm:U, 8hsp:t, 8htz:t, 8hu1:t, 6i0y:h, 6i7v:DV, 6i7v:CV, 8ifb:t, 8ifc:t, 5iqr:U, 5it8:CV, 5it8:DV, 8j1z:t, 2j28:U, 3j45:U, 3j46:U, 3j5l:U, 5j5b:CV, 5j5b:DV, 3j7z:U, 5j7l:CV, 5j7l:DV, 3j8g:U, 5j88:CV, 5j88:DV, 5j8a:CV, 5j8a:DV, 3j9y:U, 3j9z:LS, 5j91:CV, 5j91:DV, 3ja1:LW, 3jbu:u, 3jbv:u, 3jcd:U, 3jce:U, 3jcj:T, 3jcn:U, 5jc9:CV, 5jc9:DV, 7jss:u, 7jsw:u, 7jsz:u, 5jte:BU, 7jt1:u, 7jt2:u, 7jt3:u, 5ju8:BU, 7k00:t, 7k50:u, 7k51:u, 7k52:u, 7k53:u, 7k54:u, 7k55:u, 5kcr:1Y, 5kcs:1Y, 5kps:U, 5kpv:T, 5kpw:T, 5kpx:T, 5l3p:Y, 6lkq:c, 7lv0:u, 7lvk:c, 5lza:U, 5lzb:U, 5lzc:U, 5lzd:U, 5lze:U, 5lzf:U, 7m5d:U, 5mdv:U, 5mdw:U, 5mdy:U, 5mdz:U, 5mgp:U, 7n1p:LX, 7n2c:LX, 7n2u:LX, 7n2v:LX, 7n30:LX, 7n31:LX, 7nbu:t, 5nco:V, 5np6:s, 7nso:U, 7nsp:U, 7nsq:U, 5nwy:h, 7nwt:U, 7nww:T, 7o19:BU, 7o1a:BU, 7o1c:BU, 5o2r:U, 6o9j:U, 6o9k:U, 7ode:c, 6ofx:u, 6og7:u, 6ogf:u, 6ogg:u, 6ogi:u, 7oif:T, 7oig:T, 7oii:T, 7oiz:t, 7oj0:t, 6om6:U, 6ore:U, 6orl:U, 6osk:U, 6osq:U, 6ost:U, 6ot3:U, 7ot5:T, 7otc:U, 6ouo:U, 8p16:U, 8p17:U, 8p18:U, 7p3k:t, 8peg:x, 8phj:t, 6pj6:c, 7pjs:U, 7pjt:U, 7pju:U, 7pjv:U, 7pjw:U, 7pjx:U, 7pjy:U, 7pjz:U, 8pkl:x, 8pva:t, 7q4k:BU, 8q4f:t, 6q97:U, 6q98:U, 6q9a:U, 8qbt:U, 6qdw:u, 7qg8:h, 7qgh:h, 7qgn:h, 7qgr:h, 8qk7:U, 8qoa:t, 7qq3:c, 6qul:V, 8r6c:t, 8r8m:t, 8rpy:U, 8rpz:U, 8rq0:U, 8rq2:U, 6s0k:V, 7s1g:c, 7s1h:c, 7s1i:c, 7s1j:c, 7s1k:c, 7sa4:U, 7ss9:u, 7ssd:u, 7ssl:u, 7ssn:u, 7sso:u, 7ssw:u, 7st2:u, 7st6:u, 7st7:u, 8syl:W, 6szs:U, 8t5d:U, 8t5h:U, 6tbv:L241, 6tc3:L241, 7tos:L24, 4u1u:BU, 4u1u:DU, 4u1v:BU, 4u1v:DU, 4u20:BU, 4u20:DU, 4u24:BU, 4u24:DU, 4u25:BU, 4u25:DU, 4u26:BU, 4u26:DU, 4u27:BU, 4u27:DU, 5u4i:V, 6u48:CV, 5u9f:23, 5u9g:23, 7ug7:LX, 7uph:t, 8upo:3, 8upr:3, 8uql:3, 8uqm:3, 8uqp:3, 8ur0:3, 8urh:3, 8uri:3, 8urx:3, 8ury:3, 4uy8:U, 5uyk:23, 5uyl:23, 5uym:23, 5uyn:23, 5uyp:23, 5uyq:23, 4v4h:BU, 4v4h:DU, 4v4q:BU, 4v4q:DU, 4v4v:BS, 4v4w:BS, 4v50:BU, 4v50:DU, 4v52:BU, 4v52:DU, 4v53:BU, 4v53:DU, 4v54:BU, 4v54:DU, 4v55:BU, 4v55:DU, 4v56:BU, 4v56:DU, 4v57:BU, 4v57:DU, 4v5b:AU, 4v5b:CU, 4v5h:BU, 4v5y:BU, 4v5y:DU, 4v64:BU, 4v64:DU, 4v65:BO, 4v66:BO, 4v69:BU, 4v6c:BU, 4v6c:DU, 4v6d:BU, 4v6d:DU, 4v6e:BU, 4v6e:DU, 4v6k:AV, 4v6l:BV, 4v6m:BU, 4v6n:AW, 4v6o:BW, 4v6p:BW, 4v6q:BW, 4v6r:BW, 4v6s:AW, 4v6t:BU, 4v6v:BY, 4v6y:BU, 4v6z:BU, 4v70:BU, 4v71:BU, 4v72:BU, 4v73:BU, 4v74:BU, 4v75:BU, 4v76:BU, 4v77:BU, 4v78:BU, 4v79:BU, 4v7a:BU, 4v7b:BU, 4v7c:BW, 4v7d:AX, 4v7i:AU, 4v7s:BU, 4v7s:DU, 4v7t:BU, 4v7t:DU, 4v7u:BU, 4v7u:DU, 4v7v:BU, 4v7v:DU, 4v85:BY, 4v89:BY, 4v9c:BU, 4v9c:DU, 4v9d:CU, 4v9d:DU, 4v9o:AU, 4v9o:CU, 4v9o:EU, 4v9o:GU, 4v9p:AU, 4v9p:CU, 4v9p:EU, 4v9p:GU, 8vs9:L24, 8vsa:L24, 6vu3:3, 6vwl:S, 6vwm:S, 6vwn:S, 6vyq:3, 6vyr:3, 6vys:3, 6vyt:3, 6vyu:3, 6vyw:3, 6vyx:3, 6vyy:3, 6vyz:3, 6vz2:3, 6vz3:3, 6vz5:3, 6vz7:3, 6vzj:3, 8w51:V, 5wdt:U, 6wd0:u, 6wd1:u, 6wd2:u, 6wd3:u, 6wd4:u, 6wd5:u, 6wd6:u, 6wd7:u, 6wd8:u, 6wd9:u, 6wda:u, 6wdb:u, 6wdc:u, 6wdd:u, 6wde:u, 6wdf:u, 6wdg:u, 6wdh:u, 6wdi:u, 6wdj:u, 6wdk:u, 6wdl:u, 6wdm:u, 5we4:U, 5we6:U, 4wf1:BU, 4wf1:DU, 5wf0:U, 5wfk:U, 5wfs:U, 6wnt:u, 6wnv:u, 6wnw:u, 4woi:BU, 4woi:CU, 4www:RU, 4www:YU, 6x6t:3, 6x7f:3, 6x7k:3, 6x9q:3, 6xdq:3, 6xdr:3, 6xgf:3, 6xii:3, 6xij:3, 6xz7:U, 6xza:U2, 6xzb:U2, 6y69:U, 7y7c:t, 7y7d:t, 7y7e:t, 7y7f:t, 7y7g:t, 7y7h:t, 4ybb:CV, 4ybb:DV, 7yla:c, 6ys3:u, 6ysr:U, 6yss:U, 6yst:U, 6ysu:U, 7z20:u, 7zod:u, 7zp8:u, 6ztj:BV, 6ztl:BV, 6ztm:BV, 6ztn:BV, 6zto:BV, 6ztp:BV, 7zta:L241, 6zu1:BV
2 7zq5:u 91 97 0.9381 1.0000 0.9381 6.94e-56 7zq6:u
3 8cd1:U 103 100 0.6598 0.6214 0.6400 3.91e-39 6spb:U, 6spd:U, 6spf:U, 6spg:U, 7unr:W, 7unu:W, 7unv:W, 7unw:W
4 7m4v:T 103 101 0.5773 0.5437 0.5545 8.43e-31 7m4w:T, 7m4x:T, 7m4y:T, 7m4z:T, 7ryf:T, 7ryg:T, 7ryh:T, 7uvv:T, 7uvw:T, 7uvx:T, 7uvy:T, 7uvz:T, 7uw1:T, 6v39:T, 6v3a:T, 6v3b:T, 6v3d:T, 6yhs:Q, 6ysi:Q
5 8rd8:TI 102 102 0.5567 0.5294 0.5294 8.20e-29 8rdv:TI, 8rdw:TI
6 7asn:S 103 99 0.5258 0.4951 0.5152 2.36e-25 7asm:S, 7aso:Z, 7asp:S, 6ddd:G, 6ddg:G, 6fxc:AS, 6fxc:BS, 5hkv:R, 5hl7:R, 6hma:S, 5ngm:AS, 7nhl:X, 7nhm:X, 5nrg:R, 8p2f:X, 8p2g:X, 8p2h:X, 7p48:S, 6s0x:S, 6s0z:S, 6s12:S, 6s13:S, 6sj6:X, 5t7v:L7, 5tcu:L7, 7ttu:G, 7ttw:G, 4wce:R, 4wf9:R, 4wfa:R, 4wfb:R, 6wqn:G, 6wqq:G, 6wrs:G, 8y36:S, 8y37:S, 8y38:S, 8y39:S
7 3j3v:U 103 99 0.4536 0.4272 0.4444 1.38e-22 7aqc:U, 7aqd:U, 7as8:Y, 7as9:Y, 8buu:U, 6ha1:U, 6ha8:U, 6htq:U, 3j3w:U, 3j9w:BX, 5njt:n, 7o5b:t, 7ope:Y, 6ppf:U, 6ppk:U, 8qcq:U, 7qgu:U, 7qh4:U, 8qpp:t, 7qv1:U, 7qv2:U, 7qv3:U, 8r55:t, 8s1p:U, 8s1u:U, 7s9u:U, 7sae:U, 6tnn:n, 6tpq:n
8 7nhk:X 101 99 0.5052 0.4851 0.4949 3.37e-21 6o8w:V, 6o8x:V, 6o8y:V, 6o8z:V, 6o90:V, 7p7q:X, 7p7r:X, 7p7s:X, 7p7t:X, 7p7u:X, 6w6p:V, 6wu9:V
9 6wru:G 89 95 0.4742 0.5169 0.4842 1.08e-20 5li0:X, 5nd8:X, 5nd9:X, 6yef:X
10 8uu6:W 102 99 0.4742 0.4510 0.4646 3.17e-20 8a57:X, 8a5i:X, 8a63:X, 7nhn:X, 8uu4:W, 8uu5:W, 8uu7:W, 8uu8:W, 8uu9:W, 8uua:W
11 6dzi:V 97 98 0.4948 0.4948 0.4898 3.89e-20 6dzp:V, 7f0d:U, 8fr8:1, 8kab:V, 7kgb:U, 7msc:U, 7msh:U, 7msm:U, 7msz:U, 7mt2:U, 7mt3:U, 7mt7:U, 5o60:V, 5o61:V, 7s0s:W, 7sfr:U, 5v7q:U, 5v93:U, 8v9j:W, 8v9k:W, 8v9l:W, 8whx:X, 8why:X, 8wi7:X, 8wi8:X, 8wib:X, 8wic:X, 7xam:V, 8xz3:V, 7y41:V, 5zeb:V, 5zep:V, 5zet:V
12 7jil:U 94 94 0.4845 0.5000 0.5000 1.53e-18
13 6pvk:U 90 95 0.4124 0.4444 0.4211 7.00e-18
14 6xyw:Au 142 91 0.4536 0.3099 0.4835 1.33e-17
15 8fmw:AW 101 101 0.4536 0.4356 0.4356 3.11e-17 8fn2:W
16 5myj:BX 99 99 0.4639 0.4545 0.4545 3.12e-17
17 1sm1:S 113 98 0.4433 0.3805 0.4388 1.70e-15 7a0r:R, 7a0s:R, 7a18:R, 3cf5:R, 2d3o:S, 3dll:R, 5dm6:R, 5dm7:R, 4io9:R, 4ioa:R, 4ioc:R, 5jvg:R, 5jvh:R, 3pio:R, 3pip:R, 4u67:R, 4v4g:BV, 4v4g:DV, 4v4g:FV, 4v4g:HV, 4v4g:JV, 4wfn:R, 2zjp:R, 2zjq:R, 2zjr:R
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20 6z1p:Ay 190 94 0.4124 0.2105 0.4255 5.53e-12
21 7pkt:s 210 94 0.4227 0.1952 0.4362 9.54e-12
22 4v7m:BY 87 87 0.3918 0.4368 0.4368 1.01e-10
23 8crx:t 107 91 0.3918 0.3551 0.4176 3.72e-10 9c4g:t, 8cvm:t
24 5mmi:V 134 96 0.3608 0.2612 0.3646 1.38e-09 6eri:AU, 5h1s:W, 5mlc:W, 5mmm:V, 4v61:BW, 5x8p:V, 5x8t:V
25 7ood:t 96 100 0.3299 0.3333 0.3200 2.82e-08 7p6z:t
26 7pah:t 111 110 0.3608 0.3153 0.3182 3.84e-07 7pai:t, 7paj:t, 7pak:t, 7pal:t, 7pam:t, 7pan:t, 7pao:t, 7paq:t, 7par:t, 7pas:t, 7pat:t, 7pau:t, 7ph9:t, 7pha:t, 7phb:t, 7phc:t, 7pi8:t, 7pi9:t, 7pia:t, 7pib:t, 7pic:t, 7pio:t, 7pip:t, 7piq:t, 7pir:t, 7pis:t, 7pit:t
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31 8qfd:E 201 68 0.2268 0.1095 0.3235 0.042 8fl0:SC
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43 8ip8:PA 130 37 0.1959 0.1462 0.5135 0.69 8ipa:PA, 8ipb:PA, 8jiv:CY, 4v3p:LY, 4v7e:CY
44 5t5h:Z 113 53 0.2062 0.1770 0.3774 0.69
45 8fru:Y 135 52 0.2474 0.1778 0.4615 0.79 8br8:LZ, 8brm:LZ, 8bsi:LZ, 8bsj:LZ, 8btd:LZ, 8btr:LZ, 7pwg:Y, 7pwo:Y2
46 3j79:I 207 39 0.1753 0.0821 0.4359 0.79 3jbn:AI, 3jbo:AI, 3jbp:AI, 8tpu:AI, 5umd:I
47 7eo3:A 282 36 0.1443 0.0496 0.3889 0.99
48 3j79:Z 121 21 0.1031 0.0826 0.4762 1.0 3jbn:AZ, 3jbo:AZ, 3jbp:AZ, 8tpu:AZ, 5umd:Z
49 5xxb:X 124 31 0.1443 0.1129 0.4516 1.1
50 4v8m:BZ 124 64 0.2268 0.1774 0.3438 1.1 8ova:BZ, 8ove:BZ
51 7qiw:a 132 31 0.1546 0.1136 0.4839 1.2 8azw:m, 8b2l:m3, 7qiz:a
52 7oya:E1 206 43 0.1649 0.0777 0.3721 2.0 7oyb:E1
53 4v6w:CE 228 28 0.1237 0.0526 0.4286 2.5 6xu6:CE, 6xu7:CE, 6xu8:CE
54 8i9p:LY 134 50 0.2165 0.1567 0.4200 2.5 8i9r:LY, 8i9t:LY, 8i9v:LY, 8i9w:LY, 8i9x:LY, 8i9y:LY, 8i9z:LY, 8ia0:LY, 7olc:LY, 7old:LY, 8onz:LY, 8oo0:LY, 8pv1:LY, 8pv2:LY, 8pv3:LY, 8pv4:LY, 8pv5:LY, 8pv6:LY, 8pv7:LY, 8pv8:LY, 8pvk:LY, 8pvl:LY, 7z3n:LY, 7z3o:LY
55 3bj1:A 142 63 0.1856 0.1268 0.2857 4.3 3bj1:C, 3bj2:A, 3bj2:C, 3bj3:A, 3bj3:C, 1xq5:A, 1xq5:C
56 8q87:BE 225 43 0.1546 0.0667 0.3488 5.5 8q7z:BE
57 6zu5:LY0 138 50 0.1959 0.1377 0.3800 7.1
58 3wvs:A 393 28 0.1031 0.0254 0.3571 8.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218