8wr4 A 3.07 BS01 dna F 0 K63 K569 K1161 D1162 T1163 K1177 K1186 E1370 K1390 S1396 Q1397 K63 K569 K931 D932 T933 K947 K956 E1140 K1160 S1166 Q1167 38811729 2 ~ 44 MIKNILGLALGTNSIGWALVKQDFENKQGEILGMGSRIIPMSQDILGDFGKGNSVSQTAERTKYRSVRRLRERFLLRRERLHRVLYILNFLPEHYASQIDFEKRLGKFKVETEPKLVWKNTDGQFSFLFQNSFNEMLEDFKAAGQELKIPYDWTIYHLRKKAISQKIEKEELAWILLNFNHKRGYYQLRGEDFEEEKDKTFVRLKVDRIVDSGENVKGKILYDVYFENGWKYDKQVVKTEDWVDRTKEFIVSESILKNGETKRTFKAVDSEKDWIAIKTKTEQEIEHSHKTVGTYIYETLLQNPKQKIKGKLVRTIERKFYKEELRQILEKQKEFHQELQSDDLYNDCIRELYRNNEVHQLTLRKKDFVHLFMEDIIFYQRPLRSQKSSVSNCTLEFRKYKGENGAEHTQYLKAIPKSNPYYQEFRLWQWIFNLNLYTKDNDENVTKVFLNTTQDFENLFEFLNTRKEVDQKALLKHFKLNEKTHRWNFVEDKKYPCNETKTMISSRLDKVENISDDFLTRDIEQKIWHIIYSVNDKVEYEKALKSFARKHHLDESSFFEAFRKFPPFKSEYGSFSEKAIKKLLPLMRLGKYWNYAEIDKYSRERIQKIITGEYDENIKDKVREKSVHLTIENDFQGLQLWLAQYIVYGRHSEASMIGKWNSANDLEVFLKDFKQHSLRNPIVEQVITETLRVVKDIWLKYGNGTKDFFNEIHIELGDTRYISKYISGILSNIVRVEDGSDEGVNSKNIVPGNGKITTQLKQDWGLNDVWNDLILPRFERMNQLTNSKDFTAWNENHQKFLPTVPIEFSKGFSKKRIDHRHHALDALVIACATTDHVNLLNNQSAKSDTKRYDLKKKLMKFPKQFLKPWEKFTVDAKHNLESIIVSFKQNLRVINKATNYYEKYVEKDGTKNKERVEQAGTNWAIRKPMHKDTVSGKVDLPWVKVPKGKILTATRKSLDSSFDLKSIGSITDTGIQKILKNYLAFKDGNPELAFSPEGIDDLNKNIEKYNDGKPHQPINKVRVFELGSKFQVGQTGNKKGKYVEAAKGTNLFFAVYEDEKGKRSYETIPLNEVIERQKQGLTSVPLENEKGSRLLFDLSPNDLVYVPEIDENIDSNFVFSNLNKEKISRIYKVEKTSGTECYFVRQDIAYLIKQYDAKTKIGELESQNKLQVTMTDDRIRITDTCVKINCDRLGNINFITKEKIKQIFNEFR 8wr4 A 3.07 BS02 rna O 0 S56 T58 R61 T62 Y64 R65 R68 R69 L70 R71 R73 L76 R78 R80 R83 E113 W118 F125 K148 I149 P150 Y151 D152 W153 Y156 N178 H181 K182 R183 G184 K307 I308 K309 G310 R314 N355 N356 V358 H359 T362 K366 D375 Y379 Q380 R381 L383 R384 S385 K387 R398 K399 Y400 Q410 W528 H529 Y532 S533 E539 K542 S546 E577 K578 K581 Q675 H676 R679 R692 K1118 R1122 N1125 K1126 N1129 Y1131 E1132 Y1134 K1143 R1145 Q1148 N1152 W1153 I1155 R1156 K1157 P1158 M1159 H1160 V1164 V1168 D1169 R1185 T1201 D1202 T1203 G1204 K1243 P1244 H1245 Q1246 P1247 N1249 K1250 R1252 V1262 T1265 N1267 K1268 G1270 K1271 S56 T58 R61 T62 Y64 R65 R68 R69 L70 R71 R73 L76 R78 R80 R83 E113 W118 F125 K148 I149 P150 Y151 D152 W153 Y156 N178 H181 K182 R183 G184 K307 I308 K309 G310 R314 N355 N356 V358 H359 T362 K366 D375 Y379 Q380 R381 L383 R384 S385 K387 R398 K399 Y400 Q410 W528 H529 Y532 S533 E539 K542 S546 E577 K578 K581 Q675 H676 R679 R692 K888 R892 N895 K896 N899 Y901 E902 Y904 K913 R915 Q918 N922 W923 I925 R926 K927 P928 M929 H930 V934 V938 D939 R955 T971 D972 T973 G974 K1013 P1014 H1015 Q1016 P1017 N1019 K1020 R1022 V1032 T1035 N1037 K1038 G1040 K1041 38811729 10 ~ 123 MIKNILGLALGTNSIGWALVKQDFENKQGEILGMGSRIIPMSQDILGDFGKGNSVSQTAERTKYRSVRRLRERFLLRRERLHRVLYILNFLPEHYASQIDFEKRLGKFKVETEPKLVWKNTDGQFSFLFQNSFNEMLEDFKAAGQELKIPYDWTIYHLRKKAISQKIEKEELAWILLNFNHKRGYYQLRGEDFEEEKDKTFVRLKVDRIVDSGENVKGKILYDVYFENGWKYDKQVVKTEDWVDRTKEFIVSESILKNGETKRTFKAVDSEKDWIAIKTKTEQEIEHSHKTVGTYIYETLLQNPKQKIKGKLVRTIERKFYKEELRQILEKQKEFHQELQSDDLYNDCIRELYRNNEVHQLTLRKKDFVHLFMEDIIFYQRPLRSQKSSVSNCTLEFRKYKGENGAEHTQYLKAIPKSNPYYQEFRLWQWIFNLNLYTKDNDENVTKVFLNTTQDFENLFEFLNTRKEVDQKALLKHFKLNEKTHRWNFVEDKKYPCNETKTMISSRLDKVENISDDFLTRDIEQKIWHIIYSVNDKVEYEKALKSFARKHHLDESSFFEAFRKFPPFKSEYGSFSEKAIKKLLPLMRLGKYWNYAEIDKYSRERIQKIITGEYDENIKDKVREKSVHLTIENDFQGLQLWLAQYIVYGRHSEASMIGKWNSANDLEVFLKDFKQHSLRNPIVEQVITETLRVVKDIWLKYGNGTKDFFNEIHIELGDTRYISKYISGILSNIVRVEDGSDEGVNSKNIVPGNGKITTQLKQDWGLNDVWNDLILPRFERMNQLTNSKDFTAWNENHQKFLPTVPIEFSKGFSKKRIDHRHHALDALVIACATTDHVNLLNNQSAKSDTKRYDLKKKLMKFPKQFLKPWEKFTVDAKHNLESIIVSFKQNLRVINKATNYYEKYVEKDGTKNKERVEQAGTNWAIRKPMHKDTVSGKVDLPWVKVPKGKILTATRKSLDSSFDLKSIGSITDTGIQKILKNYLAFKDGNPELAFSPEGIDDLNKNIEKYNDGKPHQPINKVRVFELGSKFQVGQTGNKKGKYVEAAKGTNLFFAVYEDEKGKRSYETIPLNEVIERQKQGLTSVPLENEKGSRLLFDLSPNDLVYVPEIDENIDSNFVFSNLNKEKISRIYKVEKTSGTECYFVRQDIAYLIKQYDAKTKIGELESQNKLQVTMTDDRIRITDTCVKINCDRLGNINFITKEKIKQIFNEFR 8wr4 A 3.07 BS03 dna S 0 Q43 D44 E1255 G1257 E1274 K1277 G1278 N1280 T1366 S1367 Q43 D44 E1025 G1027 E1044 K1047 G1048 N1050 T1136 S1137 38811729 12 ~ 47 MIKNILGLALGTNSIGWALVKQDFENKQGEILGMGSRIIPMSQDILGDFGKGNSVSQTAERTKYRSVRRLRERFLLRRERLHRVLYILNFLPEHYASQIDFEKRLGKFKVETEPKLVWKNTDGQFSFLFQNSFNEMLEDFKAAGQELKIPYDWTIYHLRKKAISQKIEKEELAWILLNFNHKRGYYQLRGEDFEEEKDKTFVRLKVDRIVDSGENVKGKILYDVYFENGWKYDKQVVKTEDWVDRTKEFIVSESILKNGETKRTFKAVDSEKDWIAIKTKTEQEIEHSHKTVGTYIYETLLQNPKQKIKGKLVRTIERKFYKEELRQILEKQKEFHQELQSDDLYNDCIRELYRNNEVHQLTLRKKDFVHLFMEDIIFYQRPLRSQKSSVSNCTLEFRKYKGENGAEHTQYLKAIPKSNPYYQEFRLWQWIFNLNLYTKDNDENVTKVFLNTTQDFENLFEFLNTRKEVDQKALLKHFKLNEKTHRWNFVEDKKYPCNETKTMISSRLDKVENISDDFLTRDIEQKIWHIIYSVNDKVEYEKALKSFARKHHLDESSFFEAFRKFPPFKSEYGSFSEKAIKKLLPLMRLGKYWNYAEIDKYSRERIQKIITGEYDENIKDKVREKSVHLTIENDFQGLQLWLAQYIVYGRHSEASMIGKWNSANDLEVFLKDFKQHSLRNPIVEQVITETLRVVKDIWLKYGNGTKDFFNEIHIELGDTRYISKYISGILSNIVRVEDGSDEGVNSKNIVPGNGKITTQLKQDWGLNDVWNDLILPRFERMNQLTNSKDFTAWNENHQKFLPTVPIEFSKGFSKKRIDHRHHALDALVIACATTDHVNLLNNQSAKSDTKRYDLKKKLMKFPKQFLKPWEKFTVDAKHNLESIIVSFKQNLRVINKATNYYEKYVEKDGTKNKERVEQAGTNWAIRKPMHKDTVSGKVDLPWVKVPKGKILTATRKSLDSSFDLKSIGSITDTGIQKILKNYLAFKDGNPELAFSPEGIDDLNKNIEKYNDGKPHQPINKVRVFELGSKFQVGQTGNKKGKYVEAAKGTNLFFAVYEDEKGKRSYETIPLNEVIERQKQGLTSVPLENEKGSRLLFDLSPNDLVYVPEIDENIDSNFVFSNLNKEKISRIYKVEKTSGTECYFVRQDIAYLIKQYDAKTKIGELESQNKLQVTMTDDRIRITDTCVKINCDRLGNINFITKEKIKQIFNEFR 8wr4 B 3.07 BS01 dna F 0 K257 K1277 K257 K1277 38811729 2 ~ 44 MIKNILGLALGTNSIGWALVKQDFENKQGEILGMGSRIIPMSQDILGDFGKGNSVSQTAERTKYRSVRRLRERFLLRRERLHRVLYILNFLPEHYASQIDFEKRLGKFKVETEPKLVWKNTDGQFSFLFQNSFNEMLEDFKAAGQELKIPYDWTIYHLRKKAISQKIEKEELAWILLNFNHKRGYYQLRGEDFEEEKDKTFVRLKVDRIVDSGENVKGKILYDVYFENGWKYDKQVVKTEDWVDRTKEFIVSESILKNGETKRTFKAVDSEKDWIAIKTKTEQEIEHSHKTVGTYIYETLLQNPKQKIKGKLVRTIERKFYKEELRQILEKQKEFHQELQSDDLYNDCIRELYRNNEVHQLTLRKKDFVHLFMEDIIFYQRPLRSQKSSVSNCTLEFRKYKGENGAEHTQYLKAIPKSNPYYQEFRLWQWIFNLNLYTKDNDENVTKVFLNTTQDFENLFEFLNTRKEVDQKALLKHFKLNEKTHRWNFVEDKKYPCNETKTMISSRLDKVENISDDFLTRDIEQKIWHIIYSVNDKVEYEKALKSFARKHHLDESSFFEAFRKFPPFKSEYGSFSEKAIKKLLPLMRLGKYWNYAEIDKYSRERIQKIITGEYDENIKDKVREKSVHLTIENDFQGLQLWLAQYIVYGRHSEASMIGKWNSANDLEVFLKDFKQHSLRNPIVEQVITETLRVVKDIWLKYGNGTKDFFNEIHIELGREMKLPADDRKKLTNQITENENTNLRIKALLAEMMNDHSVENVRPFSPMQQEILKIYEDGVLKSDIEIEDDILKISKTAQPSSSDLKRYKLWLEQKYKSPYTGQIIPLNKLFTPEYEIEAIIPQSRYFDDSFSNKIICESAVNKLKDNYIGLGFIKQFGGTIIELGFGKSVKVFDTEEYEDFVKKHYANNRGKRNKLLMEDIPEKMIERQLNDTRYISKYISGILSNIVRVEDGSDEGVNSKNIVPGNGKITTQLKQDWGLNDVWNDLILPRFERMNQLTNSKDFTAWNENHQKFLPTVPIEFSKGFSKKRIDHRHHALDALVIACATTDHVNLLNNQSAKSDTKRYDLKKKLMKFEKVVYHHTQTGEKIEREIPKQFLKPWEKFTVDAKHNLESIIVSFKQNLRVINKATNYYEKYVEKDGTKNKERVEQAGTNWAIRKPMHKDTVSGKVDLPWVKVPKGKILTATRKSLDSSFDLKSIGSITDTGIQKILKNYLAFKDGNPELAFSPEGIDDLNKNIEKYNDGKPHQPINKVRVFELGSKFQVGQTGNKKGKYVEAAKGTNLFFAVYEDEKGKRSYETIPLNEVIERQKQGLTSVPLENEKGSRLLFDLSPNDLVYVPEIDENIDSNFVFSNLNKEKISRIYKVEKTSGTECYFVRQDIAYLIKQYDAKTKIGELESQNKLQVTMTDDRIRITDTCVKINCDRLGNINFITKEKIKQIFNEFR 8wr4 B 3.07 BS02 rna N 0 S54 T58 R61 T62 Y64 R65 R68 R69 L70 R71 R73 L76 R78 R80 K107 K115 W118 F125 K148 Y151 D152 W153 W174 N178 H181 K182 R183 G184 K307 I308 K309 G310 R314 T315 Y353 N356 D375 Y379 Q380 R381 L383 R384 S385 Q386 S388 R398 Y400 E403 Q410 K417 N488 F489 H529 I530 Y532 S533 E539 K542 A543 K550 E571 Y572 E577 K578 Q675 H676 R679 R692 P723 T931 R932 Y933 R1122 N1125 K1126 N1129 Y1130 Y1131 E1132 K1133 K1143 R1145 Q1148 N1152 W1153 I1155 R1156 P1158 M1159 H1160 V1164 D1169 R1185 T1201 D1202 T1203 G1204 K1243 P1244 H1245 Q1246 P1247 N1249 K1250 R1252 V1262 T1265 K1268 G1270 K1271 K1308 S54 T58 R61 T62 Y64 R65 R68 R69 L70 R71 R73 L76 R78 R80 K107 K115 W118 F125 K148 Y151 D152 W153 W174 N178 H181 K182 R183 G184 K307 I308 K309 G310 R314 T315 Y353 N356 D375 Y379 Q380 R381 L383 R384 S385 Q386 S388 R398 Y400 E403 Q410 K417 N488 F489 H529 I530 Y532 S533 E539 K542 A543 K550 E571 Y572 E577 K578 Q675 H676 R679 R692 P723 T931 R932 Y933 R1122 N1125 K1126 N1129 Y1130 Y1131 E1132 K1133 K1143 R1145 Q1148 N1152 W1153 I1155 R1156 P1158 M1159 H1160 V1164 D1169 R1185 T1201 D1202 T1203 G1204 K1243 P1244 H1245 Q1246 P1247 N1249 K1250 R1252 V1262 T1265 K1268 G1270 K1271 K1308 38811729 7 ~ 123 MIKNILGLALGTNSIGWALVKQDFENKQGEILGMGSRIIPMSQDILGDFGKGNSVSQTAERTKYRSVRRLRERFLLRRERLHRVLYILNFLPEHYASQIDFEKRLGKFKVETEPKLVWKNTDGQFSFLFQNSFNEMLEDFKAAGQELKIPYDWTIYHLRKKAISQKIEKEELAWILLNFNHKRGYYQLRGEDFEEEKDKTFVRLKVDRIVDSGENVKGKILYDVYFENGWKYDKQVVKTEDWVDRTKEFIVSESILKNGETKRTFKAVDSEKDWIAIKTKTEQEIEHSHKTVGTYIYETLLQNPKQKIKGKLVRTIERKFYKEELRQILEKQKEFHQELQSDDLYNDCIRELYRNNEVHQLTLRKKDFVHLFMEDIIFYQRPLRSQKSSVSNCTLEFRKYKGENGAEHTQYLKAIPKSNPYYQEFRLWQWIFNLNLYTKDNDENVTKVFLNTTQDFENLFEFLNTRKEVDQKALLKHFKLNEKTHRWNFVEDKKYPCNETKTMISSRLDKVENISDDFLTRDIEQKIWHIIYSVNDKVEYEKALKSFARKHHLDESSFFEAFRKFPPFKSEYGSFSEKAIKKLLPLMRLGKYWNYAEIDKYSRERIQKIITGEYDENIKDKVREKSVHLTIENDFQGLQLWLAQYIVYGRHSEASMIGKWNSANDLEVFLKDFKQHSLRNPIVEQVITETLRVVKDIWLKYGNGTKDFFNEIHIELGREMKLPADDRKKLTNQITENENTNLRIKALLAEMMNDHSVENVRPFSPMQQEILKIYEDGVLKSDIEIEDDILKISKTAQPSSSDLKRYKLWLEQKYKSPYTGQIIPLNKLFTPEYEIEAIIPQSRYFDDSFSNKIICESAVNKLKDNYIGLGFIKQFGGTIIELGFGKSVKVFDTEEYEDFVKKHYANNRGKRNKLLMEDIPEKMIERQLNDTRYISKYISGILSNIVRVEDGSDEGVNSKNIVPGNGKITTQLKQDWGLNDVWNDLILPRFERMNQLTNSKDFTAWNENHQKFLPTVPIEFSKGFSKKRIDHRHHALDALVIACATTDHVNLLNNQSAKSDTKRYDLKKKLMKFEKVVYHHTQTGEKIEREIPKQFLKPWEKFTVDAKHNLESIIVSFKQNLRVINKATNYYEKYVEKDGTKNKERVEQAGTNWAIRKPMHKDTVSGKVDLPWVKVPKGKILTATRKSLDSSFDLKSIGSITDTGIQKILKNYLAFKDGNPELAFSPEGIDDLNKNIEKYNDGKPHQPINKVRVFELGSKFQVGQTGNKKGKYVEAAKGTNLFFAVYEDEKGKRSYETIPLNEVIERQKQGLTSVPLENEKGSRLLFDLSPNDLVYVPEIDENIDSNFVFSNLNKEKISRIYKVEKTSGTECYFVRQDIAYLIKQYDAKTKIGELESQNKLQVTMTDDRIRITDTCVKINCDRLGNINFITKEKIKQIFNEFR