9enk A 2.2 BS01 FDA A 1 G71 G73 I74 G75 E94 A95 G101 R102 G120 A121 M122 R123 Y124 S333 V334 L367 W512 L517 A521 F522 G550 E551 A558 W559 V560 A563 G12 G14 I15 G16 E35 A36 G42 R43 G61 A62 M63 R64 Y65 S271 V272 L305 W450 L455 A459 F460 G488 E489 A496 W497 V498 A501 S4S6Z0 39152524 701 SPPGGERVGILGAGIGGLYSALILQSLDVPFEIIEASNRVGGRLFTHKFPNGGKYDYYDVGAMRYPLPKSDDKGNYQPGVMQRVGQLFTYLGMHKQLIPYYFKSNKSPGFQYFNGVRARIGEGSSFDAPALGINSSLIDIGVTKIVNDAVGPFAQALFDDLQKHTTTGWDDMMKNDAYSTRSYFSFKYLPSPSFGLPSEHFSTRVINWLETFDKSTGWYDRGLTETVLEAIAFGEVEVDWRCIDGGSHVLPDTIAAFLHKKGGNAFVMNASVTAIGLENPNKEDSPMVVVAGGQKRKYSHVISTLPLPVLRTVDLKNSKLDIVQSNALRKLQYGPSIKIGILFKEPWWTTGQDKNGEKFDLVGGQSYTDLPIRTVVYPSYGVNTNAPSNTLIASYCWTNDAERMGSLIGTGAATYEEQLEHLVLSNLAAVHNTDYQYLKDRLVDVHSWDWNHNPLTMGAFAFFGPGDFQDLYTSLNRPAANGKLHFAGEALSVRHAWVVGALDSAWRAVYNYLYVTDPAKLPKFFELWGKNAEWFEQ 9enk A 2.2 BS02 PHE A 1 R123 W277 E288 F292 Y457 W459 A558 W559 R64 W218 E229 F233 Y395 W397 A496 W497 S4S6Z0 39152524 702 SPPGGERVGILGAGIGGLYSALILQSLDVPFEIIEASNRVGGRLFTHKFPNGGKYDYYDVGAMRYPLPKSDDKGNYQPGVMQRVGQLFTYLGMHKQLIPYYFKSNKSPGFQYFNGVRARIGEGSSFDAPALGINSSLIDIGVTKIVNDAVGPFAQALFDDLQKHTTTGWDDMMKNDAYSTRSYFSFKYLPSPSFGLPSEHFSTRVINWLETFDKSTGWYDRGLTETVLEAIAFGEVEVDWRCIDGGSHVLPDTIAAFLHKKGGNAFVMNASVTAIGLENPNKEDSPMVVVAGGQKRKYSHVISTLPLPVLRTVDLKNSKLDIVQSNALRKLQYGPSIKIGILFKEPWWTTGQDKNGEKFDLVGGQSYTDLPIRTVVYPSYGVNTNAPSNTLIASYCWTNDAERMGSLIGTGAATYEEQLEHLVLSNLAAVHNTDYQYLKDRLVDVHSWDWNHNPLTMGAFAFFGPGDFQDLYTSLNRPAANGKLHFAGEALSVRHAWVVGALDSAWRAVYNYLYVTDPAKLPKFFELWGKNAEWFEQ 9enk B 2.2 BS01 FDA B 1 G71 G73 I74 G75 E94 A95 G101 R102 G120 A121 M122 R123 Y124 S333 V334 L367 W512 L517 F522 G550 E551 A558 W559 V560 A563 G7 G9 I10 G11 E30 A31 G37 R38 G56 A57 M58 R59 Y60 S263 V264 L297 W442 L447 F452 G480 E481 A488 W489 V490 A493 S4S6Z0 39152524 701 ERVGILGAGIGGLYSALILQSLDVPFEIIEASNRVGGRLFTHKFPNGGKYDYYDVGAMRYPLPKSDDKGNYQPGVMQRVGQLFTYLGMHKQLIPYYFKSNKSPGFQYFNGVRARIGEGSSFDAPALGINSSLIDIGVTKIVNDAVGPFAQALFDDLQKHTTTGWDDMMKNDAYSTRSYFSFKYLPSPSFGLPSEHFSTRVINWLETFDKSTGWYDRGLTETVLEAIAFGEVEVDWRCIDGGSHVLPDTIAAFLHKKAFVMNASVTAIGLENPNKEDSPMVVVAGGQKRKYSHVISTLPLPVLRTVDLKNSKLDIVQSNALRKLQYGPSIKIGILFKEPWWTTGQDKNGEKFDLVGGQSYTDLPIRTVVYPSYGVNTNAPSNTLIASYCWTNDAERMGSLIGTGAATYEEQLEHLVLSNLAAVHNTDYQYLKDRLVDVHSWDWNHNPLTMGAFAFFGPGDFQDLYTSLNRPAANGKLHFAGEALSVRHAWVVGALDSAWRAVYNYLYVTDPAKLPKFFELWGKNAEWFE 9enk B 2.2 BS02 PHE B 1 R123 W277 E288 F292 Y457 W459 A558 W559 R59 W213 E224 F228 Y387 W389 A488 W489 S4S6Z0 39152524 702 ERVGILGAGIGGLYSALILQSLDVPFEIIEASNRVGGRLFTHKFPNGGKYDYYDVGAMRYPLPKSDDKGNYQPGVMQRVGQLFTYLGMHKQLIPYYFKSNKSPGFQYFNGVRARIGEGSSFDAPALGINSSLIDIGVTKIVNDAVGPFAQALFDDLQKHTTTGWDDMMKNDAYSTRSYFSFKYLPSPSFGLPSEHFSTRVINWLETFDKSTGWYDRGLTETVLEAIAFGEVEVDWRCIDGGSHVLPDTIAAFLHKKAFVMNASVTAIGLENPNKEDSPMVVVAGGQKRKYSHVISTLPLPVLRTVDLKNSKLDIVQSNALRKLQYGPSIKIGILFKEPWWTTGQDKNGEKFDLVGGQSYTDLPIRTVVYPSYGVNTNAPSNTLIASYCWTNDAERMGSLIGTGAATYEEQLEHLVLSNLAAVHNTDYQYLKDRLVDVHSWDWNHNPLTMGAFAFFGPGDFQDLYTSLNRPAANGKLHFAGEALSVRHAWVVGALDSAWRAVYNYLYVTDPAKLPKFFELWGKNAEWFE 9enk C 2.2 BS01 FDA C 1 G71 G73 I74 G75 E94 A95 G101 R102 G120 A121 M122 R123 Y124 S333 V334 L367 W512 F522 G550 E551 A558 W559 V560 A563 G8 G10 I11 G12 E31 A32 G38 R39 G57 A58 M59 R60 Y61 S264 V265 L298 W443 F453 G481 E482 A489 W490 V491 A494 S4S6Z0 39152524 701 GERVGILGAGIGGLYSALILQSLDVPFEIIEASNRVGGRLFTHKFPNGGKYDYYDVGAMRYPLPKSDDKGNYQPGVMQRVGQLFTYLGMHKQLIPYYFKSNKSPGFQYFNGVRARIGEGSSFDAPALGINSSLIDIGVTKIVNDAVGPFAQALFDDLQKHTTTGWDDMMKNDAYSTRSYFSFKYLPSPSFGLPSEHFSTRVINWLETFDKSTGWYDRGLTETVLEAIAFGEVEVDWRCIDGGSHVLPDTIAAFLHKNAFVMNASVTAIGLENPNKEDSPMVVVAGGQKRKYSHVISTLPLPVLRTVDLKNSKLDIVQSNALRKLQYGPSIKIGILFKEPWWTTGQDKNGEKFDLVGGQSYTDLPIRTVVYPSYGVNTNAPSNTLIASYCWTNDAERMGSLIGTGAATYEEQLEHLVLSNLAAVHNTDYQYLKDRLVDVHSWDWNHNPLTMGAFAFFGPGDFQDLYTSLNRPAANGKLHFAGEALSVRHAWVVGALDSAWRAVYNYLYVTDPAKLPKFFELWGKNAEWFEQ 9enk C 2.2 BS02 PHE C 1 R123 W277 E288 F292 Y457 W459 A558 W559 R60 W214 E225 F229 Y388 W390 A489 W490 S4S6Z0 39152524 702 GERVGILGAGIGGLYSALILQSLDVPFEIIEASNRVGGRLFTHKFPNGGKYDYYDVGAMRYPLPKSDDKGNYQPGVMQRVGQLFTYLGMHKQLIPYYFKSNKSPGFQYFNGVRARIGEGSSFDAPALGINSSLIDIGVTKIVNDAVGPFAQALFDDLQKHTTTGWDDMMKNDAYSTRSYFSFKYLPSPSFGLPSEHFSTRVINWLETFDKSTGWYDRGLTETVLEAIAFGEVEVDWRCIDGGSHVLPDTIAAFLHKNAFVMNASVTAIGLENPNKEDSPMVVVAGGQKRKYSHVISTLPLPVLRTVDLKNSKLDIVQSNALRKLQYGPSIKIGILFKEPWWTTGQDKNGEKFDLVGGQSYTDLPIRTVVYPSYGVNTNAPSNTLIASYCWTNDAERMGSLIGTGAATYEEQLEHLVLSNLAAVHNTDYQYLKDRLVDVHSWDWNHNPLTMGAFAFFGPGDFQDLYTSLNRPAANGKLHFAGEALSVRHAWVVGALDSAWRAVYNYLYVTDPAKLPKFFELWGKNAEWFEQ 9enk D 2.2 BS01 FDA D 1 G71 G73 I74 G75 E94 A95 G101 R102 G120 A121 M122 R123 Y124 S333 V334 L367 W512 L517 F522 G550 E551 A558 W559 V560 A563 G8 G10 I11 G12 E31 A32 G38 R39 G57 A58 M59 R60 Y61 S268 V269 L302 W447 L452 F457 G485 E486 A493 W494 V495 A498 S4S6Z0 39152524 701 GERVGILGAGIGGLYSALILQSLDVPFEIIEASNRVGGRLFTHKFPNGGKYDYYDVGAMRYPLPKSDDKGNYQPGVMQRVGQLFTYLGMHKQLIPYYFKSNKSPGFQYFNGVRARIGEGSSFDAPALGINSSLIDIGVTKIVNDAVGPFAQALFDDLQKHTTTGWDDMMKNDAYSTRSYFSFKYLPSPSFGLPSEHFSTRVINWLETFDKSTGWYDRGLTETVLEAIAFGEVGEVDWRCIDGGSHVLPDTIAAFLHKKGGNAFVMNASVTAIGLENPNKEDSPMVVVAGGQKRKYSHVISTLPLPVLRTVDLKNSKLDIVQSNALRKLQYGPSIKIGILFKEPWWTTGQDKNGEKFDLVGGQSYTDLPIRTVVYPSYGVNTNAPSNTLIASYCWTNDAERMGSLIGTGAATYEEQLEHLVLSNLAAVHNTDYQYLKDRLVDVHSWDWNHNPLTMGAFAFFGPGDFQDLYTSLNRPAANGKLHFAGEALSVRHAWVVGALDSAWRAVYNYLYVTDPAKLPKFFELWGKNAEWFE 9enk D 2.2 BS02 PHE D 1 R123 W277 E288 F292 Y457 W459 A558 W559 R60 W214 E225 F229 Y392 W394 A493 W494 S4S6Z0 39152524 702 GERVGILGAGIGGLYSALILQSLDVPFEIIEASNRVGGRLFTHKFPNGGKYDYYDVGAMRYPLPKSDDKGNYQPGVMQRVGQLFTYLGMHKQLIPYYFKSNKSPGFQYFNGVRARIGEGSSFDAPALGINSSLIDIGVTKIVNDAVGPFAQALFDDLQKHTTTGWDDMMKNDAYSTRSYFSFKYLPSPSFGLPSEHFSTRVINWLETFDKSTGWYDRGLTETVLEAIAFGEVGEVDWRCIDGGSHVLPDTIAAFLHKKGGNAFVMNASVTAIGLENPNKEDSPMVVVAGGQKRKYSHVISTLPLPVLRTVDLKNSKLDIVQSNALRKLQYGPSIKIGILFKEPWWTTGQDKNGEKFDLVGGQSYTDLPIRTVVYPSYGVNTNAPSNTLIASYCWTNDAERMGSLIGTGAATYEEQLEHLVLSNLAAVHNTDYQYLKDRLVDVHSWDWNHNPLTMGAFAFFGPGDFQDLYTSLNRPAANGKLHFAGEALSVRHAWVVGALDSAWRAVYNYLYVTDPAKLPKFFELWGKNAEWFE